Diagnostic value of albumin gene expression in liver tumors: case report and review of the literature.

Abstract:

:Management of a solitary liver mass necessitates reliable distinction between primary hepatocellular carcinoma and metastatic lesions. The histologic differentiation can be difficult even with special stains such as alpha-fetoprotein, cytokeratin, and carcinoembryonic antigen. Albumin is a specific product of hepatocytes, and in situ hybridization to reveal albumin messenger RNA (mRNA) is highly specific and sensitive for the diagnosis of primary hepatocellular carcinoma. This technique can be used on histopathologic specimens and in cytologic diagnosis. Herein we describe a patient with synchronous renal and hepatic masses, in whom the distinction had to be made between metastatic renal cell carcinoma and two separate primary tumors--one in the liver and one in the kidney. In situ hybridization for albumin mRNA proved helpful in making this distinction. In addition, we review the literature on the diagnostic use of albumin gene expression in liver tumors.

journal_name

Mayo Clin Proc

journal_title

Mayo Clinic proceedings

authors

Rajkumar SV,Richardson RL,Goellner JR

doi

10.4065/73.6.533

subject

Has Abstract

pub_date

1998-06-01 00:00:00

pages

533-6

issue

6

eissn

0025-6196

issn

1942-5546

pii

S0025-6196(11)63519-2

journal_volume

73

pub_type

杂志文章,评审
  • Management of urinary retention: rapid versus gradual decompression and risk of complications.

    abstract::The literature was reviewed to quantify the risk of complications related to the relief of obstruction in urinary retention. We also sought to determine whether the risk of complications is higher with rapid or gradual decompression (or "clamping") of the obstructed urinary bladder. The medical literature was identifi...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/S0025-6196(11)63368-5

    authors: Nyman MA,Schwenk NM,Silverstein MD

    更新日期:1997-10-01 00:00:00

  • Recently developed elastomers for facial prostheses.

    abstract::Ever since ancient times, man has been searching for the proper artificial substitute for living tissue. This has been a most frustrating and challenging task for the scientific community involved. Prosthetic restoration is the only alternative to reconstructive surgery for the facially deformed. This paper reviews th...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Gonzalez JB

    更新日期:1978-07-01 00:00:00

  • Carotid sinus hypersensitivity and syncope.

    abstract::The patient with a hypersensitive carotid sinus reflex and syncope may pose special challenges in evaluation and treatment. Specifically, although the finding of carotid sinus hypersensitivity may indeed indicate an exaggerated vagal tone that causes syncope, it may also be a chance association in a patient with synco...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)62417-3

    authors: Sugrue DD,Wood DL,McGoon MD

    更新日期:1984-09-01 00:00:00

  • Evolving era of multidimensional medical imaging.

    abstract::Currently, computer-assisted imaging can visualize very fast or very slow nonvisible motion events. We can create measurable geometric representations of physiology, including transformation, blood flow velocity, perfusion, pressure, contractility, image features, electricity, metabolism, and a vast number of other co...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/74.4.399

    authors: Seward JB,Belohlavek M,Kinter TM,Greenleaf JF

    更新日期:1999-04-01 00:00:00

  • Congenital absence of the portal vein.

    abstract::A 4 1/2-year-old girl is described in whom the portal vein is absent and the venous return from the gastrointestinal tract, spleen, and pancreas is through the left renal vein into the inferior vena cava. She had a hepatoblastoma, which was treated surgically by right hepatic lobectomy. Regeneration occurred in the re...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Marois D,van Heerden JA,Carpenter HA,Sheedy PF 2nd

    更新日期:1979-01-01 00:00:00

  • Radical Prostatectomy Trends in the United States: 1998 to 2011.

    abstract:OBJECTIVE:To determine the incidence and distribution of radical prostatectomy (RP) in the United States over time. PATIENTS AND METHODS:We conducted a serial cross-sectional analysis of time trends using the Nationwide Inpatient Sample of adult men older than 45 years who underwent RP between January 1, 1998, and Dec...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2015.09.018

    authors: Tyson MD 2nd,Andrews PE,Ferrigni RF,Humphreys MR,Parker AS,Castle EP

    更新日期:2016-01-01 00:00:00

  • Nonconvulsive status epilepticus in a patient with leptomeningeal cancer.

