Effects of continuous positive airway pressure on sleep apnea and ventricular irritability in patients with heart failure.

abstract：BACKGROUND:Iron deficiency is common in patients with heart failure (HF) and is associated with reduced exercise capacity and poor outcomes. Whether correction of iron deficiency with (intravenous) ferric carboxymaltose (FCM) affects peak oxygen consumption [peak VO2], an objective measure of exercise intolerance in HF...

journal_title：Circulation

authors： van Veldhuisen DJ,Ponikowski P,van der Meer P,Metra M,Böhm M,Doletsky A,Voors AA,Macdougall IC,Anker SD,Roubert B,Zakin L,Cohen-Solal A,EFFECT-HF Investigators.

更新日期：2017-10-10 00:00:00

abstract：:The thienopyridines ticlopidine and clopidogrel are inhibitors of platelet function in vivo. Their mode of action has not been defined, but it appears that they require conversion to as yet unidentified metabolites that are noncompetitive antagonists of the platelet ADP receptor. Inhibition of platelet aggregation wit...

journal_title：Circulation

authors： Quinn MJ,Fitzgerald DJ

更新日期：1999-10-12 00:00:00

abstract：:We studied six patients who suffered from angina pectoris but had angiographically patent major coronary arteries. Two of the patients suffered also from congestive heart failure. Three patients had supraventricular tachyarrhythmias. Three patients had conduction disturbances. During coronary angiography the patients ...

journal_title：Circulation

authors： Mosseri M,Yarom R,Gotsman MS,Hasin Y

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:The cellular content of cAMP generated by activation of adenylylcyclase (AC) through the beta-adrenergic receptor (betaAR) is a key determinant of a cell's response to catecholamine stimulation. We tested the hypothesis that increased AC content, independently of betaAR number, increases responsiveness to ca...

journal_title：Circulation

authors： Gao MH,Lai NC,Roth DM,Zhou J,Zhu J,Anzai T,Dalton N,Hammond HK

更新日期：1999-03-30 00:00:00

abstract：BACKGROUND:Intracoronary stents may be effective when used as "bail-out" devices for acute complications after percutaneous transluminal coronary angioplasty. Furthermore, preliminary reports have demonstrated some promising results with stents with regard to the reduction of restenosis. Several stent devices are avail...

journal_title：Circulation

authors： van der Giessen WJ,Serruys PW,van Beusekom HM,van Woerkens LJ,van Loon H,Soei LK,Strauss BH,Beatt KJ,Verdouw PD

更新日期：1991-05-01 00:00:00

abstract：:Fibrinopeptide A, platelet factor 4, beta-thromboglobulin, thromboxane B2, and 6-keto-prostaglandin F1 alpha were estimated by radioimmunoassay on venous plasma samples taken within 48 hr of admission from 16 consecutive patients with unstable angina and 15 patients with stable angina matched for clinical variables. T...

journal_title：Circulation

authors： Théroux P,Latour JG,Léger-Gauthier C,De Lara J

更新日期：1987-01-01 00:00:00

abstract：:Contracture and collapse often complicate dissection and excision of blood vessels for grafting. Subsequent forceful redilatation and leak checking with cold saline almost always lead to partial or total denudation of endothelium, which increases the risk of early occlusion by thrombi or late occlusion by fibrocellula...

journal_title：Circulation

authors： Haudenschild C,Gould KE,Quist WC,LoGerfo FW

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Acute coronary ischemia is usually initiated by rupture of atherosclerotic plaque, leading to intracoronary thrombosis and clinical sequelae. The proximate cause of plaque rupture is unknown. Accordingly, we investigated the potential role of the 92-kD gelatinase member of the matrix metalloproteinase family...

journal_title：Circulation

authors： Brown DL,Hibbs MS,Kearney M,Loushin C,Isner JM

更新日期：1995-04-15 00:00:00

abstract：:Syncope and sudden death occurs in certain purebred Pug dogs which have been found to have intermittent sinus pauses and paroxysmal second degree heart block on electrocardiographic (ECG) study. We have established a colony of such dogs to study this problem and here report the results of histological examination of t...

journal_title：Circulation

authors： James TN,Robertson BT,Waldo AL,Branch CE

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:The pathogenesis of impaired endothelium-dependent coronary vasodilation in angina pectoris and normal coronary arteriograms (microvascular angina pectoris) is not known. We examined whether supplementation with L-arginine, a precursor of endothelium-derived nitric oxide, improves endothelium-dependent coron...

journal_title：Circulation

authors： Egashira K,Hirooka Y,Kuga T,Mohri M,Takeshita A

更新日期：1996-07-15 00:00:00

abstract：:To assess whether gross pathologic differences exist between hearts with left bundle branch block (LBBB) and left-axis deviation (LAXD) and those with LBBB and a normal frontal plane axis, we examined 70 hearts with LBBB in a series of 1410 sequential dissections (5%). Thirty-two hearts had LAXD and 34 had normal axes...

