Abstract:
:The opening of ortho-substituted phenyl oxiranes by borohydrides is described both in aqueous and solid phases. Some remarkable differences in the regioselectivity and inversion of enantioselectivity of oxirane ring-opening are reported. The results obtained are compared with previous studies and have allowed some factors governing the reactivity, the regio- and stereoselectivity of this reaction to be evaluated. Preferential orientations of the substrate included inside the cyclodextrin are proposed from these results. Copyright 1999 Wiley-Liss, Inc.
journal_name
Chiralityjournal_title
Chiralityauthors
Doussot J,Guy A,Siaugue JM,Ferroud C,Guieres AFdoi
10.1002/(SICI)1520-636X(1999)11:7<541::AID-CHIR5>3subject
Has Abstractpub_date
1999-01-01 00:00:00pages
541-5issue
7eissn
0899-0042issn
1520-636Xpii
10.1002/(SICI)1520-636X(1999)11:7<541::AID-CHIR5>3journal_volume
11pub_type
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