Effects of mean firing on neural information rate.

abstract：:We consider whole-cell voltage-clamp data of isolated currents characterized by the Hodgkin-Huxley paradigm. We examine the errors associated with the typical parameter estimation method for these data and show them to be unsatisfactorally large especially if the time constants of activation and inactivation are not s...

journal_title：Journal of computational neuroscience

authors： Willms AR,Baro DJ,Harris-Warrick RM,Guckenheimer J

更新日期：1999-03-01 00:00:00

abstract：:In the mammalian retina, complementary ON and OFF visual streams are formed at the bipolar cell dendrites, then carried to amacrine and ganglion cells via nonlinear excitatory synapses from bipolar cells. Bipolar, amacrine and ganglion cells also receive a nonlinear inhibitory input from amacrine cells. The most commo...

journal_title：Journal of computational neuroscience

authors： Molnar A,Hsueh HA,Roska B,Werblin FS

更新日期：2009-12-01 00:00:00

abstract：:This paper presents a synergistic parametric and non-parametric modeling study of short-term plasticity (STP) in the Schaffer collateral to hippocampal CA1 pyramidal neuron (SC) synapse. Parametric models in the form of sets of differential and algebraic equations have been proposed on the basis of the current underst...

journal_title：Journal of computational neuroscience

authors： Song D,Wang Z,Marmarelis VZ,Berger TW

更新日期：2009-02-01 00:00:00

abstract：:A number of tests exist to check for statistical significance of phase synchronisation within the Electroencephalogram (EEG); however, the majority suffer from a lack of generality and applicability. They may also fail to account for temporal dynamics in the phase synchronisation, regarding synchronisation as a consta...

journal_title：Journal of computational neuroscience

authors： Daly I,Sweeney-Reed CM,Nasuto SJ

更新日期：2013-06-01 00:00:00

abstract：:Deep brain stimulation (DBS) of the subthlamic nucleus (STN) represents an effective treatment for medically refractory Parkinson's disease; however, understanding of its effects on basal ganglia network activity remains limited. We constructed a computational model of the subthalamopallidal network, trained it to fit...

journal_title：Journal of computational neuroscience

authors： Hahn PJ,McIntyre CC

更新日期：2010-06-01 00:00:00

abstract：:The extraction of the direction of motion from the time varying retinal images is one of the most basic tasks any visual system is confronted with. However, retinal images are severely corrupted by photon noise, in particular at low light levels, thus limiting the performance of motion detection mechanisms of what sor...

journal_title：Journal of computational neuroscience

authors： Shi L,Borst A

更新日期：2006-04-01 00:00:00

abstract：:The calcium calmodulin dependent kinase (CaMKII) is important for long-term potentiation at dendritic spines. Photo-activatable GFP (PaGFP) - CaMKII fusions were used to map CaMKII movements between and within spines in dissociated hippocampal neurons. Photo-activated PaGFP (GFP*) generated in the shaft spread uniform...

journal_title：Journal of computational neuroscience

authors： Khan S,Reese TS,Rajpoot N,Shabbir A

更新日期：2012-08-01 00:00:00

abstract：:Linear additivity of synaptic input is a pervasive assumption in computational neuroscience, and previously Bernander et al. (Journal of Neurophysiology 72:2743-2753, 1994) point out that the sublinear additivity of a passive neuronal model can be linearized with voltage-dependent currents. Here we re-examine this per...

journal_title：Journal of computational neuroscience

authors： Morel D,Levy W

更新日期：2009-10-01 00:00:00

abstract：:We have previously formulated an abstract dynamical system for networks of spiking neurons and derived a formal result that identifies the criterion for its dynamics, without inputs, to be "sensitive to initial conditions". Since formal results are applicable only to the extent to which their assumptions are valid, we...

journal_title：Journal of computational neuroscience

authors： Banerjee A

更新日期：2006-06-01 00:00:00

abstract：:Synaptic plasticity is believed to represent the neural correlate of mammalian learning and memory function. It has been demonstrated that changes in synaptic conductance can be induced by approximately synchronous pairings of pre- and post- synaptic action potentials delivered at low frequencies. It has also been est...

