Effects of ammonium ions on the depolarization-induced and direct activation of the contractile apparatus in mechanically skinned fast-twitch skeletal muscle fibres of the rat.

abstract：:Because complex structural differences in adult extraocular muscles may have physiological and pathophysiological significance, the three-dimensional pattern of myosin heavy chain (MHC) isoform expression within the orbital and global layers of the muscle bellies compared with the distal tendon ends was quantitatively...

journal_title：Journal of muscle research and cell motility

authors： McLoon LK,Rios L,Wirtschafter JD

更新日期：1999-11-01 00:00:00

abstract：:Filamin binds to F-actin and influences the myosin-actin interaction. At relatively low concentrations, filamin activates actomyosin Mg2+-ATPase, whereas higher concentrations of filamin exert an inhibitory effect. Activation of ATPase activity occurs under conditions where a loose meshwork of actin filaments is prese...

journal_title：Journal of muscle research and cell motility

authors： Dabrowska R,Goch A,Osińska H,Szpacenko A,Sosinski J

更新日期：1985-02-01 00:00:00

abstract：:The fine structure of leech body wall muscles, has been analysed under great length variations. All the measurable parameters of the fibre (distance between thick filaments, sarcomere and A band width, percentage of actin crowns around myosin filaments, fibre radius) at different elongations were tested with equations...

journal_title：Journal of muscle research and cell motility

authors： Lanzavecchia G,de Eguileor M,Valvassori R

更新日期：1985-10-01 00:00:00

abstract：:The effect of changes in hydrostatic pressure (up to 10 MPa) on the maximally calcium-activated tension in glycerinated rabbit psoas fibres has been examined. The steady active tension was depressed by 0.8% per MPa pressure rise. This pressure sensitivity was enhanced by the pressure of millimolar phosphate and depres...

journal_title：Journal of muscle research and cell motility

authors： Fortune NS,Geeves MA,Ranatunga KW

更新日期：1989-04-01 00:00:00

abstract：:This paper studies human gallbladder (GB) smooth muscle contractions. A two-state cross-bridge model was used to estimate the apparent attachment and detachment rate constants, as well as increased Ca2+ concentration from the peak active stress during the isometric contraction. The active stress was computed from a me...

journal_title：Journal of muscle research and cell motility

authors： Li WG,Luo XY,Hill NA,Ogden RW,Tian TH,Smythe A,Majeed AW,Bird N

更新日期：2011-11-01 00:00:00

abstract：:Nebulin is an integral protein of skeletal muscle thin filaments and probably acts as a ruler for the thin filament length. Cardiac muscles of higher vertebrates have been shown earlier to lack nebulin. Instead in human and chicken cardiac muscle the much smaller protein nebulette replaces nebulin. Since nebulette is ...

journal_title：Journal of muscle research and cell motility

authors： Fock U,Hinssen H

更新日期：2002-01-01 00:00:00

abstract：:The cellular function of the giant protein titin in striated muscle is a major focus of scientific attention. Particularly, its role in passive mechanics has been extensively investigated. In strong contrast, the structural details of this filament are very poorly understood. To date, only a handful of atomic models f...

journal_title：Journal of muscle research and cell motility

authors： Marino M,Svergun DI,Kreplak L,Konarev PV,Maco B,Labeit D,Mayans O

更新日期：2005-01-01 00:00:00

abstract：:Skeletal muscle has a remarkable ability to respond to different physical stresses. Loading muscle through exercise, either anaerobic or aerobic, can lead to increases in muscle size and function while, conversely, the absence of muscle loading stimulates rapid decreases in size and function. A principal mediator of t...

journal_title：Journal of muscle research and cell motility

authors： Graham ZA,Gallagher PM,Cardozo CP

更新日期：2015-10-01 00:00:00

abstract：:Critical illness myopathy (CIM) is associated with severe muscle atrophy and fatigue in affected patients. Apoptotic signaling is involved in atrophy and is elevated in muscles from patients with CIM. In this study we investigated underlying mechanisms of apoptosis-related pathways in muscles with different fiber type...

journal_title：Journal of muscle research and cell motility

authors： Barnes BT,Confides AL,Rich MM,Dupont-Versteegden EE

更新日期：2015-06-01 00:00:00

abstract：:The effect of urocortin (Uro), a recently discovered neuropeptide with selectivity towards corticotropin-releasing hormone type 2 receptor, was tested on whole cell currents expressed by guinea-pig gastric antrum smooth muscle cells. Uro (1 pmol/l-1 nmol/l) caused a concentration-dependent increase of Ca2+-sensitive K...

