当前位置： SCI文献检索 > JOURNAL OF INORGANIC BIOCHEMISTRY期刊下所有文献 > Introduction of a specific binding domain on myoglobin surface by new chemical modification.

Introduction of a specific binding domain on myoglobin surface by new chemical modification.

Abstract：

:A new myoglobin, reconstituted with a modified zinc protoporphyrin, having a total of four ammonium groups at the terminal of the two propionate side chains was constructed to introduce a substrate binding site. The protein with a positively charged patch on the surface formed a stable complex with negatively charged substrates, such as hexacyanoferrate(III) and anthraquinonesulfonate via an electrostatic interaction. The complexation was monitored by fluorescence quenching due to singlet electron transfer from the photoexcited reconstituted zinc myoglobin to the substrates. The binding properties were evaluated by Stern-Volmer plots from the fluorescence quenching of the zinc myoglobin by a quencher. Particularly, anthraquinone-2,7-disulfonic acid showed a high affinity with a binding constant of 1.5 x 10(5) M(-1) in 10 mM phosphate buffer, pH 7.0. In contrast, the plots upon the addition of anthraquinone-2-sulfonic acid at different ionic strengths indicated that the complex was formed not only by an electrostatic interaction but also by a hydrophobic contact. The findings from the fluorescence studies conclude that the present system is a useful model for discussion of electron transfer via non-covalently linked donor-acceptor pairing on the protein surface.

journal_name

J Inorg Biochem

journal_title

Journal of inorganic biochemistry

authors

Hayashi T,Ando T,Matsuda T,Yonemura H,Yamada S,Hisaeda Y

doi

10.1016/s0162-0134(00)00153-7

subject

Has Abstract

pub_date

2000-11-01 00:00:00

pages

133-9

issue

1-4

eissn

0162-0134

issn

1873-3344

pii

S0162-0134(00)00153-7

journal_volume

82

pub_type

杂志文章

相关文献

JOURNAL OF INORGANIC BIOCHEMISTRY文献大全
  • Relationship between the antiproliferative properties of Cu(II) complexes with the Schiff base derived from pyridine-2-carboxaldehyde and 5,6-diamino-1,3-dimethyluracil and the redox status mediated by antioxidant defense systems on glioma tumoral cells.

    abstract：:A set of new copper(II) complexes containing the Schiff base ligand derived from pyridine-2-carboxaldehyde and 5,6-diamino-1,3-dimethyluracil (6-amino-1,3-dimethyl-5-[(pyridin-2-ylmethylidene)-amino]-pyrimidine-2,4(1H,3H)-dione) with several anions (Cl-, Br-, I-, ClO4-, NO3-) and, two of them with 1,10-phenanthroline,...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2020.111053

    authors： Illán-Cabeza NA,Jiménez-Pulido SB,Hueso-Ureña F,Ramírez-Expósito MJ,Martínez-Martos JM,Moreno-Carretero MN

    更新日期：2020-06-01 00:00:00

  • Ternary oxovanadium(IV) complexes with amino acid-Schiff base and polypyridyl derivatives: synthesis, characterization, and protein tyrosine phosphatase 1B inhibition.

    abstract：:To investigate the structure-activity relationship of vanadium complexes in inhibiting protein tyrosine phosphatase1B (PTP1B), eight mixed-ligand oxovanadium(IV) complexes, [V(IV)O(SalAla)(NN)] (H(2)SalAla for salicylidene alanine, NN for N,N'-donor heterocyclic base, namely, 2,2'-bipyridine (bpy, 1), 1,10-phenanthrol...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2011.07.008

    authors： Lu L,Yue J,Yuan C,Zhu M,Han H,Liu Z,Guo M

    更新日期：2011-10-01 00:00:00

  • Anti-adhesive action of novel ruthenium(II) chlorophenyl terpyridine complexes with a high affinity for double-stranded DNA: in vitro and in silico.

