Pharmacology of oxytocin and prostaglandins.

Abstract:

:Significant advances have been made in the last 20 years in our knowledge about the subcellular events occurring during myometrial contractions and cervical ripening and in the mechanism of action of oxytocin and prostaglandins. These advances have been instrumental in furthering our understanding of the mechanism of action of inhibitors of uterine contractility and have opened the door to clinical trials of agents such as specific COX-II inhibitors that may have the potential to inhibit labor without serious maternal or fetal side effects. There is still a long way to go, however, before all the complex actions of oxytocin and prostaglandins can be understood at a subcellular level, particularly the mechanism of action of prostaglandins in the process of cervical ripening.

journal_name

Clin Obstet Gynecol

authors

Arias F

doi

10.1097/00003081-200009000-00006

subject

Has Abstract

pub_date

2000-09-01 00:00:00

pages

455-68

issue

3

eissn

0009-9201

issn

1532-5520

journal_volume

43

pub_type

杂志文章,评审
  • Comparison of first and second trimester aneuploidy risk assessment.

    abstract::Counseling regarding the options for aneuploidy risk assessment is complicated and requires thorough counseling with the patient. Second trimester serum risk assessment has been the gold standard because of widespread availability, low cost, and vast experience with counseling and performance. First trimester risk ass...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e31804c9b99

    authors: Reddy UM,Wapner RJ

    更新日期:2007-06-01 00:00:00

  • Removal of adnexa at the time of vaginal hysterectomy.

    abstract::Removal of the fallopian tubes and ovaries at the time of vaginal hysterectomy is a skill that must be acquired if one is to be a competent vaginal surgeon. Various techniques have been described and will be reviewed in this chapter. A single technique or series of steps often must be modified depending on the descent...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e3181ce87fc

    authors: Shepherd JP,Zyczynski HM

    更新日期:2010-03-01 00:00:00

  • Plan A: postabortion contraception.

    abstract::More than 1 million abortions are performed annually in the United States. Women presenting for abortion care are often motivated by the pregnancy to use effective contraception; they are also at high risk for repeat unintended pregnancy. For these reasons, abortion represents an optimal time to initiate effective con...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000057

    authors: Micks E,Prager S

    更新日期:2014-12-01 00:00:00

  • Sonographic diagnosis of fetal growth disorders.

    abstract::In summary, accurate identification of fetal growth disorders remains a difficult clinical challenge. Many diagnostic parameters have been devised to diagnose these conditions, however, no single test alone allows a confident antenatal diagnosis of IUGR or macrosomia to be established. Until new criteria or new method...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-198803000-00007

    authors: Mintz MC,Landon MB

    更新日期:1988-03-01 00:00:00

  • Reversible antepartum fetal distress.

    abstract::Information generated from the various tests of fetal well-being must be interpreted correctly to avoid unnecessary intervention for assumed fetal distress. This applies to both the intrapartum and antenatal period. The presence of normal data (e.g., reassuring fetal heart rate tracing) allows the woman to continue co...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-198712000-00023

    authors: Nageotte MP

    更新日期:1987-12-01 00:00:00

  • Subclinical thyroid dysfunction during pregnancy.

    abstract::There is compelling data and a rationale for embarking on screening to identify pregnant women with some of the multiple classes of subclinical thyroid dysfunction. However, the evidence to support such screening and treatment is lacking. Several important trials are underway or undergoing peer review that may provide...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e31822e27e3

    authors: Casey BM

    更新日期:2011-09-01 00:00:00

  • A View From the UK: The UK and Ireland Confidential Enquiry into Maternal Deaths and Morbidity.

    abstract::The UK Confidential Enquiry into Maternal Deaths has been in operation for more than 60 years, during which time maternal mortality rates have fallen 10-fold. The program includes two aspects, surveillance and confidential case review, providing different information to aid quality improvement in maternity care. The e...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000352

    authors: Knight M,Tuffnell D

    更新日期:2018-06-01 00:00:00

  • Cesarean section for fetal distress.

    abstract::The avoidance of neonatal medical and neurologic sequelae resulting from a compromised pregnancy, labor, or delivery is the goal of all members of the health care team. Correct identification of those patients at risk for fetal distress prior to as well as during labor is most important as a major step in achieving th...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00003081-198528040-00010

    authors: Nageotte MP

    更新日期:1985-12-01 00:00:00

  • Amniotic and thromboembolism.

    abstract::Embolic phenomena in pregnancy demand rapid investigation and treatment. Regardless, some patients will not survive due to the enormity of the insult. Optimally, such patients should be treated in tertiary care centers, but this is not always possible. ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-199009000-00013

    authors: Chatelain SM,Quirk JG Jr

    更新日期:1990-09-01 00:00:00

  • Management of hypothyroidism during pregnancy.

