A comparison of opioid solutions for patient-controlled epidural analgesia.

Abstract:

:Sixty patients took part in a randomised, double-blind study to compare the analgesic and side effects of three opioid-containing solutions for patient-controlled epidural analgesia following abdominal surgery. Patients in group 1 received a solution containing bupivacaine 0.125% with fentanyl 10 micrograms.ml-1, group 2 bupivacaine 0.125% with diamorphine 125 micrograms.ml-1, group 3 pethidine 2.5 mg.ml-1. All groups received 4 ml.h-1 background infusion and 3 ml boluses every 20 min if necessary. There were no significant differences between the groups in visual analogue scale pain scores (p = 0.537) or volumes of solution used at 24 h (p = 0.351) or 48 h (p = 0.105). Motor block was significantly higher in group 2 (p < 0.004) and pruritus occurred significantly less in group 3 (p < 0.05). We conclude that these three solutions produce equivalent analgesia but that pethidine 2.5 mg.ml-1 may be associated with fewer side effects.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Smith AJ,Haynes TK,Roberts DE,Harmer M

doi

10.1111/j.1365-2044.1996.tb14993.x

subject

Has Abstract

pub_date

1996-11-01 00:00:00

pages

1013-7

issue

11

eissn

0003-2409

issn

1365-2044

journal_volume

51

pub_type

临床试验,杂志文章,随机对照试验
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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1996.tb12607.x

    authors: Lilley EM,Isert PR,Carasso ML,Kennedy RA

    更新日期:1996-09-01 00:00:00

  • Incidence of and risk factors for difficult ventilation via a supraglottic airway device in a population of 14,480 patients from South-East Asia.

    abstract::Difficult airway practice guidelines include the use of a supraglottic airway device as part of the armamentarium to provide and maintain ventilation and oxygenation. We retrospectively reviewed 14 480 patients aged ≥ 18 years who underwent general anaesthesia. We identified 74 (0.5%) patients whose lungs were identif...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.13153

    authors: Saito T,Liu W,Chew ST,Ti LK

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  • The addition of dexamethasone to dolasetron or haloperidol for treatment of established postoperative nausea and vomiting.

    abstract::It is not known whether dexamethasone increases the effectiveness of anti-emetics when given to treat postoperative nausea and vomiting (PONV). In a randomised study, 242 patients who were experiencing PONV received dolasetron and placebo, haloperidol and placebo, dolasetron and dexamethasone, or haloperidol and dexam...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2007.05136.x

    authors: Rüsch D,Arndt C,Martin H,Kranke P

    更新日期:2007-08-01 00:00:00

  • Vecuronium and atracurium infusions during hypothermic cardiopulmonary bypass.

    abstract::Two similar groups of patients undergoing coronary artery bypass grafting received either atracurium or vecuronium infusions for neuromuscular blockade. Both groups demonstrated a marked reduction in neuromuscular blocking requirements during hypothermic bypass at 30 C. The ratio of the dose rates at 30 C to that at 3...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1986.tb12916.x

    authors: Denny NM,Kneeshaw JD

    更新日期:1986-09-01 00:00:00

  • The value of risks scores for predicting postoperative nausea and vomiting when used to compare patient group in a randomised controlled trial.

    abstract::Whilst conducting a randomised controlled trial into the effects of combination anti-emetics, we endeavoured to confirm that our patient groups were matched using the predictive scoring systems for postoperative nausea and vomiting (PONV) and postoperative vomiting (POV) reported in the literature. One hundred and sev...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2002.02782_4.x

    authors: Thomas R,Jones NA,Strike P

    更新日期:2002-11-01 00:00:00

  • Pneumothorax in the neonatal period.

