Patient characteristics and treatments associated with a decline in upper-body function following breast cancer therapy.

Abstract:

:Breast cancer therapy is often followed by a decline in upper-body function. Women (303) diagnosed with stage I or II breast cancer were interviewed 5 and 21 months after surgery and their medical records were reviewed. Women with cardiopulmonary comorbidity had an odds ratio for decline at the 5-month interview of 2.8 (95% CI 1.3-5. 7), relative to women without. Women who received mastectomy (OR = 2. 5; 95% CI 0.9-6.7) or breast-conserving surgery with radiation therapy (OR = 2.9; 95% CI 1.0-8.9) were at higher risk for decline at the 5-month interview than women who received only breast-conserving surgery. Women who had axillary dissection were more likely to report numbness or pain in the axilla (OR = 6.4; 95% CI 1.2-33) at the 21-month interview than women who did not. Clinicians should consider the functional consequences of treatment when discussing treatment options and postoperative care with women who have early stage breast cancer.

journal_name

J Clin Epidemiol

authors

Lash TL,Silliman RA

doi

10.1016/s0895-4356(99)00176-6

subject

Has Abstract

pub_date

2000-06-01 00:00:00

pages

615-22

issue

6

eissn

0895-4356

issn

1878-5921

pii

S0895-4356(99)00176-6

journal_volume

53

pub_type

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