Dendrimers: properties and applications.

abstract：:The map of candidate genes that can potentially affect physical fitness becomes larger every year, and they are associated with such aspects as respiratory and cardiovascular stability; body build and composition - especially muscle mass and strength; carbohydrate and lipid metabolism; response to training; and exerci...

journal_title：Acta biochimica Polonica

authors： Karpowicz K,Krych K,Karpowicz M,Nowak W,Gronek P

更新日期：2018-01-01 00:00:00

abstract：:Advanced oxidation protein products (AOPPs) are protein markers of oxidative stress with pro-inflammatory properties that accumulated in liver cirrhosis. In the present study, we investigated the association between chronic inflammatory response triggered by AOPPs and the severity of liver disease as assessed by the C...

journal_title：Acta biochimica Polonica

authors： Zuwała-Jagiełło J,Pazgan-Simon M,Simon K,Warwas M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Recent studies showed that sushi repeat containing protein X linked 2 (SRPX2) could participate in the development of various malignant tumors. However, its role in non-small cell lung cancer (NSCLC) was unknown. The aim of the study was to prospectively investigate the role of SRPX2 in NSCLC cell proliferat...

journal_title：Acta biochimica Polonica

authors： Li X,Liu J,Sun H,Zou Y,Chen J,Chen Y,Chen C,Wu X

更新日期：2020-06-18 00:00:00

abstract：:Initiation of replication of lambda DNA requires assembly of the proper nucleoprotein complex consisting of the lambda origin of replication-lambda O-lambda P-dnaB proteins. The dnaJ, dnaK and grpE heat shock proteins destabilize the lambda P-dnaB interaction in this complex permitting dnaB helicase to unwind lambda D...

journal_title：Acta biochimica Polonica

authors： Osipiuk J,Zylicz M

更新日期：1991-01-01 00:00:00

abstract：:Pharmaceutical substances and their residues are increasingly present in the environment. Therefore, attempts at their removal are made by using different processes. Increasingly important among these processes are those modeled on natural phenomena which occur in wetland ecosystems, called technical scale constructed...

journal_title：Acta biochimica Polonica

authors： Nowrotek M,Ziembińska-Buczyńska A,Miksch K

更新日期：2015-01-01 00:00:00

abstract：:Two different molecular forms of bacteriolytic endo-N-acetylmuramidase (EC 3.2.1.17) were found in the Acanthamoeba castellanii culture. The enzymes were separated by column chromatography on DEAE-Sephadex or by polyacrylamide-gel electrophoresis. In young cultures only one molecular form of the enzyme was selectively...

journal_title：Acta biochimica Polonica

authors： Drozański W

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Tunneled catheters are becoming increasingly used as a permanent dialysis access. Easy way of insertion and good long-term patency make them competitive to fistulas in some groups of patients. METHODS:Late complications and survival of 180 tunneled catheters inserted from June 2010 to December 2013 in 171 u...

journal_title：Acta biochimica Polonica

authors： Weber E,Liberek T,Wołyniec W,Gruszecki M,Rutkowski B

更新日期：2016-01-01 00:00:00

abstract：:The reaction of nitrite (NO2-) with horseradish peroxidase and lactoperoxidase was studied. Sequential mixing stopped-flow measurements gave the following values for the rate constants of the reaction of nitrite with compounds II (oxoferryl heme intermediates) of horseradish peroxidase and lactoperoxidase at pH 7.0, 1...

journal_title：Acta biochimica Polonica

authors： Gebicka L

更新日期：1999-01-01 00:00:00

abstract：:Polymorphisms in mitochondrial DNA (mtDNA) were analyzed in 152 samples from the Polish population using restriction enzymes AvaI, BamHI, HaeII, HpaI and PstI. Additionally, each sample was classified into the appropriate haplogroup. When required, appropriate fragments were sequenced to establish the exact polymorphi...

journal_title：Acta biochimica Polonica

authors： Piechota J,Tońska K,Nowak M,Kabzińska D,Lorenc A,Bartnik E

更新日期：2004-01-01 00:00:00

abstract：:To downregulate expression of the beta1 integrin subunit in endothelial cells, plasmid encoding the ribozyme cassette containing hammerhead ribozyme flanked at the 5' terminus by tRNA(Val) and at the 3' terminus by constitutive transport element sequences was constructed. When used to transfect immortalized human endo...

journal_title：Acta biochimica Polonica

authors： Papiewska-Pajak I,Antoszczyk S

更新日期：2006-01-01 00:00:00

abstract：:Two recently synthesized groups of acridine cytostatics containing fused heterocyclic ring(s): pyrazoloacridines (PAC) and pyrazolopyrimidoacridines (PPAC) were tested in regard to their in vitro cytotoxic activity towards a panel of sensitive and resistant human tumor cell lines. The obtained results corroborate our ...