journal_title：Journal of muscle research and cell motility

authors： Petkova-Kirova PS,Gagov HS,Duridanova DB

更新日期：2000-01-01 00:00:00

abstract：:Skeletal muscle hypertrophy is a result of increased load, such as functional and stretch-overload. Activation of satellite cells and proliferation, differentiation and fusion are required for hypertrophy of overloaded skeletal muscles. On the contrary, a dramatic loss of skeletal muscle mass determines atrophy settin...

journal_title：Journal of muscle research and cell motility

authors： Cassano M,Quattrocelli M,Crippa S,Perini I,Ronzoni F,Sampaolesi M

更新日期：2009-12-01 00:00:00

abstract：:The pattern of expression of different types of myosin heavy chains and the development of different generations of muscle cells during foetal life were studied in four bovine muscles with widely varying characteristics, the Masseter, Longissimus thoracis, Cutaneus trunci and Diaphragma. Different complementary techni...

journal_title：Journal of muscle research and cell motility

authors： Picard B,Robelin J,Pons F,Geay Y

更新日期：1994-08-01 00:00:00

abstract：:The effects of 2,3-butanedione monoxime (BDM) on contraction characteristics were studied at 5 degrees C in single intact fibres isolated from the tibialis anterior muscle of the frog. The force-velocity relation was determined using the controlled-velocity method in either whole fibres or short fibre segments in whic...

journal_title：Journal of muscle research and cell motility

authors： Bagni MA,Cecchi G,Colomo F,Garzella P

更新日期：1992-10-01 00:00:00

abstract：:Homozygous calsequestrin 2 (CASQ2) point mutations leads to catecholaminergic polymorphic ventricular tachycardia: a common pathogenetic feature appears to be the drastic reduction of mutant CASQ2 in spite of normal transcription. Comparative biochemical analysis of R33Q and D307H knock in mutant mice identifies diffe...

journal_title：Journal of muscle research and cell motility

authors： Valle G,Arad M,Volpe P

更新日期：2020-09-01 00:00:00

abstract：:The non-hydrolysable ATP analogue, beta,gamma-imido-adenosine-5'-triphosphate (AMPPNP, adenylilimidodiphosphate) does not reduce the stiffness of demembranated sea urchin sperm flagella measured in the rigor state in the absence of MgATP2- and does not cause relaxation of rigor bends. The competitive inhibitions provi...

journal_title：Journal of muscle research and cell motility

authors： Okuno M,Brokaw CJ

更新日期：1981-03-01 00:00:00

abstract：:The hypothesis that calmodulin (CaM) may act as a positive modulator of junctional SR Ca2+-release channel/ ryanodine receptor (RyRl) rests largerly on the demonstrated capacity of CaM to interact structurally and functionally with RyRl at pCa > 8 (Tripathy et al., 1995). The goal of the present [3H]-ryanodine binding...

journal_title：Journal of muscle research and cell motility

authors： Damiani E,Margreth A

更新日期：2000-01-01 00:00:00

abstract：:Five monoclonal antibodies that react with different regions of myosin light chain 1 from human ventricular myocardial muscle were used to obtain information on interactions between the light chain 1 and heavy chains and generally on the tertiary structure of the light chain 1 within the myosin head. We performed West...

journal_title：Journal of muscle research and cell motility

authors： Cornillon B,Cathiard AM,Eldin P,Anoal M,Cardinaud R,Liautard JP,Le Cunff M,Mornet D,Pons F,Leger J

更新日期：1992-06-01 00:00:00

abstract：:Heat rate and tension were measured during the steady state of isovelocity shortening in frog sartorius muscles at two speeds (7.5 and 2.0 mm s-1) through two ranges of the length-tension curve: 1.11 to 1.01 L0 and 1.01 to 0.91 L0. Both heat rate and mechanical power were higher at short length than at long length. Th...

journal_title：Journal of muscle research and cell motility

authors： Gilbert SH

更新日期：1986-04-01 00:00:00

abstract：:Our current understanding of the structure of the thin filaments of muscle and the molecular mechanism by which thin filaments regulate muscle contraction are reviewed and discussed. We focus, in particular, on the crucial role played by Jean Hanson in these studies and on later contributions from those whose work she...

journal_title：Journal of muscle research and cell motility

authors： Lehman W,Craig R

更新日期：2004-01-01 00:00:00

abstract：:The aim of the study was to investigate sex-related differences in contractile properties, parameters of action potentials, and mechanisms of force regulation of motor units in the rat soleus muscle, which is a frequent experimental model in animal research. It was revealed that the mean mass of the muscle in males wa...

