Association between irritable bowel syndrome and restless legs syndrome in the general population.

Abstract:

:This study aimed to explore the association between restless legs syndrome and irritable bowel syndrome in an epidemiological cohort. We included 3365 adults, of whom 1602 were female (age 52.5 ± 7.5 years), who had participated in the Korean Genome and Epidemiology Study (2005-2006). The diagnosis of restless legs syndrome was based on the criteria proposed by the International Restless Legs Syndrome Study Group, and irritable bowel syndrome was defined according to the Rome II criteria. The prevalence of each condition was determined and their association was tested by logistic regression analysis. Age, sex, haemoglobin concentration, renal insufficiency, use of medications and depressive mood were all adjusted for. The prevalence of restless legs syndrome and irritable bowel syndrome was 4.5 and 11.1%, respectively. Irritable bowel syndrome was more prevalent in the group with restless legs syndrome (24.0 versus 10.5%, P < 0.001). Subjects with restless legs syndrome were older (54.2 ± 8.4 versus 52.4 ± 7.4, P = 0.006) and more depressive (26.7 versus 12.5%, P < 0.001), and were predominantly female (57.3 versus 47.2%, P = 0.015), had more frequent insomnia symptoms (44.0 versus 28.2%, P < 0.001), had lower haemoglobin concentration (13.7 ± 1.5 versus 14.1 ± 1.6 g dL(-1) P = 0.004) and higher highly sensitive C-reactive protein (1.8 ± 5.1 versus 1.4 ± 2.9 mg dL(-1), P = 0.08). The adjusted odds ratio of restless legs syndrome in relation to irritable bowel syndrome was 2.59 (1.74-3.85, P < 0.001). Irritable bowel syndrome appeared to be associated with restless legs syndrome independently from other major risk factors for restless legs syndrome. Searching for the mechanisms underlying this association is indicated.

journal_name

J Sleep Res

authors

Yun CH,Lee SK,Kim H,Park HK,Lee SH,Kim SJ,Shin C

doi

10.1111/j.1365-2869.2012.01011.x

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

569-76

issue

5

eissn

0962-1105

issn

1365-2869

journal_volume

21

pub_type

杂志文章
  • Sleep patterns of European expatriates in a dry tropical climate.

    abstract::Night sleep in sedentary African subjects living in the sahelian zone lasts from 7 h to 8 h, with high amounts of slow-wave sleep (SWS) and paradoxical sleep (PS), SWS being present in each sleep cycle. We report here on sleep patterns in 6 healthy male European expatriates (aged 32-39 years) living in the same tropic...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.1992.tb00037.x

    authors: Montmayeur A,Buguet A

    更新日期:1992-09-01 00:00:00

  • Copulatory activity increases slow-wave sleep in the male rat.

    abstract::It is believed that sexual activity increases the need to sleep in many species. However, the relationship between copulatory activity and sleep has been poorly studied. Several studies have observed variations in the sleep of female rats and women as a function of their reproductive state. These effects have been cor...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1046/j.1365-2869.2002.00304.x

    authors: Vazquez-Palacios G,Bonilla-Jaime H,Retana-Marquez S,Velazquez-Moctezuma J

    更新日期:2002-09-01 00:00:00

  • Emotional facial expressions during REM sleep dreams.

    abstract::Although motor activity is actively inhibited during rapid eye movement (REM) sleep, specific activations of the facial mimetic musculature have been observed during this stage, which may be associated with greater emotional dream mentation. Nevertheless, no specific biomarker of emotional valence or arousal related t...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12716

    authors: Rivera-García AP,López Ruiz IE,Ramírez-Salado I,González-Olvera JJ,Ayala-Guerrero F,Jiménez-Anguiano A

    更新日期:2019-02-01 00:00:00

  • Circadian motor activity affected by stimulant medication in children with attention-deficit/hyperactivity disorder.

    abstract::Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent disorder occurring in approximately 3-5% of school-aged children. The core symptoms of ADHD are effectively treated with stimulant medications such as methylphenidate; however, there are also negative side effects, including insomnia. It has been su...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2010.00845.x

    authors: Ironside S,Davidson F,Corkum P

    更新日期:2010-12-01 00:00:00

  • Effects of a short midday nap on habitual nappers' alertness, mood and mental performance across cognitive domains.

    abstract::This study examines whether the benefits of a short midday nap on habitual nappers' mental performance depend on the cognitive domain and the task difficulty. Eighteen healthy college students with the long-term habit of a midday nap (13:00-14:00 hours) participated in a nap-deprivation study. On two separate days wit...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12638

    authors: Ru T,Chen Q,You J,Zhou G

    更新日期:2019-06-01 00:00:00

  • Exercise and sleep in community-dwelling older adults: evidence for a reciprocal relationship.

