Abstract:
OBJECTIVES:To describe the small area system developed in Finland. To illustrate the use of the system with analyses of incidence of lung cancer around an asbestos mine. To compare the performance of different spatial statistical models when applied to sparse data. METHODS:In the small area system, cancer and population data are available by sex, age, and socioeconomic status in adjacent "pixels", squares of size 0.5 km x 0.5 km. The study area was partitioned into sub-areas based on estimated exposure. The original data at the pixel level were used in a spatial random field model. For comparison, standardised incidence ratios were estimated, and full bayesian and empirical bayesian models were fitted to aggregated data. Incidence of lung cancer around a former asbestos mine was used as an illustration. RESULTS:The spatial random field model, which has been used in former small area studies, did not converge with present fine resolution data. The number of neighbouring pixels used in smoothing had to be enlarged, and informative distributions for hyperparameters were used to stabilise the unobserved random field. The ordered spatial random field model gave lower estimates than the Poisson model. When one of the three effects of area were fixed, the model gave similar estimates with a narrower interval than the Poisson model. CONCLUSIONS:The use of fine resolution data and socioeconomic status as a means of controlling for confounding related to lifestyle is useful when estimating risk of cancer around point sources. However, better statistical methods are needed for spatial modelling of fine resolution data.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Kokki E,Ranta J,Penttinen A,Pukkala E,Pekkanen Jdoi
10.1136/oem.58.5.315subject
Has Abstractpub_date
2001-05-01 00:00:00pages
315-20issue
5eissn
1351-0711issn
1470-7926journal_volume
58pub_type
杂志文章abstract:OBJECTIVES:Molecular epidemiological techniques, capable of detecting damage to DNA, were used to see if such damage occurred in the lymphocytes of a group of workers exposed to chromium. The two aims of this pilot study were to see if these new techniques might make useful biological monitoring tools for workers expos...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.10.663
更新日期:1994-10-01 00:00:00
abstract:OBJECTIVE:To estimate the occurrence of hand eczema in hairdressers in Sweden. METHODS:The occurrence of hand eczema was estimated in a Swedish longitudinal retrospective cohort study including all female graduates from vocational schools for hairdressers from 1970 to 1995. A stratified sample from the general populat...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2005.026211
更新日期:2007-03-01 00:00:00
abstract:AIMS:To analyse the effects of age and occupational factors on both the incidence and the disappearance of chronic neck and shoulder pain after a five year follow up period. METHODS:A prospective longitudinal investigation (ESTEV) was carried out in 1990 and 1995 in seven regions of France. A random sample of male and...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.59.8.537
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVES:A previous study of the short term effects of air pollution in London from April 1987 to March 1992 found associations between all cause mortality and black smoke and ozone, but no clear evidence of specificity for cardiorespiratory deaths. London data from 1992 to 1994 were analysed to examine the consisten...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.4.237
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVES:Self-reported exposure to vapours, gas, dust or fumes (VGDF) has been widely used as an occupational exposure metric in epidemiological studies of chronic lung diseases. Our objective was to characterise the performance of VGDF for repeatability, systematic misclassification, and sensitivity and specificity ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2008.040022
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:To explore the healthy worker survivor effect (HWSE) in a study of Vermont granite workers by distinguishing "prevalent" from "incident" hires based on date of hire before or after the start of follow-up. METHODS:Records of workers between 1950 and 1982 were obtained from a medical surveillance programme. Pr...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2006.031369
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVES:The main objective of this study was to investigate exposure-response relations between adverse musculoskeletal outcomes and ergonomic exposure variables. METHODS:A cross sectional analytical study was conducted in 11 factories from seven sectors of manufacturing industry in South Africa. Exposure to workpl...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.1.46
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVES:While several studies have reported associations of daily exposures to PM2.5 (particles less than 2.5 µm) with mortality, few studies have examined the impact of its constituents such as black carbon (BC), which is also a significant contributor to global climate change. METHODS:We assessed the association ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2014-102184
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVES:There is an ongoing debate regarding environmental health risks of exposures to dust and microbial agents from livestock farming in the Netherlands. The aims of the study were (1) to investigate associations between indicators of air pollution from livestock farms and asthma, allergic rhinitis and chronic ob...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2013-101485
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:Due to recent changes in legislation on occupational health and safety, a national monitor on stress and physical load was developed in The Netherlands to monitor (a) risks and consequences of stress and physical load at work, (b) preventive actions in companies to reduce these risks, and (c) organisational ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.2.73
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVE:To assess whether the increased risk of disease related to asbestos in occupations from the construction and engineering industries applies equally to pleural cancer, peritoneal cancer, and asbestosis. METHODS:Analysis was based on deaths among men aged 20-74 in England and Wales during 1979-80 and 1982-90. ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.11.775
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVES:To investigate the occurrence of work related respiratory symptoms and to assess the effect of atopy in a group of trainee bakers. METHODS:A prospective study of work related respiratory symptoms among 125 trainee bakers who were investigated with a questionnaire plus skin prick test with wheat flour and al...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.57.1.58
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:Job exposure matrices (JEMs) can be constructed from expert-rated assessments, direct measurement and self-reports. This paper describes the construction of a general population JEM based on self-reported physical exposures, its ability to create homogeneous exposure groups (HEG) and the use of different exp...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2018-105287
