Triglyceride to HDL-cholesterol ratio as an independent risk factor for the poor development of coronary collateral circulation in elderly patients with ST-segment elevation myocardial infarction and acute total occlusion.


:To determine the prognostic role of triglyceride (TG) to high-density lipoprotein cholesterol (HDL) ratio for poorly developed coronary collateral circulation (CCC) in elderly patients with ST-segment elevation myocardial infarction (STEMI) and acute total occlusion (ATO).As a retrospective case-control study, elderly patients (age ≥60 years) with both STEMI and ATO (n = 346) were classified as having either poorly- or well-developed CCC (Rentrop grades 0-1 and 2-3, respectively). The ratio of TG/HDL was calculated according to the detected levels of TG and HDL. The difference of TG/HDL ratio in those 2 groups was compared by Student t test, and multivariate logistic regression analysis indicating occurrence of poorly developed CCC was performed. Receiver operator characteristic curve (ROC) analysis of TG/HDL ratio which determine the optimal cut-off value of TG/HDL ratio was applied.The TG/HDL ratio was significantly higher in patients with poorly developed CCC than in those with well-developed CCC (2.88 ± 2.52 vs 1.81 ± 1.18, P < .001). In multivariate logistic regression analysis, higher TG/HDL ratio (OR 1.789, 95% CI 1 . 346-2.378, P < .001) and the presence of left circumflex branch of coronary artery (LCX) occlusion (OR6.235, 95% CI 2.220-17.510, P = .001) were emerged as independent positive predictors of poor development of CCC, whereas presence of right coronary artery (RCA) occlusion (OR 0.474, 95% CI 0.265-0.850, P = .002) and onset time (OR 0.693, 95% CI 0.620-0.775, P < .001) were found as negative indicators. The optimal cut-off value of TG/HDL ratio was found as 1.58 in ROC analysis, which yielded an area under the curve value of 0.716 (95% CI 0.654-0.778, P < .001) and demonstrated a sensitivity of 80.9% and a specificity of 59.3% for prediction of poorly developed CCC.TG/HDL ratio is an independent risk factor for predicting poor development of CCC in elderly patients with STEMI and ATO.


Medicine (Baltimore)




Liu GY,Meng XX,Zhang Z




Has Abstract


2018-09-01 00:00:00
















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    abstract:BACKGROUND:To assess the effect of dexmedetomidine added to ropivaccaine on the onset and duration of sensory block, as well as postoperative analgesia during caudal anesthesia in patients undergoing hemorrhoidectomy. METHODS:Fifty adult patients scheduled for hemorrhoidectomy were divided into 2 groups. The group R r...


    pub_type: 杂志文章,随机对照试验


    authors: Xu D,Xiu M,Zhang X,Zhu P,Tian L,Feng J,Wu Y,Zhao Z,Luan H

    更新日期:2018-08-01 00:00:00

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    abstract::Peritoneal dialysis (PD) is one type of renal replacement therapy, but potential peritoneal damage and gastrointestinal (GI) tract adverse effects during long-term exposure to bio-incompatible dialysate remain a concern. Although GI disease frequently occurs in dialysis patients, whether the risk of GI diseases differ...


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    authors: Lee YC,Hung SY,Wang HH,Wang HK,Lin CW,Chang MY,Ho LC,Chen YT,Wu CF,Chen HC,Wang WM,Sung JM,Chiou YY,Lin SH

    更新日期:2015-09-01 00:00:00

  • Contrast-enhanced ultrasound for evaluation of high-intensity focused ultrasound treatment of benign uterine diseases: retrospective analysis of contrast safety.

    abstract::As a noninvasive treatment technique, ultrasound-guided high-intensity focused ultrasound (HIFU) has been considered as a routine treatment for uterine fibroids and adenomyosis in China. Contrast-enhanced ultrasound (CEUS) has been proposed as another option to assess the treatment efficacy during HIFU treatment. The ...


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    authors: Cheng CQ,Zhang RT,Xiong Y,Chen L,Wang J,Huang GH,Li KQ,Zhang L,Bai J

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    abstract::The present study aimed to explore genetic association of receptor activator nuclear factor κB (RANK) polymorphisms with individual susceptibility to knee osteoarthritis (OA) in different Kellgren-Lawrence (KL) grades.This case-control study included 138 knee OA patients and 145 healthy individuals. RANK rs1805034 and...


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    更新日期:2020-08-14 00:00:00

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    authors: Li J,Wu H,Huang X,Xu D,Zheng W,Zhao Y,Liu W,Zeng X

    更新日期:2014-08-01 00:00:00

  • Aspartate aminotransferase to platelet ratio can reduce the need for transient elastography in Chinese patients with chronic hepatitis B.

    abstract::In the absence of liver biopsy and transient elastography (TE), aspartate aminotransferase to platelet ratio (APRI), fibrosis-4 score (FIB-4), and gammaglutamyl transpeptidase to platelet ratio (GPR) are simple and inexpensive methods for the detection of liver fibrosis. AIMS:We compared the performance of APRI, FIB-...


