Randomized, double-blind, placebo-controlled, multicenter study of sibutramine in obese hypertensive patients.

abstract：AIM:The aim of this study was to determine whether on-line vectorcardiography (VCG) gives independent prognostic information, regarding death, myocardial infarction (MI), and revascularization in patients with unstable coronary artery disease, i.e. unstable angina or non-Q-wave MI. METHODS AND RESULTS:One hundred and ...

journal_title：Cardiology

authors： Lundin P,Jensen J,Lindahl B,Wallentin L,Eriksson SV

更新日期：2000-01-01 00:00:00

abstract：:Cell membrane phospholipids, including platelet-activating factor (PAF), participate in the pathogenesis of acute myocardial infarction (AMI). The plasma level of PAF acetylhydrolase (AH) was determined in 18 patients at presentation with AMI before thrombolysis, and the administration of adjunctive therapy, and compa...

journal_title：Cardiology

authors： Serebruany VL,Gurbel PA,Murugesan SR,Lowry DR,Sturm E,Svetlov SI

更新日期：1998-10-01 00:00:00

abstract：:Since the introduction of fenofibrate to European clinical practice in 1975, some 6.5 million patient-years of experience in the treatment of hyperlipidemia have been accumulated. A review of results of clinical trials shows fenofibrate to have a broad spectrum of lipid-lowering activity, reducing the total cholestero...

journal_title：Cardiology

authors： Blane GF

更新日期：1989-01-01 00:00:00

abstract：:Studies of heart rate and blood pressure responses to 70 degrees head-up tilt and 30 degrees head-down tilt were conducted in normal subjects and in chronic cardiac chagasic patients without past or present cardiac decompensation. During steady state of tilt, heart rate alterations were less marked in the chagasic tha...

journal_title：Cardiology

authors： Neto JA,Gallo L Jr,Manço JC,Rassi A,Amorim DS

更新日期：1975-01-01 00:00:00

abstract：:Fifty percent of patients with dilated cardiomyopathy die within 5 years of diagnosis. Syncope is known to be a predictor of poor outcome in patients with advanced heart failure. To assess the risk of patients with dilated cardiomyopathy with a history of syncope during standard medical treatment we compared this grou...

journal_title：Cardiology

authors： Fruhwald FM,Eber B,Schumacher M,Zweiker R,Watzinger N,Klein WW

更新日期：1996-05-01 00:00:00

abstract：:A laminar color Doppler flow was discovered in the pericardial space in a 35-year-old man with postpericardiotomy effusive constrictive pericarditis. The flow was detected by transesophageal color Doppler echocardiography. A further pulsed Doppler study revealed a to-and-fro flow, which was synchronized with the cardi...

journal_title：Cardiology

authors： Lai LP,Shyu KG,Chang CI,Ko YL,Kuan P,Lien WP

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:Four drug classes, platelet inhibitors, β-blockers, statins, and angiotensin-converting enzyme inhibitors (or angiotensin receptor blockers), have been shown to reduce mortality in clinical trials. We sought to evaluate whether the simple number of secondary prevention drugs at discharge is independently asso...

journal_title：Cardiology

authors： Kopel E,Klempfner R,Goldenberg I,Schwammenthal E

更新日期：2014-01-01 00:00:00

abstract：:Fractional flow reserve (FFR) may not be immune from hemodynamic perturbations caused by both vessel and lesion related factors. The aim of this study was to investigate the impact of plaque- and vessel wall-related features of vulnerability on the hemodynamic effect of intermediate coronary stenoses. Methods and Resu...

journal_title：Cardiology

authors： Sezer M,Aslanger E,Cakir O,Atici A,Sezer I,Ozcan A,Umman B,Bugra Z,Umman S

更新日期：2021-01-01 00:00:00

abstract：:To study the effects of steroid elution on chronic pacing threshold and impedance, a 4-mm2 surface area lead with steroid (030-368, Telectronics; n = 9) was compared to the same lead without steroid (030-359, Telectronics; n = 9) 3 months after implantation. The pulse duration thresholds of the steroid lead were signi...

journal_title：Cardiology

authors： Schuchert A,Kuck KH

更新日期：1993-01-01 00:00:00

abstract：:We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). T...

journal_title：Cardiology

authors： Lee SH,Ko YG,Jang Y,Kwon HM,Lee SH,Yoon JH,Park SH,Kim BO,Jeon DW,Yang JY,Ryu SK,Korean Multicenter Angioplasty Team (KOMATE) Investigators.