journal_title：Journal of computational neuroscience

authors： Bush D,Jin Y

更新日期：2012-12-01 00:00:00

abstract：:Rhythmic bursting activity, found in many biological systems, serves a variety of important functions. Such activity is composed of episodes, or bursts (the active phase, AP) that are separated by quiescent periods (the silent phase, SP). Here, we use mean field, firing rate models of excitatory neural network activit...

journal_title：Journal of computational neuroscience

authors： Tabak J,O'Donovan MJ,Rinzel J

更新日期：2006-12-01 00:00:00

abstract：:Nonlinear dynamics provides a complementary framework to control theory for the quantitative analysis of the oculomotor control system. This paper presents a number of findings relating to the aetiology and mechanics of the pathological ocular oscillation jerk congenital nystagmus (jerk CN). A range of time series ana...

journal_title：Journal of computational neuroscience

authors： Akman OE,Broomhead DS,Clement RA,Abadi RV

更新日期：2006-10-01 00:00:00

abstract：:A critical component of any statistical modeling procedure is the ability to assess the goodness-of-fit between a model and observed data. For spike train models of individual neurons, many goodness-of-fit measures rely on the time-rescaling theorem and assess model quality using rescaled spike times. Recently, there ...

journal_title：Journal of computational neuroscience

authors： Tao L,Weber KE,Arai K,Eden UT

更新日期：2018-10-01 00:00:00

abstract：:Computational modeling of dendritic morphology is a powerful tool for quantitatively describing complex geometrical relationships, uncovering principles of dendritic development, and synthesizing virtual neurons to systematically investigate cellular biophysics and network dynamics. A feature common to many morphologi...

journal_title：Journal of computational neuroscience

authors： Donohue DE,Ascoli GA

更新日期：2005-10-01 00:00:00

abstract：:Characterizing how different cortical rhythms interact and how their interaction changes with sensory stimulation is important to gather insights into how these rhythms are generated and what sensory function they may play. Concepts from information theory, such as Transfer Entropy (TE), offer principled ways to quant...

journal_title：Journal of computational neuroscience

authors： Besserve M,Schölkopf B,Logothetis NK,Panzeri S

更新日期：2010-12-01 00:00:00

abstract：:Most neurons in the primary visual cortex initially respond vigorously when a preferred stimulus is presented, but adapt as stimulation continues. The functional consequences of adaptation are unclear. Typically a reduction of firing rate would reduce single neuron accuracy as less spikes are available for decoding, b...

journal_title：Journal of computational neuroscience

authors： Cortes JM,Marinazzo D,Series P,Oram MW,Sejnowski TJ,van Rossum MC

更新日期：2012-06-01 00:00:00

abstract：:Information transfer may not be limited only to synapses. Therefore, the processes and dynamics of biological neuron-astrocyte coupling and intercellular interaction within this domain are worth investigating. Existing models of tripartite synapse consider an astrocyte as a point process. Here, we extended the tripart...

journal_title：Journal of computational neuroscience

authors： Lorenzo J,Vuillaume R,Binczak S,Jacquir S

更新日期：2020-02-01 00:00:00

abstract：:Models of electrical activity in excitable cells involve nonlinear interactions between many ionic currents. Changing parameters in these models can produce a variety of activity patterns with sometimes unexpected effects. Further more, introducing new currents will have different effects depending on the initial para...

journal_title：Journal of computational neuroscience

authors： Fletcher P,Bertram R,Tabak J

更新日期：2016-06-01 00:00:00

abstract：:Simultaneous recordings of spike trains from multiple single neurons are becoming commonplace. Understanding the interaction patterns among these spike trains remains a key research area. A question of interest is the evaluation of information flow between neurons through the analysis of whether one spike train exerts...

journal_title：Journal of computational neuroscience

authors： Nedungadi AG,Rangarajan G,Jain N,Ding M

更新日期：2009-08-01 00:00:00

abstract：:The paper presents a hierarchical series of computational models for myelinated axonal compartments. Three classes of models are considered, either with distributed parameters (2.5D EQS-ElectroQuasi Static, 1D TL-Transmission Lines) or with lumped parameters (0D). They are systematically analyzed with both analytical ...

