Generation of activity-rest patterns by dual circadian pacemaker systems: a model.

Abstract:

:Activity-rest patterns displayed by an animal under various circumstances are suggested to result from the combined influences of two virtually identical circadian pacemaker components. Increased output of each component proportionally increases the probability of activity of the animal. Such a dual circadian pacemaker model explains much of the phenomenology of activity-rest records. Under normal light-dark schedules, the two components of the model have a similar phase relationship to the Zeitgeber. Differential synchronization of the components to dawn and dusk is not assumed.

journal_name

J Sleep Res

authors

Beersma DG,Daan S

doi

10.1111/j.1365-2869.1992.tb00015.x

subject

Has Abstract

pub_date

1992-06-01 00:00:00

pages

84-87

issue

2

eissn

0962-1105

issn

1365-2869

pii

jsr001002084

journal_volume

1

pub_type

杂志文章
  • Fatigue-related impairment in the speed, accuracy and variability of psychomotor performance: comparison with blood alcohol levels.

    abstract::Cognitive performance is impaired by fatigue arising from sustained wakefulness and alcohol. Three recent papers directly compared the effects of increasing fatigue and blood alcohol concentration (%BAC) to provide a framework for understanding fatigue-related cognitive impairment. While the expression of fatigue-rela...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2004.00438.x

    authors: Maruff P,Falleti MG,Collie A,Darby D,McStephen M

    更新日期:2005-03-01 00:00:00

  • Spontaneous phasic activity in the brain: differences between waves in lateral geniculate and central lateral nuclei across sleep states.

    abstract::Ponto-geniculo-occipital (PGO) waves are spontaneously-occurring macropotential waveforms recorded in the pons, lateral geniculate body (LGB) and occipital cortex. PGO waves mark the onset and course of rapid eye movement sleep (REM). PGO-like waves can be recorded in several brain areas including the thalamic central...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.1992.tb00048.x

    authors: Sanford LD,Morrison AR,Ball WA,Ross RJ,Mann GL

    更新日期:1992-12-01 00:00:00

  • A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.

    abstract::Rapid eye movement (REM) sleep behaviour disorder (RBD) has been suggested to predict the development of neurodegenerative disorders. Patients with RBD are acting out dream behaviour associated with loss of normal muscle atonia of REM sleep. The aim of the present study was to confirm that exogenous melatonin improves...

    journal_title:Journal of sleep research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2869.2010.00848.x

    authors: Kunz D,Mahlberg R

    更新日期:2010-12-01 00:00:00

  • The incidence and temporal patterning of insomnia: a pilot study.

    abstract::To date very little research has been conducted on night-to-night variability in the incidence of insomnia. It is unclear from prior research whether subjects with primary insomnia (PI) exhibit good sleep (or better than average sleep) on some interval basis. In the present study, pilot data are provided on: (1) the f...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2009.00768.x

    authors: Perlis ML,Swinkels CM,Gehrman PR,Pigeon WR,Matteson-Rusby SE,Jungquist CR

    更新日期:2010-03-01 00:00:00

  • Multi-centre comparison of five eye movement detection algorithms.

    abstract::Although various investigators have suggested algorithms for the automatic detection of eye movements during sleep, objective comparisons of the proposed methods have previously been difficult due to different recording arrangements of different investigators. In this study the results of five eye movement detection a...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:

    authors: Värri A,Kemp B,Rosa AC,Nielsen KD,Gade J,Penzel T,Hasan J,Hirvonen K,Häkkinen V V,Kamphuisen HA,Mourtazaev MS

    更新日期:1995-06-01 00:00:00

  • Association between polysomnographic sleep measures and health-related quality of life in obstructive sleep apnea.

    abstract::Many facets of health-related quality of life are diminished in obstructive sleep apnea (OSA) as they are in other chronic medical conditions. We speculated that impairment in health-related quality of life (HRQoL) might result from the fatigue and daytime somnolence associated with the sleep disorder, as an indirect ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1046/j.1365-2869.2001.00264.x

    authors: Moore P,Bardwell WA,Ancoli-Israel S,Dimsdale JE

    更新日期:2001-12-01 00:00:00

  • Stimulus-induced brain lactate: effects of aging and prolonged wakefulness.