    abstract：:Interactions of three Ru(II) chlorophenyl terpyridine complexes: [Ru(Cl-Ph-tpy)(en)Cl]Cl (1), [Ru(Cl-Ph-tpy)(dach)Cl]Cl (2) and [Ru(Cl-Ph-tpy)(bpy)Cl]Cl (3) (Cl-Ph-tpy = 4'-(4-chlorophenyl)-2,2':6',2''-terpyridine, en = 1,2-diaminoethane, dach = 1,2-diaminocyclohexane, bpy = 2,2'-bipyridine) with human serum albumin (...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2020.111090

    authors： Masnikosa R,Milutinović MM,Crnolatac I,Tot A,Veličković S,Bojić-Trbojević Ž,Rilak-Simović A

    更新日期：2020-07-01 00:00:00

  • The reactivity of pulsed cytochrome c oxidase toward carbon monoxide.

    abstract：:When pulsed cytochrome c oxidase is exposed to carbon monoxide in the absence of oxygen the enzyme is converted quickly to its CO-associated mixed valence state. The half-time for this reaction at 0 degree C is about 4 min. This is about 100 times faster than a similar reaction which begins with the resting form of th...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(85)85038-8

    authors： Morgan JE,Blair DF,Chan SI

    更新日期：1985-03-01 00:00:00

  • Kinetic studies on the reaction between Trametes villosa laccase and dioxygen.

    abstract：:A laccase from the fungus Trametes villosa (TviL) was investigated in order to elucidate the reaction mechanism of the reduction of dioxygen to water performed by this blue multi-copper oxidase. The ability of TviL to activate dioxygen was studied by stopped-flow experiments and under steady-state conditions. In the s...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2006.05.007

    authors： Bukh C,Lund M,Bjerrum MJ

    更新日期：2006-09-01 00:00:00

  • Surface complex of ZnTMPyP4 metalloporphyrin with double-stranded Poly(A)-Poly(U).

    abstract：:This communication presents synthesis and spectral characterization of metalloporphyrin [Zn(X)TMPyP4] (TMPyP4 is 5,10,15,20-tetrakis (N-methylpyridinium-4-yl)porphyrin), and studies its binding onto anionic surface sites of synthetic double stranded polynucleotide Poly(A)-Poly(U). [Zn(X)TMPyP4] binding with Poly(A)-Po...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2016.05.004

    authors： Tolstykh G,Sizov V,Kudrev A

    更新日期：2016-08-01 00:00:00

  • Quinoline antimalarials decrease the rate of beta-hematin formation.

    abstract：:The strength of inhibition of beta-hematin (synthetic hemozoin or malaria pigment) formation by the quinoline antimalarial drugs chloroquine, amodiaquine, quinidine and quinine has been investigated as a function of incubation time. In the assay used, beta-hematin formation was brought about using 4.5M acetate, pH 4.5...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2005.04.013

    authors： Egan TJ,Ncokazi KK

    更新日期：2005-07-01 00:00:00

  • A ruthenium(II) complex containing a p-cresol group induces apoptosis in human cervical carcinoma cells through endoplasmic reticulum stress and reactive oxygen species production.

    abstract：:The chemical structures of Ru (II) complexes are known to affect their cellular behavior and toxicity. In this study, three new luminescent Ru (II) complexes, [Ru(bpy)2(HIPMP)](ClO4)2 (Ru1, bpy = 2,2'-bipyridine, HIPMP = 2-(1H-imidazo-[4,5-f] [1,10] phenanthrolin-2-yl)-4-methylphenol), [Ru(phen)2(HIPMP)](ClO4)2 (Ru2, ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2018.11.015

    authors： Xu L,Zhang PP,Fang XQ,Liu Y,Wang JQ,Zhou HZ,Chen ST,Chao H

    更新日期：2019-02-01 00:00:00

  • In vivo coordination structural changes of a potent insulin-mimetic agent, bis(picolinato)oxovanadium(IV), studied by electron spin-echo envelope modulation spectroscopy.

    abstract：:Bis(picolinato)oxovanadium(IV) [VO(pic)2] is one of the most potent insulin-mimetic vanadium complexes. To probe coordination structural changes of this complex in vivo and provide insights into the origin of its high potency, an electron spin-echo envelope modulation (ESEEM) study was performed on organs (kidney, liv...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0162-0134(99)00204-4

    authors： Fukui K,Fujisawa Y,OhyaNishiguchi H,Kamada H,Sakurai H

    更新日期：1999-11-01 00:00:00

  • Application of a self-modeling curve resolution approach to the study of solvent effects on the acid-base and copper (II)-complexing behavior of polyuridylic acid.