    abstract::Exercise behaviour and sleep are both important health indicators that demonstrate significant decreases with age, and remain modifiable well into later life. The current investigation examined both the chronic and acute relationships between exercise behaviour and self-reported sleep in older adults through a seconda...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12078

    authors: Dzierzewski JM,Buman MP,Giacobbi PR Jr,Roberts BL,Aiken-Morgan AT,Marsiske M,McCrae CS

    更新日期:2014-02-01 00:00:00

  • Intermediate phenotypes of childhood obstructive sleep apnea.

    abstract::An intermediate phenotype of a disease is a trait in the path of pathogenesis from genetic predisposition to disease manifestation. Identifying intermediate phenotypes with high heritability is helpful in delineating the genetics of a disorder. In this study, we aimed to examine various traits with regards to obesity,...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.13191

    authors: Au CT,Chan KC,Zhang J,Liu KH,Chu WCW,Wing YK,Li AM

    更新日期:2020-09-14 00:00:00

  • Aniridia with PAX6 mutations and narcolepsy.

    abstract::PAX6 gene mutations cause a variety of eye and central nervous system (CNS) abnormalities. Aniridia is often accompanied by CNS abnormalities such as pineal gland atrophy or hypoplasia, leading to disturbed circadian rhythm and sleep disorders. Less is known on the coincidence of narcolepsy in this patient group. We a...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12982

    authors: Berntsson SG,Kristoffersson A,Daniilidou M,Dahl N,Ekström C,Semnic R,Markström A,Niemelä V,Partinen M,Hallböök F,Landtblom AM

    更新日期:2020-12-01 00:00:00

  • Sleep in the harp seal (Pagophilus groenlandica). Comparison of sleep on land and in water.

    abstract::Four young harp seals (aged three to five months) were implanted with electrodes for recording electrocorticograms (ECoG) of the two hemispheres, and electrocardiogram, electroculogram, and electromyogram of the neck muscles. In all the seals ECoG slow waves developed simultaneously in both hemispheres, irrespective o...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.1993.tb00082.x

    authors: Lyamin OI

    更新日期:1993-09-01 00:00:00

  • The effect of anticipatory stress and openness and engagement on subsequently perceived sleep quality-An Experience Sampling Method study.

    abstract::High stress levels can influence sleep quality negatively. If this also applies to anticipatory stress is poorly documented, however. Across insomnia severity levels, this study examined participants' evening levels of (a) anticipatory stress and (b) their skills hypothesized to downregulate the impact of stress, name...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12957

    authors: Block VJ,Meyer AH,Miché M,Mikoteit T,Hoyer J,Imboden C,Bader K,Hatzinger M,Lieb R,Gloster AT

    更新日期:2020-10-01 00:00:00

  • Reestablishment of individual sleep structure during a single 14-h recovery sleep episode after 58 h of wakefulness.

    abstract::Sleep structure is highly stable within individuals but different between individuals. The present study investigated robustness of the individual sleep structure to extended total sleep deprivation. Seventeen healthy men spent a baseline night (23:00-07:00 hours), 58 h of sleep deprivation and a 14-h recovery night (...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12641

    authors: Hennecke E,Elmenhorst D,Mendolia F,Putzke M,Bauer A,Aeschbach D,Elmenhorst EM

    更新日期:2019-06-01 00:00:00

  • Sleep propensity and sleep architecture after bright light exposure at three different times of day.

    abstract::The aim of this work was to study the effects of bright light-induced circadian phase shifts on sleep propensity and sleep architecture while the timing of the sleep/wake cycle is kept constant. Twenty-three normal subjects underwent an 11-day study including: (i) baseline sleep and vigilance evaluation; (ii) baseline...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.1995.tb00171.x

    authors: Carrier J,Dumont M

    更新日期:1995-12-01 00:00:00

  • Effects of sleep modulation during pregnancy in the mother and offspring: Evidences from preclinical research.

    abstract::Disturbed sleep during gestation may lead to adverse outcomes for both mother and child. Animal research plays an important role in providing insights into this research field by enabling ethical and methodological requirements that are not possible in humans. Here, we present an overview and discuss the main research...

    journal_title:Journal of sleep research

    pub_type: 杂志文章,评审

    doi:10.1111/jsr.13135

    authors: Pires GN,Benedetto L,Cortese R,Gozal D,Gulia KK,Kumar VM,Tufik S,Andersen ML

    更新日期:2020-07-02 00:00:00

  • Generation of activity-rest patterns by dual circadian pacemaker systems: a model.

