Abstract:
OBJECTIVES:To assess the prevalence of enzyme sensitisation in the detergent industry. METHODS:A cross sectional study was conducted in a detergent factory. Sensitisation to enzymes was examined by skin prick and radioallergosorbent (RAST) tests. 76 Workers were tested; 40 in manufacturing, packing, and maintenance, and 36 non-exposed people in management and sales departments. The workers were interviewed for work related respiratory and skin symptoms. Total dust concentrations were measured by a gravimetric method, and the concentration of protease in air by a catalytic method. RESULTS:Nine workers (22%) were sensitised to enzymes in the exposed group of 40, whereas none were sensitised in the non-exposed group. All the sensitised people had symptoms at work; all had rhinitis and one had asthma. Protease concentrations were generally < 20 ng/m3, but occasional peak values up to 80 ng/m3 were detected in the packing and maintenance tasks, and high values of > 1 microgram/m3 in the mixing area. CONCLUSION:Despite the use of encapsulated enzyme preparations, high enzyme concentrations in workplace air are possible, resulting in a higher risk of sensitisation than expected.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Vanhanen M,Tuomi T,Tiikkainen U,Tupasela O,Voutilainen R,Nordman Hdoi
10.1136/oem.57.2.121subject
Has Abstractpub_date
2000-02-01 00:00:00pages
121-5issue
2eissn
1351-0711issn
1470-7926journal_volume
57pub_type
杂志文章abstract:AIMS:To evaluate an epidemiological approach to a national noise hazard surveillance strategy, and report current exposure levels in the Danish workplace. METHODS:A study base of 840 companies in 10 selected high risk industries in the largest county in Denmark was identified from a national register. Noise exposure w...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.012757
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVES:Limited evidence suggests the association between severity of acute occupational pesticide poisoning and depressive symptoms in farmers. The aim of this study was to investigate the association between occupational pesticide exposure and depressive symptoms among male farmers in South Korea. METHODS:A natio...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2012-101005
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the effects of chronic exposure to lead on the peripheral nervous system in lead workers. METHODS:Nerve conduction velocity and electromyographic studies were performed on 31 lead workers of a battery recycling factory and 31 sex and age matched controls. 25 cases with mild distal extensor weakn...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.6.415
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVES:Leukaemia is the most common cancer in children, but its aetiology is still poorly understood. We tested the hypothesis that traffic-related air pollution is associated with paediatric leukaemia because of chronic exposure to several potential carcinogens. METHODS:The Italian SETIL study (Study on the aetio...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2013-101604
更新日期:2013-12-01 00:00:00
abstract:AIMS:To examine the effect of silica exposure, in the absence of silicosis, on the prevalence of pulmonary tuberculosis (PTB), which is epidemic among South African gold miners. METHODS:Cross-sectional study of 520 gold miners over 37 years of age. Length of service, and cumulative and average dust and quartz exposure...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.018614
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVES:To elucidate factors contributing to hard metal asthma, the entire workforce of a corporation producing hard metal tools (n = 703) was examined. METHODS:The variables evaluated were the atopy reflected by immunoglobulin E (IgE) antibody against mite allergen, history of exposure to hard metal, smoking, conc...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.3.188
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:Occupational workload has been associated with an increased risk of osteoarthritis. The objective was to further examine the association between workload and occurrence of osteoarthritis and in particular to study whether heavy workload has similar importance as a causative factor for osteoarthritis of the hi...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2007.033365
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVES:To investigate whether an increased risk of cardiovascular disease might be caused by increased arrhythmogeneity and by unfavourable changes in autonomic cardiac control the changes in the occurrence of premature complexes (PVCs) and in heart rate variability (HRV) were studied in subjects who started to wor...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.58.10.678
更新日期:2001-10-01 00:00:00
abstract:AIMS:To investigate the use of a worker based methodology to assess the physical stresses of lifting tasks on effort expended, and to associate this loading with musculoskeletal outcomes (MO). METHODS:A cross sectional study was conducted on 217 male manual handling workers from the Hong Kong area. The effects of four...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.10.730
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:To study the effect on the incidence of cancer of exposure to chemicals handled in the leather tanning industry. MATERIALS AND METHODS:A case-control study was performed within a cohort of 2487 workers employed for at least six months during the period 1900-89 in three Swedish leather tanneries. 68 cancer ca...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.7.463
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:It has been speculated on theoretical grounds that biomarkers are superior surrogates for chemical exposures to air samples in epidemiology studies. METHODS AND RESULTS:Biomarkers were classified according to their position in the exposure-disease continuum-that is, parent compound, reactive intermediate, s...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.013102
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVES:Animal studies suggest that exposure to pesticides may alter thyroid function; however, few epidemiologic studies have examined this association. We evaluated the relationship between individual pesticides and thyroid function in 679 men enrolled in a substudy of the Agricultural Health Study, a cohort of li...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2017-104431
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Systematic assessments of the effectiveness of interventions to prevent work related eye injuries are needed. AIM:To investigate the long term effectiveness of a multicomponent prevention campaign. METHODS:The campaign (conducted in collaboration with the local Employers' Association and Trade Unions) targ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.019570
更新日期:2005-12-01 00:00:00