    abstract：:The solvent effect on the acid-base and complexation behavior of the homopolynucleotide polyuridylic acid (poly(U)) has been studied by means of potentiometric and spectrometric titrations (circular dichroism and UV-VIS) in water and in 30 and 50% (v/v) dioxane-water media. The potentiometric studies revealed the abse...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(95)00211-1

    authors： de Juan A,Fonrodona G,Gargallo R,Izquierdo-Ridorsa A,Tauler R,Casassas E

    更新日期：1996-08-15 00:00:00

  • The two distinctive metal ion binding domains of the wheat metallothionein Ec-1.

    abstract：:Metallothioneins are small cysteine-rich proteins believed to play a role, among others, in the homeostasis of essential metal ions such as Zn(II) and Cu(I). Recently, we could show that wheat E(c)-1 is coordinating its six Zn(II) ions in form of metal-thiolate clusters analogously to the vertebrate metallothioneins. ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2008.11.008

    authors： Peroza EA,Kaabi AA,Meyer-Klaucke W,Wellenreuther G,Freisinger E

    更新日期：2009-03-01 00:00:00

  • Ligand replacement study at the His120 site of purple CuA azurin.

    abstract：:The CuA center is a dinuclear Cu2S2(Cys) electron transfer center found in cytochrome c oxidase and nitrous oxide reductase. In a previous investigation of the equatorial histidine ligands' effect on the reduction potential, electron transfer and spectroscopic properties of the CuA center, His120 in the engineered CuA...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0162-0134(99)00214-7

    authors： Berry SM,Wang X,Lu Y

    更新日期：2000-01-15 00:00:00

  • The pH of HNO donation is modulated by ring substituents in Piloty's acid derivatives: azanone donors at biological pH.

    abstract：:A group of Piloty's acid (N-hydroxybenzenesulfonamide) derivatives were synthesized and fully characterized in order to assess the rates and pH of HNO (azanone, nitroxyl) donation in aqueous media. The derivatives, with electron-withdrawing and -donating substituents include methyl, nitro, fluoro, tri-isopropyl, trifl...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2012.10.008

    authors： Sirsalmath K,Suárez SA,Bikiel DE,Doctorovich F

    更新日期：2013-01-01 00:00:00

  • The effect of spermine concentration on the solution structure of complexes formed in copper(II)/adenosine 5'-triphosphate/phosphoserine system.

    abstract：:Quaternary systems of copper(II) complexes with adenosine 5'-triphosphate, O-phospho L-serine and with equimolar or excessive amount of spermine have been investigated. The studies have been performed in aqueous solution. Types of complexes and the overall stability constants have been determined using the potentiomet...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2010.04.006

    authors： Jastrzab R,Runka T,Skowronek P,Lomozik L

    更新日期：2010-08-01 00:00:00

  • Effects of cadmium on Na+ transport in the isolated skin of the toad Pleurodema thaul.

    abstract：:Cadmium ions applied to either (outer or inner) surface of the isolated toad skin dose-dependently increased the short-circuit current (SCC), the potential difference (V) and the active sodium conductance (G(Na)) in the concentration range 0.07-0.50mM. Maximal stimulatory effect was over 30% with an EC(50) of about 0....

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2005.09.003

    authors： Suwalsky M,Norris B,Cárdenas H

    更新日期：2005-12-01 00:00:00

  • Synthesis and characterization of novel platinum(IV) complexes with non-functionalized acetylated carbohydrates.

    abstract：:[PtMe3(Me2CO)3]BF4 (1) reacts in acetone with 1,2,3,4-tetraacetyl-beta-D-glucopyranose (C2), pentaacetyl-alpha-D-glucopyranose (C3), pentaacetyl-beta-D-mannopyranose (C4) and pentaacetyl-beta-D-galactopyranose (C5) to give trimethyl(carbohydrate)platinum tetrafluoroborate complexes [PtMe3L]BF4 (2-5) (2, L=C2; 3, L=C3;...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0162-0134(00)00088-x

    authors： Junicke H,Kluge R,Steinborn D

    更新日期：2000-07-15 00:00:00

  • Interactions of arene-Ru(II)-chloroquine complexes of known antimalarial and antitumor activity with human serum albumin (HSA) and transferrin.