journal_title：Circulation

authors： Havelda CJ,Sohi GS,Flowers NC,Horan LG

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase-9 could exhibit an important role in the destabilization of atherosclerotic carotid plaques. We hypothesized that in patients with carotid stenosis, elevated levels of plasma matrix metalloproteinase-9 are associated with ipsilateral stroke or cardiovascular death. METHODS AND RESUL...

journal_title：Circulation

authors： Eldrup N,Grønholdt ML,Sillesen H,Nordestgaard BG

更新日期：2006-10-24 00:00:00

abstract：BACKGROUND:Early graft failure after the use of less satisfactory autologous grafts (30% of all vein grafts) is caused primarily by the following problems: (1) suitable autologous transplants are limited; (2) biotechnology has not yet been able to produce reliable graft substitutes that are legally and ethically approv...

journal_title：Circulation

authors： Lamm P,Juchem G,Milz S,Schuffenhauer M,Reichart B

更新日期：2001-09-18 00:00:00

abstract：:Hemodynamic and clinical evaluations of 123 patients with acute myocardial infarction were performed during the first hour of admission to the hospital. In the 123 patients, the right atrial pressure was less than 10 mm Hg in 49 patients, the right atrial oxygen saturation was less than 70% in 97 patients, the arterio...

journal_title：Circulation

authors： Ramo BW,Myers N,Wallace AG,Starmer F,Clark DO,Whalen RE

更新日期：1970-10-01 00:00:00

abstract：:The efficacy of a single oral dose combination of 120 mg diltiazem and 160 mg propranolol in terminating paroxysmal supraventricular tachycardia (PSVT) was evaluated in 15 patients. All 15 patients underwent electrical induction of PSVT that lasted longer than 15 min, and all underwent randomized crossover placebo and...

journal_title：Circulation

authors： Yeh SJ,Lin FC,Chou YY,Hung JS,Wu D

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Plasma C-reactive protein (CRP) concentrations are increased in obese and/or hyperinsulinemic individuals. The goal of this study was to determine if the relation between insulin resistance and CRP was independent of obesity. METHODS AND RESULTS:Plasma CRP concentrations were measured before and after 3 mon...

journal_title：Circulation

authors： McLaughlin T,Abbasi F,Lamendola C,Liang L,Reaven G,Schaaf P,Reaven P

更新日期：2002-12-03 00:00:00

abstract：BACKGROUND:The aim of the study was to establish the influence of proximal coronary artery atheroma and smoking habit on the stimulated release of tissue plasminogen activator (tPA) from the heart. METHODS AND RESULTS:After diagnostic coronary angiography in 25 patients, the left anterior descending coronary artery (L...

journal_title：Circulation

authors： Newby DE,McLeod AL,Uren NG,Flint L,Ludlam CA,Webb DJ,Fox KA,Boon NA

更新日期：2001-04-17 00:00:00

abstract：BACKGROUND:The possible contribution of endothelin-1, a potent endothelium-derived vasoconstrictor peptide, to neurohumoral compensation for hemodynamic stress was examined in nine normal volunteers and six patients with severe congestive heart failure. METHODS AND RESULTS:Plasma levels of endothelin-1 were measured w...

journal_title：Circulation

authors： Stewart DJ,Cernacek P,Costello KB,Rouleau JL

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Short-term hibernating myocardium is characterized by a decrease in contractile function in proportion to the reduced myocardial blood flow. Myocardial creatine phosphate content, initially decreased during the first minutes of ischemia, returns to near-control values, the ischemia-induced net lactate produc...

journal_title：Circulation

authors： Schulz R,Rose J,Martin C,Brodde OE,Heusch G

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Previous electrophysiological studies in patients with typical atrial flutter suggested that the slow conduction zone might be located in the low right atrial isthmus, which is a path formed by orifice of inferior vena cava, eustachian valve/ridge, coronary sinus ostium, and tricuspid annulus. The conduction...

journal_title：Circulation

authors： Tai CT,Chen SA,Chiang CE,Lee SH,Ueng KC,Wen ZC,Huang JL,Chen YJ,Yu WC,Feng AN,Chiou CW,Chang MS

更新日期：1997-10-21 00:00:00

abstract：BACKGROUND:Coronary sinus access by electrode catheters is easier in patients with atrioventricular junctional reentry tachycardia (AVJRT) than in patients with other supraventricular tachyarrhythmias. The reason for this has not been addressed. METHODS AND RESULTS:The size and shape of the proximal coronary sinus wer...

