Update in preimplantation genetic diagnosis: successes, advances, and problems.

abstract：PURPOSE OF REVIEW:The past 15 years have seen a five-fold increase in the incidence of acquired heart disease as a cause of maternal mortality in the UK, and advances in the surgical correction of congenital heart disease have enabled many more women to survive childhood and present at the antenatal clinic. This review...

journal_title：Current opinion in obstetrics & gynecology

authors： Curry R,Swan L,Steer PJ

更新日期：2009-12-01 00:00:00

abstract：:Current ultrasound equipment allows the antenatal identification of many central nervous system anomalies from early gestation. In selected cases, special techniques (transvaginal sonography, three-dimensional ultrasound, colour Doppler) may enhance the diagnostic potential. Diagnostic accuracy, however, remains heavi...

journal_title：Current opinion in obstetrics & gynecology

authors： Pilu G,Perolo A,Falco P,Visentin A,Gabrielli S,Bovicelli L

更新日期：2000-04-01 00:00:00

abstract：:Acquired immunodeficiency virus infections had recently been the leading cause of death in minority women of reproductive age in several urban cities in the United States. In addition, more than 80% of infants with human immunodeficiency virus type 1 infection acquired the infection perinatally. These alarming data ha...

journal_title：Current opinion in obstetrics & gynecology

authors： Sison AV

更新日期：1992-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Expanded carrier screening, which detects carriers for a large number of autosomal recessive and X-linked diseases, is increasing in clinical utilization. A recent joint statement from multiple professional societies, in addition to a growing literature base, offers perspective on rationale, decision ...

journal_title：Current opinion in obstetrics & gynecology

authors： Lazarin GA,Goldberg JD

更新日期：2016-04-01 00:00:00

abstract：:Vaginal birth has been recognized as being potentially traumatic to the pelvic floor. It is important that contributory obstetric factors are identified and their occurrence minimized. Women who have sustained significant anal sphincter injury are at greater risk of further damage and faecal incontinence with subseque...

journal_title：Current opinion in obstetrics & gynecology

authors： Fitzpatrick M,O'Herlihy C

更新日期：2000-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the role of mullerian inhibiting substance in the context of female reproduction. RECENT FINDINGS:Serum and follicular fluid mullerian inhibiting substance can be measured by commercially available enzyme-linked immunosorbent assay kits. Mullerian inhibiting substance is secreted from small...

journal_title：Current opinion in obstetrics & gynecology

authors： Nakhuda GS

更新日期：2008-06-01 00:00:00

abstract：:This review explores the recent experience with, and the basis for, the use of selective estrogen receptor modulators to treat and prevent breast cancer. As new agents are unveiled, they will continue to be tested against tamoxifen. A number of new selective estrogen receptor modulators are in clinical development in ...

journal_title：Current opinion in obstetrics & gynecology

authors： Bentrem DJ,Jordan VC

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Robotic surgery is rapidly taking the place of laparoscopy in many gynecologic oncology practices. Numerous practitioners have published their experience with this new technology. A review of their findings is timely and relevant. RECENT FINDINGS:The majority of case series of robotic surgery for hys...

journal_title：Current opinion in obstetrics & gynecology

authors： Bandera CA,Magrina JF

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:With over 50 million abortions annually and 25% of pregnancies ending in abortion worldwide, abortion is one of the most common medical procedures. Yet abortion-related topics are glaringly absent from medical school curricula in the USA with half of medical schools including no formal training or onl...

journal_title：Current opinion in obstetrics & gynecology

authors： Burns RM,Shaw KA

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Immune checkpoint blockade (ICB) is a promising area of cancer therapeutic research. Therapies targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) mechanism of tumor immune evasion have resulted in durable responses in many difficult-to-treat tumor types. While these...

journal_title：Current opinion in obstetrics & gynecology

authors： Chin CD,Fares CM,Konecny GE,Rao J

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The principles of neonatal neurological protection following intrapartum hypoxia are briefly reviewed. The physiological principles behind the use of cardiotocograph patterns in defining the timing and mechanism of fetal hypoxia and injury are then demonstrated. RECENT FINDINGS:Fetal neurological inj...

journal_title：Current opinion in obstetrics & gynecology

authors： Schifrin BS,Ater S

更新日期：2006-04-01 00:00:00

abstract：:The principles of managed care are more difficult to apply to preventive medical treatments, such as hormone replacement therapy, than to the investigation and treatment of established disease. In addition to an ageing society with increased health demands, the use of hormone replacement therapy is increasing in most ...

journal_title：Current opinion in obstetrics & gynecology

authors： Wardle PG

更新日期：1997-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Growth hormone (GH) has been used as an adjunct in ovulation induction and IVF for 25 years, particularly as an adjunct to ovarian stimulation for women who had a previous poor response to stimulation in an IVF cycle. It does not have US Food and Drug Administration approval for this use. Unfortunatel...

journal_title：Current opinion in obstetrics & gynecology

authors： Hart RJ,Rombauts L,Norman RJ

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Because of widespread availability of highly active antiretroviral therapy in the developed world, a large proportion of children with perinatally acquired HIV have survived to adolescence and young adulthood. Although their survival is remarkable, many now experience the long-term effects of HIV infe...

journal_title：Current opinion in obstetrics & gynecology

authors： Koenig LJ,Nesheim S,Abramowitz S

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This article will review recent changes in the standard of care for olaparib, niraparib, and rucaparib, as well as ongoing trials evaluating this class of drugs in combination with antiangiogenic agents and PD-1/PD-L1 inhibitors. RECENT FINDINGS:Niraparib received FDA approval for use in patients wit...

