Factors that influence the induction dose of propofol.

Abstract:

:Factors that influence the induction of anaesthesia with propofol were investigated in a prospective study of 1000 patients. Pre-operative albumin and urea concentrations correlated with the minimum induction dose of propofol, but less strong correlations were found with haemoglobin, globulin and total protein concentrations. Age was an important influence on the induction dose of propofol (r = -0.34) which was also closely related to ASA grade. Induction of anaesthesia with propofol is dependent on a number of variables, and this study suggests that pre-operative albumin and urea concentrations are important.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

McCleane GJ,Fogarty DF,Watters CH

doi

10.1111/j.1365-2044.1991.tb09320.x

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

59-61

issue

1

eissn

0003-2409

issn

1365-2044

journal_volume

46

pub_type

杂志文章
  • Hypotension, subarachnoid block and the elderly patient.

    abstract::This article reviews the current literature on the management of hypotension during subarachnoid block in the elderly. Hypotension results from blockade of the sympathetic nervous system, which causes decreases in both systemic vascular resistance and cardiac output. Abolition of normal cardiovascular reflexes is also...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.1996.tb15051.x

    authors: Critchley LA

    更新日期:1996-12-01 00:00:00

  • Hypophosphataemia and its consequences in patients following open heart surgery.

    abstract::Plasma phosphate concentration (Pi), red cell 2,3-diphosphoglycerate (2,3-DPG) and adenosine triphosphate (ATP) concentrations were measured pre-operatively and at intervals after operation for 30 h in twelve patients (nine males and three females, 44--61 years of age), who underwent open heart surgery. All patients r...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1978.tb08419.x

    authors: Swaminathan R,Morgan DB,Ionescu M,Hill GL

    更新日期:1978-07-01 00:00:00

  • Evaluation of echocardiography indices of systolic function: a comparative study using pressure-volume loops in patients undergoing coronary artery bypass surgery.

    abstract::Transoesophageal echocardiography measures of systolic left ventricular function obtained during coronary artery bypass surgery are heavily influenced by alterations in loading conditions. No validation of these measurements against load independent indices obtained by pressure-volume loop analysis has been undertaken...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2006.04911.x

    authors: Royse CF,Connelly KA,MacLaren G,Royse AG

    更新日期:2007-02-01 00:00:00

  • Peri-operative stroke in general surgical patients.

    abstract::The incidence and aetiology of peri-operative stroke in patients undergoing general surgical procedures are reviewed. Some general recommendations on the peri-operative anaesthetic management of these patients are summarised. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.1997.136-az0129.x

    authors: Kam PC,Calcroft RM

    更新日期:1997-09-01 00:00:00

  • Patient-controlled analgesia: a double-blind study in burn patients.

    abstract::A double-blind controlled study was performed to assess the efficacy and safety of patient-controlled analgesia in burn patients. This method was compared with conventional analgesic therapy consisting of intermittent intravenous morphine injections. Twenty-four adult patients hospitalised for burn injuries participat...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1992.tb02266.x

    authors: Choiniere M,Grenier R,Paquette C

    更新日期:1992-06-01 00:00:00

  • Persistent abdominal pain. Treatment by lumbar sympathetic lysis.

    abstract::The organic and psychological problems of patients suffering from chronic abdominal pain are described and three case histories of patients who had undergone multiple surgery for their abdominal pain are presented. All three were treated by lumbar sympathetic lysis, resulting in relief of their pain. The possible reas...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1981.tb10202.x

    authors: Duthie AM,Ingham V

    更新日期:1981-03-01 00:00:00

  • Dose-response relationship for disoprofol (ICI 35868; Diprivan). Comparison with methohexitone.

    abstract::The duration of sleep following intravenous administration of three doses of disoprofol (1.2 and 3 mg/kg) was compared with that following methohexione 1 or 2 mg/kg. Disoprofol and methohexitone were shown to be approximately equipotent. Side-effects were dose-related for both drugs, but the incidence was significantl...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1981.tb08858.x

    authors: Kay B,Stephenson DK

    更新日期:1981-09-01 00:00:00

  • A dedicated intravenous cannula for postoperative use effect on incidence and severity of phlebitis.

