Abstract：
:The cells of the fundic portion of canine gastric mucosa were dispersed by collagenase digestion and separated into fractions by sequential use of velocity sedimentation in an elutriator rotor followed by a density gradient separation. There was a close correlation between histamine content and number of mast cells in the different cell fractions. The mast cells possessed characteristic dense granules, which stained metachromatically, but did not release histamine on exposure to Compound 48/80. The most highly purified fractions contained 80% mast cells and a histamine content of 2.5 pg/mast cell.
journal_name
Gastroenterologyjournal_title
Gastroenterologyauthors
Soll AH,Lewin K,Beaven MAsubject
Has Abstractpub_date
1979-12-01 00:00:00pages
1283-90issue
6eissn
0016-5085issn
1528-0012pii
S0016508579002377journal_volume
77pub_type
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