Abstract:
:Sixty ASA physical status I and II, premedicated patients were administered propofol 2 mg x kg-1 and remifentanil 2 microg x kg-1 (group R), alfentanil 50 microg x kg-1 (group A) or suxamethonium 1 mg x kg-1 (group S) as a rapid bolus. One minute after study drug administration, tracheal intubation was performed. Intubation conditions were then scored. Excellent or good conditions were observed in only 35% in group R compared with groups S and A (100% and 85%, respectively; p < 0.001). The haemodynamic response to tracheal intubation was blunted in groups R and A compared with group S (p < 0.001). The mean heart rate in groups R and A was significantly lower than group S (p < 0.001). We conclude that remifentanil 2 microg x kg-1 given as a rapid bolus will not produce intubating conditions as good as those obtained with alfentanil 50 microg x kg-1 or suxamethonium 1 mg x kg-1 if administered after propofol 2 mg x kg-1.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Alexander R,Booth J,Olufolabi AJ,El-Moalem HE,Glass PSdoi
10.1046/j.1365-2044.1999.01070.xsubject
Has Abstractpub_date
1999-11-01 00:00:00pages
1032-6issue
11eissn
0003-2409issn
1365-2044pii
ana1070journal_volume
54pub_type
临床试验,杂志文章,随机对照试验相关文献
ANAESTHESIA文献大全abstract::Alkalinisation of local anaesthetic drugs is a controversial technique for improving regional blockade. Forty-two patients scheduled for upper limb surgery received axillary brachial plexus anaesthesia using a cannula technique. Patients were randomly allocated to receive either lignocaine 1.5% with 1 in 200,000 adren...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1996.tb07712.x
更新日期:1996-02-01 00:00:00
abstract::A method of total intravenous anaesthesia for neurosurgery and neuroradiology is described using a continuous infusion of alphaxalone/alphadolone (Althesin) with analgesics and muscle relaxants. It has been used successfully on 272 occasions in 243 patients. The reasons for using such a technique and the advantages a...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1980.tb03823.x
更新日期:1980-05-01 00:00:00
abstract::We have prospectively assessed pain and anxiety of spinal puncture in 180 adult patients randomly allocated to one of three equal groups. On the morning of surgery group 1 had an EMLA patch, whereas group 2 and 3 had placebo patches. Group 2 also had infiltration analgesia with 2 ml lignocaine 2% with adrenaline, imme...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2044.1998.00608.x
更新日期:1998-12-01 00:00:00
abstract::The aim of this study was to compare conventional laryngeal mask airway sizing by weight with sizing by age in over- or underweight children. We studied 26 overweight (body mass index > 85th centile) and 26 underweight (body mass index < 15th centile) children. After general anaesthesia was induced, laryngeal mask air...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2009.06160.x
更新日期:2010-01-01 00:00:00
abstract::Sixty patients took part in a randomised, double-blind study to compare the analgesic and side effects of three opioid-containing solutions for patient-controlled epidural analgesia following abdominal surgery. Patients in group 1 received a solution containing bupivacaine 0.125% with fentanyl 10 micrograms.ml-1, grou...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1996.tb14993.x
更新日期:1996-11-01 00:00:00
abstract::The performance of the occlusion and Pethick tests in detecting faulty inner tubes in co-axial circle and Bain systems was compared. Twelve co-axial circle and 12 Bain anaesthetic breathing systems were tested using the occlusion and the Pethick tests. For each system, three tubes were intact, and the remaining nine h...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2008.05568.x
更新日期:2008-10-01 00:00:00
abstract::A case of pregnancy complicated by malignant hyperthermia susceptibility is reported. Serum CPK and electrolyte concentrations were measured during pregnancy and labour. Labour and delivery were managed successfully under epidural analgesia using plain bupivacaine 0.5%. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1979.tb04865.x
更新日期:1979-01-01 00:00:00
abstract::One hundred unpremedicated female patients of ASA grade 1 or 2 who underwent laparoscopy as outpatients were allocated randomly to one of four groups. All patients received general anaesthesia with fentanyl, thiopentone, halothane, nitrous oxide and oxygen; suxamethonium was given to facilitate tracheal intubation. In...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1990.tb14744.x