    abstract::The incidence of pneumothorax in the neonatal period is reviewed. Most infants who developed a pneumothorax were undergoing intermittent positive pressure ventilation. The most common underlying pathology associated with pneumothorax was idiopathic respiratory distress syndrome. This was the only condition in which a ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1983.tb12024.x

    authors: Jones RM,Rutter N,Cooper AC,Pullan CR

    更新日期:1983-10-01 00:00:00

  • Cardiovascular effects of epidural local anaesthetics. Comparison of 0.75% bupivacaine and 0.75% ropivacaine, both with adrenaline.

    abstract::The cardiovascular effects of 20 ml 0.75% bupivacaine with adrenaline 5 micrograms/ml injected epidurally were compared with those of 20 ml 0.75% ropivacaine with adrenaline. Cardiovascular measurements were performed with a transthoracic electrical bioimpedance monitor. The maximum mean arterial blood pressure decrea...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1991.tb09544.x

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    更新日期:1991-05-01 00:00:00

  • An intra-operative comparison of lumbar with thoracic epidural sufentanil for thoracotomy.

    abstract::The efficacy of thoracic epidural sufentanil 50 micrograms was compared with lumbar epidural sufentanil 50 micrograms in 30 patients (n = 15 in each group) undergoing lateral thoracotomy. Sufentanil was administered epidurally after induction of anaesthesia with sufentanil 1 microgram.kg-1 and thiopentone 2-5 mg.kg-1 ...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1994.tb03366.x

    authors: Haak-van der Lely F,van Kleef JW,Burm AG,Bovill JG

    更新日期:1994-02-01 00:00:00

  • The effect of subhypnotic doses of propofol on the incidence of pruritus after intrathecal morphine for caesarean section.

    abstract::The effect of subhypnotic doses of propofol on intrathecal morphine-induced pruritus was studied in a prospective, randomly allocated, double-blind controlled trial. Fifty-eight women undergoing elective lower segment Caesarean section for a singleton fetus received spinal anaesthesia with 2.5 ml hyperbaric 0.5% bupiv...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1997.069-az0060.x

    authors: Warwick JP,Kearns CF,Scott WE

    更新日期:1997-03-01 00:00:00

  • The effect of a heat and moisture exchanger on gas flow in a Mapleson F breathing system during inhalational induction.

    abstract::Heat and moisture exchangers (HMEs) humidify, warm and filter inspired gas, protecting patients and apparatus during anaesthesia. Their incorporation into paediatric anaesthetic breathing systems is recommended. We experienced delays in inhalational induction whilst using a Mapleson F breathing system with an HME. We ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2000.01521.x

    authors: Da Fonseca JM,Wheeler DW,Pook JA

    更新日期:2000-06-01 00:00:00

  • Comparison of the Williams Airway Intubator and Ovassapian Fibreoptic Intubating Airway for fibreoptic orotracheal intubation.

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    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2004.03527.x

    authors: Greenland KB,Lam MC,Irwin MG

    更新日期:2004-02-01 00:00:00

  • Pulmonary shunts in the prone position.

    abstract::Pulmonary shunting (Qs/Qt with the FIO2 = 1) was determined in ten young healthy non-obese patients prior to anaesthesia, 30 min after induction in the supine position and 1 h later during surgery in the prone position. Respiration was spontaneous in awake patients and was controlled following the induction of anaesth...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1978.tb08387.x

    authors: Stone JG,Khambatta HJ

    更新日期:1978-06-01 00:00:00

  • Damage to the laryngeal mask by residual fluid in the cuff.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1997.242-az0377.x

    authors: Asai T,Koga K,Morris S

    更新日期:1997-10-01 00:00:00

  • Impact of a physician-led pre-hospital critical care team on outcomes after major trauma.

    abstract::The deployment of physician-led pre-hospital enhanced care teams capable of critical care interventions at the scene of injury may confer a survival benefit to victims of major trauma. However, the evidence base for this widely adopted model is disputed. Failure to identify a clear survival benefit has been attributed...