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVES:The current study examines and compares the relationship between both macroeconomic and industry-specific business cycle indicators, and work-related injuries among construction workers in Denmark using emergency department (ED) injury data and also officially reported injuries to the Danish Working Environm...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2014-102290
更新日期:2015-04-01 00:00:00
abstract:AIMS:To investigate the effects of smoking and personal hygienic behaviour on blood lead (BPb) and free erythrocyte protoporphyrin levels (FEP) in lead exposed workers. METHODS:Subjects were 105 lead exposed male workers in a battery recycling plant during the years 2000-03. BPb and FEP were measured as part of the on...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.019513
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVES:To review and summarise the epidemiological evidence on the carcinogenicity of occupational exposure to inorganic lead. METHODS:Case-control and cohort studies were reviewed and combined for meta-analysis. Fixed and random effect methods were used to estimate the summary effects. RESULTS:The combined resul...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析
doi:10.1136/oem.52.2.73
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:Serious delayed neuropsychological sequelae may complicate carbon monoxide intoxication. The existence of minor manifestations, especially memory disturbances, is not well documented. AIMS:To study several memory functions after carbon monoxide intoxication. METHODS:In a prospective study, 32 poisoned pati...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.3.212
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVES:The main objective was to study the acute vascular effects in the hands of normal healthy subjects of a complex vibration spectrum similar to that generated by many industrial hand held tools. The effects of repeated bouts of vibrations and alterations in the intensity of vibration were also studied. METHOD...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.10.663
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVE:This study was undertaken to assess whether contaminated personal clothing worn beneath a coverall (normal workwear) is a source of potentially significant dermal exposure to polycyclic aromatic hydrocarbons (PAHs) in coal liquefaction workers. METHODS:An intervention study was conducted over a two week peri...
journal_title:Occupational and environmental medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/oem.52.9.600
更新日期:1995-09-01 00:00:00
abstract::Dermal uptake of chemicals at the workplace may contribute considerably to the total internal exposure and so needs to be regulated. At present only qualitative warning signs--the "skin notations"--are available as instruments. An attempt was made to develop a quantitative dermal occupational exposure limit (DOEL) com...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.55.12.795
更新日期:1998-12-01 00:00:00
abstract:OBJECTIVES:Poisson regression is now widely used in epidemiology, but researchers do not always evaluate the potential for bias in this method when the data are overdispersed. This study used simulated data to evaluate sources of overdispersion in public health surveillance data and compare alternative statistical mode...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2008.042887
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVES:Structural impairment of the renal proximal tubular epithelium induced by cadmium (Cd) was investigated by measuring the concentration of neutral endopeptidase 24.11 (NEP), an ectoenzyme of the apical brush border, in the urine of 106 male workers employed in a Cd smelter (among whom 52 were occupationally e...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.6.432
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVES:The chronic effects of urban air pollution are not well known. The authors' aim was to investigate the association between the prevalence and new onset of chronic bronchitis and urban air pollution. METHODS:Subjects from the general population randomly selected for the European Community Respiratory Health ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2006.027995
更新日期:2006-12-01 00:00:00
abstract::Although the neurological and cardiovascular effects of Freons have been extensively described, the respiratory effects have been less well documented. We report four cases of occupational asthma following accidental exposure to bromochlorodifluoromethane (Halon 1211) due to release of the contents of a fire extinguis...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2003.009837
更新日期:2004-08-01 00:00:00
abstract:CONTEXT:More than 400,000 workers annually receive a measurable radiation dose and may be at increased risk of radiation-induced leukaemia. It is unclear whether leukaemia risk is elevated with protracted, low-dose exposure. OBJECTIVE:We conducted a meta-analysis examining the relationship between protracted low-dose ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1136/oem.2009.054684
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:The fit note, introduced in England, Wales and Scotland in 2010, was designed to change radically the sickness certification process from advising individuals on their inability to work to advising them on what they could do if work could be adapted. Our review aimed to evaluate the following: (1) Is the 'ma...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2017-104730
更新日期:2018-07-01 00:00:00
abstract:AIMS:To correlate the prevalence of respiratory tract symptoms and diseases with dust and fibre exposure in the soft tissue industry in Germany. METHODS:Ambient monitoring was performed for inhalable, respirable dust and fibres in seven soft tissue producing factories. In 441 workers (72 controls, 90 moderate, 279 hig...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.59.12.830
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVES:To investigate the relation with a case-control study between symptomatic osteochondrosis or spondylosis of the lumbar spine and cumulative occupational exposure to lifting or carrying and to working postures with extreme forward bending. METHODS:From two practices and four clinics were recruited 229 male p...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.58.11.735
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVES:To investigate the association between preeclampsia and maternal exposure to ambient particulate matter (PM) with aerodynamic diameter less than 10 μm (PM10) and 2.5 μm (PM2.5) mass and sources. METHODS:Our analysis was based on a hospital cohort of pregnant women (N=3182) residing in Barcelona, Spain, duri...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2013-101693
更新日期:2014-08-01 00:00:00
abstract:AIMS:To investigate whether exposure to cobalt in cobalt plants has any measurable effect on the cardiovascular system. METHODS:Occupational, cross sectional study, using a self administered questionnaire, blood pressure measurement, electrocardiography, and laboratory tests in which 203 male workers with at least one...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2003.009605
更新日期:2004-11-01 00:00:00