Selective synaptic plasticity within the cerebellar cortex following complex motor skill learning.

abstract：:Acetylcholine plays an important role in regulating the processing of sensory stimuli, and understanding its specific cellular actions is critical to understanding how sensory cortex develops and functions in different behavioral states. Here we review recent work on the cellular effects of nicotinic receptor activati...

journal_title：Neurobiology of learning and memory

authors： Metherate R,Hsieh CY

更新日期：2003-11-01 00:00:00

abstract：:Recent evidence suggests that an interaction of noradrenaline (NE) and cortisol (CORT) during encoding leads to greater consolidation of emotional memories. Convergent models of posttraumatic stress disorder (PTSD) suggest the release of CORT and NE lead to greater intrusive memories in PTSD. This study examined the e...

journal_title：Neurobiology of learning and memory

authors： Nicholson EL,Bryant RA,Felmingham KL

更新日期：2014-07-01 00:00:00

abstract：:Activation of N-methyl-d-aspartate (NMDA) receptors has been hypothesized to mediate certain forms of learning and memory. This hypothesis is based on the ability of competitive and uncompetitive NMDA receptor antagonists to disrupt learning. We investigated the effects of glycine site antagonists and partial agonists...

journal_title：Neurobiology of learning and memory

authors： Viu E,Zapata A,Capdevila J,Skolnick P,Trullas R

更新日期：2000-09-01 00:00:00

abstract：:Considerable work demonstrates that Pavlovian fear conditioning depends on N-methyl-D-aspartate (NMDA) receptor-dependent plasticity within the amygdala. In addition, the bed nucleus of the stria terminalis (BNST) has also been implicated in fear conditioning, particularly in the expression of fear to poor predictors ...

journal_title：Neurobiology of learning and memory

authors： Ressler RL,Goode TD,Evemy C,Maren S

更新日期：2020-10-01 00:00:00

abstract：:Transgenic mouse models of Alzheimer's disease (AD) with nonphysiologic overexpression of amyloid precursor protein (APP) exhibit various unnatural symptoms/dysfunctions. To overcome this issue, mice with single humanized App knock-in (KI) carrying Swedish (NL), Beyreuther/Iberian (F), and Arctic (G) mutations in diff...

journal_title：Neurobiology of learning and memory

authors： Masuda A,Kobayashi Y,Kogo N,Saito T,Saido TC,Itohara S

更新日期：2016-11-01 00:00:00

abstract：:We developed a single-trial cue-location memory task in which rats experienced an auditory cue while exploring an environment. They then recalled and avoided the sound origination point after the cue was paired with shock in a separate context. Subjects with medial prefrontal cortical (mPFC) lesions made no such avoid...

journal_title：Neurobiology of learning and memory

authors： Rawson T,O'Kane M,Talk A

更新日期：2010-01-01 00:00:00

abstract：:Although no single widely accepted animal model of PTSD has been established to date, the single prolonged stress (SPS) animal model has been partially validated as a model for PTSD. SPS rats mimic the pathophysiological abnormalities and behavioral characteristics of PTSD, such as enhanced fear response to the trauma...

journal_title：Neurobiology of learning and memory

authors： Mirshekar M,Abrari K,Goudarzi I,Rashidy-Pour A

更新日期：2013-05-01 00:00:00

abstract：:Testosterone (T) may enhance cognitive performance. However, its mechanisms are not well understood. First, we hypothesized that if T's effects are mediated in part through actions of its 5alpha-reduced metabolites, dihydrotestosterone (DHT) and/or 3alpha-androstanediol (3alpha-diol) in the hippocampus, then T, DHT, a...

journal_title：Neurobiology of learning and memory

authors： Edinger KL,Frye CA

更新日期：2007-01-01 00:00:00

abstract：:Recent research has begun to demonstrate that specific subunits of GABA(A) receptors may be involved in the normal expression of specific behaviors. The present research used mice with GABA(A) receptors whose alpha1 subunits contained mutations of serine 270 to histidine and leucine 277 to alanine in the TM2 region. T...

journal_title：Neurobiology of learning and memory

authors： Berry RB,Werner DF,Wang X,Jablonski MM,Homanics GE,Mittleman G,Matthews DB

更新日期：2008-10-01 00:00:00

abstract：:A common conceptualization of the organization of memory systems in brain is that different types of memory are mediated by distinct neural systems. Strong support for this view comes from studies that show double (or triple) dissociations between spatial, response, and emotional memories following selective lesions o...

