Antagonism of antinociception produced by intrathecal clonidine by ketorolac in the rat: the role of the opioid system.

abstract：:The purpose of this canine study was to examine the cerebral vascular and metabolic effects of adding nitrous oxide to isoflurane from 1.4% expired (1 MAC) up to a concentration giving an isoelectric electroencephalogram (EEG). Cerebral blood flow (CBF) and cerebral metabolic rate for oxygen (CMRO2) were determined us...

journal_title：Anesthesia and analgesia

authors： Roald OK,Forsman M,Heier MS,Steen PA

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Skeletal muscle failure in critical illness (intensive care unit-acquired weakness) is a well-known complication developing early during intensive care unit stay. However, muscle weakness during the perioperative setting has not yet been investigated. METHODS:We performed a subgroup investigation of a prosp...

journal_title：Anesthesia and analgesia

authors： Lachmann G,Mörgeli R,Kuenz S,Piper SK,Spies C,Kurpanik M,Weber-Carstens S,Wollersheim T,BIOCOG Consortium.

更新日期：2020-02-01 00:00:00

abstract：UNLABELLED:Systemically-administered morphine reduces infarct size in rat models of myocardial ischemia-reperfusion. We sought to determine whether much smaller doses of spinally-administered morphine offer a similar cardioprotective benefit. Barbiturate-anesthetized, open-chested, Wistar rats with chronic indwelling t...

journal_title：Anesthesia and analgesia

authors： Groban L,Vernon JC,Butterworth J

更新日期：2004-04-01 00:00:00

abstract：UNLABELLED:We sought to determine whether acute experimental allergic encephalomyelitis (EAE) alters the incorporation of epidurally administered [(3)H]-D-mannitol and [(14)C]-carboxyl-inulin into the lumbar spinal cord in rabbits. Acute EAE is an experimental model for demyelinating spinal cord diseases such as multip...

journal_title：Anesthesia and analgesia

authors： Naidu KA,Fu ES,Prockop LD

更新日期：2002-01-01 00:00:00

abstract：:The nucleus raphe magnus (NRM) is an important descending pain inhibitory system. We postulated that the analgesic action of supraspinally administered opiates results from increased descending inhibitory control of the NRM. We tested whether fentanyl activates NRM neurons in the rat slice preparation using extra-cell...

journal_title：Anesthesia and analgesia

authors： Ohta Y,Alojado ME,Kemmotsu O

更新日期：1995-05-01 00:00:00

abstract：:Laser Doppler flowmetry was used to further investigate the role of nitric oxide (NO) in CO2-induced cerebrocortical hyperemia in rats. A second objective was to elucidate the source(s) of the NO involved in the response to hypercapnia. We used the L-arginine analogue N omega-nitro-L-arginine methyl ester (L-NAME) to ...

journal_title：Anesthesia and analgesia

authors： Smith JJ,Lee JG,Hudetz AG,Hillard CJ,Bosnjak ZJ,Kampine JP

更新日期：1997-02-01 00:00:00

abstract：:The effect of the alpha 2-agonist dexmedetomidine on the cerebral blood flow (CBF) and the metabolic rate for oxygen was studied by a sagittal sinus outflow technique in dogs during halothane anesthesia. Dexmedetomidine was given in a dose (10 micrograms/kg) reported to reduce the anesthetic requirement of halothane b...

journal_title：Anesthesia and analgesia

authors： Karlsson BR,Forsman M,Roald OK,Heier MS,Steen PA

更新日期：1990-08-01 00:00:00

abstract：:Dilation of lymphatic vessels may contribute to iatrogenic dissemination of cancer cells during surgery. We sought to determine whether neuraxial anesthesia reduces regional lymphatic flow. Using nuclear lymphoscintigraphy, 5 participants receiving spinal anesthesia for brachytherapy had lower extremity lymph flow at ...

journal_title：Anesthesia and analgesia

authors： Hiller JG,Ismail HM,Hofman MS,Narayan K,Ramdave S,Riedel BJ

更新日期：2016-11-01 00:00:00

abstract：:Primary sensory nerves transmit information to both the periphery and central nervous systems, and they mediate neurogenic inflammation by release of neurotransmitters, such as tachykinins, in the periphery. Because the effect of local anesthetics on neurogenic inflammation is a subject of controversy, we investigated...

journal_title：Anesthesia and analgesia

authors： Takakura K,Mizogami M,Morishima S,Muramatsu I

更新日期：2006-09-01 00:00:00

abstract：UNLABELLED:We conducted a double-blinded study in 90 patients undergoing elective arthroscopic knee surgery to determine whether there is a role of inflammation in the analgesic efficacy of intraarticular piroxicam. Standardized general anesthetic techniques were used for all patients. At the end of the operation, afte...

