Abstract:
STUDY OBJECTIVE:To evaluate whether isopropyl alcohol vapor is an effective treatment for postoperative nausea and vomiting. DESIGN:Double-blind, randomized, controlled study. SETTING:Pediatric surgery center. PATIENTS:91 ASA physical status I and II children age 6-16 years, scheduled to undergo general anesthesia and elective outpatient surgery. INTERVENTIONS:Subjects were randomized to inhale isopropyl alcohol or saline. The intervention was repeated up to three times. If postoperative nausea or vomiting persisted after three sequences, intravenous ondansetron was administered as rescue therapy. MEASUREMENTS AND MAIN RESULTS:Improvement in nausea was assessed using a visual analog scale, and improvement in vomiting was assessed using categorical analysis. After three treatment sequences, 65% of the children in the treatment group and 26% of the children in the control group had a significant reduction in the severity of either nausea or vomiting (p = 0.03). However, 54% of subjects in the treatment group and 80% of subjects in the control group had recurrent nausea or vomiting within 20 to 60 minutes. CONCLUSIONS:Under the conditions of this study, repetitive inhaled isopropyl alcohol only achieved a transient antiemetic effect in children with established postoperative nausea or vomiting following general anesthesia and surgery.
journal_name
J Clin Anesthjournal_title
Journal of clinical anesthesiaauthors
Wang SM,Hofstadter MB,Kain ZNdoi
10.1016/s0952-8180(99)00035-5subject
Has Abstractpub_date
1999-05-01 00:00:00pages
231-4issue
3eissn
0952-8180issn
1873-4529pii
S0952-8180(99)00035-5journal_volume
11pub_type
临床试验,杂志文章,随机对照试验abstract::We present a case of successful epidural analgesia/anesthesia for labor and cesarean section in a parturient who developed pseudotumor cerebri during her pregnancy and was managed with lumboperitoneal shunt secondary to her visual complication. ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(00)00133-1
更新日期:2000-05-01 00:00:00
abstract::Acute respiratory failure in the perioperative period represents a frequent challenge to the anesthesiologist. The differential diagnosis is extensive and includes alterations on the pulmonary parenchyma, pulmonary vessels, airway, and cardiac system. Occasionally, two or more pathophysiological process superimpose. W...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(01)00336-1
更新日期:2001-12-01 00:00:00
abstract::Fever is a common clinical problem in labor and delivery suites. It can result from a variety of infectious microorganisms, tissue trauma, malignancy, drug administration, and endocrine and immunologic disorders. Infection is the most common cause of fever, reflecting the effect of pyrogens on the hypothalamus. The di...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/s0952-8180(03)00081-3
更新日期:2003-09-01 00:00:00
abstract:STUDY OBJECTIVES:To determine whether the first-attempt tracheal intubation incidence using the GlideScope videolaryngoscope is higher in patients with predicted increased risk of difficult laryngoscopy, and to assess the ability of other a priori defined standard risk factors to predict first-attempt intubation succes...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2011.03.006
更新日期:2011-12-01 00:00:00
abstract:STUDY OBJECTIVES:To compare the onset and offset time (clinical duration), and intubating conditions obtained with rocuronium bromide 0.6 mg/kg and succinylcholine 1.0 mg/kg after induction with propofol and fentanyl; and to compare rocuronium with atracurium for maintenance during propofol anesthesia. DESIGN:Prospect...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0952-8180(00)00191-4
更新日期:2000-09-01 00:00:00
abstract:STUDY OBJECTIVE:To estimate the optimal endotracheal tube (ETT) length in orotracheally intubated patients. DESIGN:Prospective study. SETTING:Operating room of a medical center hospital. PATIENTS:293 ASA physical status I and II patients (150 male and 143 female), requiring general anesthesia and orotracheal intubat...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(02)00355-0
更新日期:2002-06-01 00:00:00
