Six different mutations of TGFBI (betaig-h3, keratoepithelin) gene found in Japanese corneal dystrophies.

abstract：:The action of hydrogen peroxide on soluble proteins of the rat cornea has been evaluated. Two major corneal proteins are found to be oxidized by 10 mM hydrogen peroxide. Protein sequence and antibody recognition has shown one of the proteins to be albumin. Treatment of pure rat or human albumin with hydrogen peroxide ...

journal_title：Cornea

authors： Zhu L,Crouch RK

更新日期：1992-11-01 00:00:00

abstract：:We examined the surface epithelium of 30 eyes with color specular microscopy at 3-month intervals 1-18 months following penetrating keratoplasty. At least three examinations were performed on most eyes. We found a vortex keratopathy to be present in 70% of these eyes. In nine eyes, this vortex pattern was present at e...

journal_title：Cornea

authors： Mathers WD,Lemp MA

更新日期：1991-03-01 00:00:00

abstract：PURPOSE:Corneal transplantation is the standard of care for pediatric corneal opacities, but little consensus exists on optimal surgical management. Our goal was to evaluate cross-sectional data of donor and recipient characteristics collected from eye banks providing tissue for pediatric corneal transplant cases to as...

journal_title：Cornea

authors： Zhu AY,Prescott CR

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To analyze whether plasma rich in growth factors (PRGF) eye drops preserve their biological characteristics and activity after storage for 3 and 6 months at -20°C, at 4°C, and at room temperature for 72 hours, compared with fresh samples (t0). METHODS:Blood from 6 healthy donors was harvested and centrifuged t...

journal_title：Cornea

authors： Anitua E,de la Fuente M,Riestra A,Merayo-Lloves J,Muruzábal F,Orive G

更新日期：2015-09-01 00:00:00

abstract：:We performed a retrospective analysis of 291 consecutive scleral rim cultures, taken at the time of corneal transplantation, from 1981 to 1986. There were 82 positive cultures (39%), and the most common pathogen was Staphylococcus epidermidis, with 24 positive cultures (30%). Ten of these (42%) were resistant to genta...

journal_title：Cornea

authors： Mathers WD,Lemp MA

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To study the possible changes in Scheimpflug corneal densitometry 6 months after mitomycin C-augmented trabeculectomy and to compare these measurements with healthy controls. METHODS:Corneal densitometry was monitored with the Pentacam HR3 before and 6 months after first-time uncomplicated mitomycin C-augmente...

journal_title：Cornea

authors： Pillunat KR,Orphal J,Haase M,Pillunat LE,Herber R

更新日期：2020-07-27 00:00:00

abstract：PURPOSE:The aim of this study is to determine the effect of variation of the exposure time of near-infrared irradiation on corneal stiffening after a bacteriochlorophyll derivative (WST11) with dextran (WST-D) application. METHODS:One hundred four paired eyes of 3-month-old New Zealand White rabbits were included in t...

journal_title：Cornea

authors： Brekelmans J,Goz A,Dickman MM,Brandis A,Sui X,Wagner HD,Nuijts RMMA,Scherz A,Marcovich AL

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:To examine the immediate effect of ocular rubbing on corneal topography. METHODS:Corneal topography and analysis were performed before, immediately after, and 5 minutes after eyelid rubbing in 29 volunteers without ocular disease. RESULTS:The surface regularity index increased from a baseline of 0.24 to 0.91 ...

journal_title：Cornea

authors： Mansour AM,Haddad RS

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:To investigate the safety of intracameral injection of minimum bactericidal concentration (MBC) of povidone iodine (PI) on the corneal endothelium in a rabbit model as a proposed method of prophylaxis against postoperative endophthalmitis. METHODS:We included 32 New Zealand white rabbits in the study. Twenty-f...

journal_title：Cornea

authors： ElKitkat RS,Ebeid WM,Habib EK,Shoukry Y

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To confirm the ocular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by evaluating the expression of viral entry factors in human ocular tissues using immunohistochemistry. METHODS:Fresh donor corneas and primary explant cultures of corneal, limbal, and conjunctival epithelial cells we...

journal_title：Cornea

authors： Roehrich H,Yuan C,Hou JH

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:To investigate the morphological changes of corneal epithelium and subbasal nerves by in vivo confocal microscopy in patients with ocular surface disease (OSD) treated with cord blood serum (CBS) eye drops. METHODS:Twenty patients with OSD (mean age 61.1 ± 12.6 years) were included in this prospective 1-arm st...