journal_title：Anesthesia and analgesia

authors： Izdes S,Orhun S,Turanli S,Erkilic E,Kanbak O

更新日期：2003-10-01 00:00:00

abstract：:The interaction between nitrous oxide and diazepam was assessed in the mouse staircase test. In this paradigm, the numbers of rears (NR) (simultaneous standing on hindlegs and sniffing the air) and steps ascended (NSA) reflect anxiety and locomotor activity, respectively. Antianxiety drugs characteristically reduce NR...

journal_title：Anesthesia and analgesia

authors： Pruhs RJ,Quock RM

更新日期：1989-04-01 00:00:00

abstract：:Lidocaine decreases the minimum alveolar concentration (MAC) of inhaled anesthetics and has been used clinically to reduce the requirements for other anesthetic drugs. In this study we examined the effects of lidocaine on isoflurane MAC in cats. Six cats were studied. In Experiment 1, the MAC of isoflurane was determi...

journal_title：Anesthesia and analgesia

authors： Pypendop BH,Ilkiw JE

更新日期：2005-01-01 00:00:00

abstract：:In this study, we assessed the relationship between brain estimated specific gravity (eSG) and clinical symptoms, therapeutic intensity level, and outcome in human traumatic brain injury (TBI). Brain weight, volume, and eSG of the noncontused hemispheric areas were measured from computed tomography (CT) DICOM images o...

journal_title：Anesthesia and analgesia

authors： Degos V,Lescot T,Zouaoui A,Hermann H,Préteux F,Coriat P,Puybasset L

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:When temporary arterial occlusion of the parent artery is difficult for anatomical reasons, or when inadvertent aneurysmal rupture occurs during surgical dissection, adenosine administration can be used to produce flow arrest and brief, profound systemic hypotension that can facilitate intracranial aneurysm ...

journal_title：Anesthesia and analgesia

authors： Bebawy JF,Zeeni C,Sharma S,Kim ES,DeWood MS,Hemmer LB,Ramaiah VK,Bendok BR,Koht A,Gupta DK

更新日期：2013-11-01 00:00:00

abstract：:To improve operating room workflow, an internal transfer pricing system (ITPS) for anesthesia services was introduced in our hospital in 2001. The basic principle of the ITPS is that the department of anesthesia receives reimbursement only for the surgically controlled time, not for anesthesia-controlled time (ACT). A...

journal_title：Anesthesia and analgesia

authors： Schuster M,Standl T,Reissmann H,Kuntz L,Am Esch JS

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:In this study, we hypothesized that leg positioning and distal tourniquet application, when compared with neutral positioning of the leg, alters the efficacy of sciatic nerve block performed by the double-stimulation technique. METHODS:Ninety randomized, consecutive, ASA physical status I to III patients un...

journal_title：Anesthesia and analgesia

authors： Sertoz N,Deniz MN,Ayanoglu HO

更新日期：2011-12-01 00:00:00

abstract：:We studied 60 children undergoing elective surgery to evaluate the effect of interactions between vecuronium and isoflurane or halothane on the potency and duration of neuromuscular blockade, as measured by electromyography. Vecuronium was first administered by a logarithm-based cumulative method (14, 22, 35, 56, 89 m...

journal_title：Anesthesia and analgesia

authors： Pittet JF,Melis A,Rouge JC,Morel DR,Gemperle G,Tassonyi E

更新日期：1990-03-01 00:00:00

abstract：:We studied the effects of noxious stimuli on arterial blood pressure, heart rate, pupil size, and the pupillary light reflex in 13 volunteers anesthetized with either isoflurane or propofol. Those given isoflurane (n = 8) were anesthetized twice, in a randomly selected order, once at an end-tidal concentration of 0.8%...

journal_title：Anesthesia and analgesia

authors： Larson MD,Sessler DI,Washington DE,Merrifield BR,Hynson JA,McGuire J

更新日期：1993-05-01 00:00:00

abstract：:A response algorithm consists of a logical sequence of maneuvers to be performed in response to a specific condition. With the advent of alarm-equipped monitors that alert anesthesiologists to the presence of potentially hazardous clinical conditions, a need has arisen to develop the corresponding alarm-oriented respo...

journal_title：Anesthesia and analgesia

authors： Raphael DT,Weller RS,Doran DJ

更新日期：1988-09-01 00:00:00

abstract：:Neurotoxicity has been reported with tricyclic antidepressants (TCAs) used as local anesthetics. We examined the hypothesis that TCAs cause tissue injury, particularly myotoxicity, as occurs with many local anesthetics. Animals were given sciatic nerve injections with 0-80 mM doxepin, amitriptyline, or bupivacaine (1....

