An unusual compressive syndrome of the cauda equina.

abstract：:The Human Genome Project has resulted in a new era in the field of pharmacogenetics in which researchers are rapidly discovering new genetic variation, which may help to explain interindividual variability in drug efficacy and toxicity. Pharmacogenetics is the study of the role of genetic inheritance in individual var...

journal_title：Mayo Clinic proceedings

authors： Goetz MP,Ames MM,Weinshilboum RM

更新日期：2004-03-01 00:00:00

abstract：:Total joint replacement in the upper extremity has developed in step with that of the lower extremity. The indications for treatment, the place of total joint arthroplasty in contrast to other forms of arthroplasty, and the criteria for patient selection have recently been classified. A number of problem areas are und...

journal_title：Mayo Clinic proceedings

authors： Cooney WP 3rd

更新日期：1979-08-01 00:00:00

abstract：:The recent Mayo Clinic experience in the diagnosis and treatment of infectious diseases in Indochinese refugees is discussed. One hundred patients from whom stool and blood specimens were submitted for parasitic examination showed a high percentage of parasitic infection, often with multiple agents. An outline for the...

journal_title：Mayo Clinic proceedings

authors： Jones MJ,Thompson JH Jr,Brewer NS

更新日期：1980-08-01 00:00:00

abstract：:Hypothyroidism and hyperthyroidism are common medical disorders that are often accompanied by diverse types of neurologic and neuromuscular dysfunction. Although some of these associated disorders are well known to physicians, others are not. All of these neurologic manifestations are important because they can severe...

journal_title：Mayo Clinic proceedings

authors： Swanson JW,Kelly JJ Jr,McConahey WM

更新日期：1981-08-01 00:00:00

abstract：:Lipoproteins are known to be able to transport a variety of drugs. This report suggests that low-density lipoprotein not only functions as an important carrier of cyclosporine in plasma but also facilitates transport of cyclosporine across the cell membrane by means of the low-density lipoprotein receptor. Such a mech...

journal_title：Mayo Clinic proceedings

authors： de Groen PC

更新日期：1988-10-01 00:00:00

abstract：:The metabolic syndrome is an insulin-resistant state characterized by a cluster of cardiovascular risk factors, including various combinations of abdominal obesity, glucose intolerance, hypertension, and atherogenic dyslipidemia (elevated triglyceride values, low high-density lipoprotein cholesterol levels, and small ...

journal_title：Mayo Clinic proceedings

authors： Johnson LW,Weinstock RS

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To investigate a recent association between the use of the angiotensin receptor-blocker (ARB) olmesartan and a severe enteropathy resembling celiac disease. PATIENTS AND METHODS:We searched our endoscopy database for all outpatient esophagogastroduodenoscopy (EGD) or colonoscopy examinations in patients aged...

journal_title：Mayo Clinic proceedings

authors： Greywoode R,Braunstein ED,Arguelles-Grande C,Green PH,Lebwohl B

更新日期：2014-09-01 00:00:00

abstract：:After the completion of the Human Genome Project, there has been an acceleration in methodologies on sequencing nucleic acids (DNA and RNA) at a high precision and with ever-decreasing turnaround time and cost. Collectively, these approaches are termed next-generation sequencing and are already affecting the transform...

journal_title：Mayo Clinic proceedings

authors： Stephens MC,Boardman LA,Lazaridis KN

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy of laparoscopy in the diagnosis of intra-abdominal lymphoma. PATIENTS AND METHODS:The medical records of patients with suspected primary or recurrent lymphoma who underwent laparoscopy between March 1991 and March 2003 were reviewed. Demographic, clinical, operative, and pathologic dat...

journal_title：Mayo Clinic proceedings

authors： Asoglu O,Porter L,Donohue JH,Cha SS

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The efficacy of fine-needle aspiration (FNA) biopsy and its role in the management of a nodular goiter are clearly established. The accuracy of cytologic diagnosis approaches 95%. FINDINGS:FNA biopsy is a reasonable approach to thyroid nodules; it has decreased costs substantially because it facilitates sel...

journal_title：Mayo Clinic proceedings

authors： Gharib H

更新日期：1994-01-01 00:00:00

abstract：:Eighty-two consecutive orthopedic patients were assessed nutritionally at the time of hospital admission and then at 10-day intervals until hospital dismissal. Forty-eight percent of the patients had one or more abnormal findings suggestive of protein-calorie malnutrition. In spite of this prevalence of abnormal findi...

