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Molecules on the surface of the Plasmodium falciparum infected erythrocyte and their role in malaria pathogenesis and immune evasion.

Abstract：

:The surface of the erythrocyte undergoes a number of modifications during infection by Plasmodium falciparum. These modifications are critical for pathogenesis of severe disease and the acquisition of host immunity through their role in interactions between the host and the parasite and in antigenic variation. Our knowledge of the molecular basis for these processes has increased dramatically over the last few years, through a combination of genomic and biochemical studies. This review provides a summary of the molecules involved in cytoadherence and antigenic variation in P. falciparum.

journal_name

Mol Biochem Parasitol

journal_title

Molecular and biochemical parasitology

authors

Craig A,Scherf A

doi

10.1016/s0166-6851(01)00275-4

subject

Has Abstract

pub_date

2001-07-01 00:00:00

pages

129-43

issue

2

eissn

0166-6851

issn

1872-9428

pii

S0166-6851(01)00275-4

journal_volume

115

pub_type

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