    abstract::A 56-year-old man sought medical assistance because of recurrent nonconvulsive status epilepticus without a history of prior seizure activity. Examination of the cerebrospinal fluid disclosed leptomeningeal cancer. To our knowledge, the association of partial complex status epilepticus and leptomeningeal cancer has no...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)62337-4

    authors: Broderick JP,Cascino TL

    更新日期:1987-09-01 00:00:00

  • Lymphoma associated with human immunodeficiency virus infection.

    abstract:OBJECTIVE:To describe lymphoma associated with human immunodeficiency virus (HIV) infection. DESIGN:A review of HIV-related lymphoma and its associated epidemiology, etiopathogenesis, and clinicopathologic characteristics is presented. Major studies of therapeutic regimens for HIV-related lymphoma are discussed. Facto...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/70.7.665

    authors: Wang CY,Snow JL,Su WP

    更新日期:1995-07-01 00:00:00

  • Constrictive pericarditis: assessment of current diagnostic procedures.

    abstract::Constrictive pericarditis frequently poses a diagnostic challenge because of its varied manifestations. Accurate diagnosis is essential, however, because surgical decortication may yield excellent clinical results. Although new diagnostic procedures have helped the clinician to diagnose constrictive pericarditis, the ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)60850-7

    authors: Nishimura RA,Connolly DC,Parkin TW,Stanson AW

    更新日期:1985-06-01 00:00:00

  • Symptomatic hyperthyroidism in a patient taking the dietary supplement tiratricol.

    abstract::An 87-year-old woman was referred for evaluation of nervousness, tremor, insomnia, and fatigue of 2 months' duration. Initial laboratory evaluation revealed a suppressed thyrotropin level and an elevated triiodothyronine level. A review of her medications revealed that she had started taking several dietary supplement...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/77.6.587

    authors: Bauer BA,Elkin PL,Erickson D,Klee GG,Brennan MD

    更新日期:2002-06-01 00:00:00

  • Cataracts and cataract operations (1).

    abstract::Cataract operations are commonly performed in either a primary-care or a tertiary-care center. A plethora of information (some of which is unfounded) has been disseminated in the lay news media about the advances in the surgical techniques of cataract removal. This article reviews some of the recent concepts about the...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/s0025-6196(12)61494-3

    authors: Liesegang TJ

    更新日期:1984-08-01 00:00:00

  • Intraoperative hyperglycemia and perioperative outcomes in cardiac surgery patients.

    abstract:OBJECTIVE:To estimate the magnitude of association between intraoperative hyperglycemia and perioperative outcomes in patients who underwent cardiac surgery. PATIENTS AND METHODS:We conducted a retrospective observational study of consecutive adult patients who underwent cardiac surgery between June 10, 2002, and Augu...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/80.7.862

    authors: Gandhi GY,Nuttall GA,Abel MD,Mullany CJ,Schaff HV,Williams BA,Schrader LM,Rizza RA,McMahon MM

    更新日期:2005-07-01 00:00:00

  • Effect on hemoglobin A1 of rapid normalization of glycemia with an artificial endocrine pancreas.

    abstract::Six insulin-requiring chronically hyperglycemic diabetic patients underwent glucose control for 72 hours with an artificial endocrine pancreas, the Biostator Glucose Controller. Euglycemia was within 4 hours and was maintained (110 leads to 2 mg/dl) thereafter. The concentration of hemoglobin A (HbA) was elevated, at ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Service FJ,Fairbanks VF,Rizza RA

    更新日期:1981-06-01 00:00:00

  • Tubulomembranous lesions in p-bromophenylacetylurea neuropathy reflect local stasis of fast axonal transport: evidence from electron microscopic autoradiography.

    abstract::The source of the membranous materials that accumulate in distal axons of rats intoxicated with p-bromophenylacetylurea (BPAU) was studied by electron microscopy. 35S-Methionine was injected into the ventral horn of the spinal cord at 2, 14, and 35 days after injection of BPAU. Three days later, samples of the deep pe...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/s0025-6196(12)61550-x

    authors: Oka N,Brimijoin WS

    更新日期:1992-04-01 00:00:00

  • Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging.

