Renal lesions in Von Hippel-Lindau disease: the benign, the malignant, the unknown.

Abstract:

OBJECTIVES:To describe the features and treatment of renal lesions in von Hippel-Lindau disease (VHL) from a series of patients, to highlight important issues in the management of these lesions. MATERIALS AND METHODS:We performed a retrospective study in 7 patients with VHL who underwent surgery for renal lesions between January 1990 and July 1996. The initial evaluation consisted of an abdominal CT scan and renal arteriography. RESULTS:The mean age of patients at the time of discovery was 38 (+/- 12.01 years). All cases were of type 1. Radiology assessment underestimated the gravity of the lesions in 5 patients. In all patients, unilateral surgery was performed with the kidney being conserved in 4 cases. Of the 44 lesions removed, 23 had signs of progressiveness (atypical or malignant cyst, renal cell carcinoma), most of the cancers were of low grade. 84% of the lesions did not exceed 3 cm and 48% were

journal_name

Eur Urol

journal_title

European urology

authors

Salomé F,Colombeau P,Fermeaux V,Cazaux P,Dumas JP,Pfeifer P,Moreau JJ,Richard S,Labrousse F

doi

10.1159/000019771

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

383-92

issue

5

eissn

0302-2838

issn

1873-7560

pii

eur34383

journal_volume

34

pub_type

杂志文章
  • Trends in the use of perioperative chemotherapy for localized and locally advanced muscle-invasive bladder cancer: a sign of changing tides.

    abstract:BACKGROUND:Despite the documented survival benefit conferred by neoadjuvant (NAC) and adjuvant chemotherapy (AC), there has been a slow adoption of guideline recommendations for the use of perioperative chemotherapy (POC) in patients with muscle-invasive bladder cancer (MIBC). OBJECTIVE:To evaluate temporal trends in ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2014.01.009

    authors: Reardon ZD,Patel SG,Zaid HB,Stimson CJ,Resnick MJ,Keegan KA,Barocas DA,Chang SS,Cookson MS

    更新日期:2015-01-01 00:00:00

  • Trigonal injection of botulinum toxin A in patients with refractory bladder pain syndrome/interstitial cystitis.

    abstract:BACKGROUND:Bladder pain syndrome/interstitial cystitis (BPS/IC) is a chronic disease without an effective treatment, characterized by pain during bladder filling. Most nociceptive bladder afferents course in the trigone. OBJECTIVE:To evaluate efficacy and tolerability of trigonal injection of botulinum toxin A (BoNTA)...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2010.02.031

    authors: Pinto R,Lopes T,Frias B,Silva A,Silva JA,Silva CM,Cruz C,Cruz F,Dinis P

    更新日期:2010-09-01 00:00:00

  • Changes in the sexual behavior of couples after prostatectomy. A prospective study.

    abstract::Sexual behavior after prostatectomy was observed in 90 couples, with a follow-up of 3-6 years. Retropubic prostatectomy was performed on 53 patients (58.7%), transvesical prostatectomy on 12 patients (13.7%), and transurethral prostatectomy on 25 patients (27.7%). In order to have a reliable figure of the sexual behav...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000472733

    authors: Cytron S,Simon D,Segenreich E,Leib Z,Servadio C

    更新日期:1987-01-01 00:00:00

  • Urethrogluteal fistula occurring after radical cystectomy for bladder cancer.

    abstract::We report on a patient who developed a urethrogluteal fistula 11 years following cystectomy performed for carcinoma of the bladder. The diagnosis was established by retrograde urethrography and fistulography. To the best of our knowledge, no previous case has been reported in the literature. ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000472777

    authors: Tasca A,Aragona F,Piazza R,Calabró A,Artibani W

    更新日期:1987-01-01 00:00:00

  • Maximal electrical stimulation in the treatment of unstable detrusor and urge incontinence.

