Abstract:
:Despite the ongoing coronavirus disease 2019 (COVID-19) pandemic, elective paediatric surgery must continue safely through the first, second and subsequent waves of disease. This study presents outcome data from a children's hospital in north-west England, the region with the highest prevalence of COVID-19 in England. Children and young people undergoing elective surgery isolated within their household for 14 days, then presented for real-time reverse transcriptase polymerase chain reaction testing for severe acute respiratory syndrome coronavirus disease-2 (SARS-CoV-2) within 72 h of their procedure (or rapid testing within 24 h in high-risk cases), and completed a screening questionnaire on admission. Planned surgery resumed on 26 May 2020; in the four subsequent weeks, there were 197 patients for emergency and 501 for elective procedures. A total of 488 out of 501 (97.4%) elective admissions proceeded, representing a 2.6% COVID-19-related cancellation rate. There was no difference in the incidence of SARS-CoV-2 among children and young people who had or had not isolated for 14 days (p > 0.99). One out of 685 (0.1%) children who had surgery re-presented to the hospital with symptoms potentially consistent with SARS-CoV-2 within 14 days of surgery. Outcomes were similar to those in the same time period in 2019 for length of stay (p = 1.0); unplanned critical care admissions (p = 0.59); and 14-day hospital re-admission (p = 0.17). However, the current cohort were younger (p = 0.037); of increased complexity (p < 0.001) and underwent more complex surgery (p < 0.001). The combined use of household self-isolation, testing and screening questionnaires has allowed the re-initiation of elective paediatric surgery at high volume while maintaining pre-COVID-19 outcomes in children and young people undergoing surgery. This may provide a model for addressing the ongoing challenges posed by COVID-19, as well as future pandemics.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Okonkwo INC,Howie A,Parry C,Shelton CL,Cobley S,Craig R,Permall N,El-Sheikha SH,Herbert N,Arnold Pdoi
10.1111/anae.15264subject
Has Abstractpub_date
2020-12-01 00:00:00pages
1605-1613issue
12eissn
0003-2409issn
1365-2044journal_volume
75pub_type
杂志文章相关文献
ANAESTHESIA文献大全abstract::The demyelinating diseases are classified and the current concepts of the aetiology and pathophysiology of the most common of these diseases, multiple sclerosis, are described. The effects of the impaired function, local responses and known complications of the disease on the choice of anaesthetic, drugs and technique...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2044.1980.tb03947.x
更新日期:1980-09-01 00:00:00
abstract::Modern four-factor prothrombin complex concentrate was designed originally for rapid targeted replacement of the coagulation factors II, VII, IX and X. Dosing strategies for the approved indication of vitamin K antagonist-related bleeding vary greatly. They include INR and bodyweight-related protocols as well as fixed...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.15181
更新日期:2020-07-17 00:00:00
abstract::A case is described in which recovery from the administration of a single dose of etomidate was complicated by periodic episodes of unconsciousness, tremor and apnoea. Subsequent investigations did not reveal any evidence of neurological disease. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1988.tb05415.x
更新日期:1988-01-01 00:00:00
abstract::To date, the dosing of sugammadex is based on real body weight without taking fat content into account. We compared the reversal of profound rocuronium-induced neuromuscular blockade in morbidly obese patients using doses of sugammadex based on four different weight corrections. One hundred morbidly obese patients, sc...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2011.06782.x
更新日期:2011-08-01 00:00:00
abstract::Nineteen consecutive patients undergoing total hip replacement under epidural anaesthesia were randomly divided into two groups. The treatment group received 1000 mg of ethamsylate intravenously before induction of anaesthesia. Blood lost during surgery was measured by a colorimetric technique. Closed suction drains w...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1979.tb06368.x
更新日期:1979-07-01 00:00:00
abstract::Acute risk change has been described as the difference in calculated mortality risk between the pre-operative and postoperative periods of cardiac surgery. We aimed to assess whether this was associated with long-term survival after cardiac surgery. We retrospectively analysed 22,570 cardiac surgical patients, with mi...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.13967
更新日期:2017-12-01 00:00:00
abstract::Nimodipine is widely used in patients with aneurysmal subarachnoid haemorrhage for the prevention and treatment of delayed ischaemic neurological deficits. Intravenous nimodipine has significant vasodilatory properties and may compromise the achievement of haemodynamic targets in patients who receive hypertensive hype...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章
