Abstract:
:The distribution and identity of the various endocrine cell types were examined in the pancreas, stomach, and anterior intestine of the phylogenetically ancient actinopterygian, the gar (Lepisosteus osseus L.), using immunohistochemistry. Antisera used were directed against several insulins (INSs) and somatostatins (SSTs), and members of the pancreatic polypeptide (PP, aPY, NPY) and glucagon (GLUC, GLP) families. In the gar pancreas the most pronounced aggregation of islet tissue is among the exocrine acini near the union of extrahepatic common bile duct with the gastrointestinal junction. Four immunoreactive cell types were identified within well-defined islets (A, B, D, and F cells) but immunoreactive cell types were also seen isolated among the exocrine acini. Centrally located B cells were immunoreactive with mammalian and lamprey INS antisera whereas the widely dispersed D cells immunostained with anti-SST-14, -25, and -34. SST was also localized in the epithelium of the pancreatic ducts. There was a colocalization of immunoreactivity for each member of the PP and GLU families at the periphery of each islet to identify F and A cells, respectively. However, colocalization of peptides from both families is suspected for at least some cells. Although the gastric and intestinal mucosae showed a similar pattern of immunoreactivity to GLP and not GLU, they had contrasting immunoreactivity with the two INS antisera. SST immunoreactivity was restricted to the stomach, whereas three of the four PP-family peptides were only immunoreactive in the intestine. Immunoreactivity to the various antisera used in the study imply that there may be an organ-specific processing of preproinsulin, that the gar SST profile may be more similar to agnathan and bowfin rather than either elasmobranch or teleost SSTs, and that only the GLP portion of the preproglucagon gene is expressed in the gastrointestinal mucosa. Our results are consistent with other recent endocrine studies showing that the gar is a widely distinct actinopterygian.
journal_name
Gen Comp Endocrinoljournal_title
General and comparative endocrinologyauthors
Groff KE,Youson JHdoi
10.1006/gcen.1996.6842subject
Has Abstractpub_date
1997-04-01 00:00:00pages
1-16issue
1eissn
0016-6480issn
1095-6840pii
S0016-6480(96)96842-2journal_volume
106pub_type
杂志文章abstract::Steroid hormones play an important role in modulating behavioral responses to various social stimuli. It has been suggested that variation in the hormonal regulation of behavior across species is associated with social organization and/or mating system. In order to further elucidate the interplay of hormones and behav...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2013.04.031
更新日期:2013-08-01 00:00:00
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journal_title:General and comparative endocrinology
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
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更新日期:2018-07-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1999.7438
更新日期:2000-06-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2014.08.008
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1994.1143
更新日期:1994-09-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1999.7399
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1994.1110
更新日期:1994-07-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1998.7172
更新日期:1998-11-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2012.02.017
更新日期:2012-05-15 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(91)90301-l
更新日期:1991-04-01 00:00:00
abstract::Three species of fish that are phylogenetically older than other members of the bony fish lineage were selected to determine if gonadotropin-releasing hormone (GnRH) is present in their brains. Brain extracts were prepared from each species and found to contain immunoreactive (ir) GnRH. To further characterize the mol...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(91)90063-c
更新日期:1991-10-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2004.03.009
更新日期:2004-07-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2010.10.009
更新日期:2011-01-15 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/s0016-6480(03)00240-5
更新日期:2003-11-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1996.0067
更新日期:1996-05-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
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更新日期:2002-01-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
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更新日期:1985-09-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2008.12.015
更新日期:2009-04-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
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更新日期:2017-05-01 00:00:00
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journal_title:General and comparative endocrinology
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(92)90068-u
更新日期:1992-06-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
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更新日期:2014-04-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
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