    abstract::Ninety-one patients with unstable detrusor and urge incontinence were treated with maximal electrical stimulation. There were 17 dropouts. From the remaining 74 patients 51 were subjectively cured or significantly improved, this effect lasted for more than 6 weeks in 40. Objectively a significant decrease in frequency...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000463887

    authors: Fossberg E,Sørensen S,Ruutu M,Bakke A,Stien R,Henriksson L,Kinn AC

    更新日期:1990-01-01 00:00:00

  • The impact of androgen deprivation therapy on health related quality of life in asymptomatic men with lymph node positive prostate cancer.

    abstract:PURPOSE:To evaluate the impact of androgen deprivation on health related quality of life (HRQOL) in patients with asymptomatic lymph node positive prostatic carcinoma (LPPC). MATERIALS AND METHODS:HRQOL domains were measured, using standard instruments in 91 patients with histologically proven LPPC. Most patients were...

    journal_title:European urology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0302-2838(03)00208-2

    authors: van Andel G,Kurth KH

    更新日期:2003-08-01 00:00:00

  • Laparoscopic radical prostatectomy: technical and early oncological assessment of 40 operations.

    abstract:OBJECTIVE:To evaluate the technical feasibility, oncological efficacy and intraoperative and postoperative morbidity of laparoscopic radical prostatectomy. METHOD:We describe an original technique of laparoscopic radical prostatectomy performed in 40 patients between 26th January and 12th October, 1998. RESULTS:Radic...

    journal_title:European urology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000019921

    authors: Guillonneau B,Cathelineau X,Barret E,Rozet F,Vallancien G

    更新日期:1999-01-01 00:00:00

  • Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer.

    abstract:BACKGROUND:Metastatic castration-resistant prostate cancer (mCRPC) is the lethal form of the disease. Several recent studies have identified genomic alterations in mCRPC, but the clinical implications of these genomic alterations have not been fully elucidated. OBJECTIVE:To use whole-genome sequencing (WGS) to assess ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2019.03.020

    authors: Chen WS,Aggarwal R,Zhang L,Zhao SG,Thomas GV,Beer TM,Quigley DA,Foye A,Playdle D,Huang J,Lloyd P,Lu E,Sun D,Guan X,Rettig M,Gleave M,Evans CP,Youngren J,True L,Lara P,Kothari V,Xia Z,Chi KN,Reiter RE,Maher

    更新日期:2019-11-01 00:00:00

  • Late complications of ureteral stents.

    abstract:OBJECTIVE:To review morbidity and late complications of ureteral stent insertion and to specifically evaluate hydronephrosis as a radiologic finding of obstruction in the presence of an indwelling ureteral stent. METHODS:In this prospective study, we evaluated 110 stented kidneys in a group of 90 patients. Of 110 sten...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000020250

    authors: Ringel A,Richter S,Shalev M,Nissenkorn I

    更新日期:2000-07-01 00:00:00

  • A Four-kallikrein Panel Predicts High-grade Cancer on Biopsy: Independent Validation in a Community Cohort.

    abstract:BACKGROUND:A statistical model based on four kallikrein markers (total prostate-specific antigen [tPSA], free PSA [fPSA], intact PSA, and human kallikrein-related peptidase 2) in blood can predict risk of Gleason score ≥7 (high-grade) cancer at prostate biopsy. OBJECTIVE:To determine the value of this model in predict...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2015.04.028

    authors: Braun K,Sjoberg DD,Vickers AJ,Lilja H,Bjartell AS

    更新日期:2016-03-01 00:00:00

  • Adherence to European Association of Urology Guidelines on Prophylactic Antibiotics: An Important Step in Antimicrobial Stewardship.

    abstract:BACKGROUND:The evolution of resistant pathogens is a worldwide health crisis and adherence to European Association of Urology (EAU) guidelines on antibiotic prophylaxis may be an important way to improve antibiotic stewardship and reduce patient harm and costs. OBJECTIVE:To evaluate the prevalence of antibiotic-resist...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2015.05.010

    authors: Cai T,Verze P,Brugnolli A,Tiscione D,Luciani LG,Eccher C,Lanzafame P,Malossini G,Wagenlehner FM,Mirone V,Bjerklund Johansen TE,Pickard R,Bartoletti R

