Abstract：
:An improved gas chromatographic/mass spectrometric (GC/MS) assay is described for the quantitation of codeine and morphine as trimethylsyl (TMS) derivatives. The TMS derivatization of ketone-containing opiates results in the formation of multiple derivatives. Some of these products have retention times close to those of codeine-TMS and morphine-TMS. When the keto-opiates are present in samples assayed for codeine and morphine in urine, they can interfere with the quantitation of these commonly targeted opiates. The assay was improved with the addition of a pre-BSTFA derivatization step, whereby hydroxylamine was used to convert the keto-opiates into the corresponding oxime derivative. These derivatives were then reacted with BSTFA to form the TMS ethers and TMS oxime derivatives. The oxime step enabled production of single derivatives for hydrocodone and hydromorphone. In addition, the retention times for the oxime-TMS derivatives were increased so that they no longer elute near the targeted drugs of codeine and morphine. The addition of the oxime step does not affect the sylation of codeine and morphine, and the accuracy and precision of this assay were unaffected.
journal_name
J Forensic Scijournal_title
Journal of forensic sciencesauthors
Cremese M,Wu AH,Cassella G,O'Connor E,Rymut K,Hill DWsubject
Has Abstractpub_date
1998-11-01 00:00:00pages
1220-4issue
6eissn
0022-1198issn
1556-4029journal_volume
43pub_type
杂志文章abstract：:The fortuitous recovery of material trapped within the cavity of a hollow-point bullet at autopsy was demonstrated to be of evidentiary value. Analysis of this material, as well as that from hollow-point bullets from test-firings, showed that the contents, especially if in multiple layers, could be correlated with the...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1988-07-01 00:00:00
abstract：:Estimation of age in individuals has received considerable attention in forensic science, in which it is a widely used method for individual identification, together with paleo-demographic analyses to establish mortality patterns in past populations. The present investigation, which is a continuation of a previously p...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2006.00336.x
更新日期：2007-01-01 00:00:00
abstract：:To obtain a reliable estimation on the yield of illicit indoor cannabis cultivation in The Netherlands, cannabis plants confiscated by the police were used to determine the yield of dried female flower buds. The developmental stage of flower buds of the seized plants was described on a scale from 1 to 10 where the val...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2006.00228.x
更新日期：2006-09-01 00:00:00
abstract：:The male-specific Y-chromosomal short tandem repeat (STR) is a useful tool in forensic casework. The Y haplotype comprised of 16 loci, which is amplified simultaneously by AmpFlSTR(®) Yfiler(TM) PCR kit and provides strong exculpatory evidence in individual identification. We reported a rare Y-STR profile with a null ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2012.02145.x
更新日期：2012-11-01 00:00:00
abstract：:This paternity study was performed with trios in which the putative father was not the biological father (NBF), in order to evaluate the effectiveness of HLA-A and -B phenotyping for routine testing. All 372 generated trios had ABO, Rh, MNS, Kell, Duffy, Kidd and HLA (A and B) systems tested. HLA-A and -B phenotyping ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:Product tampering, as detailed by the Federal Anti-Tampering Act of 1983 (1), is a felony punishable by both fine and imprisonment. The rationale for product tampering ranges from pranks and attention seeking acts to extortion, terrorism, and homicide. One such case submitted for analysis involved four medical syringe...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Fatalities related to sporting events are predominantly caused by blunt force injuries especially due to the emotional involvement of crowd, but occasionally other types of trauma are reported as well. A case of very rare trauma caused by shooting with a hand-held parachute signal rocket during a football match is pre...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2008.00791.x
更新日期：2008-09-01 00:00:00
abstract：:The predictive utility of Hare, Hart, and Cox's Psychopathy Checklist Screening Version (PCL:SV) was assessed utilizing a sample of forensic psychiatric patients from Vernon State Hospital in Vernon, Texas. A sample of 55 patients were interviewed and rated on the PCL:SV. During a six month follow up, occurrences of s...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Closed-circuit television (CCTV) footage is used in criminal investigations to compare perpetrators with suspects. Usually, incomplete gait cycles are collected, making evidential gait analysis challenging. This study aimed to analyze the discriminatory power of joint angles throughout a gait cycle. Six sets from 12 m...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12322
更新日期：2014-03-01 00:00:00
abstract：:A sensitive, specific and simple color test for the improvised explosive urea nitrate is described. It is based on the formation of a red pigment upon the reaction between urea nitrate and p-dimethylaminocinnamaldehyde (p-DMAC) under neutral conditions. Urea itself, which is the starting material for urea nitrate, doe...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2005-05-01 00:00:00
abstract：POPULATION:The distribution of allele frequencies have been analyzed at two short tandem repeat (STR) loci FES and D2S1328 among five anthropologically distinct ethnic groups of India namely Ezhavas, Nairs, Arayas, Vishwakarma and Muslims. Muslims are religio-ethnic group while other populations mentioned above belong ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：:Bipartite patella is recognized as a developmental anomaly of ossification. Most of them are asymptomatic and are discovered incidentally. Bipartite patella is sometimes misdiagnosed as a patella fracture, because the x-ray images of both these conditions may appear very similar. In this case, the patient complained o...
