Abstract:
:An ICR outbred suckling mouse model of cryptosporidiosis was used to explain some of the variability associated with experimental Cryptosporidium parvum infections in neonate mice. Fourty-four groups of 12 mice each, ranging in age from 4-12 days, each received 1.0 x 10(4) CsCl purified oocysts per os in 5 microns PBS. At 6 days post-inoculation (PI), mice were killed by CO2 overdose and individually weighed. Intestines were then homogenized and oocysts were quantified by hemacytometer. Results revealed that both age and weight have pronounced effects on numbers of oocysts produced in vivo, with larger and older mice producing higher numbers of parasites. Mice 8-9 days of age at the time of inoculation displayed the least amount of weight dependent variability, produced the highest numbers of oocysts, and were judged to be superior over other ages for pharmaceutical screening. Significant reductions in numbers of oocysts occurred in mice inoculated at 10 days of age, and only a few oocysts were found in mice inoculated at 11-12 days of age. These studies suggest that at least some data on Cryptosporidium generated from suckling mouse studies to date are probably unreliable and should be viewed skeptically.
journal_name
Folia Parasitol (Praha)journal_title
Folia parasitologicaauthors
Upton SJ,Gillock HHsubject
Has Abstractpub_date
1996-01-01 00:00:00pages
101-6issue
2eissn
0015-5683issn
1803-6465journal_volume
43pub_type
杂志文章abstract::The type species of the genus Glossocercus Chandler, 1935, G. cyprinodontis Chandler, 1935, was described as metacestode (larval stage) from the mesentery of the sheepshead minnow fish (Cyprinodon variegatus Lacépède) from Galveston Bay, Texas. The description was based on the morphology of the rostellar hooks; howeve...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2013.005
更新日期:2013-02-01 00:00:00
abstract::In Senegal, several areas provide great potential for agriculture and animal production, but African animal trypanosomosis (AAT) is one of the major constraints to the development of more effective livestock production systems. A study was conducted to assess the current situation of AAT in this country. Surveys were ...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2015.044
更新日期:2015-08-18 00:00:00
abstract::Margaritaella gracilis gen. n. et sp. n. (Proteocephalidea: Proteocephalinae) found in the intestine of Callichthys callichthys (Linnaeus) from the Paraná River basin is described. The new genus is placed in the Proteocephalinae because of the medullary position of the genital organs. It differs from all known genera ...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2012.015
更新日期:2012-06-01 00:00:00
abstract::Specimens of the nematode genus Rhabdochona Railliet, 1916 (Rhabdochonidae) were collected during helminthological examination of four species of cyprinid fishes in two rivers of the Amur River basin in the Russian Far East (Primorsky Region) in June 2011. Detailed light microscopical (LM) and scanning electron micros...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2012.027
更新日期:2012-09-01 00:00:00
abstract::Laboratory animals (mice and guinea pigs) were infected with the isolates of Coxiella burnetii (Derrick, 1939) obtained from bovine milk (M18 and M35) and the ticks Ixodes ricinus (Linnaeus, 1758) and Dermacentor marginatus (Sulzer, 1776) (Kl3 and Kl6, respectively), and with the reference strain Nine Mile. Neither mo...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Microsporidia constitute a large group of obligate intracellular protozoan parasites that inject themselves into host cells via the extrusion apparatus of the infective spore stage. Although the injection process is poorly understood, its energy source is thought to reside in the posterior vacuole that swells signific...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2005.014
更新日期:2005-05-01 00:00:00