abstract:STUDY OBJECTIVE:To ascertain if coughing during emergence from general anesthesia can be suppressed with a modified endotracheal tube. DESIGN:Randomized, double-blind, controlled study. SETTING:Operating rooms at a university hospital. PATIENTS:46 adult ASA physical status I, II, and III patients requiring elective ...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0952-8180(01)00299-9
更新日期:2001-09-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the quality of analgesia and the severity of side effects of intrathecal morphine administered for a dose range of 0.0 to 0.4 mg for postcesarean analgesia with low-dose bupivacaine. DESIGN:Double-blind, randomized study. SETTING:University hospital. PATIENTS:100 ASA physical status I and...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2007.07.010
更新日期:2008-05-01 00:00:00
abstract:STUDY OBJECTIVES:To investigate the hypothesis that the combination of ondansetron and droperidol would be more effective than droperidol alone in reducing nausea and vomiting. DESIGN:Randomized, doubleblind study. SETTING:Magee-Womens Hospital, Pittsburgh, Pennsylvania. PATIENTS:160 healthy, ASA physical status I a...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0952-8180(97)00188-8
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVE:The American Society of Anesthesiologists physical status (ASA-PS) is associated with increased morbidity and mortality in the perioperative period. When surgeries are scheduled by surgeons and their staff at our large institution a presumed ASA-PS is chosen. This is because our institution (and, anecdotally,...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2017.02.002
更新日期:2017-05-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the safety and efficacy of monitored anesthesia care (MAC) in patients who undergo a novel treatment for hepatocellular cancer in which procedure-related hemodynamic instability is problematic. DESIGN:Nonrandomized open study. SETTING:University cancer center operating room. PATIENTS:Nine...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章
doi:10.1016/s0952-8180(97)00031-7
更新日期:1997-05-01 00:00:00
abstract:STUDY OBJECTIVE:To describe our systematic approach to securing the airway in patients with laryngeal tumors, developed over a 10-year period. DESIGN:Retrospective analysis. SETTING:University-affiliated veterans administration medical center. PATIENTS:Eight hundred one patients presenting for laryngeal tumor surger...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2004.12.019
更新日期:2005-12-01 00:00:00
abstract:STUDY OBJECTIVE:To investigate intracuff pressure changes in the ProSeal Laryngeal Mask Airway (PLMA) during 50% nitrous oxide (N₂O) anesthesia. DESIGN:Prospective, randomized study. SETTING:Operating room of a university-affiliated hospital. PATIENTS:40 ASA 1 and 2 children, aged 2 to 6 years, weighing 10-20 kg, un...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2010.09.004
更新日期:2011-05-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the effects of fresh gas flow on inspired gas composition during low-flow anesthesia. DESIGN:Randomized trial with 2-hour observation periods in patients assigned to one of three groups. SETTING:Inpatient surgery clinic at a medical center. PATIENTS:Thirty-six patients undergoing abdomin...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(92)90214-l
更新日期:1992-11-01 00:00:00
abstract:STUDY OBJECTIVE:To determine if intrathecal opioid decreases time to extubation after coronary artery bypass surgery without compromising postoperative analgesia. DESIGN:Prospective randomized trial. SETTING:Veterans Affairs Hospital. PATIENTS:21 ASA physical status III and IV men scheduled for elective coronary byp...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0952-8180(97)00081-0
更新日期:1997-08-01 00:00:00
abstract::von Willebrand disease (VWD) is the most common hereditary bleeding disorder in humans, with an estimated prevalence of 0.5% to 1%. Patients with VWD are at increased risk of perioperative bleeding complications. This review provides an evidence-based overview of VWD and its management during the perioperative period....