journal_title：Mayo Clinic proceedings

authors： Dreblow DM,Anderson CF,Moxness K

更新日期：1981-01-01 00:00:00

abstract：FINDINGS:The prostate-specific antigen (PSA) level alone does not facilitate precise pathologic staging on an individual basis, although advanced stage tends to correlate with an increased PSA level. The staging accuracy of PSA, however, can be enhanced by considering the variables of tumor grade and clinical stage. St...

journal_title：Mayo Clinic proceedings

authors： Ruckle HC,Klee GG,Oesterling JE

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of the sequence of treatment with rituximab and/or splenectomy on time to relapse for patients with steroid-refractory immune thrombocytopenia (ITP). PATIENTS AND METHODS:Patients 18 years or older with steroid-refractory immune thrombocytopenia who underwent treatment with splenectomy...

journal_title：Mayo Clinic proceedings

authors： Hammond WA,Vishnu P,Rodriguez EM,Li Z,Dholaria B,Shreders AJ,Rivera CE

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To estimate cancer risks for patients with myotonic dystrophy, given that increased risks for neoplasms in association with myotonic dystrophy type 1 and type 2 have been suggested in several studies but the risks of cancers have not been quantified. PATIENTS AND METHODS:A cohort of 307 patients with myotoni...

journal_title：Mayo Clinic proceedings

authors： Win AK,Perattur PG,Pulido JS,Pulido CM,Lindor NM

更新日期：2012-02-01 00:00:00

abstract：:In 51 patients, the cause for pleural effusion remained indeterminate immediately after thoracotomy. Thirty-one (60.8%) had no recurrence of the effusion, and no cause became apparent during a follow-up period of from 1 1/2 to 15 years. Two patients (3.9%) died relatively soon after thoracotomy, but death was not clea...

journal_title：Mayo Clinic proceedings

authors： Ryan CJ,Rodgers RF,Unni KK,Hepper NG

更新日期：1981-03-01 00:00:00

abstract：:Stereotactic ventralis lateralis thalamotomy can be performed in selected patients with medically intractable parkinsonian tremor and rigidity. New technology, including computed tomography-based stereotaxis and microelectrode recording techniques, provides a data base for precise localization of thalamic lesions tail...

journal_title：Mayo Clinic proceedings

authors： Kelly PJ,Ahlskog JE,Goerss SJ,Daube JR,Duffy JR,Kall BA

更新日期：1987-08-01 00:00:00

abstract：:Coronary artery fistulas are infrequently encountered vascular communications that are either congenital or due to cardiac trauma. Most patients with these anomalies are asymptomatic, but late complications can occur and include congestive heart failure, myocardial ischemia, arrhythmias, and endocarditis. Therefore, m...

journal_title：Mayo Clinic proceedings

authors： Harris WO,Andrews JC,Nichols DA,Holmes DR Jr

更新日期：1996-01-01 00:00:00

abstract：:Evidence suggests that migraine is associated with decreased productivity. This article describes the results of a systematic literature review of peer-reviewed publications that measured the impact of migraine on workplace productivity in the United States and provides recommendations for future research. A MEDLINE s...

journal_title：Mayo Clinic proceedings

authors： Burton WN,Landy SH,Downs KE,Runken MC

更新日期：2009-05-01 00:00:00

abstract：:Many types of psychotherapeutic drugs (especially antidepressants) directly and indirectly interact with neurotransmitter receptors, the recognition sites for the chemical messengers released by neurons. These interactions can result in increased or decreased sensitivity of certain receptors. Hypotheses exist to expla...

journal_title：Mayo Clinic proceedings

authors： Richelson E,El-Fakahany E

更新日期：1982-09-01 00:00:00

abstract：:Among 169 adult pathologically staged patients with Hodgkin's disease who were treated at the Mayo Clinic between 1974 and 1978, we identified four cases of second malignant lesions that developed. The median duration of follow-up after diagnosis for the entire population was 4.1 years. Of the 169 patients, 73 receive...

journal_title：Mayo Clinic proceedings

authors： Schomberg PJ,Evans RG,Banks PM,White WL,O'Connell MJ,Earle JD

更新日期：1984-07-01 00:00:00

abstract：:The symptoms of progressive dyspnea, hemoptysis, spontaneous pneumothorax, chylous effusions, and cough in conjunction with ventilatory obstruction and abnormal gas exchange in a young woman should prompt the diagnosis of pulmonary lymphangiomyomatosis. Cytosol steroid-receptor assays and postmortem studies were condu...