journal_title：Cornea

authors： Giannaccare G,Buzzi M,Fresina M,Velati C,Versura P

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:Corneal inflammation in overnight contact lens (CL) wear is not fully understood. We designed a masked study to examine the impact of overnight CL wear on clinical variables in subjects who had previously experienced corneal inflammatory disease. METHODS:Forty-four subjects were entered into the study: Nine su...

journal_title：Cornea

authors： Stapleton F,Ramachandran L,Sweeney DF,Rao G,Holden BA

更新日期：2003-07-01 00:00:00

abstract：:Posterior polymorphous corneal dystrophy (PPD) is a rare bilateral, autosomal-dominant disease. The presence of the epitheliumlike endothelium and the thickening of Descemet's membrane by the posterior collagenous layer (PCL) has been reported in the majority of published cases. Reepithelialization of the posterior co...

journal_title：Cornea

authors： Sekundo W,Lee WR,Aitken DA,Kirkness CM

更新日期：1994-11-01 00:00:00

abstract：PURPOSE:This review discusses cellular senescence, the state in which normal cells do not respond to growth stimuli, and shows characteristic alterations in their cytologic and biochemical properties and their gene expression profiles. METHODS AND RESULTS:Cellular senescence is elicited by various stresses. It was rec...

journal_title：Cornea

authors： Ishikawa F

更新日期：2006-12-01 00:00:00

abstract：:Infectious keratitis after penetrating keratoplasty can be devastating to the survival of the graft and its visual outcome. From November 1989 to October 1994, we treated 41 episodes of late microbial keratitis among 354 consecutive penetrating keratoplasty patients and reviewed their medical records retrospectively. ...

journal_title：Cornea

authors： Tseng SH,Ling KC

更新日期：1995-11-01 00:00:00

abstract：:Salzmann's nodular degeneration is a rare, noninflammatory, slowly progressive, degenerative condition. Bluish-white nodules raised above the surface of the cornea characterize it. It has usually developed in corneas with a history of phlyctenulosis, trachoma, vernal keratoconjunctivitis, measles, scarlet fever, and v...

journal_title：Cornea

authors： Das S,Link B,Seitz B

更新日期：2005-10-01 00:00:00

abstract：PURPOSE:To determine the effectiveness of prophylactic fluoroquinolone treatment against staphylococci in a rabbit keratitis model. METHODS:Prophylactic ciprofloxacin or ofloxacin was applied as one topical drop 15 minutes before infection or as one drop at three time points (19, 17, and 15 minutes) before infection. ...

journal_title：Cornea

authors： Dajcs JJ,Moreau JM,Thibodeaux BA,Traidej M,Austin MS,Marquart ME,Stroman DW,O'Callaghan RJ

更新日期：2001-11-01 00:00:00

abstract：:Keratoconus is a progressive, noninflammatory, nonvascular axial corneal ectasia, with unclear etiology and pathogenesis. It has a prevalence of 50-230 per 100,000 and is a bilateral disorder in up to 90% of cases. The onset of keratoconus is usually at puberty and progresses over 10-20 years producing an irregular my...

journal_title：Cornea

authors： Bechrakis N,Blom ML,Stark WJ,Green WR

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:We aimed to evaluate a new technique using a thermosensitive glue coating for impression cytology of the ocular surface. METHODS:We prepared plasma polymerized N-isopropyl acrylamide (pNIPAM)-coated parylene C (poly(monochloro-p-xylylene)) films to obtain cytological samples from the conjunctival surface. We c...

journal_title：Cornea

authors： Tunc M,Yildirim U,Yuksel H,Cheng X,Humayun M,Ratner B

更新日期：2009-08-01 00:00:00

abstract：PURPOSE:To report the incidence of complications and the refractive results in patients with diabetes mellitus treated with laser-assisted in situ keratomileusis (LASIK). METHODS:A retrospective review of the charts, focusing on 6-month postoperative data, was performed on 30 eyes from patients with diabetes and 150 a...

