Distribution of calcitonin gene-related peptide immunoreactivity in vestibular efferent neurons of the chinchilla.

abstract：:In our companion paper (Le Calvez et al., 1998), the levels of distortion product otoacoustic emissions (DPOAE) were collected in the ears of CD1 mice with progressive degeneration of cochlear outer hair cells (OHC). Their comparison to standard functional measurements such as auditory-evoked brainstem responses (ABR)...

journal_title：Hearing research

authors： Le Calvez S,Guilhaume A,Romand R,Aran JM,Avan P

更新日期：1998-06-01 00:00:00

abstract：:Doppler vibrometers are used by many research groups to monitor the motion of the tympanic membrane (TM) and of middle ear ossicles for in vivo and in vitro studies. Power densities in these applications reach 80 W/cm(2). To determine the safe limit of exposure, a cw dye laser at a wavelength of 633 nm was used to inv...

journal_title：Hearing research

authors： Foth H,Färber S,Gauer A,Wagner R

更新日期：2000-04-01 00:00:00

abstract：:Binaural hearing confers many beneficial functions but our understanding of its underlying neural substrates is limited. This study examines the bilateral synaptic assemblies and binaural computation (or integration) in the central nucleus of the inferior colliculus (ICc) of the auditory midbrain, a key convergent cen...

journal_title：Hearing research

authors： He N,Kong L,Lin T,Wang S,Liu X,Qi J,Yan J

更新日期：2017-11-01 00:00:00

abstract：:Progress in amino acid sequencing of two low-molecular weight acidic proteins of unknown function which are present at high concentrations in the organ of Corti is reported. These two proteins, provisionally termed OCP1 and OCP2, were originally demonstrated by two-dimensional polyacrylamide gel electrophoresis; their...

journal_title：Hearing research

authors： Thalmann I,Suzuki H,McCourt DW,Comegys TH,Thalmann R

更新日期：1993-01-01 00:00:00

abstract：:Chromogranin A (CgA) belongs to the family of chromogranin peptides which are contained in large dense-core vesicles. The novel CgA fragment catestatin (bovine CgA(344-364); RSMRLSFRARGYGFRGPGLQL) is a potent inhibitor of catecholamine release by acting as a nicotinic cholinergic antagonist. Catestatin is a recently c...

journal_title：Hearing research

authors： Bitsche M,Mahata SK,Marksteiner J,Schrott-Fischer A

更新日期：2003-10-01 00:00:00

abstract：:Thresholds to sinusoidal and biphasic pulsatile electrical stimuli were measured in two patients with electrodes positioned on the cochlear nucleus. The threshold functions differ from those observed in patients with scala tympani electrodes, primarily at low sinusoidal frequencies and long pulse widths. This differen...

journal_title：Hearing research

authors： Shannon RV

更新日期：1989-06-15 00:00:00

abstract：:Spike potentials were recorded from single, afferent fibres in the pigeon auditory nerve. Pure-tone stimuli were presented in quiet and in combination with wide band noise. Presented alone, tones produced tuned response areas; noise generally drove spike rate to well above the spontaneous rate measured in quiet. When ...

journal_title：Hearing research

authors： Hill KG,Mo J,Stange G

更新日期：1989-05-01 00:00:00

abstract：:In the developing inner ear, a naturally occurring programmed cell death of cochleovestibular ganglion (CVG) neurons as well as peripheral and central target-derived trophic effects on survival of embryonic CVG neurons are known. To further analyze these target derived trophic interactions, spiral ganglion explants ob...

journal_title：Hearing research

authors： Lefebvre PP,Weber T,Rigo JM,Staecker H,Moonen G,Van De Water TR

更新日期：1992-03-01 00:00:00

abstract：:In Menière's disease, the increase of extracellular potassium concentration in the perilymph is thought to play a key role in determining the progressive loss of cochlear hair cells. In this paper, we describe a serum-free culture preparation of hair cells from 5 day-old rat and report the release by the cochlea, in r...

journal_title：Hearing research

authors： Lefebvre PP,Weber T,Rigo JM,Delree P,Leprince P,Moonen G

更新日期：1990-08-01 00:00:00

abstract：:Averaged auditory evoked potentials (AEPs) to bilaterally presented 100 Hz click trains were recorded from multiple sites simultaneously within Heschl's gyrus (HG) and on the posterolateral surface of the superior temporal gyrus (STG) in epilepsy-surgery patients. Three auditory fields were identified based on AEP wav...