journal_title：Neurobiology of learning and memory

authors： Mizumori SJ,Yeshenko O,Gill KM,Davis DM

更新日期：2004-11-01 00:00:00

abstract：:Sleep is involved in both the consolidation of discrete episodes, as well as the generalisation of acquired memories into schemata. Here, we have isolated early versus late periods of sleep in order to replicate previous behavioural findings and to demonstrate: i) that distinct sleep and sleep electroencephalography (...

journal_title：Neurobiology of learning and memory

authors： Chatburn A,Lushington K,Kohler MJ

更新日期：2021-01-15 00:00:00

abstract：:Expression of immediate-early genes, like Egr-1, has been shown to be induced by activity-dependent synaptic plasticity or behavioral training and is widely thought to play an important role in long-term memory (LTM) formation. However, little is known about the role of Egr-1 in the maintenance of memory storage. Here...

journal_title：Neurobiology of learning and memory

authors： Katche C,Goldin A,Gonzalez C,Bekinschtein P,Medina JH

更新日期：2012-10-01 00:00:00

abstract：:The entorhinal cortex (EC) has been shown to be an integral piece of the hippocampal memory system. It sits in a unique position within the brain with strong, intricate, reciprocal connectivity with the hippocampus as well as a vast array of neocortical regions. Topographical patterns of afferent and efferent projecti...

journal_title：Neurobiology of learning and memory

authors： Morrissey MD,Takehara-Nishiuchi K

更新日期：2014-11-01 00:00:00

abstract：:The present study examined the effects of posttraining ethanol administration upon retention of an appetitive task using a variety of retention behaviors associated with the task. Male C57BL/6J mice were individually trained to find a cheese pellet placed in the corner of an open field. Five behavioral measures were u...

journal_title：Neurobiology of learning and memory

authors： Ladner CJ,Babbini M,Davies DL,Parker ES,Alkana RL

更新日期：2001-01-01 00:00:00

abstract：:Human drug addiction is a complex disorder, in which exogenous substances are able to recruit and maintain behaviors involved in drug taking. Many drugs that are addictive in humans are able to act on natural brain systems for learning and memory, and while many memory systems may be affected by addictive drugs, work ...

journal_title：Neurobiology of learning and memory

authors： Schmitzer-Torbert N,Apostolidis S,Amoa R,O'Rear C,Kaster M,Stowers J,Ritz R

更新日期：2015-02-01 00:00:00

abstract：:In spite of evidence about negative effects of Nandrolone Decanoate (ND) on cognitive and memory performance, the underlying mechanisms are complex and have remained unclear. This research examines the role of Calcineurin in synaptic plasticity and memory storage impairment in ND administrated adolescent male rats. Fo...

journal_title：Neurobiology of learning and memory

authors： Moradpour F,Moazedi AA,Pourmotabbed A,Zarei F

更新日期：2019-09-01 00:00:00

abstract：:The unique polarity of neurons requires that synaptic inputs are relayed to the nucleus to trigger changes in gene expression. This long distance signaling process is crucial for the function and survival of neuronal circuits. To that end, neurons have developed multiple modes of signal transmission from the synapse t...

journal_title：Neurobiology of learning and memory

authors： Lim AF,Lim WL,Ch'ng TH

更新日期：2017-02-01 00:00:00

abstract：:Based on computational models of the hippocampus, it has been suggested that a possible mechanism for memory retrieval is pattern completion, wherein an autoassociative network recalls previous patterns of activity given noisy or degraded cues. However, there are few behavioral data examining pattern completion per se...

journal_title：Neurobiology of learning and memory

authors： Kirwan CB,Gilbert PE,Kesner RP

更新日期：2005-01-01 00:00:00

abstract：:Non-selective inhibition of histone deacetylases (HDACs), enzymes that remove acetyl groups from histone core proteins, enhances cognition and NMDAR-dependent long-term potentiation at hippocampal CA3-CA1 synapses. It is not known whether this is a general mechanism by which HDACs modulate plasticity at other hippocam...

journal_title：Neurobiology of learning and memory

authors： Franklin AV,Rusche JR,McMahon LL

更新日期：2014-10-01 00:00:00

abstract：:Over the last decade, the interest in transcranial direct current stimulation (tDCS) has continued to increase, along with consideration of how it affects neuroplasticity mechanisms in the brain. Both human and animal studies have demonstrated numerous benefits and, although its application has increased, the neurophy...