更新日期:1990-04-01 00:00:00
abstract::A case of aspiration pneumonia is reported after the use of a laryngeal mask airway in a young woman undergoing an elective cholecystectomy. The case illustrates the hazards of regurgitation with the laryngeal mask airway and the need for further evaluation when used with controlled mechanical ventilation. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1990.tb14882.x
更新日期:1990-12-01 00:00:00
abstract::Gastric emptying of orange-flavoured glucose (group I), low-fat milk (group II) and breast milk (group III) was evaluated in 45 ASA grade I children of < or = 5 years of age by using real-time ultrasonography and residual gastric volume and pH was then measured. In 15 more children, residual gastric volume and pH was ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2044.1999.00660.x
更新日期:1999-01-01 00:00:00
abstract::We assessed adequacy of ventilation in 20 critically ill patients with multiple organ failure using a Pneupac Ventipac portable ventilator and the effects on patients' haemodynamic stability. Baseline data were recorded over 15 min for a range of respiratory, haemodynamic and oxygen transport variables during ventilat...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1046/j.1365-2044.2001.02219.x
更新日期:2001-11-01 00:00:00
abstract::The absorption of morphine 10 mg after intramuscular injection into the gluteal and deltoid muscles was investigated. Ten patients received the injection into the deltoid and 10 were given the injection into the upper outer quadrant of the buttock. Blood was taken at frequent intervals up to 2 hours after the injectio...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1988.tb08976.x
更新日期:1988-04-01 00:00:00
abstract::Plasma phosphate concentration (Pi), red cell 2,3-diphosphoglycerate (2,3-DPG) and adenosine triphosphate (ATP) concentrations were measured pre-operatively and at intervals after operation for 30 h in twelve patients (nine males and three females, 44--61 years of age), who underwent open heart surgery. All patients r...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1978.tb08419.x
更新日期:1978-07-01 00:00:00
abstract::Maternal and cord levels of pancuronium were estimated using a fluorimetric method in a series of ten patients. Low concentrations of pancuronium (0-04--0-1 microng/ml) were found in all the cord samples analysed, indicating placental transfer of pancuronium. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1977.tb11628.x
更新日期:1977-04-01 00:00:00
abstract::A 5-year-old girl with Noonan's syndrome and a hypertrophic cardiomyopathy presented for myelography and subsequently, laminectomy. The anaesthetic management of the patient is described and the potential problems of the facial, cardiovascular and skeletal abnormalities associated with the condition are discussed. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1992.tb02010.x
更新日期:1992-02-01 00:00:00
abstract::The incidence and aetiology of peri-operative stroke in patients undergoing general surgical procedures are reviewed. Some general recommendations on the peri-operative anaesthetic management of these patients are summarised. ...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2044.1997.136-az0129.x
更新日期:1997-09-01 00:00:00
abstract::We have compared the performance of the Baxter disposable with the Graseby electronic patient-controlled analgesia system in 30 patients following major gynaecological surgery. Patients were allocated randomly to receive analgesia via the Baxter or Graseby device for postoperative pain relief. There were no significan...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1992.tb02020.x
更新日期:1992-02-01 00:00:00
abstract::Factors that influence the induction of anaesthesia with propofol were investigated in a prospective study of 1000 patients. Pre-operative albumin and urea concentrations correlated with the minimum induction dose of propofol, but less strong correlations were found with haemoglobin, globulin and total protein concent...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1991.tb09320.x
更新日期:1991-01-01 00:00:00
abstract::The 50% and 95% effective doses of desflurane for removal of the classic laryngeal mask airway after suction of the upper airway, in anaesthetised spontaneously breathing adult patients, are not known. To determine these, we studied 38 healthy patients, aged between 18 and 44 years. The target desflurane concentration...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2011.06620.x
更新日期:2011-04-01 00:00:00