    abstract：:The interactions of π-arene-Ru(II)-chloroquine complexes with human serum albumin (HSA), apotransferrin and holotransferrin have been studied by circular dichroism (CD) and UV-Visible spectroscopies, together with isothermal titration calorimetry (ITC). The data for [Ru(η(6)-p-cymene)(CQ)(H(2)O)Cl]PF(6) (1), [Ru(η(6)-...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2010.09.005

    authors： Martínez A,Suárez J,Shand T,Magliozzo RS,Sánchez-Delgado RA

    更新日期：2011-01-01 00:00:00

  • Synthesis, structural characterization, formation constants and in vitro cytotoxicity of phenanthroline and imidazolidine-2-thione copper(II) complexes.

    abstract：:The synthesis, crystal structures, physicochemical properties and complex formation constants of [Cu(phen)(2)(L)](ClO(4))(2) complexes, where phen is 1,10-ortho-phenanthroline and L is a series of substituted imidazolidine-2-thione, have been studied. Single crystal X-ray diffraction revealed a distorted trigonal-bipy...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2010.11.017

    authors： Pivetta T,Cannas MD,Demartin F,Castellano C,Vascellari S,Verani G,Isaia F

    更新日期：2011-03-01 00:00:00

  • Metalated nucleotide chemisorption on hydroxyapatite.

    abstract：:The experiments here reported evidence on the importance of the residual charge of a nucleotide derivative, for the adsorption on nHAP (hydroxyapatite nanocrystals), in water solution. We found that the simple presence of phosphates on the nucleotide derivative does not guarantee adsorption on nHAP. On the other hand,...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2015.04.006

    authors： Benedetti M,Antonucci D,De Castro F,Girelli CR,Lelli M,Roveri N,Fanizzi FP

    更新日期：2015-12-01 00:00:00

  • Interaction centres of purine nucleotides: adenosine-5'-diphosphate and adenosine-5'-triphosphate in their reactions with tetramines and Cu(II) ions.

    abstract：:The interactions between the nucleotides: adenosine-5'-diphosphate (ADP) and adenosine-5'-triphosphate (ATP) with spermine (Spm) and 1,11-diamine-4,8-diazaundecane (3,3,3-tet), as well as Cu(II) ions are studied. In the metal-free systems nucleotide-polyamine molecular complexes have been found to form, in which the i...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/s0162-0134(03)00150-8

    authors： Gasowska A

    更新日期：2003-08-01 00:00:00

  • Comparative study of reaction of cobalamin and cobinamide with thiocyanate.

    abstract：:The interaction of Co(III) and Co(II) cobalamin (Cbl) and cobinamide (Cbi) with thiocyanate was examined with UV-vis and EPR spectra. S/N-linkage isomerism was explored on Co(III) and Co(II) Cbl and Cbi models using density functional theory (DFT; BP86, B3LYP). Performed calculations suggest the prevalence of isothioc...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2013.04.011

    authors： Dereven'kov IA,Salnikov DS,Makarov SV,Surducan M,Silaghi-Dumitrescu R,Boss GR

    更新日期：2013-08-01 00:00:00

  • Improved syntheses of β-octabromo-meso-triarylcorrole derivatives.

    abstract：:In spite of significant applications as starting materials for a variety of metallocorrole derivatives, free-base β-octabromo-meso-triarylcorroles continue to be viewed as inaccessible. The reasons range from the need for tedious column-chromatographic purification to limitations of the reductive demetallation protoco...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2015.07.017

    authors： Capar J,Berg S,Thomas KE,Beavers CM,Gagnon KJ,Ghosh A

    更新日期：2015-12-01 00:00:00

  • Kinetics and mechanism of reactions of the drug tiopronin with platinum(IV) complexes.

    abstract：:Tiopronin, a synthetic thiol-containing drug being used in treatments of cystinuria and certain types of rare arthritis, is also a hepatoprotective and a detoxifying agent. Many analytical methods have been developed based on its redox chemistry with metal ions/complexes, but the kinetic and mechanistic aspects are po...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2013.04.003

    authors： Huo S,Shi H,Liu D,Shen S,Zhang J,Song C,Shi T

    更新日期：2013-08-01 00:00:00

  • Crystal structure based design of functional metal/protein hybrids.