    abstract::Activity-rest patterns displayed by an animal under various circumstances are suggested to result from the combined influences of two virtually identical circadian pacemaker components. Increased output of each component proportionally increases the probability of activity of the animal. Such a dual circadian pacemake...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.1992.tb00015.x

    authors: Beersma DG,Daan S

    更新日期:1992-06-01 00:00:00

  • Feasibility, acceptability and affective consequences of at-home sleep extension in young women with depressive symptoms: A pilot study.

    abstract::Insufficient sleep is common in young adults and has meaningful consequences for daytime functioning, including increased sleepiness, affective disruption and depressive symptoms. This study provides a preliminary evaluation of the feasibility, acceptability and affective consequences of extended sleep opportunity in ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.13045

    authors: Casement MD,Livingston NR,Allen NB,Forbes EE

    更新日期:2020-05-28 00:00:00

  • Effect of ambient temperature on arterial pressure variability during sleep in the rat.

    abstract::Changes in mean arterial pressure (MAP) and heart rate (HR) during sleep were recorded at three ambient temperatures (Ta: 16, 22 and 28 degrees C). MAP and HR during sleep increased with lowering of Ta. The increase in MAP during the transition from NREM to REM sleep was decreased by lowering the Ta. At 28 degrees C, ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1046/j.1365-2869.1996.00007.x

    authors: Sei H,Morita Y

    更新日期:1996-03-01 00:00:00

  • High-altitude hypoxia and periodic breathing during sleep: gender-related differences.

    abstract::High-altitude exposure is characterized by the appearance of periodic breathing during sleep. Only limited evidence is available, however, on the presence of gender-related differences in this breathing pattern. In 37 healthy subjects, 23 male and 14 female, we performed nocturnal cardio-respiratory monitoring in the ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/jsr.12012

    authors: Lombardi C,Meriggi P,Agostoni P,Faini A,Bilo G,Revera M,Caldara G,Di Rienzo M,Castiglioni P,Maurizio B,Gregorini F,Mancia G,Parati G,HIGHCARE Investigators.

    更新日期:2013-06-01 00:00:00

  • The meaning of good sleep: a longitudinal study of polysomnography and subjective sleep quality.

    abstract::The present study sought to investigate the meaning of subjectively good sleep, using a longitudinal and intraindividual design. Eight subjects slept in an isolation unit according to an irregular schedule of 6 h sleeps and 1 h naps, designed to give normal amounts of time in bed (1/3 of total), but variable sleep qua...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.1994.tb00122.x

    authors: Åkerstedt T,Hume K,Minors D,Waterhouse J

    更新日期:1994-09-01 00:00:00

  • The dynamic relationship between daily caffeine intake and sleep duration in middle-aged and older adults.

    abstract::The effect of caffeine on sleep has been well documented. However, most studies examined this relationship in laboratories or used a cross-sectional design analysing between-person differences. This study investigated the within-person relationship between caffeine intake and sleep duration at home. In a national data...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12996

    authors: Hu Y,Stephenson K,Klare D

    更新日期:2020-12-01 00:00:00

  • The effect of complex cognitive training on subsequent night sleep.

    abstract::Using a nap design, we have recently shown that training at a complex cognitive task at bedtime improves objective sleep quality by reducing sleep fragmentation. In order to extend our findings to nighttime sleep, here we assess the impact of a multi-componential cognitive task at bedtime on the subsequent sleep episo...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12929

    authors: Cerasuolo M,Conte F,Cellini N,Fusco G,Giganti F,Malloggi S,Ficca G

    更新日期:2020-12-01 00:00:00

  • A systematic review and meta-analysis of wind turbine noise effects on sleep using validated objective and subjective sleep assessments.

    abstract::Little is known about the potential impacts of wind turbine noise (WTN) on sleep. Previous research is limited to cross-sectional studies reporting anecdotal impacts on sleep using inconsistent sleep metrics. This meta-analysis sought to comprehensively review studies evaluating the impact of WTN using widely accepted...

    journal_title:Journal of sleep research

    pub_type: 杂志文章,评审

    doi:10.1111/jsr.13228

    authors: Liebich T,Lack L,Hansen K,Zajamšek B,Lovato N,Catcheside P,Micic G

    更新日期:2020-11-12 00:00:00

  • Decreased body mass index during treatment with sodium oxybate in narcolepsy type 1.

    abstract::Narcolepsy type 1 is characterised by an increase in body weight after disease onset, frequently leading to obesity. It was suggested that this weight gain may be counteracted by treatment with sodium oxybate. We here provide longitudinal body mass index data of patients with narcolepsy type 1 after starting treatment...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12684

    authors: Schinkelshoek MS,Smolders IM,Donjacour CE,van der Meijden WP,van Zwet EW,Fronczek R,Lammers GJ