journal_title：Journal of forensic sciences
pub_type：
doi：10.1111/1556-4029.13357
更新日期：2017-07-01 00:00:00
abstract：:There are no published reports that include both timely antemortem and postmortem carbamazepine concentrations after massive overdose. We report a fatal overdose of carbamazepine with both timely antemortem and postmortem carbamazepine concentrations. Carbamazepine concentrations were 47.7 mcg/mL 2 h antemortem and 53...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2001-11-01 00:00:00
abstract：:Infants born to diabetic mothers are at increased risk for symptomatic hypoglycemia and death after birth. A 36-year-old G4P3 mother with a history of gestational diabetes and newly diagnosed type II insulin-dependent diabetes gave birth at home, in the care of a midwife, to a macrosomic infant girl (10 lbs.). Several...
journal_title：Journal of forensic sciences
pub_type：
doi：10.1111/1556-4029.14247
更新日期：2020-05-01 00:00:00
abstract：:In bloodstain pattern analysis, the blood droplet volume and surface impact velocity play an important role, and many related experimental studies have been carried out. If an appropriate computational fluid dynamics (CFD) model that could solve bloodstain patterns, especially spine formation bloodstain patterns, can ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12484
更新日期：2014-11-01 00:00:00
abstract：:The physiological, psychological, and social consequences associated with illicit drug use are well documented. In addition to the effects directly related to the drug(s), the delivery mechanism can precipitate other serious health conditions. A case is reported where an individual stopped by law enforcement was disco...
journal_title：Journal of forensic sciences
pub_type：
doi：10.1111/1556-4029.13573
更新日期：2018-03-01 00:00:00
abstract：:In the era of Daubert and other judicial rulings pertaining to the acceptability of forensic evidence, it is increasingly important that experts are able to testify that their methods have been scientifically tested and that error rates and other factors relating to reliability have been published. The purpose of this...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：:The foot measurements are important in forensic field as they can be used as body height predictors for an individual. The morphology of human feet shows the variations and therefore the aim of this study was to find the relation between stature and foot measurements and to generate population-specific equations. We m...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12059
更新日期：2013-03-01 00:00:00
abstract：:We describe a massive fatal posterior myocardial infarct resulting from compression of the right coronary artery by a Teflon pledget granuloma in a patient who had undergone aortic valve replacement six months before death. Other iatrogenic causes of coronary artery occlusion or compression are discussed in this paper...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
abstract：:Mobile multi-detector computed tomography (MDCT) scanners are potentially available to temporary mortuaries and can be operational within 20 min of arrival. We describe, to our knowledge, the first use of mobile MDCT for a mass fatality incident. A mobile MDCT scanner attended the disaster mortuary after a five vehicl...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2007.00548.x
更新日期：2007-11-01 00:00:00
abstract：:Invasive fungal infections are a leading cause of morbidity and mortality in immunocompromised patients, especially in cases requiring a prolonged stay in the intensive care unit. A total of 99 yeast strains were isolated from 42 postmortem cases. In this study, virulence factors and antifungal susceptibility of these...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.13089
更新日期：2016-07-01 00:00:00
abstract：:From the works of Broca and Krogman to modern-day Jantz and Buikstra, the orbit has been used for both quantitative and qualitative sex and race estimation. This study evaluates the practical value of these estimations. Orbital height and breadth were measured to determine the orbital index and assess differences betw...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2011.01864.x
更新日期：2011-11-01 00:00:00
abstract：:Pair-matching of bilateral elements is a major component of resolving commingled remains both in forensic and bioarchaeological contexts. This study presents a new method of osteometric pair-matching of the lower limbs which relies on 3D digital models of the femur and tibia bones. The proposed method, which is accomp...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.14480
更新日期：2020-09-01 00:00:00
abstract：:Five diesel samples were analyzed by gas chromatography-mass spectrometry (GC-MS) using six GC temperature programs, aiming to investigate the effect of temperature program on association and discrimination of the samples. Temperature programs varied by ramp rate and incorporated one- or two-step temperature ramps. Pe...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2009.01234.x
更新日期：2010-01-01 00:00:00
abstract：:Recent court challenges have highlighted the need for statistical research on fingerprint identification. This paper proposes a model for computing likelihood ratios (LRs) to assess the evidential value of comparisons with any number of minutiae. The model considers minutiae type, direction and relative spatial relati...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2006.00327.x
更新日期：2007-01-01 00:00:00
abstract：:Mouth alcohol, if present in high enough concentrations, can falsely bias the accurate measurement of end-expiratory breath alcohol. Mouth alcohol will be eliminated over time, however, and can be modeled with a single term decaying exponential of the form: B0e-kt + C. It is important, however, to determine the model ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：:This study was designed to evaluate commonly used voice stress analyzers--in this case the layered voice analysis (LVA) system. The research protocol involved the use of a speech database containing materials recorded while highly controlled deception and stress levels were systematically varied. Subjects were 24 each...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2009.01026.x
更新日期：2009-05-01 00:00:00
abstract：:The main disadvantage to gunshot residue (GSR) particle analysis utilizing scanning electron microscope/energy dispersive X-ray (SEM/EDX) instrumentation has been the excessive operator time required for search and identification. This study uses an automated particle search and characterization program for unattended...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:This study investigated deliberate self-harm (DSH) in young inmates. The objectives are twofold: first, to identify the social and clinical characteristics of inmates who commit DSH; and secondly, to ascertain the types of personality who are vulnerable in order to be able to predict future inmates who may harm themse...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:The aim of the study was to determine the effect of gender, body mass index, and time on the width of friction ridge impressions in fingerprints and the content of sweat and sebum forming the print. The research showed that the friction ridge impressions of women are significantly wider than those of men, and this ten...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.13937
更新日期：2019-05-01 00:00:00