journal_title：Hearing research

authors： Brugge JF,Volkov IO,Oya H,Kawasaki H,Reale RA,Fenoy A,Steinschneider M,Howard MA 3rd

更新日期：2008-04-01 00:00:00

abstract：:A technique was devised in order to study the fast electromechanical length changes of outer hair cells at low stimulus levels. Solitary outer hair cells were drawn into a glass microchamber. Length changes were evoked by the application of transcellular potentials and were detected with a photodiode. The method is no...

journal_title：Hearing research

authors： Evans BN,Hallworth R,Dallos P

更新日期：1991-04-01 00:00:00

abstract：:The aim of this study was to examine the activities of hASCs (Human Adipose tissue Derived Stem Cells) on experimental autoimmune hearing loss (EAHL) and how human stem cells regenerated mouse cochlea cells. We have restored hearing in 19 years old white female with autoimmune hearing loss with autologous adipose tiss...

journal_title：Hearing research

authors： Yoo TJ,Du X,Zhou B

更新日期：2015-12-01 00:00:00

abstract：:We have compared the effects of microiontophoretic application of the GABA(A)-receptor antagonists bicuculline (BIC) and gabazine (SR95531) on responses to pure tones and to sinusoidally amplitude-modulated (AM) tones in cells recorded extracellularly from primary auditory cortex (AI) of Mongolian gerbils. Besides sim...

journal_title：Hearing research

authors： Kurt S,Crook JM,Ohl FW,Scheich H,Schulze H

更新日期：2006-02-01 00:00:00

abstract：:Single-unit recordings from neurons in the torus semicircularis of Rana ridibunda were analyzed to determine the degree to which these neurons can detect acoustic stimuli superimposed on continuous, broad-band noise. In the first series of trials the stimuli were tone pulses 25 ms long, 5 dB above threshold, and at th...

journal_title：Hearing research

authors： Joermann G

更新日期：1988-09-15 00:00:00

abstract：:A linear (frequency-domain) model of the cat cochlea (implemented in both 1- and 2-dimensional versions) has been developed which uses outer hair cell (OHC) forces in a geometry which includes the longitudinal (base-to-apex) tilt of the outer hair cells (OHCs). When positive (contractile) real OHC force-constants are ...

journal_title：Hearing research

authors： Geisler CD,Sang C

更新日期：1995-06-01 00:00:00

abstract：:The ear of the goldfish (Carassius auratus) contains three otolithic endorgans: the saccule, lagena, and utricle. The saccule has an auditory function in most teleost fishes for whom data are available, and there is evidence that the lagena is also an auditory endorgan in the goldfish. This study was conducted to comp...

journal_title：Hearing research

authors： Edds-Walton PL,Popper AN

更新日期：2000-03-01 00:00:00

abstract：:Electrical stimulation of the cochlea is known to cause auditory sensations in humans and other animals. It also has been shown to produce emissions of sound from the inner ear. In the current study we investigate the relationship between electrically induced motion of the basilar membrane (BM) and the production of o...

journal_title：Hearing research

authors： Nuttall AL,Ren T

更新日期：1995-12-01 00:00:00

abstract：:Tinnitus is a perception of sound that can occur in the absence of an external stimulus. A brief review of electroencephalography (EEG) and magnetoencephalography (MEG) literature demonstrates that there is no clear relationship between tinnitus presence and frequency band power in whole scalp or source oscillatory ac...

journal_title：Hearing research

authors： Pierzycki RH,McNamara AJ,Hoare DJ,Hall DA

更新日期：2016-01-01 00:00:00

abstract：:The present study measured interference-response areas (IRAs) for distortion-product otoacoustic emissions (DPOAEs) at 2f(1)-f(2), 3f(1)-2f(2), and 2f(2)-f(1). The IRAs were obtained in either awake or anesthetized rabbits, or in anesthetized guinea pigs and mice, by sweeping the frequencies and levels of an interfere...

journal_title：Hearing research

authors： Martin GK,Stagner BB,Jassir D,Telischi FF,Lonsbury-Martin BL

更新日期：1999-10-01 00:00:00

abstract：:In previous studies describing the effects of electrically stimulating the olivocochlear bundle, it seems possible that both medial and lateral (MOC and LOC) efferents may have been stimulated. To selectively stimulate MOC efferents, we used an electrode placed at the origin of the MOC efferents in the brainstem (MOC ...

