Abstract:
:Behavioural genetics is one of the most enticing fields in modern biology. Owing to straightforward and semiautomated techniques that can be used to measure locomotor activity, circadian rhythmicity is perhaps the best studied behaviour in animals. Thus, during the past decade, five essential circadian clock genes have been isolated in Drosophila, and homologous counterparts for all of these genes have also been found in mammals. As the sleep-wake cycle is under the control of the circadian clock, these circadian master genes are expected to influence sleeping behaviour. However, different vigilance states are regulated by additional mechanisms that also have a genetic basis. In this article we discuss molecular approaches that may prove useful in the search for sleep-related genes.
journal_name
J Sleep Resjournal_title
Journal of sleep researchauthors
Schibler U,Tafti Mdoi
10.1046/j.1365-2869.1999.00001.xsubject
Has Abstractpub_date
1999-06-01 00:00:00pages
1-10eissn
0962-1105issn
1365-2869journal_volume
8 Suppl 1pub_type
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journal_title:Journal of sleep research
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journal_title:Journal of sleep research
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journal_title:Journal of sleep research
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journal_title:Journal of sleep research
pub_type: 杂志文章
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journal_title:Journal of sleep research
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journal_title:Journal of sleep research
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journal_title:Journal of sleep research
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Journal of sleep research
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journal_title:Journal of sleep research
pub_type: 杂志文章
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更新日期:2020-12-01 00:00:00
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journal_title:Journal of sleep research
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Journal of sleep research
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journal_title:Journal of sleep research
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journal_title:Journal of sleep research
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journal_title:Journal of sleep research
pub_type: 杂志文章
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journal_title:Journal of sleep research
pub_type: 杂志文章,评审
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