Abstract:
:Paired maternal/cord blood samples were tested for anti-Toxoplasma IgG or IgM antibodies using Biomerieux Micro-EIA2 IgG and IgM test kits. Of the 1503 women tested at the time of delivery, 344 (22.9%) were IgG seropositive. Three hundred and one maternal sera, including 265 that were IgG positive, were tested for IgM antibodies: 47 were found positive, indicating a gestational toxoplasmosis incidence of 31 per 1000 pregnancies over one year. All but one of the IgM positive maternal sera had tested IgG positive. Cord blood IgG seropositivity was similar to the maternal rate but 18 of the 301 babies had significant levels of anti-Toxoplasma IgM antibodies. As these 18 babies were all born to mothers also positive for IgM antibodies, the calculated rate of transplacental transmission was 38.3% with the estimated prevalence of congenital toxoplasmosis of 12 per 1000 live births. There was no statistically significant positive correlation between maternal seroprevalence and such well-known risk factors as consumption of raw meat and milk, or proximity of cats and other animals. One baby was born with the classical stigmata of congenital toxoplasmosis.
journal_name
Eur J Epidemioljournal_title
European journal of epidemiologyauthors
Dar FK,Alkarmi T,Uduman S,Abdulrazzaq Y,Grundsell H,Hughes Pdoi
10.1023/a:1007392703037subject
Has Abstractpub_date
1997-07-01 00:00:00pages
567-71issue
5eissn
0393-2990issn
1573-7284journal_volume
13pub_type
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journal_title:European journal of epidemiology
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journal_title:European journal of epidemiology
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