journal_title：Cornea

authors： Fraunfelder FW,Rich LF

更新日期：2002-04-01 00:00:00

abstract：PURPOSE:To compare the relative diagnostic value of confocal microscopy and superficial corneal cultures in the diagnosis of Acanthamoeba keratitis by using clinical and microbiologic definitions of disease. METHODS:Results of confocal microscopy, superficial corneal smear, and superficial corneal culture were analyze...

journal_title：Cornea

authors： Tu EY,Joslin CE,Sugar J,Booton GC,Shoff ME,Fuerst PA

更新日期：2008-08-01 00:00:00

abstract：:Corneal intraepithelial neoplasia (CIN) is the term applied by some authors to the spectrum of disease ranging from mild dysplasia to carcinoma in situ. Such lesions usually are associated with dysplastic or neoplastic processes at the limbus or adjacent conjunctiva; isolated corneal dysplasia is rare. Clinically, CIN...

journal_title：Cornea

authors： Brown HH,Glasgow BJ,Holland GN,Foos RY

更新日期：1989-09-01 00:00:00

abstract：PURPOSE:To compare the results of repeat Descemet stripping automated endothelial keratoplasty (DSAEK) with those of primary DSAEK. MATERIALS AND METHODS:This retrospective study consisted of all consecutive eyes that underwent one or more repeat DSAEK surgeries after primary DSAEK performed at Villa Serena-Villa Igea...

journal_title：Cornea

authors： Nahum Y,Mimouni M,Madi S,Busin M

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:We quantitated herpes simplex virus (HSV) DNA in tear film obtained from 2 patients who developed herpetic epithelial keratitis (HEK) during treatment with latanoprost and a beta-blocker. METHODS:The patient in case 1 is a 77-year-old woman with bilateral open-angle glaucoma who had been treated with latanopro...

journal_title：Cornea

authors： Deai T,Fukuda M,Hibino T,Higaki S,Hayashi K,Shimomura Y

更新日期：2004-03-01 00:00:00

abstract：PURPOSE:The objective of this study was to produce a porcine corneal acellular matrix (ACM) and assess its possibility for biomedical applications. METHODS:Porcine corneas were treated with various concentrations of sodium dodecylsulfate for different lengths of time. Optimal conditions for processing the ACM were not...

journal_title：Cornea

authors： Zhou Y,Wu Z,Ge J,Wan P,Li N,Xiang P,Gao Q,Wang Z

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:This study was designed to report a case of acanthamoeba keratitis in a 5-year-old child without a history of trauma or contact lens usage. METHODS:The history, clinical presentation, diagnostic, and therapeutic approaches were reviewed. RESULTS:A 5-year-old child without any history of trauma or contact lens...

journal_title：Cornea

authors： Demirci G,Ay GM,Karabas LV,Altintas O,Tamer GS,Cağlar Y

更新日期：2006-04-01 00:00:00

abstract：PURPOSE:The significance of ocular or corneal aberrations may be subject to misinterpretation whenever eyes with different pupil sizes or the application of different Zernike expansion orders are compared. A method is shown that uses simple mathematical interpolation techniques based on normal data to rapidly determine...

journal_title：Cornea

authors： Smolek MK

更新日期：2012-03-01 00:00:00

abstract：:Previous studies suggest the existence of two separate and distinct mechanisms of endothelial wound healing (i.e., cell migration and cell spreading), which may be controlled by unique, injury-dependent, wound-related factors. The purpose of our study was to evaluate potential biologic mediators regulating healing of ...

journal_title：Cornea

authors： Petroll WM,Jester JV,Barry-Lane PA,Cavanagh HD

更新日期：1996-09-01 00:00:00

abstract：PURPOSE:This study investigated the topographic corneal thickness in four groups of Hong Kong Chinese. METHODS:The corneal thickness was determined with an ultrasound pachometer mounted on a X-Y plate. A head rest was used to reduce further any movement from the subject during the measurement. After the central cornea...

journal_title：Cornea

authors： Lam AK,Douthwaite WA

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:To determine the effects of single radial or horizontal suture placement in 2-step clear corneal incision (CCI) wound apposition and permeability to particles of India ink. METHODS:Five fresh human globes were included. Two 25-gauge needles connected to a saline solution bag and to a digital manometer were ins...

journal_title：Cornea

authors： May WN,Castro-Combs J,Kashiwabuchi RT,Tattiyakul W,Qureshi-Said S,Hirai F,Behrens A

更新日期：2013-03-01 00:00:00