journal_title：Journal of muscle research and cell motility

authors： Drzymała-Celichowska H,Krutki P

更新日期：2015-06-01 00:00:00

abstract：:Myosin heavy chain kinase activity was identified in the high speed supernate of lysed Dictyostelium amoebae and was precipitated by 30-50% ammonium sulphate. In low ionic strength buffer, the activity bound tightly to a Cibacron Blue Sepharose column and eluted as a single peak with 1.0 M NaCl. Gel filtration chromat...

journal_title：Journal of muscle research and cell motility

authors： Kuczmarski ER

更新日期：1986-12-01 00:00:00

abstract：:Under muscle disuse conditions decrease of expression of MyHC of slow type, and sometimes of type IIa, as well as upregulation of expression of IIb and IId/x isoforms were observed. Through dephosphorylation and entry of NFAT molecules to the nucleus calcineurin/NFATc1 signaling pathway promotes upregulation of the sl...

journal_title：Journal of muscle research and cell motility

authors： Lomonosova YN,Turtikova OV,Shenkman BS

更新日期：2016-04-01 00:00:00

abstract：:Cytokinesis is the mechanical process that allows the simplest unit of life, the cell, to divide, propagating itself. To divide, the cell converts chemical energy into mechanical energy to produce force. This process is thought to be active, due in large part to the mechanochemistry of the myosin-II ATPase. The cell's...

journal_title：Journal of muscle research and cell motility

authors： Robinson DN,Girard KD,Octtaviani E,Reichl EM

更新日期：2002-01-01 00:00:00

abstract：:Small but statistically significant shifts (hysteresis) between the up (increasing tension direction) and down (decreasing tension) pCa/tension relation for several muscle types of the rabbit and rat were found. The largest shift is, at most, 0.093 p units or 60% of that reported for the barnacle muscle. The direction...

journal_title：Journal of muscle research and cell motility

authors： Brandt PW,Gluck B,Mini M,Cerri C

更新日期：1985-04-01 00:00:00

abstract：:Single twitch muscle fibres have been isolated from various parts of the iliofibularis muscle of Xenopus laevis. After measurements of their isotonic contractile properties, myosin extraction was performed on individual fibres and the extract analysed by various forms of gel electrophoresis. In agreement with previous...

journal_title：Journal of muscle research and cell motility

authors： Lännergren J

更新日期：1987-06-01 00:00:00

abstract：:White muscle fibres from dogfish were used to compare the energetic costs of shortening by fully active muscle and by relaxing muscle. The muscle preparation was tetanized for 0.6 s and shortened either during stimulation or during relaxation. The distance shortened was 1 mm (about 15% L0, the muscle length optimum fo...

journal_title：Journal of muscle research and cell motility

authors： Lou F,Curtin NA,Woledge RC

更新日期：1998-10-01 00:00:00

abstract：:The effects of a ramp stretch (amplitude <6% muscle fibre length (L0), speed < 13L0 s(-1)) on twitch tension and twitch tension re-development were examined in intact mammalian (rat) fast and slow muscle fibre bundles. The experiments were done in vitro at 20 degrees C and at an initial sarcomere length of 2.68 microm...

journal_title：Journal of muscle research and cell motility

authors： Mutungi G,Ranatunga KW

更新日期：2001-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) are generated in skeletal muscle both during the rest and contractile activity. Myogenic cells are equipped with antioxidant enzymes, like superoxide dismutase, catalase, glutathione peroxidase, γ-glutamylcysteine synthetase and heme oxygenase-1. These enzymes not only neutralise excessiv...

journal_title：Journal of muscle research and cell motility

authors： Kozakowska M,Pietraszek-Gremplewicz K,Jozkowicz A,Dulak J

更新日期：2015-12-01 00:00:00

abstract：:The myosin light chains of slow muscles from different species have been examined two-dimensional gel electrophoresis. While the myosin light chain 2S of mammalian soleus muscles (rabbit, rat and guinea-pig) could not be distinguished from that of avian anterior latissimus dorsi (chicken and turkey), the 1S light chai...

journal_title：Journal of muscle research and cell motility

authors： Carraro U,dalla Libera L,Catani C

更新日期：1981-09-01 00:00:00

abstract：:The regulated assembly of actin filaments is essential in nearly all cell types. Studying actin assembly dynamics can pose many technical challenges. A number of these challenges can be overcome by using microfluidics to observe and manipulate single actin filaments under an optical microscope. In particular, microflu...

journal_title：Journal of muscle research and cell motility

authors： Wioland H,Suzuki E,Cao L,Romet-Lemonne G,Jegou A

更新日期：2020-03-01 00:00:00