    abstract::Hypothyroidism during pregnancy occurs in 1/1600-2000 deliveries, according to the most recent publications. The most common causes are chronic autoimmune thyroid disease, radiodine-131 treatment, or surgical removal. The diagnosis is difficult to make on clinical grounds alone, even in advanced cases, and a high inde...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-199703000-00008

    authors: Montoro MN

    更新日期:1997-03-01 00:00:00

  • Low-Molecular-Weight Heparin for the Prevention of Placenta-mediated Pregnancy Complications.

    abstract::During the past decade, prophylactic doses of low-molecular-weight heparin (LMWH) have been suggested to decrease the risk of placental-mediated complications. Herein, we review the prospective randomized trials that addressed the usefulness of LMWH in preventing placental-mediated complications in high-risk women. In...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0000000000000252

    authors: Haddad B,Lecarpentier E,Touboul C,Sibai BM

    更新日期:2017-03-01 00:00:00

  • Laparoscopic management of the adnexal mass.

    abstract::Ovarian neoplasms are common in women of all ages. As many as 10% of women in the United States will undergo surgical removal of an adnexal mass sometime in their lifetime. Gynecologic surgeons have pioneered laparoscopic surgery, developing what was originally a diagnostic tool into a safe and effective approach to m...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-200609000-00013

    authors: Hilger WS,Magrina JF,Magtibay PM

    更新日期:2006-09-01 00:00:00

  • Role of clinician involvement in patient safety in obstetrics and gynecology.

    abstract::Patient safety is a significant concern for healthcare providers. Involving physicians in clinical quality activities in obstetrics and gynecology can be difficult for many reasons including time demands, lack of knowledge of process improvement activities, or change fatigue due to failure of adequate implementation o...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e3181ec1b29

    authors: Mann S,Pratt S

    更新日期:2010-09-01 00:00:00

  • Caring for Opioid-dependent Pregnant Women: Prenatal and Postpartum Care Considerations.

    abstract::Pregnancy is an opportune time to identify opioid dependence, facilitate conversion to opioid maintenance treatment, and coordinate care with specialists in addiction medicine, behavioral health, and social services. Comprehensive prenatal care for opioid-dependent women involves the evaluation and the management of c...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000098

    authors: Krans EE,Cochran G,Bogen DL

    更新日期:2015-06-01 00:00:00

  • Surgery and Endometriosis.

    abstract::Care of the endometriosis patient today can be complex and difficult. Once medical management has been exhausted and symptoms persist patients desire further treatment options. This chapter takes an evidence-based approach at discussion of patient surgcical options for treatment of endometriosis symptoms. Surgical tec...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000291

    authors: Zanelotti A,Decherney AH

    更新日期:2017-09-01 00:00:00

  • Cervical assessment.

    abstract::The relationship between the clinical state of the cervix and spontaneous onset of labor has long been known. The cervix can be characterized by evaluating five parameters: effacement, dilatation, firmness, position, and level of the presenting part. The relative associations between successful labor induction and the...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-199506000-00005

    authors: Fuentes A,Williams M

    更新日期:1995-06-01 00:00:00

  • Operative vaginal delivery: a cause of birth injury or is it?

    abstract::Operative vaginal delivery has been maligned since the days of W.J. Little with the word "forceps" becoming nearly synonymous with "Birth Injury" and "Cerebral Palsy." However in his presentation to the Obstetrical Society of London in 1861, Little's emphasis was on difficult labors being the culprit in subsequent dis...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e31811eaa39

    authors: Towner DR,Ciotti MC

    更新日期:2007-09-01 00:00:00

  • GnRH agonists.

    abstract::The development of GnRH agonists has had a major impact on the practice of gynecology and reproductive endocrinology. The clinical usefulness of GnRH agonists will increase as modes of administration are improved and indications become better defined. GnRH agonists and, potentially, antagonists will provide a prompt, ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-198909000-00019

    authors: Schriock ED

    更新日期:1989-09-01 00:00:00

  • Genetic amniocentesis at 14 weeks or less.

    abstract::The recent clinical trials indicate that EA is feasible. The use of ancillary tools, such as ultrasound, requires only a slight modification of the previously established techniques for MA. The amniotic fluid can be obtained and cultured. Combining the reported populations sampled, the procedural and cytogenetic failu...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 临床试验,杂志文章,评审

    doi:10.1097/00003081-198806000-00011

    authors: Johnson A,Godmilow L

    更新日期:1988-06-01 00:00:00

  • The postpartum management of women with gestational diabetes using a continuum model for health care.

