Abstract:
:The subject of this article is privacy and its relationship to the activities of health care organizations. Privacy is a good quality that each individual may possess. The quality of an individual's privacy is a personal determination. Although everyday life requires that we attempt to understand and protect the privacy of others, our efforts may be unsatisfactory despite our best intentions. If an individual believes that his or her privacy has been invaded, then it has been; no determination or opinion of a third party can alter that fact.
journal_name
Clin Lab Medjournal_title
Clinics in laboratory medicineauthors
Essin DJsubject
Has Abstractpub_date
1999-06-01 00:00:00pages
351-71, viissue
2eissn
0272-2712issn
1557-9832journal_volume
19pub_type
杂志文章abstract::Shiga toxin-producing Escherichia coli (STEC) are important enteric pathogens worldwide, causing diarrhea with or without blood visibly present and hemolytic uremic syndrome. STEC are unique among diarrheogenic E coli in producing Shiga toxin type 1 and type 2, the virulence factors responsible for bloody diarrhea and...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2009.11.001
更新日期:2010-03-01 00:00:00
abstract::Granulocytic sarcoma is a variant presentation of acute myeloblastic leukemia, occurring in extramedullary locations. It is uncommon, but it may occur at any site and at any age, which necessitates its inclusion in the differential diagnosis of all undifferentiated tumors. Histology, touch-imprint cytology, cytochemis...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1990-12-01 00:00:00
abstract::The era of prenatal screening for serious birth defects began in the 1970s with the discovery that amniotic fluid and maternal serum levels of alpha-fetoprotein (AFP) were increased in pregnancies affected by fetal open neural tube defects. Since then, prenatal screening has become a part of routine obstetric care. In...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/s0272-2712(03)00032-5
更新日期:2003-06-01 00:00:00
abstract::Bioregulators are naturally occurring organic compounds that regulate a multitude of biologic processes. Under natural circumstances, bioregulators are synthesized in minute quantities in a variety of living organisms and are essential for physiologic homeostasis. In the wrong hands, these compounds have the capabilit...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2006.03.007
更新日期:2006-06-01 00:00:00
abstract::I have reviewed many of the methods available for the assessment of fetal lung maturity. The difficulty of using diagnostic tests for diseases of low prevalence has been discussed. By reviewing the nature of the amniotic fluid surfactant material, and some of the principles underlying analytical methods, the bases of ...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract::Electron microscopy offers substantial aid in the diagnosis of gastrointestinal tract tumors, especially small-cell carcinoma and enterochromaffin-cell tumors. Tumors that are most difficult to classify by light microscopy--that is, poorly differentiated ones--may also have ultrastructural features by which the cell o...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract::DNA testing has revolutionized the forensic sciences. Forensic testing has continued to evolve, and now several methods are in use. The predominant methods of forensic DNA analysis are described, and their application in casework is summarized. The legal acceptance of this testing also is discussed. ...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1996-03-01 00:00:00
abstract::This article focuses on current clinical laboratory testing to diagnose Alzheimer disease and monitor its progression throughout its disease course. Several clinically available tests focus on analysis of amyloid and tau levels in cerebrospinal fluid as well as autosomal dominant and risk factor genes. Although the cu...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2020.05.003
更新日期:2020-09-01 00:00:00
abstract::One of the most vital functions of the vertebrates is to maintain hemostasis through coagulation and fibrinolysis. This is achieved by the interaction of vascular walls with blood components such as cells and proteins (coagulation factors, immunoglobulins, and complement). Deficiency of coagulation factors results in ...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1986-03-01 00:00:00
abstract::Molecular biological techniques have evolved expeditiously and in turn have been applied to the detection of infectious disease. Maturation of these technologies and their coupling with related technological advancement in fluorescence, electronics, digitization, nanodynamics, and sensors among others have afforded cl...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2018.02.004
更新日期:2018-06-01 00:00:00
abstract::Simple, inexpensive procedures for rapid identification of the common bacterial pathogens are outlined in detail. When the tests are judiciously applied, most isolates can be identified within minutes or hours, and strains that require more extensive testing for accurate identification will be recognized. ...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::With emerging antimicrobial resistance, rapid antimicrobial susceptibility testing (AST) is needed to provide early definitive therapeutic guidance to optimize patient outcome. Genotypic methods are fast, but can identify only a subset of known resistance elements. Phenotypic methods determine clinically predictive mi...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2019.04.001
更新日期:2019-09-01 00:00:00
abstract::Chromosome analysis is the genetic technique useful in evaluating endocrine disease. Indications for cytogenetic studies include suspected sex chromosomal aneuploidies as well as repeated fetal wastage. In patients with ambiguous genitalia, cytogenetic studies are mandatory, not only to provide information for assigni...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1984-12-01 00:00:00
abstract::The authors describe a system for collecting usage metrics from widely distributed automation systems. An application that records and stores usage data centrally, calculates run times, and charts the data was developed. Data were collected over 20 months from at least 28 workstations. The application was used to plot...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章
doi:10.1016/j.cll.2006.12.001
更新日期:2007-03-01 00:00:00
