Abstract:
:Activity-rest patterns displayed by an animal under various circumstances are suggested to result from the combined influences of two virtually identical circadian pacemaker components. Increased output of each component proportionally increases the probability of activity of the animal. Such a dual circadian pacemaker model explains much of the phenomenology of activity-rest records. Under normal light-dark schedules, the two components of the model have a similar phase relationship to the Zeitgeber. Differential synchronization of the components to dawn and dusk is not assumed.
journal_name
J Sleep Resjournal_title
Journal of sleep researchauthors
Beersma DG,Daan Sdoi
10.1111/j.1365-2869.1992.tb00015.xsubject
Has Abstractpub_date
1992-06-01 00:00:00pages
84-87issue
2eissn
0962-1105issn
1365-2869pii
jsr001002084journal_volume
1pub_type
杂志文章abstract::Cognitive performance is impaired by fatigue arising from sustained wakefulness and alcohol. Three recent papers directly compared the effects of increasing fatigue and blood alcohol concentration (%BAC) to provide a framework for understanding fatigue-related cognitive impairment. While the expression of fatigue-rela...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/j.1365-2869.2004.00438.x
更新日期:2005-03-01 00:00:00
abstract::Ponto-geniculo-occipital (PGO) waves are spontaneously-occurring macropotential waveforms recorded in the pons, lateral geniculate body (LGB) and occipital cortex. PGO waves mark the onset and course of rapid eye movement sleep (REM). PGO-like waves can be recorded in several brain areas including the thalamic central...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/j.1365-2869.1992.tb00048.x
更新日期:1992-12-01 00:00:00
abstract::Rapid eye movement (REM) sleep behaviour disorder (RBD) has been suggested to predict the development of neurodegenerative disorders. Patients with RBD are acting out dream behaviour associated with loss of normal muscle atonia of REM sleep. The aim of the present study was to confirm that exogenous melatonin improves...
journal_title:Journal of sleep research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2869.2010.00848.x
更新日期:2010-12-01 00:00:00
abstract::To date very little research has been conducted on night-to-night variability in the incidence of insomnia. It is unclear from prior research whether subjects with primary insomnia (PI) exhibit good sleep (or better than average sleep) on some interval basis. In the present study, pilot data are provided on: (1) the f...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/j.1365-2869.2009.00768.x
更新日期:2010-03-01 00:00:00
abstract::Although various investigators have suggested algorithms for the automatic detection of eye movements during sleep, objective comparisons of the proposed methods have previously been difficult due to different recording arrangements of different investigators. In this study the results of five eye movement detection a...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00
abstract::Many facets of health-related quality of life are diminished in obstructive sleep apnea (OSA) as they are in other chronic medical conditions. We speculated that impairment in health-related quality of life (HRQoL) might result from the fatigue and daytime somnolence associated with the sleep disorder, as an indirect ...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1046/j.1365-2869.2001.00264.x
更新日期:2001-12-01 00:00:00
abstract::Both aging and sleep deprivation disturb the functions of the frontal lobes. Deficits in brain energy metabolism have been reported in these conditions. Neurons use not only glucose but also lactate as their energy substrate. The physiological response to elevated neuronal activity is a transient increase in lactate c...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/j.1365-2869.2004.00401.x
更新日期:2004-06-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) can be used to detect regional brain responses to changes in sensory stimuli. We have used fMRI to determine the amount of visual and auditory cortical activation in 12 normal subjects and 12 subjects with the narcoleptic syndrome, using a multiplexed visual and auditory st...