journal_title：Anesthesia and analgesia

authors： Barnet CS,Louis DN,Kohane DS

更新日期：2005-12-01 00:00:00

abstract：:Albino rats were chronically exposed for 40 hours a week to 10 ppm halothane in air during early development (conception to day 60), adult life (day 60 to day 135), or both. An unexposed group served as a control. Rats exposed during early development made 30 percent more errors than rats unexposed during this period ...

journal_title：Anesthesia and analgesia

authors： Quimby KL,Katz J,Bowman RE

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND:Sepsis is currently the leading cause of direct maternal death in the United Kingdom. In this study, we aimed to determine frequency, temporal trends, and independent associations for severe sepsis during hospitalization for delivery in the United States. METHODS:Data were obtained from the Nationwide Inpat...

journal_title：Anesthesia and analgesia

authors： Bauer ME,Bateman BT,Bauer ST,Shanks AM,Mhyre JM

更新日期：2013-10-01 00:00:00

abstract：:The effect of enflurane anesthesia on bronchomotor tone was studied in 15 dogs, using isolated tracheal segments in situ. In six animals, the changes of tracheal tension in response to changing enflurane concentration were continuously measured while keeping tidal volume, respiratory frequency, and end-tidal PCO2 cons...

journal_title：Anesthesia and analgesia

authors： Kochi T,Hagiya M,Mizuguchi T

更新日期：1989-07-01 00:00:00

abstract：:We were interested in determining the effect of enflurane, halothane, and isoflurane on the uptake and removal of 5-hydroxytryptamine (5-HT) and phenylethylamine (PEA) from the lung. Isolated rabbit lungs were perfused in a recirculating system in vitro with 0.1 microM [14C]5-HT or 0.1 microM [14C]PEA in Krebs-Ringer ...

journal_title：Anesthesia and analgesia

authors： Cook DR,Brandom BW

更新日期：1982-08-01 00:00:00

abstract：:Because deviations from the Meyer-Overton rule may provide insights into the attributes of the anesthetic site of action, we characterized the solubility of the n-alkanes in various hydrophobic solvents (n-tetradecane, olive oil, n-octanol, and lecithin) as well as saline using variations on standard techniques. Incre...

journal_title：Anesthesia and analgesia

authors： Taheri S,Laster MJ,Liu J,Eger EI 2nd,Halsey MJ,Koblin DD

更新日期：1993-07-01 00:00:00

abstract：:A quest for a systems-level neuroscientific basis of anesthetic-induced loss and return of consciousness has been in the forefront of research for the past 2 decades. Recent advances toward the discovery of underlying mechanisms have been achieved using experimental electrophysiology, multichannel electroencephalograp...

journal_title：Anesthesia and analgesia

authors： Hudetz AG,Mashour GA

更新日期：2016-11-01 00:00:00

abstract：:In view of the overall experience regarding regional anesthetic techniques to control postoperative pain in infants and children, it is feasible that a similar efficacy and safety profile can be obtained when using such techniques after major orthopedic procedures such as anterior or posterior spinal fusion. I reviewe...

journal_title：Anesthesia and analgesia

authors： Tobias JD

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:We tested the hypothesis that hypothyroidism, as defined by thyroid-stimulating hormone (TSH) concentration, is associated with a severity-weighted composite of mortality and major cardiovascular and infectious complications after noncardiac surgery. METHODS:In this retrospective cohort study, we evaluated ...

journal_title：Anesthesia and analgesia

authors： Komatsu R,You J,Mascha EJ,Sessler DI,Kasuya Y,Turan A

更新日期：2015-09-01 00:00:00

abstract：UNLABELLED:We investigated the physiological reaction to mobilization the first and second day after aortic valve replacement in an open, prospective study. Hemodynamic and oxygenation variables were recorded in 15 patients using a pulmonary artery oximetry catheter and bench oximetry. Serious intraoperative events occ...

journal_title：Anesthesia and analgesia

authors： Kirkeby-Garstad I,Sellevold OF,Stenseth R,Skogvoll E,Karevold A

更新日期：2004-02-01 00:00:00

abstract：UNLABELLED:Propofol and alfentanil are both rapid and short-acting drugs that can be used for sedation and analgesia during monitored anesthesia care (MAC). This study was designed to determine the optimal infusion rates of propofol and alfentanil when administered during local anesthesia. In this randomized, double-bl...

journal_title：Anesthesia and analgesia

authors： Avramov MN,White PF

更新日期：1997-09-01 00:00:00