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    pub_type: 杂志文章

    doi:10.1111/anae.14501

    authors: Hepple DJ,Durrand JW,Bouamra O,Godfrey P

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  • Apnoeic oxygenation in paediatric anaesthesia: a narrative review.

    abstract::Apnoeic oxygenation refers to oxygenation in the absence of any patient or ventilator effort to move the lungs. This phenomenon was first described in humans in the mid-20th century but has seen renewed interest in the last decade following the demonstration of apnoeic oxygenation with low-flow, and subsequently high-...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/anae.15107

    authors: Lyons C,Callaghan M

    更新日期:2021-01-01 00:00:00

  • A new, minimally invasive technique for measuring cardiac index: clinical comparison of continuous cardiac dynamic monitoring and pulmonary artery catheter methods.

    abstract::To assess the utility of a relatively simple bedside method of estimating cardiac index during major surgery or in the intensive care unit, we conducted a prospective study in patients undergoing elective cardiac bypass surgery where a pulmonary artery catheter was inserted as part of routine monitoring. The cardiac i...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2009.05943.x

    authors: Berridge JC,Warring-Davies K,Bland JM,Quinn AC

    更新日期:2009-09-01 00:00:00

  • Diagnostic accuracy of anaesthesiologists' prediction of difficult airway management in daily clinical practice: a cohort study of 188 064 patients registered in the Danish Anaesthesia Database.

    abstract::Both the American Society of Anesthesiologists and the UK NAP4 project recommend that an unspecified pre-operative airway assessment be made. However, the choice of assessment is ultimately at the discretion of the individual anaesthesiologist. We retrieved a cohort of 188 064 cases from the Danish Anaesthesia Databas...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.12955

    authors: Nørskov AK,Rosenstock CV,Wetterslev J,Astrup G,Afshari A,Lundstrøm LH

    更新日期:2015-03-01 00:00:00

  • The emergency management of diabetes mellitus.

    abstract::Some of the acute metabolic derangements of unstable diabetes have been discussed. The management of patients undergoing surgical operations has also been considered. No problems are usually encountered in diabetic patients treated with diet alone or with oral hypoglycaemic compounds, although chlorpropamide may need ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1975.tb00900.x

    authors: Maw DS

    更新日期:1975-07-01 00:00:00

  • Hypophosphataemia and its consequences in patients following open heart surgery.

    abstract::Plasma phosphate concentration (Pi), red cell 2,3-diphosphoglycerate (2,3-DPG) and adenosine triphosphate (ATP) concentrations were measured pre-operatively and at intervals after operation for 30 h in twelve patients (nine males and three females, 44--61 years of age), who underwent open heart surgery. All patients r...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1978.tb08419.x

    authors: Swaminathan R,Morgan DB,Ionescu M,Hill GL

    更新日期:1978-07-01 00:00:00

  • An objective assessment of nerve stimulators used for peripheral nerve blockade*.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2006.04645.x

    authors: Jochum D,Iohom G,Diarra DP,Loughnane F,Dupré LJ,Bouaziz H

    更新日期:2006-06-01 00:00:00

  • Transtracheal illumination for optimal tracheal tube placement. A clinical study.

    abstract::The tracheas of 420 adult patients were intubated using the tip of a lighted stylet placed inside the lumen of the tracheal tube, just proximal to the tube cuff. The maximum point of transillumination was visible just distal to the cricoid cartilage, with proper cuff positioning. The lighted stylet was also introduced...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1989.tb09198.x

    authors: Mehta S

    更新日期:1989-12-01 00:00:00

  • A comparison of different modes of noninvasive ventilatory support: effects on ventilation and inspiratory muscle effort.

    abstract::The aims of noninvasive ventilation include the correction of hypoventilation and unloading of inspiratory muscles. Volume cycled flow generators, bi-level positive airway pressure and continuous positive airway pressure techniques have all been used with face and nasal masks. We have compared these modes of ventilato...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1994.tb14173.x

    authors: Elliott MW,Aquilina R,Green M,Moxham J,Simonds AK

    更新日期:1994-04-01 00:00:00

  • Extracorporeal carbon dioxide removal using the Novalung in a patient with intracranial bleeding.