journal_title：Circulation

authors： Doig JC,Saito J,Harris L,Downar E

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:The future risk of myocardial infarction is commonly assessed using cardiovascular risk scores, coronary artery calcium score, or coronary artery stenosis severity. We assessed whether noncalcified low-attenuation plaque burden on coronary CT angiography (CCTA) might be a better predictor of the future risk ...

journal_title：Circulation

authors： Williams MC,Kwiecinski J,Doris M,McElhinney P,D'Souza MS,Cadet S,Adamson PD,Moss AJ,Alam S,Hunter A,Shah ASV,Mills NL,Pawade T,Wang C,Weir McCall J,Bonnici-Mallia M,Murrills C,Roditi G,van Beek EJR,Shaw LJ,Nicol E

更新日期：2020-05-05 00:00:00

abstract：:One hundred eighty-eight patients with acute myocardial infarction were studied prospectively from August 1980 to September 1982. One hundred thirty-six of these patients were entered into a intracoronary streptokinase study after informed consent was obtained. The remaining 52 patients, who either met exclusion crite...

journal_title：Circulation

authors： Smalling RW,Fuentes F,Matthews MW,Freund GC,Hicks CH,Reduto LA,Walker WE,Sterling RP,Gould KL

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Few studies have examined the association of race and outcomes after coronary artery bypass graft (CABG) surgery while controlling for both patient and hospital effects. METHODS AND RESULTS:We retrospectively analyzed data on a cohort of 566,785 white and 24,354 black Medicare beneficiaries 65 years old and...

journal_title：Circulation

authors： Konety SH,Vaughan Sarrazin MS,Rosenthal GE

更新日期：2005-03-15 00:00:00

abstract：BACKGROUND:We have previously suggested that the primary arterial switch operation is a feasible strategy for patients with transposition of the great arteries and intact ventricular septum (TGA-IVS) up to age 2 months. This study reports our current results with this approach and examines whether this policy could be ...

journal_title：Circulation

authors： Kang N,de Leval MR,Elliott M,Tsang V,Kocyildirim E,Sehic I,Foran J,Sullivan I

更新日期：2004-09-14 00:00:00

abstract：BACKGROUND:Women receive less evidence-based medical care than men and have higher rates of death after acute myocardial infarction (AMI). It is unclear whether efforts undertaken to improve AMI care have mitigated these sex disparities in the current era. METHODS AND RESULTS:Using the Get With the Guidelines-Coronary...

journal_title：Circulation

authors： Jneid H,Fonarow GC,Cannon CP,Hernandez AF,Palacios IF,Maree AO,Wells Q,Bozkurt B,Labresh KA,Liang L,Hong Y,Newby LK,Fletcher G,Peterson E,Wexler L,Get With the Guidelines Steering Committee and Investigators.

更新日期：2008-12-16 00:00:00

abstract：BACKGROUND:High-altitude pulmonary edema (HAPE) is characterized by pulmonary hypertension, increased pulmonary capillary permeability, and hypoxemia. Treatment is limited to descent to lower altitude and administration of oxygen. METHODS AND RESULTS:We studied the acute effects of inhaled nitric oxide (NO), 50% oxyge...

journal_title：Circulation

authors： Anand IS,Prasad BA,Chugh SS,Rao KR,Cornfield DN,Milla CE,Singh N,Singh S,Selvamurthy W

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Clinical depression is associated with an increased risk for mortality in patients with a recent myocardial infarction (MI). Reduced heart rate variability (HRV) has been suggested as a possible explanation for this association. The purpose of this study was to determine if depression is associated with redu...

journal_title：Circulation

authors： Carney RM,Blumenthal JA,Stein PK,Watkins L,Catellier D,Berkman LF,Czajkowski SM,O'Connor C,Stone PH,Freedland KE

更新日期：2001-10-23 00:00:00

abstract：BACKGROUND:The therapeutic effects of nonspecific beta-blockers are limited by vasoconstriction, thus justifying the interest in molecules with ancillary vasodilating properties. Nebivolol is a selective beta1-adrenoreceptor antagonist that releases nitric oxide (NO) through incompletely characterized mechanisms. We id...

journal_title：Circulation

authors： Dessy C,Saliez J,Ghisdal P,Daneau G,Lobysheva II,Frérart F,Belge C,Jnaoui K,Noirhomme P,Feron O,Balligand JL

更新日期：2005-08-23 00:00:00

abstract：:In Phase I of the NHLBI trial of Thrombolysis in Myocardial Infarction (TIMI), 290 patients admitted within 7 hr after onset of acute infarction were randomly assigned to intravenous treatment with either streptokinase (SK) or recombinant tissue-type plasminogen activator (rt-PA). Left ventricular function was measure...

journal_title：Circulation

authors： Sheehan FH,Braunwald E,Canner P,Dodge HT,Gore J,Van Natta P,Passamani ER,Williams DO,Zaret B

更新日期：1987-04-01 00:00:00