    abstract::Both aging and sleep deprivation disturb the functions of the frontal lobes. Deficits in brain energy metabolism have been reported in these conditions. Neurons use not only glucose but also lactate as their energy substrate. The physiological response to elevated neuronal activity is a transient increase in lactate c...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2004.00401.x

    authors: Urrila AS,Hakkarainen A,Heikkinen S,Vuori K,Stenberg D,Häkkinen AM,Lundbom N,Porkka-Heiskanen T

    更新日期:2004-06-01 00:00:00

  • Functional magnetic resonance imaging neuroactivation studies in normal subjects and subjects with the narcoleptic syndrome. Actions of modafinil.

    abstract::Functional magnetic resonance imaging (fMRI) can be used to detect regional brain responses to changes in sensory stimuli. We have used fMRI to determine the amount of visual and auditory cortical activation in 12 normal subjects and 12 subjects with the narcoleptic syndrome, using a multiplexed visual and auditory st...

    journal_title:Journal of sleep research

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1365-2869.1999.00142.x

    authors: Ellis CM,Monk C,Simmons A,Lemmens G,Williams SC,Brammer M,Bullmore E,Parkes JD

    更新日期:1999-06-01 00:00:00

  • Genetic factors in evolution of sleep length--a longitudinal twin study in Finnish adults.

    abstract::Genetic factors affect many aspects of sleep, such as sleep length. We investigated the contribution of genetic factors to stability and change of sleep length among adults over a 15-year period. In this representative follow-up study we used the Finnish Twin Cohort as the study population. Questionnaire surveys were ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12051

    authors: Hublin C,Partinen M,Koskenvuo M,Kaprio J

    更新日期:2013-10-01 00:00:00

  • The meaning of good sleep: a longitudinal study of polysomnography and subjective sleep quality.

    abstract::The present study sought to investigate the meaning of subjectively good sleep, using a longitudinal and intraindividual design. Eight subjects slept in an isolation unit according to an irregular schedule of 6 h sleeps and 1 h naps, designed to give normal amounts of time in bed (1/3 of total), but variable sleep qua...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.1994.tb00122.x

    authors: Åkerstedt T,Hume K,Minors D,Waterhouse J

    更新日期:1994-09-01 00:00:00

  • A new likelihood ratio metric for the psychomotor vigilance test and its sensitivity to sleep loss.

    abstract::The Psychomotor Vigilance Test (PVT) is a widely used assay of behavioural alertness sensitive to the effects of sleep loss and circadian misalignment. However, there is currently no accepted PVT composite outcome metric that captures response slowing, attentional lapses and compensatory premature reactions observed t...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12322

    authors: Basner M,Mcguire S,Goel N,Rao H,Dinges DF

    更新日期:2015-12-01 00:00:00

  • Heart rate variability during sleep in children with partial epilepsy.

    abstract::Alterations in autonomic control of cardiac activity in epileptic patients have been reported by several studies in the past, and both ictal and interictal modifications of heart rate regulation have been described. Alterations of autonomic control of cardiac activity can play an important role in sudden unexplained d...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1046/j.1365-2869.2002.00283.x

    authors: Ferri R,Curzi-Dascalova L,Arzimanoglou A,Bourgeois M,Beaud C,Nunes ML,Elia M,Musumeci SA,Tripodi M

    更新日期:2002-06-01 00:00:00

  • Random number generation during sleep deprivation: effects of caffeine on response maintenance and stereotypy.

    abstract::Neurophysiological and functional imaging studies have demonstrated that frontal regions of the brain are particularly responsive to homeostatic sleep pressure. Previous neuropsychological studies indicate that sleep deprivation causes impairments in prefrontal cortical function. Random number generation (RNG) is thou...

    journal_title:Journal of sleep research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2869.2006.00497.x

    authors: Gottselig JM,Adam M,Rétey JV,Khatami R,Achermann P,Landolt HP

    更新日期:2006-03-01 00:00:00

  • Effect of low and high frequency thalamic stimulation on sleep in patients with Parkinson's disease and essential tremor.

    abstract::Continuous high frequency stimulation of the ventral intermediate nucleus of the thalamus (Vim), delivered through surgically implanted quadripolar electrodes, alleviates tremor in Parkinson's disease (PD) and essential tremor (ET). The Vim is adjacent to the thalamic reticular nuclei, where sleep spindles originate a...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1046/j.1365-2869.2000.00171.x

    authors: Arnulf I,Bejjani BP,Garma L,Bonnet AM,Damier P,Pidoux B,Dormont D,Cornu P,Derenne JP,Agid Y