    更新日期:2019-06-01 00:00:00

  • Functional neuroimaging of normal human sleep by positron emission tomography.

    abstract::Functional neuroimaging using positron emission tomography has recently yielded original data on the functional neuroanatomy of human sleep. This paper attempts to describe the possibilities and limitations of the technique and clarify its usefulness in sleep research. A short overview of the methods of acquisition an...

    journal_title:Journal of sleep research

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2869.2000.00214.x

    authors: Maquet P

    更新日期:2000-09-01 00:00:00

  • Lucid dreaming: an age-dependent brain dissociation.

    abstract::The current study focused on the distribution of lucid dreams in school children and young adults. The survey was conducted on a large sample of students aged 6-19 years. Questions distinguished between past and current experience with lucid dreams. Results suggest that lucid dreaming is quite pronounced in young chil...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2012.01022.x

    authors: Voss U,Frenzel C,Koppehele-Gossel J,Hobson A

    更新日期:2012-12-01 00:00:00

  • Psychometric properties of the Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance and Sleep-Related Impairment item banks in adolescents.

    abstract::Sleep problems have a high prevalence and negative daytime consequences in adolescents. Current sleep measures for this age group have limitations. The Patient-Reported Outcomes Measurement Information System (PROMIS® ) developed sleep item banks for adults. In a previous validation study, these item banks were adapte...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.13029

    authors: van Kooten JAMC,Terwee CB,Luijten MAJ,Steur LMH,Pillen S,Wolters NGJ,Kaspers GJL,van Litsenburg RRL

    更新日期:2020-03-16 00:00:00

  • Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.

    abstract::Stimulants may provide short-term performance and alertness enhancement during sleep loss. Caffeine 600 mg, d-amphetamine 20 mg, and modafinil 400 mg were compared during 85 h of total sleep deprivation to determine the extent to which the three agents restored performance on simple psychomotor tasks, objective alertn...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2005.00468.x

    authors: Wesensten NJ,Killgore WD,Balkin TJ

    更新日期:2005-09-01 00:00:00

  • Procedural memory consolidation is associated with heart rate variability and sleep spindles.

    abstract::Sleep and memory studies often focus on overnight rather than long-term memory changes, traditionally associating overnight memory change (OMC) with sleep architecture and sleep patterns such as spindles. In addition, (para-)sympathetic innervation has been associated with OMC after a daytime nap using heart rate vari...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/jsr.12910

    authors: van Schalkwijk FJ,Hauser T,Hoedlmoser K,Ameen MS,Wilhelm FH,Sauter C,Klösch G,Moser D,Gruber G,Anderer P,Saletu B,Parapatics S,Zeitlhofer J,Schabus M

    更新日期:2020-06-01 00:00:00

  • Excessive daytime sleepiness in patients suffering from different levels of obstructive sleep apnoea syndrome.

    abstract::Excessive daytime sleepiness (EDS) is a frequent symptom of patients with obstructive sleep apnoea (OSA). EDS is a high-risk factor for accidents at work and on the road. Thirty untreated patients with different levels of severity of OSA were studied concerning night sleep and EDS. The criterion for severity was the r...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1046/j.1365-2869.2000.00211.x

    authors: Sauter C,Asenbaum S,Popovic R,Bauer H,Lamm C,Klösch G,Zeitlhofer J

    更新日期:2000-09-01 00:00:00

  • Post-CPAP sleepiness--a specific syndrome?

    abstract::Following treatment with continuous positive airway pressure (CPAP), some patients with obstructive sleep apnoea (OSA) remain sleepy despite effective CPAP and attention to other diagnoses that can provoke sleepiness. It is unclear if this residual sleepiness is an irreversible result of their previous OSA and merits ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1111/j.1365-2869.2007.00617.x

    authors: Stradling JR,Smith D,Crosby J

    更新日期:2007-12-01 00:00:00

  • The ability to self-monitor performance when fatigued.

    abstract::The present study aimed to systematically investigate the effects of elevated fatigue levels on the ability to self-monitor performance. Eighteen participants, aged 19-26 y, remained awake for a period of 28 h. Neurobehavioural performance was measured at hourly intervals using four tests from a standardized computer ...

    journal_title:Journal of sleep research

    pub_type: 杂志文章

    doi:10.1046/j.1365-2869.2000.00195.x

    authors: Dorrian J,Lamond N,Dawson D

    更新日期:2000-06-01 00:00:00