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,评审
doi:10.1016/j.jclinane.2011.02.003
更新日期:2011-08-01 00:00:00
abstract:STUDY OBJECTIVE:To test the hypothesis that midazolam potentiates thiopental sodium-induced unconsciousness. DESIGN:Randomized, double-blind study. SETTING:A university medical center. PATIENTS:Fifty nonpremedicated ASA physical status I and II adult patients scheduled for eye surgery. INTERVENTIONS:Intravenous (IV...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(91)90177-o
更新日期:1991-09-01 00:00:00
abstract:STUDY OBJECTIVE:Selecting candidates for residency positions is challenging and there is little research on the correlation between commonly used selection criteria and subsequent performance in anesthesiology. This study examined the association between the selection measures and post-recruitment performance in reside...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2017.03.052
更新日期:2017-06-01 00:00:00
abstract::A 13-year-old girl with Goltz's (Goltz-Gorlin) syndrome (focal dermal hypoplasia) and cloacal exstrophy underwent day surgery cystoscopy. During the administration of inhalation anesthesia by mask, persistent partial upper airway obstruction was noted. Direct laryngoscopy unexpectedly showed variously sized verrucous ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/0952-8180(91)90190-x
更新日期:1991-09-01 00:00:00
abstract::In conclusion, providing anesthesia for a small child undergoing craniofacial reconstructive surgery is an enormous challenge. Even with the most experienced pediatric anesthesiologist and pediatric surgeons, problems can develop suddenly and lead, as they did in this case, to serious morbidity and even death. It is d...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/s0952-8180(97)00162-1
更新日期:1997-11-01 00:00:00
abstract::A case of fulminant hepatic failure two days following an uneventful operation during isoflurane anesthesia is presented. Investigations included elevated bilirubin and serum transaminases in the absence of any other cause of hepatic dysfunction. The patient died on the fourth postoperative day. Subsequent postmortem ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2011.12.004
更新日期:2012-09-01 00:00:00
abstract::This article focuses on anesthesiology practice in the context of Belgian health care. The first part describes the organization of Belgian health care, the role of private and public initiatives, the division of responsibilities between the different health authorities, the financing mechanisms, and the central role ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/0952-8180(94)90081-7
更新日期:1994-07-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate whether children with Down Syndrome are at increased risk of bradycardia and hypotension during and following sevoflurane induction. DESIGN:Retrospective study. SETTING:University-affiliated children's hospital. MEASUREMENTS:The records of children with Down syndrome and a sample matched ...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2010.05.002
更新日期:2010-12-01 00:00:00
abstract:STUDY OBJECTIVE:To compare values for two whole blood viscoelastic coagulation tests, thromboelastography (TEG) and Sonoclot analysis (Sonoclot R Coagulation Analyzer, Sienco, Inc., Morrison, CO), between healthy parturients and nonparturients. DESIGN:Prospective study. SETTING:University hospital. PATIENTS:41 healt...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/0952-8180(93)90108-q
更新日期:1993-09-01 00:00:00
abstract::This is a case of systemic ropivacaine toxicity from a sciatic nerve catheter. A 20-year-old patient after heart transplant with poor systemic perfusion on hemodialysis and multiple medications experienced local anesthetic systemic toxicity 72 hours after placement of a peripheral nerve catheter. The case demonstrates...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2015.03.021
更新日期:2015-06-01 00:00:00
abstract::We report an 11-year-old male with undiagnosed myopathy, who developed cardiac arrest secondary to severe rhabdomyolysis and hyperkalemia following succinylcholine administration. The patient required extracorporeal membrane oxygenation support from which he was eventually weaned successfully. He died eleven days afte...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章
doi:10.1016/j.jclinane.2003.09.020
更新日期:2004-09-01 00:00:00
abstract:STUDY OBJECTIVE:To compare the postoperative analgesia of three different concentrations of levobupivacaine for ilioinguinal/iliohypogastric (II/IH) block in children undergoing inguinal hernia repair. DESIGN:Double-blind, prospective, randomized, controlled trial. SETTING:Operating room and postoperative recovery ar...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2008.10.012
更新日期:2009-09-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the effects of dexmedetomidine premedication on the minimum alveolar concentration of sevoflurane for tracheal intubation (MACTI) in children. DESIGN:Prospective, randomized, clinical comparison study. SETTING:Operating room of an academic hospital. PATIENTS:90 pediatric, ASA physical st...
journal_title:Journal of clinical anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jclinane.2013.12.012
更新日期:2014-06-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the opioid-sparing and analgesic effect of diclofenac sodium in ambulatory nonimmersion extracorporeal shock wave lithotripsy (ESWL). DESIGN:Randomized, double-blind, placebo-controlled study. SETTING:Large referral hospital. PATIENTS:Twenty-seven ASA physical status I and II patients wit...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(93)90142-2
更新日期:1993-03-01 00:00:00
abstract::Propofol, a phenol compound with a short elimination half-life, was compared with thiopental and isoflurane for induction and maintenance of general anesthesia in 60 consenting ASA I, II, and III patients. The study was randomized and open label in design. Hemodynamically, the propofol patients showed a mean +/- SEM d...
journal_title:Journal of clinical anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0952-8180(89)90026-3
更新日期:1989-01-01 00:00:00