journal_title：Journal of computational neuroscience

authors： Ioan D,Bărbulescu R,Silveira LM,Ciuprina G

更新日期：2019-12-01 00:00:00

abstract：:One of the most common examples of audiovisual speech integration is the McGurk effect. As an example, an auditory syllable /ba/ recorded over incongruent lip movements that produce "ga" typically causes listeners to hear "da". This report hypothesizes reasons why certain clinical and listeners who are hard of hearing...

journal_title：Journal of computational neuroscience

authors： Altieri N,Yang CT

更新日期：2016-10-01 00:00:00

abstract：:This work presents a probabilistic method for inferring the parameter ranges in a biologically relevant mathematical model of the cortex most likely to be producing seizures observed in an electrocorticogram (ECoG) signal from a human subject. Additionally, this method produces a probabilistic pathway of the temporal ...

journal_title：Journal of computational neuroscience

authors： Dadok VM,Kirsch HE,Sleigh JW,Lopour BA,Szeri AJ

更新日期：2015-06-01 00:00:00

abstract：:Can one develop an abstract description of the dynamics of pattern generators that provides quantitative insight into their operation? We explored this question by examining the dynamics of a model central pattern generator that was created using an evolutionary algorithm. We propose an abstract description based on t...

journal_title：Journal of computational neuroscience

authors： Chiel HJ,Beer RD,Gallagher JC

更新日期：1999-09-01 00:00:00

abstract：:We investigate the use of extracellular action potential (EAP) recordings for biophysically faithful compartmental models. We ask whether constraining a model to fit the EAP is superior to matching the intracellular action potential (IAP). In agreement with previous studies, we find that the IAP method under-constrain...

journal_title：Journal of computational neuroscience

authors： Gold C,Henze DA,Koch C

更新日期：2007-08-01 00:00:00

abstract：:Calmodulin (CaM) is a major Ca(2+) binding protein involved in two opposing processes of synaptic plasticity of CA1 pyramidal neurons: long-term potentiation (LTP) and depression (LTD). The N- and C-terminal lobes of CaM bind to its target separately but cooperatively and introduce complex dynamics that cannot be well...

journal_title：Journal of computational neuroscience

authors： Byrne MJ,Putkey JA,Waxham MN,Kubota Y

更新日期：2009-12-01 00:00:00

abstract：:Motivated by experimental observations of the head direction system, we study a three population network model that operates as a continuous attractor network. This network is able to store in a short-term memory an angular variable (the head direction) as a spatial profile of activity across neurons in the absence of...

journal_title：Journal of computational neuroscience

authors： Boucheny C,Brunel N,Arleo A

更新日期：2005-03-01 00:00:00

abstract：:The phase relationship between the activity of hippocampal place cells and the hippocampal theta rhythm systematically processes as the animal runs through the region in an environment called the place field of the cell. We present a minimal biophysical model of the phase precession of place cells in region CA3 of the...

journal_title：Journal of computational neuroscience

authors： Bose A,Booth V,Recce M

更新日期：2000-07-01 00:00:00

abstract：:Firing-rate models provide a practical tool for studying signal processing in the early visual system, permitting more thorough mathematical analysis than spike-based models. We show here that essential response properties of relay cells in the lateral geniculate nucleus (LGN) can be captured by surprisingly simple fi...

journal_title：Journal of computational neuroscience

authors： Heiberg T,Kriener B,Tetzlaff T,Casti A,Einevoll GT,Plesser HE

更新日期：2013-12-01 00:00:00

abstract：:Hebbian plasticity means that if the firing of two neurons is correlated, then their connection is strengthened. Conversely, uncorrelated firing causes a decrease in synaptic strength. Spike-timing-dependent plasticity (STDP) represents one instantiation of Hebbian plasticity. Under STDP, synaptic changes depend on th...

journal_title：Journal of computational neuroscience

authors： Houben AM,Keil MS

更新日期：2020-02-01 00:00:00

abstract：:A neuron's firing correlates are defined as the features of the external world to which its activity is correlated. In many parts of the brain, neurons have quite simple such firing correlates. A striking example are grid cells in the rodent medial entorhinal cortex: their activity correlates with the animal's positio...

journal_title：Journal of computational neuroscience

authors： Rosay S,Weber S,Mulas M

更新日期：2019-08-01 00:00:00