Abstract:
:Traditionally, Doppler ultrasound has been used to estimate blood flow as the mean velocity multiplied by the vessel area, but this is subject to significant errors and may be difficult to perform accurately. Microbubbles, developed as contrast agents for ultrasound, were initially envisaged as useful for increasing the intensity of echoes and thus rescuing Doppler studies that were technical failures because of attenuated signals or very slow flow. However, they can act as tracers and, by analogy with isotope techniques, can be used to measure blood flow with transit-time methods which exploit both arterial and venous time-intensity data. An acceptable compromise is to acquire both a tissue intensity curve and one from the feeding artery. The transit of microbubbles across an organ or tissue can be used to estimate haemodynamic alterations, e.g. the arterialisation of the supply to the liver in malignancies and cirrhosis and the delayed arterio-venous transit in the transplant kidney during rejection. The fragility of microbubbles can be turned to advantage by being exploited to create a negative bolus by exposing a tissue slice to a high power beam. The rate of refilling of this slice by circulating microbubbles can then be followed with a low-intensity monitoring beam and the resulting rising exponential curve analysed to extract indices of both the reperfusion rate (the slope) and the fractional vascular volume (the asymptote). The product of these is a measure of true tissue perfusion.
journal_name
Eur Radioljournal_title
European radiologyauthors
Cosgrove D,Eckersley R,Blomley M,Harvey Cdoi
10.1007/s003300100985subject
Has Abstractpub_date
2001-01-01 00:00:00pages
1338-44issue
8eissn
0938-7994issn
1432-1084journal_volume
11pub_type
杂志文章,评审abstract:OBJECTIVES:To verify the association between EGFR status and clinical response to microwave ablation (MWA) and survival. METHODS:NSCLC patients with known EGFR status and treated with MWA in combination with chemotherapy were retrospectively enrolled in the study. RESULTS:A total of 61 patients were recruited. EGFR m...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4474-4
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Recent studies have created awareness that facial features can be reconstructed from high-resolution MRI. Therefore, data sharing in neuroimaging requires special attention to protect participants' privacy. Facial features removal (FFR) could alleviate these concerns. We assessed the impact of three FFR meth...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06459-3
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:To compare the diagnostic accuracy of 3D versus 2D contrast-enhanced vessel-wall (CE-VW) MRI of extracranial and intracranial arteries in the diagnosis of GCA. METHODS:This prospective two-center study was approved by a national research ethics board and enrolled participants from December 2014 to October 2...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06536-7
更新日期:2020-04-01 00:00:00
abstract::Increasing beam energies are well established as a radiation dose-reducing tool in diagnostic radiology. This has led to useful recommendations by the Commission of European Communities (CEC) for appropriate kVp values to be employed for a variety of examinations. The current work tests the hypothesis that kVp levels ...
