Abstract:
:Twenty-five women were investigated on the day after lower abdominal surgery in a single-blind non-cross-over trial to assess and compare the haemodynamic effects of intravenous injections of buprenorphine 0.3 mg and morphine 7.5 mg. Arterial blood pressure was measured by sphygmomanometry and cardiac output by thoracic impedance cardiography. Arterial blood pressure was significantly reduced following both drugs (p < 0.05), although the mean decrease in systolic arterial pressure was less than 8 mmHg. However, in one patient in each group the decrease was more than 20 mmHg. Cardiac output decreased but the mean reduction was less than 5%. The greatest individual decreases were 21% after buprenorphine and 30% after morphine. Myocardial contractility, assessed by systolic time indices, did not appear to change. There were no consistent differences in the haemodynamic effects of the two drugs.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Scott DH,Arthur GR,Scott DBdoi
10.1111/j.1365-2044.1980.tb04993.xsubject
Has Abstractpub_date
1980-10-01 00:00:00pages
957-61issue
10eissn
0003-2409issn
1365-2044journal_volume
35pub_type
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