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Regiospecific synthesis of 2,3-disubstituted-L-histidines and histamines.

Abstract：

:Regiospecific synthesis of 2,3-disubstituted-L-histidines and 2,3-disubstituted histamines starting from L-histidine methyl ester and histamine is reported. The key step involves homolytic free radical alkylation via silver catalyzed oxidative decarboxylation of alkylcarboxylic acids with ammonium persulfate.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Narayanan S,Vangapandu S,Jain R

doi

10.1016/s0960-894x(01)00154-8

subject

Has Abstract

pub_date

2001-05-07 00:00:00

pages

1133-6

issue

9

eissn

0960-894X

issn

1464-3405

pii

S0960894X01001548

journal_volume

11

pub_type

杂志文章

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