journal_title：Current opinion in obstetrics & gynecology

authors： Washington CR,Moore KN

更新日期：2021-02-01 00:00:00

abstract：:Urinary incontinence remains a common problem that adversely affects the quality of life of millions of women. In detrusor instability, treatment measures often lack efficacy or are accompanied by unacceptable side effects. In this review, standard treatments are discussed, together with recent pharmacologic advances ...

journal_title：Current opinion in obstetrics & gynecology

authors： Wise B,Cardozo L

更新日期：1991-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent advances in oocyte and embryo cryopreservation techniques and outcomes. RECENT FINDINGS:Vitrification is gradually replacing slow freezing due to a better survival rate after thawing. Most units use vitrification for both oocyte and blastocyst cryopreservation, as these two biolog...

journal_title：Current opinion in obstetrics & gynecology

authors： Herrero L,Martínez M,Garcia-Velasco JA

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The different patterns of autoreactivity that may account for the premature infertility observed in patients with premature ovarian failure are described. RECENT FINDINGS:Animal model studies have detailed fundamental immune dysregulatory patterns that induce ovarian failure in the context of global ...

journal_title：Current opinion in obstetrics & gynecology

authors： Tuohy VK,Altuntas CZ

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a concise review of advances in prediction of preeclampsia, highlighting the most important and interesting articles among the many published within the past months, making a clear distinction between early and late clinical forms of the condition. RECENT FINDINGS:The performance of matern...

journal_title：Current opinion in obstetrics & gynecology

authors： Scazzocchio E,Figueras F

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The management of uterine fibroids in patients requiring treatment who desire future fertility remains controversial. Myomectomy has been the most common operative procedure to improve pregnancy rates and outcomes. Uterine fibroid embolization is an increasingly popular, minimally invasive treatment f...

journal_title：Current opinion in obstetrics & gynecology

authors： Goldberg J,Pereira L

更新日期：2006-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide clinicians with a review of recent research and clinically applicable tools regarding teen pregnancy. RECENT FINDINGS:Teen pregnancy rates have declined but still remain a significant problem in the USA. Teen pregnancy prevention was identified by Centers for Disease Control and Prevention...

journal_title：Current opinion in obstetrics & gynecology

authors： McCracken KA,Loveless M

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:What controls puberty remains largely unknown and current gene mutations account for only about one-third of the apparently genetic cases of idiopathic hypogonadotropic hypogonadism. Lately important developments have occurred in this field. RECENT FINDINGS:Substantial variation in clinical expressio...

journal_title：Current opinion in obstetrics & gynecology

authors： Topaloglu AK,Kotan LD

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The development of robotic technology has facilitated the application of minimally invasive techniques for complex operations in gynecologic oncology. The objective of this article is to review the published literature regarding robotic surgery and its application to gynecologic cancer. RECENT FINDIN...

journal_title：Current opinion in obstetrics & gynecology

authors： Yim GW,Kim YT

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Selective intrauterine growth restriction (sIUGR) in twin pregnancies presents a complex management problem for the fetal medicine specialist. This review summarizes what is currently known about sIUGR pathophysiology, particularly in monochorionic pregnancies and looks at the results of early trials ...

journal_title：Current opinion in obstetrics & gynecology

authors： Townsend R,Khalil A

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The increased risk of infertility in men with varicocele is well established. Varicocelectomy has been shown to improve semen parameters and increase pregnancy rates. Yet varicocele pathophysiology is poorly understood and potential implications for testosterone production are less clear. Evidence sug...

journal_title：Current opinion in obstetrics & gynecology

authors： Tanrikut C,McQuaid JW,Goldstein M

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To present the outcome of laparoscopic resection for bowel endometriosis. RECENT FINDINGS:In the last 12 months, numerous articles have been published to demonstrate and underline the efficiency and feasibility of the laparoscopic approach in the treatment of bowel endometriosis. SUMMARY:Endometrios...

journal_title：Current opinion in obstetrics & gynecology

authors： Ruffo G,Rossini R

更新日期：2013-08-01 00:00:00

abstract：:In 1991, the abortion literature was characterized by articles relating to 1) epidemiologic issues in abortion care, 2) advances in knowledge and experience with medical abortifacients such as mifepristone (RU 486), and 3) cervical ripening prior to abortion with the use of both mifepristone and prostaglandins. Techni...

journal_title：Current opinion in obstetrics & gynecology

authors： Blumenthal PD

更新日期：1992-08-01 00:00:00

abstract：:Infertile couples who seek medical advice have one single hope: to have one or more children. Therefore, pregnancy rates per cycle of any assisted reproductive technique that include early miscarriages and ectopic pregnancies are of little interest to them. They want to know their chances of having a baby. When counse...

journal_title：Current opinion in obstetrics & gynecology

authors： Tanbo T,Abyholm T

更新日期：1996-06-01 00:00:00

abstract：:Transvaginal ultrasonography is emerging as the newest method for the early detection of structural malformations and markers of chromosomal aberrations. According to a multicenter registry on the onset of fetal anomalies, many defects are potentially detectable at an early transvaginal scan. Moreover, cystic hygroma ...

journal_title：Current opinion in obstetrics & gynecology

authors： Rottem S

更新日期：1995-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Antiphospholipid syndrome (APS) is defined as the association of thrombotic events and/or obstetric morbidity in patients persistently positive for antiphospholipid antibodies (aPL). In this review, we will highlight the most important clinical presentations of APS with a focus on the obstetric morbid...

journal_title：Current opinion in obstetrics & gynecology

authors： Schreiber K,Radin M,Sciascia S

更新日期：2017-12-01 00:00:00