abstract::In the course of the study "Toxoplasmosis and Prematurity" 330 blood samples from twins were examined. Our findings in a series of 21 premature twins (maternal sera were also examined) are reported in this paper. Toxoplasma antibodies were detected by the Sabin-Feldman test and specific IgM antibodies by the Remington...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::Toxoplasmosis is a potentially fatal complication after hematopoietic cell transplantation (HCT). Pre-transplant seropositivity of graft recipient to Toxoplasma gondii (Nicolle et Manceaux, 1908) is an important factor for disease reactivation after HCT. As toxoplasmosis epidemiology varies all over the world, we perf...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2019.019
更新日期:2019-11-11 00:00:00
abstract::In field and laboratory conditions new data were obtained concerning the life cycle of the nidicolous tick Ixodes laguri. The development of this tick was studied in experimental nests of the European suslik and a two-year cycle of I. laguri was demonstrated. However, the materials obtained indicate that a longer cycl...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::The development of the nematode Procamallanus (Spirocamallanus) neocaballeroi (Caballero-Deloya, 1977), an intestinal parasite of the characid fish, Astyanax fasciatus (Cuvier) in Mexico, was studied in the experimental copepod intermediate host, Mesocyclops sp. After the copepod's ingestion of free first-stage larvae...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::This study was undertaken to attempt to identify correlations between microsporidial seroprevalence data in man, clinical diseases and groups of people at the risk of HIV/AIDS infection. Groups of patients were selected according to the predilection of members of the genus Encephalitozoon for nervous and kidney tissue...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::A relatively high rate of mortality among engorged females of Ornithodoros moubata (Murray, 1877) was observed in our laboratory colony. The general aim of the study was to identify the causative agent responsible for this mortality. The diagnostic tests were performed by Yeast Identification Service (CBS-Delft, Nethe...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Effect of temperature on the sporogonic cycle of Plasmodium berghei (NK 65) has been studied in vector Anopheles stephensi. To determine the optimum temperature for development of parasite, fed mosquitoes were kept at 16 +/- 1 degree C, 19 +/- 1 degree C and 26 +/- 1 degree C temperature. The temperature 19 +/- 1 degr...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::The adult morphology is described and illustrated of Neoplagioporus kajika sp. n. (Digenea: Opecoelidae) found in the Japanese fluvial sculpin Cottus pollux Günther (Osteichthyes: Scorpaeniformes: Cottidae) collected in the Naka River at Terase Bridge, Narutake, Nakagawa Town, Fukuoka Prefecture, Kyushu, Japan. This n...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2006.026
更新日期:2006-09-01 00:00:00
abstract::Blood smears prepared from the peripheral blood of 20 wild caught Amietia quecketti (Boulenger) from the North-West University Botanical Gardens, North West Province, South Africa, were examined for the presence of haemogregarines. A haemogregarine species comparative in morphology, host and geographical locality to t...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
abstract::A new genus of the family Capillariidae, Tridentocapillaria gen. n., has been established. A type species is Tridentocapillaria tridens (Dujardin, 1845) comb. n. Other species of this genus are T. eurycerca (Oschmarin et Parukhin, 1963) comb. n., T. parusi (Wakelin, Schmidt et Kuntz, 1970) comb. n., and T. javanensis ...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Except other functions, surface saccharide residues on trematode larvae are supposed either to be the targets of the intermediate (molluscan) and final host immune systems, or to represent candidates for molecular mimicry. Therefore, changes in surface saccharide patterns during the development of the avian schistosom...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::Faecal samples from 162 wild animals were collected from 32 distinct sites of Łęczyńsko-Włodawskie Lakeland (eastern Poland). The presence of Giardia duodenalis (Stiles, 1902) was assessed by a Direct Fluorescence Assay (DFA) and by Polymerase Chain Reaction (PCR) and sequencing of a fragment of the beta-giardin gene....
