Abstract:
:Susac syndrome is an occlusive arteriolar disease that provokes infarcts in the cochlea, retina, and brain of young subjects, mostly women. Its cause is unknown. Some infarcts may be asymptomatic and only revealed by ancillary investigation: 1) audiogram that shows bilateral sensorineural hearing loss predominating on low frequencies, 2) funduscopy and fluorescein retinal angiography demonstrating bilateral distal branch retinal artery occlusions, and 3) brain MRI T2-weighted images disclosing small multifocal hyperintensities in white and gray matter. Treatment options are not codified, ranging from antithrombotic drugs to immunomodulatory therapy. Course is self-limited after an active fluctuating phase. Dementia, blindness, and deafness are rare late sequelae, and half of patients return to normal life.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Papo T,Biousse V,Lehoang P,Fardeau C,N'Guyen N,Huong DL,Aumaitre O,Bousser MG,Godeau P,Piette JCdoi
10.1097/00005792-199801000-00002subject
Has Abstractpub_date
1998-01-01 00:00:00pages
3-11issue
1eissn
0025-7974issn
1536-5964journal_volume
77pub_type
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