Abstract:
:Sphingosine-1-phosphate (S1P) is considered to be an important regulator of diverse biological processes acting as a natural ligand to EDG receptors. As a preliminary study to develop potent and selective agonist and antagonist for EDG receptors, we report synthesis of S1P stereoisomers and analogues and their binding affinities to EDG-1, -3, and -5.
journal_name
Bioorg Med Chem Lettjournal_title
Bioorganic & medicinal chemistry lettersauthors
Lim HS,Oh YS,Suh PG,Chung SKdoi
10.1016/s0960-894x(02)00893-4subject
Has Abstractpub_date
2003-01-20 00:00:00pages
237-40issue
2eissn
0960-894Xissn
1464-3405pii
S0960894X02008934journal_volume
13pub_type
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