    abstract::Women with gestational diabetes mellitus require a continuum of care before, during, and after pregnancy for optimal management of hyperglycemia. Postpartum education and lifestyle modification should begin during pregnancy, and should continue during the postpartum period. Women should receive education on the long-t...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e3182a8e0bb

    authors: Castorino K,Jovanovič L

    更新日期:2013-12-01 00:00:00

  • Oral misoprostol administration for labor induction.

    abstract::Using oral agents for induction of labor would reduce the need for repeated vaginal examinations; this is more acceptable to women and could reduce infection rates. A systematic review was conducted of 41 randomized trials comparing oral misoprostol to other induction agents. Oral misoprostol is effective at achieving...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-200609000-00023

    authors: Weeks A,Alfirevic Z

    更新日期:2006-09-01 00:00:00

  • Influenza during pregnancy: a cause of serious infection in obstetrics.

    abstract::Influenza infection during pregnancy imparts disproportionate morbidity and mortality. This has been primarily noted during occasional influenza pandemics but also during seasonal epidemics. The majority of pregnant women who contract influenza appear to have a mild, self-limited course. However, influenza produces a ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0b013e31827146bd

    authors: Beigi RH

    更新日期:2012-12-01 00:00:00

  • Physiology of amniotic fluid volume regulation.

    abstract::Although there are fairly wide variations AFV normally undergoes characteristic changes across gestation in which it increases from 10-20 ml at 10 weeks gestation to average 800 ml at 24 weeks. Little change occurs from then until near term when AFV begins to decrease, and large decreases can occur in postterm pregnan...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-199706000-00005

    authors: Brace RA

    更新日期:1997-06-01 00:00:00

  • Fetal outcomes of elective delivery.

    abstract::Retrospective observational studies have suggested that delivery at or beyond 39 weeks has numerous neonatal benefits including less need for respiratory support, fewer neurodevelopmental delays and lower health care costs. This has lead governmental agencies, and professional organizations to endorse a policy of limi...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000030

    authors: Hoffman MK,Merriam AA,Ehrenthal DB

    更新日期:2014-06-01 00:00:00

  • Increasing Utilization of Minimally Invasive Hysterectomy.

    abstract::Once the decision to perform a hysterectomy has been made, the type and route of hysterectomy must be chosen, and efforts made to accomplish the surgery as safely as possible. Hysterectomy can be performed vaginally, abdominally with laparoscopic or robotic assistance, or open. The main goal of gynecologic surgeons sh...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/GRF.0000000000000283

    authors: Walters MD,Ridgeway BM

    更新日期:2017-06-01 00:00:00

  • Antenatal therapy to minimize neonatal intraventricular hemorrhage.

    abstract::Periventricular-intraventricular hemorrhage is an important problem, resulting in significant mortality and morbidity. Attempts to reduce this complication require an understanding of its pathogenesis. In this chapter a model was proposed, consisting of a series of events resulting in rapid changes of cerebral blood f...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-199106000-00014

    authors: Morales WJ

    更新日期:1991-06-01 00:00:00

  • Epidemiology and risk factors.

    abstract::HBC is common, accounting for approximately 9% of the total breast cancer burden. Given 142,000 cases of breast cancer expected to occur in 1989, this would represent 12,780 cases of HBC patients. Soberingly, each patient represents a family with a variable number of inordinately high risk patients. HBC's natural hist...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-198912000-00018

    authors: Lynch HT,Watson P,Lynch JF

    更新日期:1989-12-01 00:00:00

  • Robotic-assisted surgery for the community gynecologist: can it be adopted?

    abstract::The American College of Obstetricians and Gynecologists and the American Association of Gynecologic Laparoscopists confirm advantages of conventional minimally invasive surgery over laparotomy for benign gynecological procedures; however, adoption remains low for the general gynecologist. A systematic search for gynec...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e31822b4998

    authors: Payne TN,Pitter MC

    更新日期:2011-09-01 00:00:00

  • Errors and analysis of errors.

    abstract::Methods of analyzing errors and proactively preventing errors are discussed. A framework for using these concepts is presented. ...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/GRF.0b013e3181899a5a

    authors: Mulligan MA,Nechodom P

    更新日期:2008-12-01 00:00:00

  • Current evaluation and management of vulvovaginitis.

    abstract::There are many problems in the diagnosis and treatment of vaginitis. Often, the patient is not examined (telephone treatment) or examined improperly with lack of attention to the wet prep. In patients with recurrent vaginitis, it should not be assumed that the current infection is the same as a previous infection with...

    journal_title:Clinical obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/00003081-199906000-00004

    authors: Haefner HK

    更新日期:1999-06-01 00:00:00