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2015.042
更新日期:2015-07-30 00:00:00
abstract::Soricinia tripartita Zarnowski, 1955 is redescribed on the basis of specimens from the type host Sorex araneus Linnaeus from Lithuania, Latvia and Russia (Republic of Karelia and Republic of Komi - a new geographical record) as well as from Sorex satunini Ognev and Sorex volnuchini Ognev from Russia (Nalchik Area in t...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:2014-04-01 00:00:00
abstract::One thousand three hundred seventy three fish specimens of eight different species from the vicinity of Kyiv, Ukraine, were examined for the presence of trypanosomes and 921 individuals were found to be infected. The prevalence of infection ranged from 24% in freshwater bream, Abramis brama (Linnaeus), to 100% in spin...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:2014-12-01 00:00:00
abstract::The present study evaluates the performance of OptiMAL-IT test and nested PCR assay in detection of malaria parasites. A total of 76 randomly selected blood samples collected from two malaria endemic areas were tested for malaria parasites using microscopy and OptiMAL-IT test in the field. PCR assays were performed in...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2013.041
更新日期:2013-11-01 00:00:00
abstract::During the 3rd Czechoslovak mountaineering expedition to the Himalaya in the spring 1973 ticks of the family Ixodidae were collected from small mammals and additionally from pastured sheep, and humans. The tick material represented the following species: Ixodes (P.) ovatus Neumann, 1899, Ixodes (I.) acutitarsus (Karsc...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::Numerous specimens of Calydiscoides spp. from Lethrinus nebulosus and L. harak, and fewer specimens from L. lentjan, L. ravus and L. obsoletus, collected off New Caledonia, South Pacific, were examined. Three species of Calydiscoides were recognized. Calydiscoides difficilis (Yamaguti, 1953) Young, 1969 was generally ...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2007.026
更新日期:2007-09-01 00:00:00
abstract::We studied the specificity of the individual developmental stages of Fasciola hepatica for evoking immune response of the host to reinfection with this parasite, whereby the primary infection was eliminated by a dose of 150 mg/kg diamphenethide administered in various intervals. In rats we observed a state of hypersen...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::Based on the study of type material, two new genera of cestodes (Cyclophyllidea: Anoplocephalidae) are proposed for Paranoplocephala Lüihe, 1910 sensu lato species from African rodents. Afrojoyeuxia gen. n., proposed for A. gundii (Joyeux, 1923) comb. n. from Ctenodactylus gundi (Rothmann) (Hystricomorpha: Ctenodactyl...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2013.051
更新日期:2013-11-01 00:00:00
abstract::The behavioural manipulation hypothesis posits that parasites can change the behaviour of hosts to increase the reproductive fitness of the parasite. The protozoan parasite Toxoplasma gondii fits this description well. Sexual reproduction occurs in the cat intestine, from which highly stable oocysts are excreted in fa...
journal_title:Folia parasitologica
pub_type: 杂志文章,评审
doi:10.14411/fp.2010.011
更新日期:2010-06-01 00:00:00
abstract::Twenty two percent (22/98) of intertidal fishes of 10 species captured in South Africa at Koppie Alleen, De Hoop Nature Reserve (south coast) and Mouille Point, Cape Town (west coast), harboured single or combined infections of haemogregarines, trypanosomes and an intraerythrocytic parasite resembling a Haemohormidium...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2006.031
更新日期:2006-12-01 00:00:00
abstract::Bloodforms of Trypanosoma brucei brucei STIB 247 taken from rats and containing more than 80 per cent short stumpy forms, differentiated in vitro to procyclic forms in medium SDM 79 (Brun and Schönenberger 1979), enriched with 3 mmol.dm-3 cis-aconitate. Cell division was abolished by the addition of hydroxyurea (200 m...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Malate dehydrogenase (EC 1.1.1.37.) (MDH) was purified to apparent homogeneity from the cytosolic fraction of the protozoan Trichomonas vaginalis Donné. The four step purification included ion-exchange chromatography (DEAE-Sephacel and Q-Sepharose, elution with NaCl) and affinity chromatography (Reactive Red Agarose, ...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Synbranchiella gen. n. is proposed to accommodate Synbranchiella mabelae sp. n. (Proteocephalidae: Monticelliinae) from the intestine of the marbled swamp eel Synbranchus marmoratus Bloch, in the River Colastiné, a tributary of the middle River Paraná in Argentina. The new genus is placed in the Monticelliinae because...
journal_title:Folia parasitologica
pub_type: 杂志文章
doi:10.14411/fp.2017.015
更新日期:2017-05-05 00:00:00