    abstract::A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise, may attenuate cognitive impairment and reduce dementia risk. We used PubMed (keywords exercise and cognition) and manuscript bibliographies to examine the published evidence of a cognitive neuroprotective effect of exercise. M...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/mcp.2011.0252

    authors: Ahlskog JE,Geda YE,Graff-Radford NR,Petersen RC

    更新日期:2011-09-01 00:00:00

  • An unusual compressive syndrome of the cauda equina.

    abstract::An unusual case of a capillary hemangioma of the filum terminale is presented. The successful removal returned the patient to an asymptomatic state. ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Freeman RE,Onofrio BM,Layton DD Jr

    更新日期:1975-03-01 00:00:00

  • Prognostic Significance of Holter Monitor Findings in Patients With Light Chain Amyloidosis.

    abstract:OBJECTIVE:To evaluate the prognostic impact of Holter findings in patients with light chain amyloidosis. PATIENTS AND METHODS:We evaluated 239 patients in whom light chain amyloidosis was diagnosed from January 1, 2010, through December 31, 2015, who underwent 24-hour Holter monitoring. RESULTS:Holter testing was don...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2018.08.039

    authors: Sidana S,Tandon N,Brady PA,Grogan M,Gertz MA,Dispenzieri A,Lin G,Dingli D,Buadi FK,Lacy MQ,Kapoor P,Gonsalves WI,Muchtar E,Warsame R,Kumar SK,Kourelis TV

    更新日期:2019-03-01 00:00:00

  • Unusual recovery from acute panautonomic neuropathy after immunoglobulin therapy.

    abstract::A 33-year-old woman with acute idiopathic postganglionic panautonomic neuropathy experienced prompt recovery of all dysautonomic symptoms after receiving high-dose intravenous immunoglobulin therapy. Her recovery was complete within 6 months after onset of disease. This unusually rapid and complete recovery in compari...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.4065/72.4.333

    authors: Smit AA,Vermeulen M,Koelman JH,Wieling W

    更新日期:1997-04-01 00:00:00

  • Frequency and Appropriateness of Fasting Orders in the Hospital.

    abstract:OBJECTIVE:To evaluate the frequency and appropriateness of nil per os (nothing by mouth) (NPO) orders and determine the number of meals missed because of these orders among hospitalized patients. PATIENTS AND METHODS:We retrospectively analyzed inpatient NPO orders at an academic institution in the United States. The ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2015.07.013

    authors: Sorita A,Thongprayoon C,Ahmed A,Bates RE,Ratelle JT,Rieck KM,Devalapalli AP,Issa M,Shah RM,Lalama MA,Wang Z,Murad MH,Kashiwagi DT

    更新日期:2015-09-01 00:00:00

  • Alternative Splicing of G Protein-Coupled Receptors: Relevance to Pain Management.

    abstract::Drugs that target G protein-coupled receptors (GPCRs) represent the primary treatment strategy for patients with acute and chronic pain; however, there is substantial individual variability in both the efficacy and adverse effects associated with these drugs. Variability in drug responses is due, in part, to individua...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/j.mayocp.2015.06.010

    authors: Oladosu FA,Maixner W,Nackley AG

    更新日期:2015-08-01 00:00:00

  • Coronary revascularization on balance: Robert L. Frye lecture.

    abstract::The first generation of multicenter randomized controlled trials of coronary artery bypass surgery vs medical treatment in the 1970s found survival advantage only in patients with left main coronary artery disease or with multiple risk factors. Over time, these results have remained reproducible and biologically plaus...

    journal_title:Mayo Clinic proceedings

    pub_type:

    doi:10.4065/77.1.72

    authors: Detre KM,Holubkov R

    更新日期:2002-01-01 00:00:00

  • Use of Echocardiography in Olmsted County Outpatients With Chest Pain and Normal Resting Electrocardiograms Seen at Mayo Clinic Rochester.

    abstract:OBJECTIVE:To determine how often unnecessary resting echocardiograms that are "not recommended" by clinical practice guidelines are performed in patients with stable chest pain and normal resting electrocardiograms (ECGs). PATIENTS AND METHODS:We performed a retrospective search of electronic medical records of all ou...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2015.07.025

    authors: Gibbons RJ,Carryer D,Liu H,Brady PA,Askew JW,Hodge D,Ammash N,Ebbert JO,Roger VL

    更新日期:2015-11-01 00:00:00

  • Q fever: epidemiology, diagnosis, and treatment.