abstract:OBJECTIVES:To investigate the question of whether there is an association between workplace exposures and sociodemographic factors and mortality from non-malignant respiratory disease excluding influenza and pneumonia (NMRDxIP) among workers in a fibreglass wool manufacturing facility. METHODS:A case-control study wit...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.59.6.369
更新日期:2002-06-01 00:00:00
abstract:OBJECTIVES:Reliable retrospective exposure assessment continues to be a challenge in most population-based studies. Several methodologies exist for estimating exposures retrospectively, of which case-by-case expert assessment and job-exposure matrices (JEMs) are commonly used. This study evaluated the reliability of ex...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2011-100556
更新日期:2012-10-01 00:00:00
abstract:AIMS:To assess the prevalence of general health status, use of sleep medication, and use of medication for cardiovascular diseases, and to study their relation to aircraft noise exposure. METHODS:These health indicators were measured by a cross-sectional survey among 11 812 respondents living within a radius of 25 km ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2002.005488
更新日期:2004-05-01 00:00:00
abstract:AIMS:(1) To develop a transparent and broadly applicable method for assessing occupational safety and health (OSH) programmes or management systems; (2) to assess OSH programmes in a sample of manufacturing worksites; and (3) to determine whether a management focused occupational health intervention results in greater ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2003.011718
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:To investigate associations between cancer incidence and exposure to coal tar pitch volatiles, asbestos, pot emissions (fluorides, sulphur dioxide), heat stress, and magnetic fields in workers from a Norwegian aluminium smelter that operated from 1914 to 1975. METHODS:Cancer incidence between 1953 and 1991 w...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.4.250
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVES:To describe workers with low back symptoms, to identify risk factors and to assess the occupational consequences separately in men and women. METHODS:A descriptive study was conducted between 1 October 1996 and 31 December 1996 in a sample of workers selected at random from all types of small companies in t...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.10.696
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVES:Foundry work is a risk factor for lung cancer; however, the association with welding is unclear, as smoking is common among metalworkers and may mask the relationship. We evaluated whether history of welding and foundry work, independently and jointly, and employment duration were associated with lung cancer...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,随机对照试验
doi:10.1136/oemed-2016-104168
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:A prospective cohort study was designed to clarify the relations between occupational exposure to carbon disulphide (CS2) and its effects on arteriosclerosis in workers in 11 Japanese rayon manufacturing factories. This report is a cross sectional baseline observation in the first study year. METHODS:Study s...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.7.468
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVES:To investigate the occurrence of sick building syndrome in a tropical city, and its relation to indoor air quality and other factors. METHODS:2856 office workers in 56 randomly selected public and private sector buildings were surveyed. The study consisted of a self administered questionnaire assessing symp...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.3.188
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVES:There have been few studies of work history and mortality risks in medical radiation workers. We expanded by 11 years and more outcomes our previous study of mortality risks and work history, a proxy for radiation exposure. METHODS:Using Cox proportional hazards models, we estimated mortality risks accordin...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2013-101859
更新日期:2014-12-01 00:00:00
abstract::Internationally, the debate on aims for occupational health policy is expanding its horizons. Included among the issues are not only concerns about safety for workers, but also for their progeny. Equality among the sexes is also assuming a prominent position. In several countries, existing and proposed legislation alr...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.52.5.294
更新日期:1995-05-01 00:00:00
abstract:OBJECTIVES:To investigate the relation between shift work and death from ischaemic heart disease (IHD). METHODS:A nested case-control approach was used. The cohort comprised male manual workers who joined an industrial company aged 50 years or under between 1 January 1950 and 31 December 1992 and worked there for at l...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.6.367
更新日期:1996-06-01 00:00:00
abstract:AIMS:To investigate the acute systemic inflammatory response to welding fume exposure. METHODS:Twenty four welders (42% smokers) and 13 non-exposed controls (23% smokers) were monitored at a welding school. Exposure to fine particulate matter (PM2.5) was assessed using cyclone samplers. Markers of systemic inflammatio...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.014795
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:For the retrospective study of environment and health linkages biomarkers of exposure are required. Polychlorinated dibenzo-dioxins and furans (PCDD/F) and polychlorinated biphenyls (PCBs) have been useful markers in some settings. This is the first study of PCDD/F body burden in a population based sample fr...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.018754
更新日期:2005-12-01 00:00:00
abstract:OBJECTIVES:To estimate the annual rates of self reported occupational asthma in different occupational groups in Sweden. METHODS:All claims of occupational asthma 1990-2 in the Swedish register of reported occupational diseases were classified according to occupation. The number of people employed in each occupational...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.11.757
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVES:A hospital based case-control study was conducted between 1992 and 1993 in the province of Brescia, a highly industrialised area in northern Italy, to evaluate occupational risk factors of bladder cancer. METHODS:The study evaluated 355 histologically confirmed cases of bladder cancer (275 men, 80 women) an...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.1.6
更新日期:1996-01-01 00:00:00
abstract:CONTEXT:More than 400,000 workers annually receive a measurable radiation dose and may be at increased risk of radiation-induced leukaemia. It is unclear whether leukaemia risk is elevated with protracted, low-dose exposure. OBJECTIVE:We conducted a meta-analysis examining the relationship between protracted low-dose ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1136/oem.2009.054684
更新日期:2011-06-01 00:00:00