Abstract:
:We experienced two rare cases of pernicious anemia that presented in the course of mycosis fungoides in elderly males. Pernicious anemia has recently been reported to be caused by autoimmune gastritis that produces autoantibodies to gastric parietal cells and intrinsic factor. Immunological abnormalities in mycosis fungoides are reported to induce autoimmune diseases (i.e., autoimmune hemolytic anemia, anti-phospholipid antibody syndrome, arthritis, myasthenia gravis, necrotizing vasculitis, and vitiligo); the pernicious anemia in our two patients may have been closely related to the mycosis fungoides.
journal_name
Am J Hematoljournal_title
American journal of hematologyauthors
Saitoh T,Murakami H,Hayashi K,Matsushima T,Tamura J,Karasawa M,Naruse T,Tsuchiya Jdoi
10.1002/(sici)1096-8652(199806)58:2<127::aid-ajh7>subject
Has Abstractpub_date
1998-06-01 00:00:00pages
127-9issue
2eissn
0361-8609issn
1096-8652pii
10.1002/(SICI)1096-8652(199806)58:2<127::AID-AJH7>journal_volume
58pub_type
杂志文章abstract::Thrombotic thrombocytopenic purpura (TTP) is a microangiopathy syndrome caused by a congenital or acquired deficiency of ADAMTS13, a plasma metalloprotease that cleaves von Willebrand factor (VWF) and thus prevents the formation of platelet-rich thrombi in the microcirculation. TTP can be fatal if not appropriately an...
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