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    authors: Yue W,Li Y,Geng J,Wang P,Zhang L

    更新日期:2019-12-01 00:00:00

  • Effects of epinephrine for out-of-hospital cardiac arrest: A systematic review and meta-analysis of randomized controlled trials.

    abstract:AIM:Our objective is to assess the effects of epinephrine for out of hospital cardiac arrest. BACKGROUND:Cardiac arrest was the most serious medical incidents with an estimated incidence in the United States of 95.7 per 100,000 person years. Though epinephrine improved coronary and cerebral perfusion, improving a retu...


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    authors: Huan L,Qin F,Wu Y

    更新日期:2019-11-01 00:00:00

  • Group A streptococcal bacteremia. A 10-year prospective study.

    abstract::In this paper we present a prospective evaluation of 100 patients with Group A Streptococcal (GAS) bacteremia evaluated in our hospital over a 10-year period. Sixty-two patients were intravenous drug users (IVDU); all but 1 of these had an obvious cutaneous portal of entry related to the injection of illicit drugs. Tw...


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    authors: Bernaldo de Quirós JC,Moreno S,Cercenado E,Diaz D,Berenguer J,Miralles P,Catalán P,Bouza E

    更新日期:1997-07-01 00:00:00

  • Association of polymorphisms in STRA6 gene with gestational diabetes mellitus in a Chinese Han population.

    abstract::Cell and animal experiments have found that in addition to being a retinol transporter, Stimulated by Retinoic Acid 6 (STRA6) also functions as a surface signaling receptor by which retinol regulates insulin responses. Several studies revealed that the STRA6 gene may contribute to the pathogenesis of type 2 diabetes m...


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    authors: Hu S,Yan J,You Y,Yang G,Zhou H,Li X,Liao X,Tan H

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  • Using a cervical ripening balloon to penetrate the placenta and quickly reduce bleeding by pressing against the placenta during pregnancy termination for patients with placenta previa in the second trimester: Two cases report.

    abstract:INTRODUCTION:The clinical treatment is complicated for patients with placenta previa who must terminate pregnancy due to fetal malformation, death, or inevitable abortion in the second trimester. It is difficult to manage excessive bleeding during pregnancy termination; and those patients face risks of removing the ute...


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    authors: Su C,Chen D

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  • Perioperative and Anesthesia-Related Mortality: An 8-Year Observational Survey From a Tertiary Teaching Hospital.

    abstract::In 2006, a previous study at our institution reported high perioperative and anesthesia-related mortality rates of 21.97 and 1.12 per 10,000 anesthetics, respectively. Since then, changes in surgical practices may have decreased these rates. However, the actual perioperative and anesthesia-related mortality rates in B...


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    authors: Pignaton W,Braz JRC,Kusano PS,Módolo MP,de Carvalho LR,Braz MG,Braz LG

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    pub_type: 临床试验,杂志文章


    authors: Johnson JP,Moore J Jr,Austin HA 3rd,Balow JE,Antonovych TT,Wilson CB

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    authors: Hsu CC,Hsu YC,Chen HJ,Lin CC,Chang KH,Lee CY,Chong LW,Kao CH

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    abstract::This prospective study investigated the relationship between 2 inosine triphosphatase (ITPA) polymorphisms (rs7270101 and rs1127354) and the efficacy of ribavirin-based antiviral therapy in hepatitis C virus (HCV)-infected Chinese patients.A total of 906 patients diagnosed with chronic hepatitis C receiving pegylated ...


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    authors: Liu Z,Wang S,Qi W,Wang X,Sun D,Wang H,Zhang Y,Li Z,Zhu L,Zhao P,Guo H,Zhou C,Wang J

    更新日期:2017-07-01 00:00:00

  • Treat the congenital pseudarthrosis of the Tibia with Ilizarov technology: Case report.

    abstract:RATIONALE:According to previously published studies, treating pediatric patients with congenital pseudarthrosis of the tibia (CPT) is challenging. More effective methods are needed to treat this patient population. PATIENT CONCERNS:A 7-year-old girl with congenital pseudarthrosis of the distal tibia, previously misdia...


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  • A meta-analytic review of prevalence for Brugada ECG patterns and the risk for death.

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    authors: Xie H,Xue L,Hua W,Jia B,Zhang L,Li L

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    authors: Özdemir G

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    pub_type: 杂志文章


    authors: Lu ZH,Kang XQ

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    pub_type: 杂志文章


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