    abstract::A neurosurgical patient who required repeated surgery for intracranial haematoma developed acute respiratory distress syndrome. Raised intracranial pressure proved difficult to manage whilst attempting to maintain optimal gas exchange. The resultant arterial partial pressure of carbon dioxide remained unacceptably hig...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2006.04863.x

    authors: Mallick A,Elliot S,McKinlay J,Bodenham A

    更新日期:2007-01-01 00:00:00

  • Epidural anaesthesia and thrombocytopenia.

    abstract::A case is presented of a mother with unanticipated profound thrombocytopenia who received a continuous epidural anaesthetic for labour. No neurological sequelae or excessive bleeding occurred. It is clear, after a review of the literature, that more information is needed to define the lower limits of platelet count at...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1989.tb09270.x

    authors: Hew-Wing P,Rolbin SH,Hew E,Amato D

    更新日期:1989-09-01 00:00:00

  • Prediction of prolonged laryngoscopy.

    abstract::Duration of laryngoscopy must be kept as short as possible to prevent disturbances of oxygenation and ventilation. Because the factors associated with prolonged laryngoscopy are not well known, we studied 1000 patients undergoing tracheal intubation under general anaesthesia to determine the possible effects of their ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2001.02084-5.x

    authors: Saghaei M,Safavi MR

    更新日期:2001-12-01 00:00:00

  • The effect of midazolam premedication on implicit memory activation during alfentanil-nitrous oxide anaesthesia.

    abstract::Eighty-three patients were given midazolam 0.1 mg.kg-1 by intramuscular injection as premedication before general anaesthesia with alfentanil-nitrous oxide. During anaesthesia patients were presented (through headphones) with either statements about common facts of some years ago (group A) (n = 43) or new verbal assoc...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1995.tb04553.x

    authors: De Roode A,Jelicic M,Bonke B,Bovill JG

    更新日期:1995-03-01 00:00:00

  • An anti-pollution modification for the Cape-Waine anaesthetic ventilator.

    abstract::Most anaesthetic equipment needs to be modified to fulfil anti-pollution recommendations. A method of modifying a Cape-Waine Anaesthetic Ventilator is described in detail showing what parts need to be replaced or removed. A list of the new parts required together with their cost is given and the modification can be ma...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1977.tb09968.x

    authors: Zorab JS,Fox DE

    更新日期:1977-11-01 00:00:00

  • Severe hypotension due to intramyometrial injection of prostaglandin E2.

    abstract::Treatment of postpartum haemorrhage because of uterine atony with intramyometrial prostaglandin E2 1 mg, in an anaesthetised patient resulted in life-threatening hypotension. Anaesthetists should be aware of the potential cardiovascular side effects of prostaglandins. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1990.tb14569.x

    authors: Kilpatrick AW,Thorburn J

    更新日期:1990-10-01 00:00:00

  • Evidence for benefit vs novelty in new intubation equipment.

    abstract::A myriad of new intubation equipment has been introduced commercially since the appearance of Macintosh/Miller blades in the 1940s. We review the role of devices that are relevant to current clinical practice based on their presence in the scientific literature. The comparative performance of new vs traditional direct...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.2011.06935.x

    authors: Behringer EC,Kristensen MS

    更新日期:2011-12-01 00:00:00

  • Effect of orientation of a standard polyvinyl chloride tracheal tube on success rates during awake flexible fibreoptic intubation.

    abstract::We conducted a randomised study in 70 patients to assess the effect of orientation of a standard polyvinyl chloride tracheal tube on the ease of railroading the tube during awake fiberoptic orotracheal intubation. Conventional orientation of the tube (with the bevel of the tube directed to the patient's left) was comp...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2006.04750.x

    authors: Sharma D,Bithal PK,Rath GP,Pandia MP

    更新日期:2006-09-01 00:00:00