更新日期：2005-01-01 00:00:00

abstract：:The primary aim of the management of hypertension should be to prevent coronary heart disease. Antihypertensive treatment should have a beneficial effect on the risk factors associated with coronary heart disease, particularly hypertension, dyslipidemia, hyperinsulinemia, and/or glucose intolerance. Other important ri...

journal_title：Cardiology

authors： Weidmann P

更新日期：1994-01-01 00:00:00

abstract：:Over the last 30 years, several epidemiological and prospective studies have identified a number of risk factors for the development of cardiovascular disease. Lipid abnormalities are central among these risk factors, and their correction has been a major target for the medical community. The 3-hydroxy-3-methyl glutar...

journal_title：Cardiology

authors： Bruckert E

更新日期：2002-01-01 00:00:00

abstract：:Silent myocardial ischemia is a marker in patients with coronary artery disease identifying those at high risk for subsequent cardiac events. During provoked myocardial ischemia some patients with angina pectoris do not develop chest pain. Are there clinical, angiographic or electrocardiographic differences between pa...

journal_title：Cardiology

authors： Dellborg M,Emanuelsson H,Swedberg K

更新日期：1993-01-01 00:00:00

abstract：:Treatment of congestive heart failure has changed dramatically during the past 20 years, but diuretic drugs remain an essential component. Diuretics are essential despite the fact that these drugs stimulate the renin-angiotensin-aldosterone (RAA) axis and lead to adaptive responses that may be counterproductive. In th...

journal_title：Cardiology

authors： Ellison DH

更新日期：2001-01-01 00:00:00

abstract：:Atrial fibrillation is a complex disease. Its etiologies are diverse and genetic factors may also contribute to this disease. With the advent of modern molecular biology technology, it is now possible to explore the genetic components in the pathogenesis of atrial fibrillation. Past molecular genetic studies on atrial...

journal_title：Cardiology

authors： Lai LP,Lin JL,Huang SK

更新日期：2003-01-01 00:00:00

abstract：:A bicuspid aortic valve (BAV) is one of the most common congenital heart anomalies. Although each annuloaortic ectasia (AAE) and malformation of the left coronary artery has been described as a complication of BAV, no case associated with both abnormalities has been reported previously. We present here a very rare cas...

journal_title：Cardiology

authors： Takahashi M,Ikeda U,Shimada K,Takeda H

更新日期：1994-01-01 00:00:00

abstract：:Ventricular late potentials are obtained by signal averaging of surface electrocardiograms. Late potentials have been reported to be affected by body size or left ventricular mass. However, the effect of subadipose tissue, which is known to influence QRS amplitudes of surface ECG, on the variables of late potentials h...

journal_title：Cardiology

authors： Masui A,Tsuji H,Tamura K,Sugiura T,Matsui Y,Iwasaka T,Inada M

更新日期：1993-01-01 00:00:00

abstract：:Ventricular late potentials are obtained by signal-averaged surface electrocardiography. Late potentials have been reported to be affected by body characteristics or left ventricular mass. To evaluate late potentials in relation to body characteristics, 52 healthy Japanese young volunteers (21 girls, 31 boys) aged 15-...

journal_title：Cardiology

authors： Iwasaka T,Usui H,Masui A,Tamura K,Sugiura T,Karakawa M,Inada M

更新日期：1993-01-01 00:00:00

abstract：:We assessed the relation between baseline electrocardiographic ischemia grades and initial myocardial area at risk (AR) and final infarct size (IS) in 49 patients who had undergone (99m)Tc sestamibi single-photon emission computed tomography before and 6 +/- 1 days after thrombolysis. Patients were classed as having g...

journal_title：Cardiology

authors： Birnbaum Y,Mahaffey KW,Criger DA,Gates KB,Barbash GI,Barbagelata A,Clemmensen P,Sgarbossa EB,Gibbons RJ,Rahman MA,Califf RM,Granger CB,Wagner GS,AMISTAD (Acute Myocardial Infarction Study of Adenosine) Investigators.