    abstract::A prospective, randomised, controlled clinical study was performed to compare the incidence and severity of postoperative peripheral venous thrombophlebitis associated with a single intravenous cannula used for both intra-operative and postoperative purposes, and two cannulae, one used intra-operatively and the other ...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.2002.02786.x

    authors: Panadero A,Iohom G,Taj J,Mackay N,Shorten G

    更新日期:2002-09-01 00:00:00

  • A combined high frequency oscillator and intermittent positive pressure ventilator.

    abstract::A high frequency oscillator and its interface with the Siemens 900C ventilator form a combined high frequency oscillator and intermittent positive pressure ventilator. This combined high frequency ventilator is designed for use in selected cases of refractory hypoxaemia. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1995.tb15114.x

    authors: Raphael JH,Atkinson I,Bexton MD

    更新日期:1995-07-01 00:00:00

  • Blood disoprofol levels in anesthetised patients. Correlation of concentrations after single or repeated doses with hypnotic activity.

    abstract::The blood concentrations of disoprofol (Diprivan) after single intravenous doses of 1, 2 or 3 mg/kg have been examined in a subpopulation from previously reported clinical studies. The linear relationship between sleep time and dose could be explained by the linearity of the pharmacokinetics at these doses. After a si...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1982.tb01223.x

    authors: Adam HK,Kay B,Douglas EJ

    更新日期:1982-05-01 00:00:00

  • The effect of the European Working Time Directive on anaesthetic working patterns and training.

    abstract::There is concern that the European Working Time Directive 2009 has led to reduced time available for training, and this study examined if this has been the case. For two identical six-month periods in 1999 (pre-Directive) and 2009 (post-Directive), weekly data were collected on the total number of sessions attended by...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2012.07227.x

    authors: Paul RG,Bunker N,Fauvel NJ,Cox M

    更新日期:2012-09-01 00:00:00

  • Misplacement of multihole epidural catheters--a report of two cases.

    abstract::The misplacement of a multihole (three lateral holes) epidural catheter such that it lies partly in the subdural space is demonstrated in two patients by means of epidurographic studies. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1996.tb07753.x

    authors: Sala-Blanch X,Martinez-Palli G,Agusti-Lasus M,Nalda-Felipe MA

    更新日期:1996-04-01 00:00:00

  • Rates of lumbosacral transforaminal injections interpreted as intravascular: fluoroscopy alone or with digital subtraction.

    abstract::We investigated the rate of injections interpreted as intravascular during imaging of lumbosacral transforaminal epidural injections, using fluoroscopy alone or with digital subtraction. We evaluated 732 injections performed on 348 patients: 8.1% (59/732) and 10.5% (77/732) of injections were interpreted as intravascu...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.12362

    authors: Kim YH,Park HJ,Moon DE

    更新日期:2013-11-01 00:00:00

  • A new method of predicting pulmonary capillary wedge pressure: the arterial pressure ratio.

    abstract::The response of arterial blood pressure to an increase in intrathoracic pressure has been shown to be predictive of pulmonary capillary wedge pressure. We devised a new method, which we termed the arterial pressure ratio. We defined arterial pressure ratio as the ratio of systolic blood pressure of the final beat duri...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2000.055002113.x

    authors: Uehara H,Takenaka I,Aoyama K,Kadoya T,Sata T,Shigematsu A

    更新日期:2000-02-01 00:00:00

  • The impact of respiratory protective equipment on difficult airway management: a randomised, crossover, simulation study.