journal_title:Journal of sleep research
pub_type: 临床试验,杂志文章
doi:10.1046/j.1365-2869.1999.00142.x
更新日期:1999-06-01 00:00:00
abstract::Genetic factors affect many aspects of sleep, such as sleep length. We investigated the contribution of genetic factors to stability and change of sleep length among adults over a 15-year period. In this representative follow-up study we used the Finnish Twin Cohort as the study population. Questionnaire surveys were ...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/jsr.12051
更新日期:2013-10-01 00:00:00
abstract::The present study sought to investigate the meaning of subjectively good sleep, using a longitudinal and intraindividual design. Eight subjects slept in an isolation unit according to an irregular schedule of 6 h sleeps and 1 h naps, designed to give normal amounts of time in bed (1/3 of total), but variable sleep qua...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/j.1365-2869.1994.tb00122.x
更新日期:1994-09-01 00:00:00
abstract::The Psychomotor Vigilance Test (PVT) is a widely used assay of behavioural alertness sensitive to the effects of sleep loss and circadian misalignment. However, there is currently no accepted PVT composite outcome metric that captures response slowing, attentional lapses and compensatory premature reactions observed t...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/jsr.12322
更新日期:2015-12-01 00:00:00
abstract::Alterations in autonomic control of cardiac activity in epileptic patients have been reported by several studies in the past, and both ictal and interictal modifications of heart rate regulation have been described. Alterations of autonomic control of cardiac activity can play an important role in sudden unexplained d...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1046/j.1365-2869.2002.00283.x
更新日期:2002-06-01 00:00:00
abstract::Neurophysiological and functional imaging studies have demonstrated that frontal regions of the brain are particularly responsive to homeostatic sleep pressure. Previous neuropsychological studies indicate that sleep deprivation causes impairments in prefrontal cortical function. Random number generation (RNG) is thou...
journal_title:Journal of sleep research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2869.2006.00497.x
更新日期:2006-03-01 00:00:00
abstract::Continuous high frequency stimulation of the ventral intermediate nucleus of the thalamus (Vim), delivered through surgically implanted quadripolar electrodes, alleviates tremor in Parkinson's disease (PD) and essential tremor (ET). The Vim is adjacent to the thalamic reticular nuclei, where sleep spindles originate a...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1046/j.1365-2869.2000.00171.x
更新日期:2000-03-01 00:00:00
abstract::The role of arousals in sleep is gaining interest among both basic researchers and clinicians. In the last 20 years increasing evidence shows that arousals are deeply involved in the pathophysiology of sleep disorders. The nature of arousals in sleep is still a matter of debate. According to the conceptual framework o...
journal_title:Journal of sleep research
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2869.2004.00388.x
更新日期:2004-03-01 00:00:00
abstract::Sleep is severely impaired in patients with Alzheimer's disease. Amyloid-β deposition in the brain of Alzheimer's disease patients is a key event in its pathogenesis and is associated with disrupted sleep, even before the appearance of cognitive decline. Because soluble amyloid-β oligomers are the key mediators of syn...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/jsr.13187
更新日期:2020-09-09 00:00:00
abstract::Neurocognitive impairment is a trait marker of schizophrenia, but no effective treatment has yet been identified. Sleep spindle deficits have been associated with diminished sleep-dependent memory learning. We examined whether this link could be extended into various cognitive domains by investigating the association ...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/jsr.12672
更新日期:2019-02-01 00:00:00
abstract::Depression is common in women with obstructive sleep apnea (OSA), but objective markers of depression have not yet been explored in such patients. We hypothesized that inflammation and antioxidant biomarkers may be associated with depression in a cohort of OSA women. We conducted a multicentre, cross-sectional study i...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/jsr.13035
更新日期:2021-02-01 00:00:00
abstract::Slow-wave sleep is one of the most important restorative components of sleep and central for our health and cognitive functioning. Although the amount of slow-wave sleep depends on sleep drive, age and other factors, also the pre-sleep mental state might influence sleep depth. We had shown that a pre-sleep hypnotic su...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/jsr.13168