doi:10.1111/j.1365-2044.1997.112-az0105.x
更新日期:1997-05-01 00:00:00
abstract::Transoesophageal echocardiography measures of systolic left ventricular function obtained during coronary artery bypass surgery are heavily influenced by alterations in loading conditions. No validation of these measurements against load independent indices obtained by pressure-volume loop analysis has been undertaken...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2006.04911.x
更新日期:2007-02-01 00:00:00
abstract::Twenty five patients were treated with an epidural blood patch for persistent headache, following a known or suspected dural puncture. Fifteen to 20 ml blood was injected into the epidural space through a catheter inserted one space away from the dural puncture. The catheter technique was useful in confirming the clin...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1985.tb10616.x
更新日期:1985-11-01 00:00:00
abstract::The effects of cardiopulmonary bypass and hypothermia were studied on the plasma concentration and metabolism of a continuous infusion of etomidate in six patients. Continuous etomidate infusions (20 micrograms/kg/minute) with analgesic cover may be a suitable anaesthetic for cardiac surgery. This rate of infusion pro...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1983.tb15183.x
更新日期:1983-07-01 00:00:00
abstract::Functional capacity is an integral component of the pre-operative evaluation of the cardiac patient for non-cardiac surgery. Stair climbing capacity has peri-operative prognostic importance. It may predict survival after lung resection and complications after major non-cardiac surgery. However, stair climbing cannot d...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2044.2005.04181.x
更新日期:2005-06-01 00:00:00
abstract::Sixty ASA physical status I and II, premedicated patients were administered propofol 2 mg x kg-1 and remifentanil 2 microg x kg-1 (group R), alfentanil 50 microg x kg-1 (group A) or suxamethonium 1 mg x kg-1 (group S) as a rapid bolus. One minute after study drug administration, tracheal intubation was performed. Intu...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2044.1999.01070.x
更新日期:1999-11-01 00:00:00
abstract::One hundred unpremedicated female patients of ASA grade 1 or 2 who underwent laparoscopy as outpatients were allocated randomly to one of four groups. All patients received general anaesthesia with fentanyl, thiopentone, halothane, nitrous oxide and oxygen; suxamethonium was given to facilitate tracheal intubation. In...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1990.tb14744.x
更新日期:1990-04-01 00:00:00
abstract::Dural puncture is rarely reported as a complication of stellate ganglion blockade. Breach of the dura occurred in the case described because of the anatomy of the cervical spine. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1990.tb14628.x
更新日期:1990-11-01 00:00:00
abstract::The elderly have the ethical and legal equivalence of younger adults, yet are treated differently by society. Numerous recent reports have exposed poor inpatient care resulting in part from institutional ageism, which has moral and legal implications for healthcare providers. Morally, there is an argument for positive...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/anae.12519
更新日期:2014-01-01 00:00:00
abstract::The use of fluid-warming systems is recommended for infusion rates > 500 ml.h-1 to avoid peri-operative hypothermia. Some fluid-warming devices use disposable aluminium-heated plates for heat transfer, but there is no protective coating to separate the fluid from the heated aluminium surface. It is unknown if this cou...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.14601
更新日期:2019-06-01 00:00:00
abstract::Clonidine has proved to be a clinically useful adjunct in clinical anaesthetic practice as well as in chronic pain therapy because it has both anaesthetic and analgesic-sparing activity. The more selective alpha-2 adrenoceptor agonists, dexmedetomidine and mivazerol, may also have a role in providing haemodynamic stab...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1046/j.1365-2044.1999.00659.x
更新日期:1999-02-01 00:00:00
abstract::The organic and psychological problems of patients suffering from chronic abdominal pain are described and three case histories of patients who had undergone multiple surgery for their abdominal pain are presented. All three were treated by lumbar sympathetic lysis, resulting in relief of their pain. The possible reas...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1981.tb10202.x
更新日期:1981-03-01 00:00:00