journal_title：Neurobiology of learning and memory

authors： Stafford J,Brownlow ML,Qualley A,Jankord R

更新日期：2018-04-01 00:00:00

abstract：:Environmental stimuli during neonatal periods play an important role in the development of cognitive function. In this study, we examined the long-term effects of neonatal tactile stimulation (TS) on spatial working memory (SWM) and related mechanisms. We also investigated whether TS-induced effects could be counterac...

journal_title：Neurobiology of learning and memory

authors： Zhang M,Cai JX

更新日期：2008-05-01 00:00:00

abstract：:The present experiments examined the effects of posttraining intra-dorsal striatal (i.e., caudate-putamen) injections of the phospholipid methylcarbamyl platelet-activating factor (mc-PAF) and the platelet-activating factor (PAF) antagonist BN 52021 on memory using a striatal-dependent cued water maze task. Male Long-...

journal_title：Neurobiology of learning and memory

authors： Packard MG,Teather LA,Bazan NG

更新日期：1996-09-01 00:00:00

abstract：:The cholinergic system has consistently been implicated in Pavlovian fear conditioning. Considerable work has been done to localize specific nicotinic receptor subtypes in the hippocampus and determine their functional importance; however, the specific function of many of these subtypes has yet to be determined. An al...

journal_title：Neurobiology of learning and memory

authors： Vago DR,Kesner RP

更新日期：2007-03-01 00:00:00

abstract：:Adolescence is characterized by major developmental changes that may render the individual vulnerable to stress and the development of psychopathologies in a sex-specific manner. Earlier we reported lower anxiety-like behavior and higher risk-taking and novelty seeking in rats previously exposed to peri-pubertal stres...

journal_title：Neurobiology of learning and memory

authors： Toledo-Rodriguez M,Pitiot A,Paus T,Sandi C

更新日期：2012-07-01 00:00:00

abstract：:Taste aversion learning is induced through two different behavioral procedures: a short-term or concurrent (two-daily flavors) and a long-term or sequential (one-daily flavor) procedure. For the concurrent group of animals, two gustatory/olfactory stimuli are presented separately but at the same time on a daily basis....

journal_title：Neurobiology of learning and memory

authors： Mediavilla C,Molina F,Puerto A

更新日期：2001-09-01 00:00:00

abstract：:Transcriptional changes in the hippocampus are required for memory formation, and these changes are regulated by numerous post-translational modifications of chromatin-associated proteins. One of the epigenetic marks that has been implicated in memory formation is histone 3 lysine 4 trimethylation (H3K4me3), and this ...

journal_title：Neurobiology of learning and memory

authors： Collins BE,Sweatt JD,Greer CB

更新日期：2019-05-01 00:00:00

abstract：:Nitric oxide (NO) is a highly labile chemical messenger which has previously been implicated in memory processes in a variety of learning paradigms and species. However, there is only limited evidence to suggest which enzymes are acted upon by NO during the formation of memory. The present study investigates the role ...

journal_title：Neurobiology of learning and memory

authors： Edwards TM,Rickard NS,Ng KT

更新日期：2002-05-01 00:00:00

abstract：:Effects of estradiol benzoate (EB), ERα-selective agonist, propyl pyrazole triol (PPT) and ERβ-selective agonists, diarylpropionitrile (DPN) and Compound 19 (C-19) on memory were investigated in OVX rats using object recognition (OR) and placement (OP) memory tasks. Treatments were acute (behavior 4h later) or sub chr...

journal_title：Neurobiology of learning and memory

authors： Jacome LF,Gautreaux C,Inagaki T,Mohan G,Alves S,Lubbers LS,Luine V

更新日期：2010-11-01 00:00:00

abstract：:Differences in cytoarchitectural organization and connectivity distinguishes granular (or area 29, A29) and dysgranular (or area 30, A30) subdivisions of the retrosplenial cortex (RSC). Although increasing evidence supports the participation of RSC in contextual fear learning and memory, the contribution of each RSC s...

journal_title：Neurobiology of learning and memory

authors： Sigwald EL,de Olmos S,Lorenzo A

更新日期：2020-05-01 00:00:00

abstract：:The present work shows that the dorsomedial telencephalic pallium of teleost fish, proposed as homologous to the amygdala of mammals, is involved in taste aversion learning (TAL). To analyze the behavioral properties of TAL in goldfish, in Experiment 1, we used a delayed procedure similar to that employed with mammals...

journal_title：Neurobiology of learning and memory

authors： Martín I,Gómez A,Salas C,Puerto A,Rodríguez F

更新日期：2011-09-01 00:00:00