    abstract::The current international COVID-19 health crisis underlines the importance of adequate and suitable personal protective equipment for clinical staff during acute airway management. This study compares the impacts of standard air-purifying respirators and powered air-purifying respirators during simulated difficult air...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/anae.15102

    authors: Schumacher J,Arlidge J,Dudley D,Sicinski M,Ahmad I

    更新日期:2020-10-01 00:00:00

  • The use of a blood conservation pressure transducer system in critically ill patients.

    abstract::We tried to determine if a blood conservation pressure transducer system reduced blood transfusions, increased haemoglobin concentration or reduced line infections in critically ill patients. One hundred patients were randomly allocated to conventional or blood conserving systems attached to systemic and pulmonary art...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.2000.01129.x

    authors: Thorpe S,Thomas AN

    更新日期:2000-01-01 00:00:00

  • Dutch case-control study of anaesthesia-related morbidity and mortality. Rationale and methods.

    abstract::To date, anaesthesia-related mortality, morbidity and risk factors have almost exclusively been studied qualitatively rather than quantitatively. Therefore, knowledge of the relative risk associated with many anaesthesia-related factors is still lacking. Recently, a quantitative study of the determinants and preventio...

    journal_title:Anaesthesia

    pub_type: 杂志文章,多中心研究

    doi:10.1046/j.1365-2044.1998.00303.x

    authors: Arbous MS,Grobbee DE,van Kleef JW,Meursing AE

    更新日期:1998-02-01 00:00:00

  • The legal responsibility of the anaesthetist.

    abstract::The various ways in which an anaesthetist may come into contact with the process of the criminal and civil law have been discussed. Some comparisons have been made between the English Law and that of other countries. The need for vigilance by professional bodies representing medical practitioners in monitoring and mak...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1977.tb11553.x

    authors: Havard JD

    更新日期:1977-01-01 00:00:00

  • A comparison of different modes of noninvasive ventilatory support: effects on ventilation and inspiratory muscle effort.

    abstract::The aims of noninvasive ventilation include the correction of hypoventilation and unloading of inspiratory muscles. Volume cycled flow generators, bi-level positive airway pressure and continuous positive airway pressure techniques have all been used with face and nasal masks. We have compared these modes of ventilato...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1994.tb14173.x

    authors: Elliott MW,Aquilina R,Green M,Moxham J,Simonds AK

    更新日期:1994-04-01 00:00:00

  • Perineuronal morphine: a comparison with epidural morphine.

    abstract::In a double-blind, randomised controlled cross-over study the effects of perineuronal (perifemoral) injections of morphine were compared with epidural injections with the same amount of morphine in patients after knee surgery. Better pain scores were achieved during treatment with epidural morphine. We have not been a...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1988.tb06632.x

    authors: Dahl JB,Daugaard JJ,Kristoffersen E,Johannsen HV,Dahl JA

    更新日期:1988-06-01 00:00:00

  • A randomised trial comparing the laryngeal mask airway Supreme™ with the laryngeal mask airway Unique™ in children.

    abstract::We conducted a randomised controlled trial comparing the laryngeal mask airway Supreme(™) with the laryngeal mask airway Unique(™) in children. Fifty children presenting for elective surgery were randomly assigned to receive either the laryngeal mask airway Supreme or laryngeal mask airway Unique. The outcomes measure...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2011.06960.x

    authors: Jagannathan N,Sohn LE,Sawardekar A,Chang E,Langen KE,Anderson K

    更新日期:2012-02-01 00:00:00

  • The effect of pre-emptive acupuncture treatment on analgesic requirements after day-case knee arthroscopy.

    abstract::The role of acupuncture analgesia in the management of postoperative pain is yet to be clearly evaluated. We conducted a prospective, double-blind, randomised controlled study to evaluate the effect of acupuncture pretreatment on the analgesic requirement after knee arthroscopy. Forty-two patients presenting for unila...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.1999.01030.x

    authors: Gupta S,Francis JD,Tillu AB,Sattirajah AI,Sizer J

    更新日期:1999-12-01 00:00:00

  • Anaesthetic staffing in England and Wales.