abstract::This article provides surgical pathologists an overview of health information systems (HISs): what they are, what they do, and how such systems relate to the practice of surgical pathology. Much of this article is dedicated to the electronic medical record. Information, in how it is captured, transmitted, and conveyed...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2015.09.012
更新日期:2016-03-01 00:00:00
abstract::There is growing evidence supporting the genetic variability outside of HLA system that is contributing to the variation in transplant outcomes. Determining novel predictors could help to identify patients at risk and tailor their immunosuppressive regimens. This article discusses the various single nucleotide polymor...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2018.10.002
更新日期:2019-03-01 00:00:00
abstract::Diseases due to nontuberculous mycobacteria are increasing in frequency, especially in patients with compromised immunity. A number of "new" mycobacterial species have been described in the last decade, largely as the result of the use of new tools to identify previously unrecognized mycobacteria found in the environm...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2004.05.011
更新日期:2004-09-01 00:00:00
abstract::Biochemical prenatal screening was initiated with the use of maternal serum alpha fetoprotein to screen for open neural tube defects. Screening now includes multiple marker and sequential screening protocols involving serum and ultrasound markers to screen for aneuploidy. Recently cell-free DNA screening for aneuploid...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2016.01.004
更新日期:2016-06-01 00:00:00
abstract::Variation in the genome of hepatitis B virus has been associated with a number of clinical parameters, but there is a paucity of functional data to show a causal relationship. For example, variants of the core and X genes have been linked with the pathogenesis of chronic hepatitis, viral replication efficiency, and se...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1996-06-01 00:00:00
abstract::Automated image processing analysis for leukocyte differential counting started 30 years ago principally as a mimic of the traditional microscopic method. Several types of systems were used in the 1970s and 1980s. In the late 1990s, two new image processing systems were developed with new technology for cell image ana...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/s0272-2712(03)00076-3
更新日期:2002-03-01 00:00:00
abstract::Normal thermogenesis requires a complex interaction between systems that generate and dissipate heat. Serving as director of thermogenesis, the hypothalamus activates the sympathetic nervous system along with the thyroid and adrenal glands to respond to changes in body temperature. Working in concert, these systems re...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2006.01.007
更新日期:2006-03-01 00:00:00
abstract::The optimal care of septic patients depends on the successful recovery of clinically relevant microorganisms from blood cultures and the timely reporting of organism identification and antimicrobial susceptibility testing (AST) results. Many preanalytic factors play a critical role in culturing microorganisms, and adv...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2020.07.001
更新日期:2020-12-01 00:00:00
abstract::The coccidians Cryptosporidium spp, Cyclospora cayetanensis, and Cystoisospora belli and the flagellate Giardia duodenalis are pathogenic protozoa associated with gastrointestinal manifestations. Diagnosis relies heavily on microscopy, and although ova-and-parasite examinations can detect Giardia and Cystoisospora, Cr...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2015.02.010
更新日期:2015-06-01 00:00:00
abstract::The importance of the phlogogenic effects of immune complexes in disease pathogenesis has been emphasized, but they also have a role in immunoregulation. We examined the effects of DNA: anti-DNA immune complexes, formed at different antigen:antibody ratios, on the ability of T cells to modulate DNA antibody production...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1988-06-01 00:00:00
abstract::Breast cancer is the leading cause of cancer mortality among women in developing countries. Timely and accurate histopathological diagnosis of breast cancer is critical to delivering high-quality breast cancer care to patients in low- and middle-income countries (LMIC). The most important prognostic factors in breast ...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2017.10.013
更新日期:2018-03-01 00:00:00
abstract::The interpretation of the total serum testosterone concentration is problematic because it is related directly to the serum SHBG concentration.Frequently, an estimate of the serum free testosterone concentration is obtained to better assess the clinical status of the patient. We reviewed five methods for the determina...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2004.01.010
更新日期:2004-03-01 00:00:00
abstract::Acute accidental iron poisoning is a common serious and potentially fatal intoxication in the young child. Approximately 1 per cent of such poisoning have a fatal outcome, and outcome is closely related to the early onset of coma or shock. Long-term prognosis is excellent for all survivors of the acute episode, althou...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1984-09-01 00:00:00
abstract::The cause of colorectal cancer (CRC) is multifactorial, with genetic, molecular, inflammatory, and environmental risk factors. Recently, the gut microbiota has been recognized as a new environmental contributor to CRC in both animal models and human studies. An additional interplay of the gut microbiome with inflammat...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:10.1016/j.cll.2014.08.002
更新日期:2014-12-01 00:00:00
abstract::Drug testing of patients in a psychiatric outpatient service is an effective way to identify patients who relapse into renewed use of drugs of abuse and in monitoring the effectiveness of ongoing medical and psychological therapy. Most of this testing involves the analysis of urine specimens with immunoassays. Hair te...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1998-12-01 00:00:00
abstract::Autoimmune aPL are associated with a well-defined clinical syndrome of vascular thromboses, recurrent fetal loss, thrombocytopenia, livedo reticularis, and valvular and neurologic abnormalities. A clinical diagnosis of SLE need not be present, and aPL syndrome in the absence of other well-defined autoimmune disease is...
journal_title:Clinics in laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1992-03-01 00:00:00