journal_title：Hearing research

authors： Guinan JJ Jr,Gifford ML

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVES:Investigation of bone conduction sound propagation by osseous and non-osseous pathways and their interactions based upon the stimulation site and coupling method of the actuator from a bone conduction hearing aid (BCHA). METHODS:Experiments were conducted on five Thiel embalmed whole head cadaver specimens....

journal_title：Hearing research

authors： Dobrev I,Sim JH,Pfiffner F,Huber AM,Röösli C

更新日期：2019-07-01 00:00:00

abstract：:Kanamycin (KM)-induced changes in expression of the gene for glutamate-aspartate transporter (GLAST) in the rat cochlea were analyzed by Northern blotting. With the administration of KM (600 mg/kg/day) once daily for 20 days, the expression of GLAST mRNA gradually increased and reached a peak on day 20. Although the e...

journal_title：Hearing research

authors： Matsuda K,Ueda Y,Doi T,Tono T,Haruta A,Toyama K,Komune S

更新日期：1999-07-01 00:00:00

abstract：:Following hair cell elimination in severely traumatized cochleae, differentiated supporting cells are often replaced by a simple epithelium with cuboidal or flat appearance. Atoh1 (previously Math1) is a basic helix-loop-helix transcription factor critical to hair cell differentiation during mammalian embryogenesis. F...

journal_title：Hearing research

authors： Izumikawa M,Batts SA,Miyazawa T,Swiderski DL,Raphael Y

更新日期：2008-06-01 00:00:00

abstract：:Healthy guinea pigs were exposed to broad band noise at levels between 95 and 115 dBA for 7 days. A significant decrease of the sound-induced cochlear responses, together with a substantial increase of the endocochlear potential, was observed in guinea pigs exposed to noise at 105 or 115 dBA. Microsamples of the endol...

journal_title：Hearing research

authors： Konishi T,Salt AN,Hamrick PE

更新日期：1979-12-01 00:00:00

abstract：:The spectro-temporal receptive field (STRF) of an auditory neuron represents those characteristics of the sound stimulus in both the time and frequency domain that affect the firing probability of the neuron. The STRF is determined under stationary stimulus conditions for Gaussian wide-band noise. It has been demonstr...

journal_title：Hearing research

authors： Eggermont JJ,Aertsen AM,Johannesma PI

更新日期：1983-05-01 00:00:00

abstract：:Drugs of the salicylate family (aspirin-like drugs) are reversibly ototoxic. Electrophysiologic and ultrastructural evidence suggests an impairment of the sensory hair cells of the cochlea following salicylate treatment. In addition, since these drugs can cause vasoconstriction, the ototoxicity of salicylates may also...

journal_title：Hearing research

authors： Didier A,Miller JM,Nuttall AL

更新日期：1993-09-01 00:00:00

abstract：:The latency of the N1 component of tone burst evoked compound action potentials was examined in chinchilla following acute pure-tone trauma. At and below the trauma frequency (4 kHz) the N1 latency at threshold generally increased, while above the trauma frequency it decreased; tonotopically paralleling pitch shifts o...

journal_title：Hearing research

authors： Sikora MA,Morizono T

更新日期：1983-07-01 00:00:00

abstract：:Noise exposure and the subsequent hearing loss are well documented aspects of military life. Numerous studies have indicated high rates of noise-induced hearing injury (NIHI) in active-duty service men and women, and recent statistics from the U.S. Department of Veterans Affairs indicate a population of veterans with ...

journal_title：Hearing research

authors： Smalt CJ,Lacirignola J,Davis SK,Calamia PT,Collins PP

更新日期：2017-06-01 00:00:00

abstract：:We investigated the effects of intracochlear electrical stimulation (ICES) on auditory pathways of neonatal rat deafened by daily amikacin injections. Expression of mRNAs encoding ionotropic glutamate receptor subunits such as alpha-amino-3-hydroxy-5-methyl-4-isoxazole (AMPA) and N-methyl-D-aspartate (NMDA), and gamma...

journal_title：Hearing research

authors： Liao WH,Van Den Abbeele T,Herman P,Frachet B,Huy PT,Lecain E,Marianowski R

更新日期：2000-12-01 00:00:00

abstract：:Experiments on the flow-sensitive lateral line system of fishes have provided important insights into the function and sensory transduction of vertebrate hair cells. A common experimental approach has been to pharmacologically block lateral line hair cells and measure how behavior changes. Cobalt chloride (CoCl2) bloc...

journal_title：Hearing research

authors： Stewart WJ,Johansen JL,Liao JC

更新日期：2017-07-01 00:00:00