Diagnostic and Prognostic Laboratory Testing for Alzheimer Disease.

Abstract:

:This article focuses on current clinical laboratory testing to diagnose Alzheimer disease and monitor its progression throughout its disease course. Several clinically available tests focus on analysis of amyloid and tau levels in cerebrospinal fluid as well as autosomal dominant and risk factor genes. Although the current armament of clinical laboratory testing is limited by invasiveness of cerebrospinal fluid collection, rarity of autosomal dominant genetic mutations, and uncertainties of risk inherent in nonpenetrant genes, the field is poised to advance the clinical repertoire of laboratory diagnostic testing.

journal_name

Clin Lab Med

authors

Winder Z,Wilcock D,Jicha GA

doi

10.1016/j.cll.2020.05.003

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

289-303

issue

3

eissn

0272-2712

issn

1557-9832

pii

S0272-2712(20)30035-4

journal_volume

40

pub_type

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