更新日期:2020-08-17 00:00:00
abstract::To classify sleep related rhythmic movement disorder (SRMD) based on clinical, polysomnographic and videometric evaluation in a predominantly adult population, twenty-four patients (four females) aged 11-67 years identified by polysomnography and videometry were classified for type of SRMD, its duration and frequency ...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/j.1365-2869.2007.00577.x
更新日期:2007-03-01 00:00:00
abstract::It is presently unclear whether chronic fatigue syndrome (CFS) patients exhibit daytime sleepiness in addition to fatigue. Both, fatigue, such as that seen in CFS patients, and excessive daytime sleepiness, such as in sleep apnea-hypopnea syndrome (SAHS), remain poorly understood. Both daytime conditions are generally...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/j.1365-2869.2008.00679.x
更新日期:2008-12-01 00:00:00
abstract::Stimulants may provide short-term performance and alertness enhancement during sleep loss. Caffeine 600 mg, d-amphetamine 20 mg, and modafinil 400 mg were compared during 85 h of total sleep deprivation to determine the extent to which the three agents restored performance on simple psychomotor tasks, objective alertn...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/j.1365-2869.2005.00468.x
更新日期:2005-09-01 00:00:00
abstract::Behavioural genetics is one of the most enticing fields in modern biology. Owing to straightforward and semiautomated techniques that can be used to measure locomotor activity, circadian rhythmicity is perhaps the best studied behaviour in animals. Thus, during the past decade, five essential circadian clock genes hav...
journal_title:Journal of sleep research
pub_type: 杂志文章,评审
doi:10.1046/j.1365-2869.1999.00001.x
更新日期:1999-06-01 00:00:00
abstract::Recent research has shown a close temporal relationship between the nocturnal decrease in rectal core temperature and the initiation of sleep. However, there is not yet a clear temporal relationship between changes in peripheral and core temperatures and nocturnal sleep onset. We recorded body temperatures in 14 adult...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1046/j.1365-2869.1998.00112.x
更新日期:1998-09-01 00:00:00
abstract::Narcolepsy type 1 is characterised by an increase in body weight after disease onset, frequently leading to obesity. It was suggested that this weight gain may be counteracted by treatment with sodium oxybate. We here provide longitudinal body mass index data of patients with narcolepsy type 1 after starting treatment...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/jsr.12684
更新日期:2019-06-01 00:00:00
abstract::Parents of children with special healthcare needs (CSHCNs) report poorer sleep than parents of typically developing (TD) children, which has been associated with poorer mental health. The relations between sleep disturbances and general health and memory among this population are unknown. The current study aimed to re...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/jsr.12329
更新日期:2016-02-01 00:00:00
abstract::The month of birth has been proposed as a risk factor for narcolepsy, suggesting a harmful influence during early development. Several authors have described an excess of births in March in those developing narcolepsy later. Analysis methods in published studies varied, but no study corrected completely for possible c...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/j.1365-2869.2011.00933.x
更新日期:2011-12-01 00:00:00
abstract::Previous studies have found a U-shaped relationship between mortality and (weekday) sleep duration. We here address the association of both weekday and weekend sleep duration with overall mortality. A cohort of 43,880 subjects was followed for 13 years through record-linkages. Cox proportional hazards regression model...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/jsr.12712
更新日期:2019-02-01 00:00:00
abstract::This cross-sectional study examined the association between objectively measured sleep patterns and body composition in very elderly community-dwelling women. Participants included 191 community-dwelling adults aged ≥ 80 years (mean age: 83.4 ± 2.6 years; age range: 80-92 years). Sleep and physical activity were monit...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/jsr.12326
更新日期:2015-12-01 00:00:00
abstract::Electroencephalography (EEG) recordings during sleep are often contaminated by muscle and ocular artefacts, which can affect the results of spectral power analyses significantly. However, the extent to which these artefacts affect EEG spectral power across different sleep states has not been quantified explicitly. Con...
journal_title:Journal of sleep research
pub_type: 杂志文章
doi:10.1111/jsr.12576
更新日期:2018-02-01 00:00:00