journal_title:European radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00330-002-1810-7
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVES:We see a high incidence of plunging ranulas, particularly in Maori and Polynesian populations. We have investigated the usefulness of ultrasound in the diagnosis and management of plunging ranulas and present our findings. METHODS:Thirty-three new cases were examined over 4 years (June 2004 to October 2008)...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1666-1
更新日期:2010-06-01 00:00:00
abstract::The blood-ocular barrier (BOB) shares similar neuroepithelial origin, microanatomy and functions with the blood-brain barrier. There are many natural (e. g. diabetes, hypertension) or iatrogenic (chemotherapy, retinal photocoagulation) conditions which can cause a BOB breakdown, resulting in visual acuity impairment o...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050121
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:To implement, examine, and compare three multichannel transmit/receive coil configurations for cardiovascular MR (CMR) at 7T. METHODS:Three radiofrequency transmit-receive (TX/RX) coils with 4-, 8-, and 16-coil elements were used. Ten healthy volunteers (seven males, age 28 ± 4 years) underwent CMR at 7T. F...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2487-1
更新日期:2012-10-01 00:00:00
abstract::We examined 20 prediagnostic CTs from 16 patients for whom the diagnosis of pancreatic cancer was delayed until full diagnostic CT was performed. Three radiologists independently reviewed the prediagnostic CTs along with 50 CTs of control subjects, including patients without pancreatic disease (n = 38) or with chronic...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1422-6
更新日期:2009-10-01 00:00:00
abstract::In the absence of reliable supplies of X-ray film, direct fluoroscopy is still extensively used in Albania, with chest radiology a particularly common application. This paper aims to quantify both patient skin dose and the risk-related quantity effective dose for direct fluoroscopy units based in seven different Alban...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000462
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To compare imaging findings with histopathology in AML without visible fat (AMLwvf). MATERIAL AND METHODS:With IRB approval, we identified 18 AMLwvf that underwent CT between 2002-2014. A radiologist measured NECT-attenuation, corticomedullary (CM) and nephrographic (NG) enhancement, echogenicity relative to...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3851-8
更新日期:2016-02-01 00:00:00
abstract::Tumors of the hand and wrist most commonly result from dystrophic lesions and hamartomas. Neoplastic lesions are rare. Imaging modalities are required for their detection and accurate location, careful assessment of the internal structure and borders, evaluation of the relation with surrounding tendons, nerves, and ve...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300000751
更新日期:2001-01-01 00:00:00
abstract::Our objective was to evaluate the hemolytic effect of stents and stent grafts in an in vitro flow model. The model consisted of silicone tubings. Pulsatile flow was delivered at 1170 ml/min. Diluted packed erythrocytes were used (hematocrit of 33%). The Palmaz, MegaLink stents or Passager, Hemobahn stent grafts were p...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1664-z
更新日期:2003-06-01 00:00:00
abstract::The effect of stereotactic thalamotomy was assessed with pre- and postoperative functional magnetic resonance imaging (fMRI) under motor stimulation. A patient with unilateral essential tremor (ET) of the left arm underwent stereotactically guided thalamotomy of the right ventral intermediate thalamic nucleus (VIM). F...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0211-8
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVES:To demonstrate the feasibility of using chemical exchange saturation transfer (CEST) imaging to detect Parkinson's disease (PD) in patients at 3 Tesla. METHODS:Twenty-seven PD patients (17 men and 10 women; age range, 54-77 years) and 22 age-matched normal controls (13 men and 9 women; age range, 55-73 year...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3241-7
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:To determine the diagnostic performance of a deep learning (DL) model in evaluating myometrial invasion (MI) depth on T2-weighted imaging (T2WI)-based endometrial cancer (EC) MR imaging (ECM). METHODS:We retrospectively enrolled 530 patients with pathologically proven EC at our institution between January 1,...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-06870-1
更新日期:2020-09-01 00:00:00
abstract::Our objective was to determine the value of the Ottawa knee rules when applied by users with different levels of clinical training. We used a prospective patient survey by the medical students and surgery residents of a European university trauma centre. The study group consisted of 261 eligible patients who presented...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-001-1198-9
更新日期:2002-05-01 00:00:00
abstract::An electromagnetic-based tracking and navigation system was evaluated for interventional radiology. The electromagnetic tracking system (CAPPA IRAD EMT, CASinnovations, Erlangen, Germany) was used for real-time monitoring of punctures of the lumbar facet joints and intervertebral disks in a spine phantom, three pig ca...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-008-1227-z
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:To compare the performance of synthetic mammography (SM) and digital mammography (DM) with digital breast tomosynthesis (DBT) or alone for the evaluation of microcalcifications. METHODS:This retrospective study includes 198 mammography cases, all with DM, SM, and DBT images, from January to October 2013. Thr...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5585-x
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was to histologically compare chondrotoxicity in surgically harvested intervertebral discs (IVDs) of patients following discoblock, discography, or no preoperative intervention. METHODS:Thirty patients (IVD degeneration Modic ≥ 2°, Pfirrmann 3° or 4°) at L4/5 or L5/S1 who were p...
