Abstract:
:It is not known whether dexamethasone increases the effectiveness of anti-emetics when given to treat postoperative nausea and vomiting (PONV). In a randomised study, 242 patients who were experiencing PONV received dolasetron and placebo, haloperidol and placebo, dolasetron and dexamethasone, or haloperidol and dexamethasone. The results from 228 patients were suitable for analysis. PONV recurred significantly less frequently in patients treated with additional dexamethasone (33%) than in patients treated without additional dexamethasone (51%). The combination of dexamethasone with dolasetron or dexamethasone with haloperidol is superior to dolasetron or haloperidol alone for the treatment of PONV.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Rüsch D,Arndt C,Martin H,Kranke Pdoi
10.1111/j.1365-2044.2007.05136.xsubject
Has Abstractpub_date
2007-08-01 00:00:00pages
810-7issue
8eissn
0003-2409issn
1365-2044pii
ANA5136journal_volume
62pub_type
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