    更新日期:2016-02-01 00:00:00

  • Telesurgical laparoscopic radical prostatectomy. Initial experience.

    abstract:INTRODUCTION:Telepresence surgery offers theoretically to overcome two main problems of laparoscopic surgery, i.e. the limitation to only four degrees of freedom and the lack of stereovision. Since 1998, telesurgical minimally invasive procedures have been performed with the da Vinci system mainly for cardiac bypass su...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000049752

    authors: Rassweiler J,Frede T,Seemann O,Stock C,Sentker L

    更新日期:2001-07-01 00:00:00

  • Nephrosis with varicocele: probable renal vein thrombosis.

    abstract::A 3-year-old boy with relapsing nephrosis presented with a left sided varicocele. Echographic studies demonstrated enlargement of the left kidney, and there was delayed excretion on renal scintigraphy suggesting the presence of renal vein thrombosis. The varicocele resolved with remission of his nephrosis. ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000472498

    authors: Yazbeck S,Danais S,O'Regan S

    更新日期:1985-01-01 00:00:00

  • Prediction of functional outcomes after nerve-sparing radical prostatectomy: results of conditional survival analyses.

    abstract:BACKGROUND:In prostate cancer (PCa) patients treated with radical prostatectomy (RP), the rate of urinary continence (UC) and erectile function (EF) recovery may change significantly depending on the time interval between surgery and patient assessment. This effect, known as conditional survival, has not yet been asses...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2012.02.057

    authors: Abdollah F,Sun M,Suardi N,Gallina A,Bianchi M,Tutolo M,Passoni N,Tian Z,Salonia A,Colombo R,Rigatti P,Karakiewicz PI,Montorsi F,Briganti A

    更新日期:2012-07-01 00:00:00

  • The influence of various drugs on artificial oedema of the rat's bladder.

    abstract::An experimental oedema of the bladder wall was produced by electric coagulation current in 130 rats. The amount of oedema was calculated by determination of the difference between the weight of the freshly excised wet bladder and that after drying to constant weight. Thus, oedema of a fairly constant and reproducible ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000472035

    authors: Strohmenger P,Wenzel H

    更新日期:1976-01-01 00:00:00

  • Handling and pathology reporting of prostate biopsies.

    abstract::Appropriate handling and processing of prostate needle biopsies is critical for an optimal examination by pathologists. Reporting by pathologists should be accurate, unequivocal and concise, giving the information needed for the urologist. Quality parameters need to be developed to survey the performance of pathology ...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2004.04.006

    authors: Boccon-Gibod L,van der Kwast TH,Montironi R,Boccon-Gibod L,Bono A,European Society of Uropathology.,European Society of Pathology Uropathology Working Group.

    更新日期:2004-08-01 00:00:00

  • Cystinuria in children.

    abstract::7 children, 20 months to 11 years old, with cystinuria and renal calculi were studied. Surgical treatment and alpha-mercaptopropionylglycine (MPG) gave satisfactory results in 5 children. The causes of the recurrences in the other 2 children are discussed. MPG therapy is effective but can cause a nephrotic syndrome at...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473204

    authors: Pavanello L,Rizzoni G,Dussini N,Zacchello G,Passerini G,Tasca A,Pagano F

    更新日期:1981-01-01 00:00:00

  • Heparin binding growth factors and the control of teratoma cell proliferation.

    abstract::The role of basic fibroblast growth factor (bFGF) in the control of teratoma cell proliferation was examined. It was found that bFGF stimulates proliferation at low concentrations but induces cell migration at higher doses. These effects could be efficiently counteracted by addition of protamine sulphate. Moreover the...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474573

    authors: Granérus M,Welin A,Lundh B,Schofield PN,Ekström TJ,Engström W

    更新日期:1993-01-01 00:00:00

  • Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study.