journal_title:European radiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00330-016-4358-7
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:To evaluate thread sign of biliary intraductal papillary mucinous neoplasm (B-IPMN) on magnetic resonance imaging (MRI). METHODS:Thread sign was defined as intraductal linear or curvilinear hypointense striations. Two radiologists independently evaluated the presence and location of thread sign on MR cholan...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-4158-5
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVES:To evaluate early post-operative magnetic resonance (EPMR) as a prognostic tool after resection of glioblastoma. METHODS:Sixty EPMR examinations were evaluated for perioperative infarct, tumour growth between diagnosis and EPMR, contrast enhancement pattern, and extent of resection (EOR). The EOR was approa...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3914-x
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:To assess the relationship between white matter (WM) integrity and clinical variables in tinnitus patients using diffusion tensor imaging (DTI). METHODS:Sixty-seven tinnitus patients and 39 healthy controls were enrolled in this study. The tinnitus duration, laterality, pitch and characteristics, and two psy...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-4034-3
更新日期:2016-07-01 00:00:00
abstract::Diffusion MRI has mainly been used for detection of acute ischemia, and for distinction of cytotoxic and vasogenic edema. We applied diffusion MRI in patients with tuberous sclerosis in order to evaluate diffusion imaging characteristics of parenchymal changes. Five children with known tuberous sclerosis were included...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300101029
更新日期:2002-01-01 00:00:00
abstract::Circumscribed radiolucencies within the vertebral bones can be due to a variety of changes including benign and malignant tumours or tumour-like lesions. Radiolucencies due to degenerative intraosseous pneumatocyst are very uncommon but have to be taken into the differential diagnosis in well-circumscribed lytic lesio...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000490
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To validate three proposed definitions of the "solid" component of subsolid nodules, as compared to CT histograms and the use of different window settings, for discriminating the invasiveness of adenocarcinomas in a manner that facilitates routine clinical assessment. METHODS:We retrospectively analyzed 328 ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5778-3
更新日期:2019-04-01 00:00:00
abstract::The peritoneum is a mesothelial lining of the abdominal cavity (parietal) and intraperitoneal viscera (visceral). The cavity contains a small amount of fluid, which circulates from cephalad to caudal to cephalad, influenced by negative pressure under the diaphragm during exhalation, gravity, and bowel peristalsis. Per...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300100998
更新日期:2001-01-01 00:00:00
abstract::Ultrasound has emerged as the primary imaging modality in conditions where either renal obstruction or renal medical disease is suspected on the basis of clinical and laboratory findings. In urinary tract obstruction, pathophysiologic changes affecting the pressure in the collecting system and kidney perfusion are wel...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300101011
更新日期:2001-01-01 00:00:00
abstract::The aim of this study was to evaluate the role of MR imaging of the fetus to improve sonographic prenatal diagnosis of congenital anomalies. In 40 fetuses (not consecutive cases) with an abnormality diagnosed with ultrasound, additional MR imaging was performed. The basic sequence was a T2-weighted single-shot half Fo...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1811-6
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVES:Assessment of empirical diffusion-weighted MRI (DW-MRI) models in cervical tumours to investigate whether fitted parameters distinguish between types and grades of tumours. METHODS:Forty-two patients (24 squamous cell carcinomas, 14 well/moderately differentiated, 10 poorly differentiated; 15 adenocarcinoma...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4417-0
更新日期:2017-02-01 00:00:00
abstract::The aim of this study was to depict and characterize inflammatory soft tissue proliferations caused by rheumatoid arthritis (RA) in the craniocervical region by unenhanced and contrast-enhanced CT. Computed tomography of the craniocervical region was performed in 35 patients in the axial plane before and after the i.v...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000433
更新日期:2000-01-01 00:00:00