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:β-Thalassemias are inherited hemolytic anemias with a broad phenotype and an increased rate of vascular complications despite a near absence of coronary artery disease. METHODS:We investigated the presence of endothelial dysfunction and subclinical atherosclerosis in non-transfusion-dependent patients with ...

journal_title：Cardiology

authors： Hahalis G,Kalogeropoulos A,Terzis G,Tselepis AD,Kourakli A,Mylona P,Grapsas N,Alexopoulos D

更新日期：2011-01-01 00:00:00

abstract：:Coronary arteries in diabetic patients appear to be narrower than in normal subjects, but this has not been examined systematically. To investigate this hypothesis we reviewed the data of 711 consecutive patients with angiographically 'normal coronary arteries'. Excluded were patients with valvular, myocardial or peri...

journal_title：Cardiology

authors： Mosseri M,Nahir M,Rozenman Y,Lotan C,Admon D,Raz I,Gotsman MS

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:Neuregulin receptor degradation protein-1 (Nrdp1) is a novel E3 ubiquitin ligase, and we have previously shown that overexpression of Nrdp1 increased cardiomyocyte injury. However, the role of Nrdp1 in myocardial hypertrophy is unclear. In the present study, we clarified the molecular mechanisms of angiotensi...

journal_title：Cardiology

authors： Zhang Y,Su L,Zhang K

更新日期：2016-01-01 00:00:00

abstract：:(1) 36 outpatients with a manifest orthostatic syndrome were the subject of a double-blind study to investigate the influence of Dihydergot and a placebo over a 4-week period. (2) In the majority of subjects, the dosage was 1 tablet (2.5 mg) 3 times a day. (3) In the test group with Dihydergot (17 subjects), a normali...

journal_title：Cardiology

authors： Lübke KO

更新日期：1976-01-01 00:00:00

abstract：:The acute effects of therapeutic doses of intravenous tolbutamide and glibornuride on the systolic time intervals (QS2c, LVETc, PEPc and PEP/LVET) were examined in 5 healthy volunteers. Blood sugar was maintained constant throughout the study. No significant changes of these intervals as well as of heart rate and bloo...

journal_title：Cardiology

authors： Dubach UC,Burckhardt D,Raeder EA,Forgo I,Amrein R,Bückert A

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:The purpose of the present study was to examine physician's attitudes and practices toward the use of different lipid-lowering management strategies in patients at increased risk for coronary heart disease (CHD). AIMS/METHODS:An internet-based questionnaire was completed by 78 general internists and family ...

journal_title：Cardiology

authors： Goldberg RJ,Rosen J,Roselli A,Lewis B

更新日期：2007-01-01 00:00:00

abstract：:To study the effect of coronary angioplasty (PTCA) on left ventricular (LV) diastolic filling, mitral Doppler flow tracings of 15 patients with isolated stenosis of the left anterior descending coronary artery (LAD) and normal systolic LV function were recorded before PTCA as well as 24 h and 3 months after successful...

journal_title：Cardiology

authors： Ricou F,Lerch R,Meier B,Rutishauser W

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:J-point elevation in the inferior and/or lateral leads is associated with an increased incidence of sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM), although the exact underlying mechanism is not known. As severe left ventricular hypertrophy and late gadolinium enhancement (LGE) are important...

journal_title：Cardiology

authors： Azevedo PMO,Guerreiro C,Ladeiras-Lopes R,Ferreira N,Faria R,Barbosa R,Primo J,Braga J

更新日期：2020-01-01 00:00:00

abstract：:Lipid-lowering agents are used with the purpose of ameliorating hyperlipoproteinemias, in order to prevent arterial disease. Lipid-lowering drugs can be classified into absorbable agents and into nonabsorbable compounds, acting within the gastrointestinal lumen. Absorbable drugs (fibric acids, nicotinic acid, probucol...

journal_title：Cardiology

authors： Sirtori CR,Manzoni C,Lovati MR

更新日期：1991-01-01 00:00:00

abstract：:Ticagrelor has been shown to be superior to clopidogrel in patients presenting with acute myocardial infarction who undergo early invasive treatment. We discuss a hitherto unreported use of ticagrelor in the management of a patient resistant to multiple thienopyridines at high risk of stent thrombosis. ...

journal_title：Cardiology

authors： Morgan KP,More RS,Chauhan A

更新日期：2011-01-01 00:00:00

abstract：:Physical training causes an increase of aerobic capacity in normal and cardiac patients. The influences of training plus placebo and training plus verapamil have been studied in a double-blind randomized trial on 40 patients recovering from actue myocardial infarction. The two groups were comparable as to clinical cha...

journal_title：Cardiology

authors： Rossi P,Giordano A,Tamiz A,Schiavo B,Minuco G

更新日期：1979-01-01 00:00:00