journal_title：Acta biochimica Polonica

authors： Bontemps-Gracz MM,Kupiec A,Antonini I,Borowski E

更新日期：2002-01-01 00:00:00

abstract：:A number of antiviral lectins, small proteins that bind carbohydrates found on viral envelopes, are currently in pre-clinical trials as potential drugs for prevention of transmission of human immunodeficiency virus (HIV) and other enveloped viruses, such as the Ebola virus and the coronavirus responsible for severe ac...

journal_title：Acta biochimica Polonica

authors： Ziółkowska NE,Wlodawer A

更新日期：2006-01-01 00:00:00

abstract：:Temporin A (TA) and a cecropin A-temporin A hybrid peptide (CATA) were synthesized and assayed for their hemolytic, anticoagulant, and antifungal properties. CATA retains significant antifungal activity, is less hemolytic than TA, and inhibits blood coagulation. These results recommend further studies of the biologica...

journal_title：Acta biochimica Polonica

authors： Wade D,Silveira A,Rollins-Smith L,Bergman T,Silberring J,Lankinen H

更新日期：2001-01-01 00:00:00

abstract：:Genotoxic activities of flavonoids (quercetin, rhamnetin, isorhamnetin, apigenin, luteolin) were investigated using two short-term bacterial assays. In the "repair test" in Salmonella typhimurium (strains TA1538 uvrB- and TA1978 uvrB+) the flavonoids studied did not introduce any damage into the DNA recognized by UvrA...

journal_title：Acta biochimica Polonica

authors： Czeczot H,Kusztelak J

更新日期：1993-01-01 00:00:00

abstract：:The aim of the study presented here was an attempt to answer the question posed in the title: Is the mechanism of nitroglycerin tolerance associated with aldehyde dehydrogenase (ALDH) activity? Here, we investigated the effect of administration (separately or jointly) of lipoic acid (LA), nitroglycerin (GTN), and disu...

journal_title：Acta biochimica Polonica

authors： Bilska-Wilkosz A,Kotańska M,Górny M,Filipek B,Iciek M

更新日期：2019-12-28 00:00:00

abstract：:Nano- and microemulsions containing as the oil phase caprylic/capric propylene glycol diesters (Crodamol PC) were investigated as potential vehicle for controlled release of geranic acid. The influence of emulsifiers and co-surfactants on stability of the emulsions was investigated. Different kind of polysorbates (eth...

journal_title：Acta biochimica Polonica

authors： Jaworska M,Sikora E,Ogonowski J,Konieczna M

更新日期：2015-01-01 00:00:00

abstract：:Nowadays, scientists may learn a lot about the organisms studied just by analyzing their genetic material. This requires the development of methods of reading genomes with high accuracy. It has become clear that the knowledge of the changes occurring within a viral genome is indispensable for effective fighting of the...

journal_title：Acta biochimica Polonica

authors： Błazewicz J,Figlerowicz M,Formanowicz P,Kasprzak M,Nowierski B,Styszyński R,Szajkowski L,Widera P,Wiktorczyk M

更新日期：2004-01-01 00:00:00

abstract：:The mammalian deoxyribonucleoside kinases thymidine kinase 1 and 2, deoxycytidine kinase and deoxyguanosine kinase phosphorylate deoxyribonucleosides and provide an alternative to de novo synthesis of DNA precursors. Their activities are essential for activation of several chemotherapeutically important nucleoside ana...

journal_title：Acta biochimica Polonica

authors： Johansson NG,Eriksson S

更新日期：1996-01-01 00:00:00

abstract：:Infectious transcripts play a key role in the research on plant viruses at the molecular level. A number of cDNA clones covering the whole genome of the Polish isolate of potato leafroll virus were constructed. Four overlapping clones were selected and assembled using restriction sites. The full copy was positioned be...

journal_title：Acta biochimica Polonica

authors： Sadowy E,Pluta K,Gronenborn B,Hulanicka D

更新日期：1998-01-01 00:00:00

abstract：:Diabetes is one of the major challenges of modern medicine, as it is considered a global epidemic of the XXI century. The disease often leads to the development of serious, health threatening complications. Diabetic foot syndrome is a characteristic set of anatomical and molecular changes. At the macroscopic level, ma...

journal_title：Acta biochimica Polonica

authors： Bruhn-Olszewska B,Korzon-Burakowska A,Gabig-Cimińska M,Olszewski P,Węgrzyn A,Jakóbkiewicz-Banecka J