    abstract:OBJECTIVE:To define the optimum tamoxifen dose for reducing bicalutamide (CASODEX) 150 mg monotherapy-induced breast events (ie, gynaecomastia or breast pain or both) without compromising disease control. METHODS:This was a double-blind, parallel-group, multicentre trial in which 282 patients with prostate cancer were...

    journal_title:European urology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.eururo.2007.01.031

    authors: Fradet Y,Egerdie B,Andersen M,Tammela TL,Nachabe M,Armstrong J,Morris T,Navani S

    更新日期:2007-07-01 00:00:00

  • Stool Microbiome Profiling of Patients with Metastatic Renal Cell Carcinoma Receiving Anti-PD-1 Immune Checkpoint Inhibitors.

    abstract::Preclinical models and early clinical data suggest an interplay between the gut microbiome and response to immunotherapy in solid tumors including metastatic renal cell carcinoma (mRCC). We sought to characterize the stool microbiome of mRCC patients receiving a checkpoint inhibitor (CPI) and to assess treatment-relat...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2020.07.011

    authors: Salgia NJ,Bergerot PG,Maia MC,Dizman N,Hsu J,Gillece JD,Folkerts M,Reining L,Trent J,Highlander SK,Pal SK

    更新日期:2020-10-01 00:00:00

  • Cardiovascular Mortality Following Short-term Androgen Deprivation in Clinically Localized Prostate Cancer: An Analysis of RTOG 94-08.

    abstract:BACKGROUND:Androgen deprivation therapy (ADT) is associated with coronary heart disease and diabetes in men with prostate cancer (PCa); however, controversy exists regarding ADT and cardiovascular mortality (CVM) with limited data for lower risk disease. OBJECTIVE:We conducted a hypothesis-generating retrospective ana...

    journal_title:European urology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.eururo.2015.08.027

    authors: Voog JC,Paulus R,Shipley WU,Smith MR,McGowan DG,Jones CU,Bahary JP,Zeitzer KL,Souhami L,Leibenhaut MH,Rotman M,Husain SM,Gore E,Raben A,Chafe S,Sandler HM,Efstathiou JA

    更新日期:2016-02-01 00:00:00

  • Trans-obturator vaginal tape (TOT) for female stress incontinence: one year follow-up in 120 patients.

    abstract:OBJECTIVES:The aim of this study was to evaluate the effectiveness of a new minimally invasive surgical procedure, the Trans-obturator Vaginal Tape (TOT) in the treatment of female urodynamic stress incontinence (USI) and to analyse functional results and quality of life after one year of follow up. MATERIAL AND METHO...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2005.08.003

    authors: Roumeguère T,Quackels T,Bollens R,de Groote A,Zlotta A,Bossche MV,Schulman C

    更新日期:2005-11-01 00:00:00

  • Retrosigmoid Versus Traditional Ileal Conduit for Urinary Diversion After Radical Cystectomy.

    abstract:BACKGROUND:Ureteroileal anastomotic stricture (UAS) after ileal conduit diversion occurs in a non-negligible proportion of patients undergoing radical cystectomy (RC). Surgical techniques aimed at preventing this potential complication are sought. OBJECTIVE:To describe our surgical technique of retrosigmoid ileal cond...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2018.06.023

    authors: Ficarra V,Giannarini G,Crestani A,Palumbo V,Rossanese M,Valotto C,Inferrera A,Pansadoro V

    更新日期:2019-02-01 00:00:00

  • Augmented reality: a new tool to improve surgical accuracy during laparoscopic partial nephrectomy? Preliminary in vitro and in vivo results.