journal_title：Mayo Clinic proceedings

authors： Graham ML 2nd,Spelsberg TC,Dines DE,Payne WS,Bjornsson J,Lie JT

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the frequency and pattern of complementary and alternative medicine (CAM) use in patients referred to a fibromyalgia treatment program at a tertiary care center. PATIENTS AND METHODS:Patients referred to the Mayo Fibromyalgia Treatment Program between February 2003 and July 2003 were invited on t...

journal_title：Mayo Clinic proceedings

authors： Wahner-Roedler DL,Elkin PL,Vincent A,Thompson JM,Oh TH,Loehrer LL,Mandrekar JN,Bauer BA

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and tolerability of sumatriptan, 50-mg and 100-mg tablets, compared with placebo for treatment of migraine at the first sign of pain. PATIENTS AND METHODS:Two identical multicenter randomized, double-blind, placebo-controlled, single-attack studies were conducted from May through Nov...

journal_title：Mayo Clinic proceedings

authors： Winner P,Mannix LK,Putnam DG,McNeal S,Kwong J,O'Quinn S,Richardson MS

更新日期：2003-10-01 00:00:00

abstract：:In a group of 47 patients with mediastinal granulomas, the most common clinical symptoms were cough, chest pain, dysphagia, hemoptysis, and dyspnea. The main laboratory findings were right paratracheal or hilar mass on chest roentgenogram, positive histoplasmin skin test, and caseating granuloma on histopathologic exa...

journal_title：Mayo Clinic proceedings

authors： Strimlan CV,Dines DE,Payne WS

更新日期：1975-12-01 00:00:00

abstract：:Two patients had both scleroderma and a columnar epithelium-lined lower esophagus (Barrett esophagus). Features of Barrett's esophagus included high esophageal strictures in both patients and ulcer craters in the columnar area of one. Biopsy confirmed columnar epithelium in the lower esophagus of each patient. In thes...

journal_title：Mayo Clinic proceedings

authors： Cameron AJ,Payne WS

更新日期：1978-09-01 00:00:00

abstract：:Eleven patients with Alport's syndrome had renal transplantation between 1963 and 1980. The mean follow-up is 6 years (6 months to 14 years). All 11 patients are currently alive. Ten have functioning grafts, and in nine the serum creatinine concentration is less than 2 mg/dl. Three patients received a second allograft...

journal_title：Mayo Clinic proceedings

authors： Milliner DS,Pierides AM,Holley KE

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:To describe current concepts in the diagnosis and treatment of brain metastases. RESULTS:More than 25% of all autopsy-proven brain metastases have a pulmonary source. Most brain metastases manifest with a combination of focal and generalized symptoms and signs. Typically, patients have subacute, progressive ...

journal_title：Mayo Clinic proceedings

authors： O'Neill BP,Buckner JC,Coffey RJ,Dinapoli RP,Shaw EG

更新日期：1994-11-01 00:00:00

abstract：:Primary sclerosing cholangitis (PSC) predisposes to the development of cholangiocarcinoma, a usually fatal complication that is difficult to diagnose. Serum concentrations of CA 19-9, a tumor-associated antigen, are frequently increased in patients with only cholangiocarcinoma. The aim of this study was to assess the ...

journal_title：Mayo Clinic proceedings

authors： Nichols JC,Gores GJ,LaRusso NF,Wiesner RH,Nagorney DM,Ritts RE Jr

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of fetal urinary tract anomalies and to characterize the types of such abnormalities detected on ultrasonography and the outcome of affected patients during a 15-year period at our institution. DESIGN:We retrospectively reviewed the findings on maternal prenatal ultrasound examinat...

journal_title：Mayo Clinic proceedings

authors： Gloor JM,Ogburn PL Jr,Breckle RJ,Morgenstern BZ,Milliner DS

更新日期：1995-06-01 00:00:00

abstract：:Noninvasive ventilation refers to the delivery of assisted ventilatory support without the use of an endotracheal tube. Noninvasive positive pressure ventilation (NPPV) can be delivered by using a volume-controlled ventilator, a pressure-controlled ventilator, a bilevel positive airway pressure ventilator, or a contin...

journal_title：Mayo Clinic proceedings

authors： Rabatin JT,Gay PC

更新日期：1999-08-01 00:00:00