    abstract::The numbers of anaesthetists and of surgeons in the English Health Regions and in Wales as at September 1978, are given in whole-time equivalents per 100,000 of population. All Regional figures are presented as percentages of the national average so that comparisons between Regions can be made. Marked inter-Regional d...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1980.tb05045.x

    authors: Rees LT

    更新日期:1980-11-01 00:00:00

  • Peribulbar anaesthesia using a mixture of local anaesthetic and vecuronium.

    abstract::The aim of this double-blind, randomised study was to assess the effects of the addition of 0.5 mg of vecuronium bromide to a standard local anaesthetic mixture used for peribulbar anaesthesia. We studied 60 patients undergoing regional anaesthesia for intra-ocular surgery and were primarily interested in the quality ...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.1998.00433.x

    authors: Reah G,Bodenham AR,Braithwaite P,Esmond J,Menage MJ

    更新日期:1998-06-01 00:00:00

  • Clinical pharmacokinetics of fazadinium.

    abstract::Fazadinium was administered as an intravenous bolus of 0.5 or 1 mg/kg to nine patients during neurolept-anaesthesia. Continuous recording of neuromuscular activity and serial collection of blood samples for drug assay allowed the relationship between neuromuscular blockade and plasma fazadinium concentration to be stu...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1980.tb03946.x

    authors: Bevan DR,D'Souza J,Rouse JM,Caldwell J,Smith RL

    更新日期:1980-09-01 00:00:00

  • In vivo animal studies with sugammadex.

    abstract::A review is presented of animal studies of the selective steroidal neuromuscular blocking drug binding agent sugammadex. These studies demonstrate that sugammadex is faster in onset than the currently used acetylcholinesterase inhibitors, has no muscarinic effects, and is characterised by lack of adverse effects on ot...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.2008.05869.x

    authors: Booij LH,van Egmond J,Driessen JJ,de Boer HD

    更新日期:2009-03-01 00:00:00

  • Hypercholinesterasaemia and suxamethonium resistance.

    abstract::A case is reported of resistance to the muscle relaxing action of suxamethonium due to the rare inherited condition of hypercholinesterasaemia. Family studies suggest dominant inheritance. It is suggested the condition should be considered whenever there is unexpected resistance to the muscle relaxing action of suxame...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1987.tb04110.x

    authors: Warran P,Theeman M,Bold AM,Jones S

    更新日期:1987-08-01 00:00:00

  • Effect of cricoid pressure on the incidence of nausea and vomiting in the immediate postoperative period.

    abstract::This study aimed to evaluate whether the application of cricoid pressure at the time of induction of anaesthesia was associated with a lesser incidence of postoperative nausea or vomiting in the immediate postoperative period compared with a group in which no cricoid pressure was applied, in patients undergoing day ca...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.2000.055002163.x

    authors: Khan FA,ul Haq A

    更新日期:2000-02-01 00:00:00

  • Pre-oxygenation and apnoea in pregnancy: changes during labour and with obstetric morbidity in a computational simulation.

    abstract::Using the Nottingham Physiology Simulator, we investigated the effects on pre-oxygenation and apnoea during rapid sequence induction of labour, obesity, sepsis, pre-eclampsia, maternal haemorrhage and multiple pregnancy in term pregnancy. Pre-oxygenation with 100% oxygen was followed by simulated rapid sequence induct...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2008.05785.x

    authors: McClelland SH,Bogod DG,Hardman JG

    更新日期:2009-04-01 00:00:00

  • An anti-pollution modification for the Cape-Waine anaesthetic ventilator.

    abstract::Most anaesthetic equipment needs to be modified to fulfil anti-pollution recommendations. A method of modifying a Cape-Waine Anaesthetic Ventilator is described in detail showing what parts need to be replaced or removed. A list of the new parts required together with their cost is given and the modification can be ma...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1977.tb09968.x

    authors: Zorab JS,Fox DE

    更新日期:1977-11-01 00:00:00