    abstract:BACKGROUND:Use of an augmented reality (AR)-based soft tissue navigation system in urologic laparoscopic surgery is an evolving technique. OBJECTIVE:To evaluate a novel soft tissue navigation system developed to enhance the surgeon's perception and to provide decision-making guidance directly before initiation of kidn...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2009.05.017

    authors: Teber D,Guven S,Simpfendörfer T,Baumhauer M,Güven EO,Yencilek F,Gözen AS,Rassweiler J

    更新日期:2009-08-01 00:00:00

  • The impact of urinary extravasation after radical retropubic prostatectomy on urinary incontinence and anastomotic strictures.

    abstract:OBJECTIVE:The aim of this study was to determine the relevance of urinary extravasation as proven by cystogram 18 days after radical retropubic prostatectomy for the degree of postoperative urinary incontinence and the incidence of anastomotic strictures. PATIENTS AND METHODS:A total of 225 patients underwent radical ...

    journal_title:European urology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000067995

    authors: Schatzl G,Madersbacher S,Hofbauer J,Pycha A,Reiter WJ,Svolba G,Marberger M

    更新日期:1999-09-01 00:00:00

  • Present status of undergraduate urological education in Turkey: is standardization necessary?

    abstract::23 medical faculties exist in Turkey at the moment and 2 others are being established. Considering that all these faculties run their own programs independently, different education systems might effect the standard of doctors and health care. All of the new graduates in this country face a centralized examination for...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000464040

    authors: Akdaş A,Simşek F,Ilker Y

    更新日期:1990-01-01 00:00:00

  • Medical therapy to facilitate the passage of stones: what is the evidence?

    abstract:CONTEXT:Medical expulsive therapy (MET) for urolithiasis has gained increasing attention in the last years. It has been suggested that the administration of alpha-adrenoreceptor antagonists (alpha-blockers) or calcium channel blockers augments stone expulsion rates and reduces colic events. OBJECTIVE:To evaluate the e...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2009.06.012

    authors: Seitz C,Liatsikos E,Porpiglia F,Tiselius HG,Zwergel U

    更新日期:2009-09-01 00:00:00

  • Duration of Androgen Deprivation Therapy Influences Outcomes for Patients Receiving Radiation Therapy Following Radical Prostatectomy.

    abstract:BACKGROUND:Limited data exist to guide the use of androgen deprivation therapy (ADT) for men treated with radiation therapy (RT) after radical prostatectomy (RP). The optimal duration of ADT in this setting is unknown. OBJECTIVE:To determine if the duration of ADT influences clinical outcomes for men receiving post-RP...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2015.05.009

    authors: Jackson WC,Schipper MJ,Johnson SB,Foster C,Li D,Sandler HM,Palapattu GS,Hamstra DA,Feng FY

    更新日期:2016-01-01 00:00:00

  • Intrafascial nerve-sparing endoscopic extraperitoneal radical prostatectomy.

    abstract:OBJECTIVES:Based on our recently published anatomic studies, we present the most recent refinement of the endoscopic extraperitoneal radical prostatectomy (EERPE), the intrafascial nerve-sparing EERPE (nsEERPE). METHODS:As part of the intrafascial technique, the dissection plane is directly on the prostatic capsule, f...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2007.11.047

    authors: Stolzenburg JU,Rabenalt R,Do M,Schwalenberg T,Winkler M,Dietel A,Liatsikos E

    更新日期:2008-05-01 00:00:00

  • Study of the association between ischemic heart disease and use of alpha-blockers and finasteride indicated for the treatment of benign prostatic hyperplasia.

    abstract:OBJECTIVE:Given the high possibility of co-occurrence of benign prostatic hyperplasia (BPH) and cardiovascular disease, we evaluated whether patients using BPH drugs are at an increased risk of acute hospital admission for ischemic heart disease (IHD). METHODS:A nested case control study within a cohort of 4414 men (a...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/s0302-2838(02)00273-7

    authors: Souverein PC,Herings RM,Man in 't Veld AJ,de la Rosette JJ,Farmer RD,Leufkens HG

    更新日期:2002-09-01 00:00:00