abstract::Acute cardiac herniation after radical pneumonectomy is extremely rare and is associated with an immediate mortality greater than 50%. We report a patient in whom cardiac herniation produced no signs or symptoms. The heart was returned to its correct position and the pericardial defect was repaired. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1046/j.1365-2044.1999.00611.x
更新日期:1999-06-01 00:00:00
abstract::Mortality remains high for patients on the waiting list for organ transplantation. A marked imbalance between the number of available organs and recipients that need to be transplanted persists. Organs from deceased donors are often declined due to perceived and actual suboptimal quality. Adequate donor management off...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/anae.15037
更新日期:2020-09-01 00:00:00
abstract::Major shoulder surgery can be extremely painful. Interscalene brachial plexus catheters provide excellent postoperative analgesia but are technically difficult to place. A new insulated Tuohy needle system for plexus catheterisation is now available. This prospective study examined its ease of use and the postoperativ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1046/j.1365-2044.2003.03184.x
更新日期:2003-06-01 00:00:00
abstract::We assessed the effectiveness of early patient-controlled oral analgesia compared with parenteral analgesia in a randomised controlled non-inferiority trial of women undergoing elective caesarean section under regional anaesthesia. Seventy-seven women received multimodal paracetamol, ketoprofen and morphine analgesia....
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/anae.13406
更新日期:2016-05-01 00:00:00
abstract::The haemodynamic changes following induction of anaesthesia with equipotent doses of propofol and thiopentone have been compared. Propofol caused a significant fall in arterial blood pressure and total peripheral resistance, with a slight fall in cardiac output. There were no changes in heart rate. Apart from an initi...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1985.tb10996.x
更新日期:1985-08-01 00:00:00
abstract::Spontaneous movement following injection of propofol at induction was studied in 303 patients. Two hundred patients were Caucasians and 103 were Asians. In a pilot study carried out prior to the main study, 26% of the Asians moved at induction as compared with 6% of the Caucasians. The patients were studied in relatio...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1996.tb07850.x
更新日期:1996-07-01 00:00:00
abstract::A 34-year-old female patient developed methaemoglobinaemia following a femoral nerve block using prilocaine. The concentrations of methaemoglobin in the blood of the next eight patients receiving this block were assayed, and found to be significantly increased above baseline concentrations, but very significantly less...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1992.tb04212.x
更新日期:1992-12-01 00:00:00
abstract::Duration of laryngoscopy must be kept as short as possible to prevent disturbances of oxygenation and ventilation. Because the factors associated with prolonged laryngoscopy are not well known, we studied 1000 patients undergoing tracheal intubation under general anaesthesia to determine the possible effects of their ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1046/j.1365-2044.2001.02084-5.x
更新日期:2001-12-01 00:00:00
abstract::The Datex 'Normac' infrared anaesthetic agent monitor has been evaluated for accuracy of calibration, stability and speed of response. Accuracy was assessed by comparing with a gas chromatograph calibrated using volumetric standards and was found to be very good for isoflurane and enflurane but was slightly less accur...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1985.tb10895.x
更新日期:1985-06-01 00:00:00
abstract::Two prototype agent-specific devices have been tested and neither in its present form is ideal. Filling of vaporisers may be delegated to inexperienced persons but the devices tested do not ensure that vaporisers can only be filled with the correct agent. Significant atmospheric pollution with the volatile anaesthetic...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1980.tb03923.x
更新日期:1980-08-01 00:00:00
abstract::The ability of a number of drugs to abolish the emergence delirium and unpleasant dreams which follow anaesthesia induced with 2 mg/kg ketamine was studied. These included three benzodiazepines, droperidol and 'neurolept' combinations and four commonly-used premedicants. When given intravenously 10 min before inductio...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1978.tb12412.x
更新日期:1978-04-01 00:00:00
abstract::A clinical trial was performed to compare the effects of intramuscular dihydrocodeine with caudal bupivacaine on postoperative pain and recovery in 181 children who had undergone either circumcision, inguinal herniotomy or orchidopexy performed under general anaesthesia. Linear analogues were used in assess level of c...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1982.tb01717.x
更新日期:1982-10-01 00:00:00