    更新日期:2000-03-01 00:00:00

  • The nature of arousal in sleep.

    abstract::The role of arousals in sleep is gaining interest among both basic researchers and clinicians. In the last 20 years increasing evidence shows that arousals are deeply involved in the pathophysiology of sleep disorders. The nature of arousals in sleep is still a matter of debate. According to the conceptual framework o...

    journal_title:Journal of sleep research

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2869.2004.00388.x

    authors: Halász P,Terzano M,Parrino L,Bódizs R

    更新日期:2004-03-01 00:00:00

  • Sleep inhibition induced by amyloid-β oligomers is mediated by the cellular prion protein.

    abstract::Sleep is severely impaired in patients with Alzheimer's disease. Amyloid-β deposition in the brain of Alzheimer's disease patients is a key event in its pathogenesis and is associated with disrupted sleep, even before the appearance of cognitive decline. Because soluble amyloid-β oligomers are the key mediators of syn...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.13187

    authors: Del Gallo F,Bianchi S,Bertani I,Messa M,Colombo L,Balducci C,Salmona M,Imeri L,Chiesa R

    更新日期:2020-09-09 00:00:00

  • Investigation of sleep spindle activity and morphology as predictors of neurocognitive functioning in medicated patients with schizophrenia.

    abstract::Neurocognitive impairment is a trait marker of schizophrenia, but no effective treatment has yet been identified. Sleep spindle deficits have been associated with diminished sleep-dependent memory learning. We examined whether this link could be extended into various cognitive domains by investigating the association ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12672

    authors: Baandrup L,Christensen JAE,Fagerlund B,Jennum P

    更新日期:2019-02-01 00:00:00

  • Interleukin 6 as a marker of depression in women with sleep apnea.

    abstract::Depression is common in women with obstructive sleep apnea (OSA), but objective markers of depression have not yet been explored in such patients. We hypothesized that inflammation and antioxidant biomarkers may be associated with depression in a cohort of OSA women. We conducted a multicentre, cross-sectional study i...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.13035

    authors: Campos-Rodriguez F,Cordero-Guevara J,Asensio-Cruz MI,Sanchez-Armengol A,Sanchez-Lopez V,Arellano-Orden E,Gozal D,Martinez-Garcia MA

    更新日期:2021-02-01 00:00:00

  • Systematic decrease of slow-wave sleep after a guided imagery designed to deepen sleep in low hypnotizable subjects.

    abstract::Slow-wave sleep is one of the most important restorative components of sleep and central for our health and cognitive functioning. Although the amount of slow-wave sleep depends on sleep drive, age and other factors, also the pre-sleep mental state might influence sleep depth. We had shown that a pre-sleep hypnotic su...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.13168

    authors: Cordi MJ,Rasch B

    更新日期:2020-08-17 00:00:00

  • Sleep related rhythmic movement disorder revisited.

    abstract::To classify sleep related rhythmic movement disorder (SRMD) based on clinical, polysomnographic and videometric evaluation in a predominantly adult population, twenty-four patients (four females) aged 11-67 years identified by polysomnography and videometry were classified for type of SRMD, its duration and frequency ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2007.00577.x

    authors: Mayer G,Wilde-Frenz J,Kurella B

    更新日期:2007-03-01 00:00:00

  • Are patients with chronic fatigue syndrome just 'tired' or also 'sleepy'?

    abstract::It is presently unclear whether chronic fatigue syndrome (CFS) patients exhibit daytime sleepiness in addition to fatigue. Both, fatigue, such as that seen in CFS patients, and excessive daytime sleepiness, such as in sleep apnea-hypopnea syndrome (SAHS), remain poorly understood. Both daytime conditions are generally...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2008.00679.x

    authors: Neu D,Hoffmann G,Moutrier R,Verbanck P,Linkowski P,Le Bon O

    更新日期:2008-12-01 00:00:00

  • Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.

    abstract::Stimulants may provide short-term performance and alertness enhancement during sleep loss. Caffeine 600 mg, d-amphetamine 20 mg, and modafinil 400 mg were compared during 85 h of total sleep deprivation to determine the extent to which the three agents restored performance on simple psychomotor tasks, objective alertn...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2005.00468.x

    authors: Wesensten NJ,Killgore WD,Balkin TJ

    更新日期:2005-09-01 00:00:00

  • Molecular approaches towards the isolation of sleep-related genes.