    abstract：:Preparation of metal/protein hybrids is growing into important topics in the field of bioinorganic chemistry. X-ray crystal structure analyses of them provide direct information on unique interactions of metal cations or metal cofactors to understand and design enzymatic functions. In this mini review, the authors foc...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章,评审

    doi：10.1016/j.jinorgbio.2007.06.025

    authors： Ueno T,Yokoi N,Abe S,Watanabe Y

    更新日期：2007-11-01 00:00:00

  • Phytic acid-metal ion interactions. II. The effect of pH on Ca(II) binding.

    abstract：:The interaction of phytic acid with Ca(II) has been studied by potentiometric titration and by measurement of free Ca(II) concentrations using an ion Selective electrode. With increasing Ca(II) concentration, the titration curve of phytic acid is displaced to regions of lower pH. In the binding of calcium ions to phyt...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(86)80105-2

    authors： Martin CJ,Evans WJ

    更新日期：1986-05-01 00:00:00

  • Stability constants of copper(II) mixed complexes with some 4-quinolone antibiotics and (N-N) donors.

    abstract：:Studies of complexation equilibria of the antibiotic anions nalidixate and cinoxacinate with [Cu(phen)]2+ and [Cu(bipy)]2+ are reported. These studies indicate that the stability of this type of complex is strongly related to the metal environment. A correlation between the stability constants, determined here, with t...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(96)00041-4

    authors： Mendoza-Díaz G,Perez-Alonso R,Moreno-Esparza R

    更新日期：1996-11-15 00:00:00

  • Renal handling of amino acid 99mtechnetium chelates.

    abstract：:Four amino acids--alanine, 2,3-diaminopropionic acid, cystine, and cystein--and also one diamine, ethylenediamine, were chelated with 99m-technetium (99mTc), and their renal excretion patterns were studied in rabbits in the presence and absence of two renal tubular transport inhibitors, probenecid and 2,4-dinitropheno...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(88)85015-3

    authors： Chattopadhyay M,Banerjee S

    更新日期：1988-09-01 00:00:00

  • Reactions of model proteins with aurothiomalate, a clinically established gold(I) drug: The comparison with auranofin.

    abstract：:Aurothiomalate (AuTm) is an old, clinically established, antiarthritic gold drug that is currently being reconsidered as a candidate drug for cancer treatment and for other therapeutic indications within a more general drug repositioning program. As the biological effects of gold drugs seem to be mediated, mainly, by ...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2015.03.013

    authors： Darabi F,Marzo T,Massai L,Scaletti F,Michelucci E,Messori L

    更新日期：2015-08-01 00:00:00

  • Reaction of human ceruloplasmin and anion treated ceruloplasmin with diethyldithiocarbamate.

    abstract：:The reaction of human ceruloplasmin and anion treated ceruloplasmin with diethyldithiocarbamate was studied at pH 5.5. The analysis of optical and EPR spectra at 9 GHz showed that ceruloplasmin contains five paramagnetic copper ions, two of which, X and Y, not involved in enzymatic activity, are chelated by diethyldit...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/0162-0134(85)80020-9

    authors： Herve M,Garnier-Suillerot A,Tosi L,Steinbuch M

    更新日期：1985-10-01 00:00:00

  • Synthesis, characterization, and antitumor activity of unusual pseudo five coordinate gold(III) complexes: distinct cytotoxic mechanism or expensive ligand delivery systems?

    abstract：:Gold(III) complexes bearing bidentate ligands based on the 1,10-phenanthroline and 2,2'-bipyridine scaffolds have shown promising anticancer activity against a variety of tumor cell lines. In particular, our laboratory has previously found that a pseudo five coordinate gold(III) complex possessing the 2,9-di-sec-butyl...

    journal_title：Journal of inorganic biochemistry

    pub_type： 杂志文章

    doi：10.1016/j.jinorgbio.2014.08.014

    authors： Olsen PM,Ruiz C,Lussier D,Le BK,Angel N,Smith M,Hwang CB,Khatib R,Jenkins J,Adams K,Getcher J,Tham F,Chen ZG,Wilson EH,Eichler JF

    更新日期：2014-12-01 00:00:00