abstract::Memory for stimuli presented during inhalation anaesthesia was tested in 80 children undergoing eye surgery. Two groups were exposed, in a random double-blind study, to repeated neutral phrases including either the colour orange or green. A postoperative colouring task was used as a test of implicit memory to detect a...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1992.tb03251.x
更新日期:1992-09-01 00:00:00
abstract::Various methods by which the Cape Minor ventilator may be used in the circle absorber system are described and the problems of the circuits described are considered. A new valve system is described which overcomes most of the problems encountered with other circuits. The economic advantages of an inexpensive ventilato...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1978.tb08327.x
更新日期:1978-11-01 00:00:00
abstract::We present a patient who suffered two episodes of torsade de pointes ventricular tachycardia during general anaesthesia for abdominal surgery. The first occurred on suctioning of the tracheobronchial tree and the second while anaesthesia was light. Since ST segment elevation was in each case noted before the onset of ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1996.tb12617.x
更新日期:1996-09-01 00:00:00
abstract::We investigated the effect of Buscopan 20 mg, given at the end of surgery, on analgesic requirements in 44 ASA I and II patients presenting as day cases for laparoscopic sterilisation using Filshie clips. Patients were randomly allocated to receive either intravenous Buscopan 20 mg or saline placebo at the end of surg...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2044.2001.01528-2.x
更新日期:2001-02-01 00:00:00
abstract::A case is described in which a woman with well controlled epilepsy and minor abnormalities of peripheral nerve function in the lower limbs experienced intense pain during the onset of a spinal anaesthetic for operation on burns on her thighs. Possible mechanisms and treatments are discussed. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1990.tb14335.x
更新日期:1990-06-01 00:00:00
abstract::We assessed the resistance to air flow in four commonly used air inlets. The Avon A81 and Codan air inlets provide the least resistance to flow, followed by the Baxter CO413 and lastly the Braun air inlet. The presence of a valve confers an advantage when rapid infusion of fluid is attempted. The valve in the Codan ai...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1994.tb14233.x
更新日期:1994-07-01 00:00:00
abstract::Sixty-seven patients undergoing general anaesthesia for exodontia as outpatients were studied in order to measure the levels of oxygen saturation. Both the anaesthesia and extractions were performed by fourth year dental undergraduates working under direct supervision. Falls in oxygen saturation in excess of 5% were f...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1984.tb08937.x
更新日期:1984-11-01 00:00:00
abstract::Fazadinium was administered as an intravenous bolus of 0.5 or 1 mg/kg to nine patients during neurolept-anaesthesia. Continuous recording of neuromuscular activity and serial collection of blood samples for drug assay allowed the relationship between neuromuscular blockade and plasma fazadinium concentration to be stu...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1980.tb03946.x
更新日期:1980-09-01 00:00:00
abstract::Continuous epidural analgesia may be complicated by intravascular or subarachnoid injection of local analgesic, with disastrous consequences. One of the techniques described to prevent these complications is the aspiration test. It is the current standard of practice to employ a micropore bacterial filter for epidural...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1991.tb09660.x
更新日期:1991-07-01 00:00:00
abstract::Coagulopathy in patients with traumatic brain injury is associated with an increase in morbidity and mortality. Although timely and aggressive treatment of coagulopathy is of paramount importance, excessive transfusion of blood products has been linked with poor long-term outcomes in patients with traumatic brain inju...
journal_title:Anaesthesia
pub_type: 杂志文章,多中心研究
doi:10.1111/anae.14670
更新日期:2019-07-01 00:00:00
abstract::A prospective, randomised, double-blind study was conducted to compare the efficacy of two doses of levobupivacaine combined with sufentanil for continuous epidural infusion following thoractomy. A total of 72 patients undergoing lobectomy or pneumonectomy were enrolled. An epidural catheter was inserted between the l...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2007.05184.x
更新日期:2007-10-01 00:00:00