    abstract::Behavioural genetics is one of the most enticing fields in modern biology. Owing to straightforward and semiautomated techniques that can be used to measure locomotor activity, circadian rhythmicity is perhaps the best studied behaviour in animals. Thus, during the past decade, five essential circadian clock genes hav...

    journal_title:Journal of sleep research

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2869.1999.00001.x

    authors: Schibler U,Tafti M

    更新日期:1999-06-01 00:00:00

  • Changes in sleepiness and body temperature precede nocturnal sleep onset: evidence from a polysomnographic study in young men.

    abstract::Recent research has shown a close temporal relationship between the nocturnal decrease in rectal core temperature and the initiation of sleep. However, there is not yet a clear temporal relationship between changes in peripheral and core temperatures and nocturnal sleep onset. We recorded body temperatures in 14 adult...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1046/j.1365-2869.1998.00112.x

    authors: van den Heuvel CJ,Noone JT,Lushington K,Dawson D

    更新日期:1998-09-01 00:00:00

  • Decreased body mass index during treatment with sodium oxybate in narcolepsy type 1.

    abstract::Narcolepsy type 1 is characterised by an increase in body weight after disease onset, frequently leading to obesity. It was suggested that this weight gain may be counteracted by treatment with sodium oxybate. We here provide longitudinal body mass index data of patients with narcolepsy type 1 after starting treatment...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12684

    authors: Schinkelshoek MS,Smolders IM,Donjacour CE,van der Meijden WP,van Zwet EW,Fronczek R,Lammers GJ

    更新日期:2019-06-01 00:00:00

  • Sleep, health and memory: comparing parents of typically developing children and parents of children with special health-care needs.

    abstract::Parents of children with special healthcare needs (CSHCNs) report poorer sleep than parents of typically developing (TD) children, which has been associated with poorer mental health. The relations between sleep disturbances and general health and memory among this population are unknown. The current study aimed to re...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12329

    authors: Mcbean AL,Schlosnagle L

    更新日期:2016-02-01 00:00:00

  • Month of birth is not a risk factor for narcolepsy with cataplexy in the Netherlands.

    abstract::The month of birth has been proposed as a risk factor for narcolepsy, suggesting a harmful influence during early development. Several authors have described an excess of births in March in those developing narcolepsy later. Analysis methods in published studies varied, but no study corrected completely for possible c...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2011.00933.x

    authors: Donjacour CE,Fronczek R,LE Cessie S,Lammers GJ,VAN Dijk JG

    更新日期:2011-12-01 00:00:00

  • Sleep duration and mortality - Does weekend sleep matter?

    abstract::Previous studies have found a U-shaped relationship between mortality and (weekday) sleep duration. We here address the association of both weekday and weekend sleep duration with overall mortality. A cohort of 43,880 subjects was followed for 13 years through record-linkages. Cox proportional hazards regression model...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12712

    authors: Åkerstedt T,Ghilotti F,Grotta A,Zhao H,Adami HO,Trolle-Lagerros Y,Bellocco R

    更新日期:2019-02-01 00:00:00

  • Objectively measured night-to-night sleep variations are associated with body composition in very elderly women.

    abstract::This cross-sectional study examined the association between objectively measured sleep patterns and body composition in very elderly community-dwelling women. Participants included 191 community-dwelling adults aged ≥ 80 years (mean age: 83.4 ± 2.6 years; age range: 80-92 years). Sleep and physical activity were monit...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12326

    authors: Kim M,Sasai H,Kojima N,Kim H

    更新日期:2015-12-01 00:00:00

  • Effects of signal artefacts on electroencephalography spectral power during sleep: quantifying the effectiveness of automated artefact-rejection algorithms.

    abstract::Electroencephalography (EEG) recordings during sleep are often contaminated by muscle and ocular artefacts, which can affect the results of spectral power analyses significantly. However, the extent to which these artefacts affect EEG spectral power across different sleep states has not been quantified explicitly. Con...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12576

    authors: Liu J,Ramakrishnan S,Laxminarayan S,Neal M,Cashmere DJ,Germain A,Reifman J

    更新日期:2018-02-01 00:00:00