更新日期：2012-01-01 00:00:00

abstract：:Leukemia is a particular type of cancer characterized by the failure of cell death or disability in differentiation of hematopoietic cells. Chronic myelogenus leukemia (CML) is the most studied kind of this cancer. In this study, anti-cancer effect of dihydro-pyranochromenes derivatives were investigated in the human ...

journal_title：Acta biochimica Polonica

authors： Rahimi R,Mahdavi M,Pejman S,Zare P,Balalaei S

更新日期：2015-01-01 00:00:00

abstract：:Signalling concerns the transfer of information from one body, a source, to another, a receiver in order to stimulate activity. The problem arises with the word information. It is defined as what is transferred in a sequence of things, say between people, e.g. words or signs. The idea of signalling between people is t...

journal_title：Acta biochimica Polonica

authors： Williams RJ

更新日期：2004-01-01 00:00:00

abstract：:This brief resume enumerates the multiple actions of melatonin as an antioxidant. This indoleamine is produced in the vertebrate pineal gland, the retina and possibly some other organs. Additionally, however, it is found in invertebrates, bacteria, unicellular organisms as well as in plants, all of which do not have a...

journal_title：Acta biochimica Polonica

authors： Reiter RJ,Tan DX,Mayo JC,Sainz RM,Leon J,Czarnocki Z

更新日期：2003-01-01 00:00:00

abstract：:Aberrant expression of sialic acids or altered linkage types is closely associated with malignant phenotype and metastatic potential, and can have prognostic significance in human cancer. The present study was undertaken to evaluate whether expression of sialylated derivatives on melanoma cell surface is associated wi...

journal_title：Acta biochimica Polonica

authors： Kolasińska E,Przybyło M,Janik M,Lityńska A

更新日期：2016-01-01 00:00:00

abstract：:Patients with colorectal carcinoma showed statistically significant lower values of transferrin saturation, total iron binding capacity and serum iron level as compared with control group, while the level of ferritin and the size of labile iron pool in carcinoma patients were higher, although this difference was not s...

journal_title：Acta biochimica Polonica

authors： Gackowski D,Kruszewsk M,Banaszkiewicz Z,Jawien A,Olinski R

更新日期：2002-01-01 00:00:00

abstract：:Recent reports indicate that minichromosomes and other small genetic entities may occur in the nuclei of uninfected higher plants. They become especially abundant under some special growth conditions and, sometimes, resemble extrachromosomal genes of ciliated protozoa. An example of such gene-sized DNA species was iso...

journal_title：Acta biochimica Polonica

authors： Buchowicz J

更新日期：1997-01-01 00:00:00

abstract：:Glycosylation is the most common chemical process of protein modification and occurs in every living cell. Disturbances of this process may be either congenital or acquired. Congenital disorders of glycosylation (CDG) are a rapidly growing disease family, with about 50 disorders reported since its first clinical descr...

journal_title：Acta biochimica Polonica

authors： Cylwik B,Naklicki M,Chrostek L,Gruszewska E

更新日期：2013-01-01 00:00:00

abstract：:The VEGF family members are important factors in promoting angiogenesis and lymphangiogenesis in malignant processes. The aim of this study was to investigate plasma concentrations of VEGF-A, VEGF-B and their soluble VEGFR-1 receptor and their diagnostic utility and potency as compared to CA 15-3 in breast cancer pati...

journal_title：Acta biochimica Polonica

authors： Zajkowska M,Lubowicka E,Malinowski P,Szmitkowski M,Ławicki S

更新日期：2018-12-13 00:00:00

abstract：:Computer modelling related to the real dimensions of both the whole filament and the myosin molecule subfragments has revealed two alternative modes for myosin molecule packing which lead to the head disposition similar to that observed by EM on the surface of the cross-bridge zone of the relaxed vertebrate skeletal m...

journal_title：Acta biochimica Polonica

authors： Skubiszak L,Kowalczyk L

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Juvenile idiopathic arthritis (JIA) is a chronic, heterogenous inflammatory disease of unclear pathogenesis. JIA is hypothesized to be linked to a defective immune regulation. Anti-inflammatory cytokines belong to the best known regulatory factors. T-regulatory cells are a crucial cellular component of immun...

journal_title：Acta biochimica Polonica

authors： Sznurkowska K,Boćkowska M,Zieliński M,Plata-Nazar K,Trzonkowski P,Liberek A,Kamińska B,Szlagatys-Sidorkiewicz A

更新日期：2018-01-01 00:00:00