    abstract::Q fever, a zoonosis caused by Coxiella burnetii, is seen throughout the world. Recent reports suggest that its incidence in the United States is increasing, with more than 30 cases reported in the US military. The disease has many acute and chronic manifestations. Endocarditis is the most common form of chronic diseas...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.4065/83.5.574

    authors: Hartzell JD,Wood-Morris RN,Martinez LJ,Trotta RF

    更新日期:2008-05-01 00:00:00

  • Ultrastructural studies of platelets of von Willebrand and normal swine.

    abstract::Platelets from normal pigs and pigs with von Willebrand's disease were studied by ultrastructural and scanning electron microscopy. The majority of resting platelets were discoid or abortive-dendritic in gross morphology with an average size of 2.6 micrometer. The number of alpha-granules per platelet section was vari...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Lewis JC,Bowie FJ

    更新日期:1978-03-01 00:00:00

  • Chronic noncancer pain rehabilitation with opioid withdrawal: comparison of treatment outcomes based on opioid use status at admission.

    abstract:OBJECTIVE:To study differences in treatment outcomes between patients with chronic noncancer pain taking vs those not taking maintenance opioids at admission to a pain rehabilitation program. PATIENTS AND METHODS:A nonrandomized 2-group prepost design was used to compare 356 patients admitted to the Mayo Comprehensive...

    journal_title:Mayo Clinic proceedings

    pub_type: 临床试验,杂志文章

    doi:10.4065/79.6.759

    authors: Rome JD,Townsend CO,Bruce BK,Sletten CD,Luedtke CA,Hodgson JE

    更新日期:2004-06-01 00:00:00

  • Computed tomography of the large bowel and appendix.

    abstract::Computed tomography (CT) of the colon is useful in assessment of patients with colonic disease because the entire bowel wall, extraluminal tissues, and adjacent solid organs can be directly visualized. Patients with advanced stage colorectal carcinoma can be reliably identified with CT. This information can assist in ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审

    doi:10.1016/s0025-6196(12)61291-9

    authors: Johnson CD,Stephens DH

    更新日期:1989-10-01 00:00:00

  • Dos Quatro by Bill Barrett.

    abstract::Recognizing the contribution art has had in the Mayo Clinic environment since the original Mayo Clinic Building was finished in 1914, Mayo Clinic Proceedings features some of the numerous works of art displayed throughout the buildings and grounds on Mayo Clinic campuses as interpreted by the author. ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2017.07.004

    authors: Wentz MR

    更新日期:2017-09-01 00:00:00

  • Pertussis outbreak, southeastern Minnesota, 2012.

    abstract:OBJECTIVE:To describe clinical and laboratory findings from the 2012 southeastern Minnesota pertussis outbreak. PATIENTS AND METHODS:Patients were selected for 2 parts of the study. In the first part, nasopharyngeal swabs from a convenience sample of 265 unique patients were used for both the clinician-requested polym...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2014.08.004

    authors: Theofiles AG,Cunningham SA,Chia N,Jeraldo PR,Quest DJ,Mandrekar JN,Patel R

    更新日期:2014-10-01 00:00:00

  • Effect of Preprocedural Thrombocytopenia on Prognosis After Percutaneous Coronary Intervention.

    abstract:OBJECTIVE:To assess early and late outcomes, including bleeding, in patients with thrombocytopenia undergoing percutaneous coronary intervention (PCI). PATIENTS AND METHODS:We performed a retrospective single-center study of patients with preprocedural thrombocytopenia (platelet count ≤100,000/μL; n=204) undergoing PC...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:10.1016/j.mayocp.2016.05.008

    authors: Raphael CE,Spoon DB,Bell MR,Psaltis PJ,Kidd S,Loh SX,Lennon RJ,Singh M,Rihal C,Gulati R

    更新日期:2016-08-01 00:00:00

  • Infective endocarditis caused by Actinobacillus actinomycetemcomitans: report of four cases.

    abstract::Four patients with infective endocarditis caused by Actinobacillus actinomycetemcomitans are reported. The clinical course was characterized by chronicity. Three of the four patients were treated with combined penicillin and aminoglycoside therapy on an empiric basis; the fourth patient was given ampicillin alone for ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章

    doi:

    authors: Geraci JE,Wilson WR,Washington JA 2nd

    更新日期:1980-07-01 00:00:00