Long-term results of laparoscopic splenectomy for immune thrombocytopenic purpura.

Abstract:

OBJECTIVE:To assess the results of laparoscopic splenectomy as a treatment for immune thrombocytopenic purpura (ITP). MATERIAL AND METHODS:We conducted a retrospective study of all patients who underwent laparoscopic splenectomy for ITP at our institution between August 1992 and May 1997. RESULTS:Of 27 patients who underwent attempted laparoscopic splenectomy for ITP at our institution during the study period, 26 had completion of the procedure without conversion to an open splenectomy. The median postoperative hospital stay was 1.5 days, and no postoperative deaths occurred. In one patient, pancreatitis developed postoperatively. In four patients, splenectomy failed--two initially and two subsequently--and reinstitution of medical therapy was necessary. The other patients have remained free of medication, and 19 patients have platelet counts greater than 100 x 10(9)/L. The 3-year actuarial success rate was 81.5%. Response to corticosteroid therapy preoperatively may be an indicator of success of splenectomy. CONCLUSION:Laparoscopic splenectomy is safe and allows prompt recovery. Long-term response rates are similar to those achieved with open splenectomy.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Harold KL,Schlinkert RT,Mann DK,Reeder CB,Noel P,Fitch TR,Braich TA,Camoriano JK

doi

10.4065/74.1.37

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

37-9

issue

1

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(11)64556-4

journal_volume

74

pub_type

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