Abstract:
OBJECTIVE:MRI offers many opportunities for noninvasive in vivo measurement of structure-function relationships in the human brain. Although automated methods are now available for whole-brain measurements, an efficient and valid automatic method for volume estimation of subregions such as the frontal or temporal lobes is still needed. MATERIALS AND METHODS:We adapted the Talairach atlas to the study of brain subregions. We supplemented the atlas with additional boxes to include the cerebellum. We assigned all the boxes to 1 of 12 regions of interest (ROIs) (frontal, parietal, temporal, and occipital lobes, cerebellum, and subcortical regions on right and left sides of the brain). Using T1-weighted MR scans collected with an SPGR sequence (slice thickness = 1.5 mm), we manually traced these ROIs and produced volume estimates. We then transformed the scans into Talairach space and compared the volumes produced by the two methods ("traced" versus "automatic"). The traced measurements were considered to be the "gold standard" against which the automatic measurements were compared. RESULTS:The automatic method was found to produce measurements that were nearly identical to the traced method. We compared absolute measurements of volume produced by the two methods, as well as the sensitivity and specificity of the automatic method. We also compared the measurements of cerebral blood flow obtained through [15O]H2O PET studies in a sample of nine subjects. Absolute measurements of volume produced by the two methods were very similar, and the sensitivity and specificity of the automatic method were found to be high for all regions. The flow values were also found to be very similar by both methods. CONCLUSION:The automatic atlas-based method for measuring the volume of brain subregions produces results that are similar to manual techniques. The method is rapid, efficient, unbiased, and not subject to the problems of rater drift or potentially poor interrater reliability that plague manual methods. Consequently, this method may be very useful for the study of structure-function relationships in the human brain.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Andreasen NC,Rajarethinam R,Cizadlo T,Arndt S,Swayze VW 2nd,Flashman LA,O'Leary DS,Ehrhardt JC,Yuh WTdoi
10.1097/00004728-199601000-00018subject
Has Abstractpub_date
1996-01-01 00:00:00pages
98-106issue
1eissn
0363-8715issn
1532-3145journal_volume
20pub_type
杂志文章abstract:OBJECTIVES:To investigate the coronary venous system (CVS) and its spatial relationship with coronary arteries by using 256-slice computed tomography (CT). METHODS:One hundred one patients underwent coronary CT angiography by using a 256-slice CT. In each patient, the CVS and its spatial relationship with coronary art...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000949
更新日期:2020-01-01 00:00:00
abstract::A case of external jugular venous thrombosis secondary to misplacement of central venous catheter is presented. The CT findings included enlargement of the external jugular vein, central thrombosis, and vessel wall enhancement. Computed tomography is an excellent noninvasive modality for the evaluation of suspected ve...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198505000-00036
更新日期:1985-05-01 00:00:00
abstract::Subchondral fractures in association with an intact joint space and narrowing of the joint space have not previously been reported with sacroiliac joint trauma in children. The subchondral fractures are thought to occur through the zones of cartilage proliferation and provisional calcification in the growing cartilage...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198503000-00023
更新日期:1985-03-01 00:00:00
abstract::Segmentation of vertebral bones in computed tomographic data is important as a first stage of image-based radiological tasks. However, it is a challenging problem to segment an affected spine correctly. In this study, we propose a new method of segmentation of thoracic and lumbar vertebral bodies from thin-slice compu...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181b12242
更新日期:2010-01-01 00:00:00
abstract::There is disagreement about the ability of CT to detect isolated invasion of mediastinal vessels by malignant thymoma. Diagnosis usually depends on the absence of intact fat planes between the tumor mass and the adjacent vessel. We describe a rare case of CT demonstration of direct intraluminal invasion of a malignant...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198903000-00035
更新日期:1989-03-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to evaluate predictive factors for discriminating benign from malignant intraductal mucin-producing neoplasm (IPMN) of the pancreas on multidetector row computed tomography (MDCT). MATERIALS AND METHODS:Fifty-three patients with IPMN underwent MDCT, and the imaging and pathologic...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3180676d97
更新日期:2008-03-01 00:00:00
abstract::Presented is a case of ureteral pseudodiverticulosis diagnosed by multidetector computed tomography (CT). Axial and coronal reformatted CT images revealed multiple small (2-4 mm) outpouchings of both ureters, characteristic of ureteral pseudodiverticulosis. The unenhanced CT also revealed a 6-mm stone at the left uret...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318173ebd0
更新日期:2009-03-01 00:00:00
abstract::The aim of the study was to explore the efficacy of iodine quantification with dual-energy computed tomography (DECT) in differentiating thymoma, thymic carcinoma, and thymic lymphoma. MATERIALS AND METHODS:Fifty-seven patients with pathologically confirmed low-risk thymoma (n = 16), high-risk thymoma (n = 15), thymi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000800
更新日期:2018-11-01 00:00:00
abstract::Sternal hyperostosis is characterized by prominent new bone formation and fibrosis with less pronounced areas of granulation tissue and round cell infiltration. In previously reported cases the process involved not only the sternum but adjacent bony areas as well. Depending upon the extent of disease, acquiring biopsy...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199001000-00028
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:To prospectively investigate the feasibility of an 80-kilovolt (peak) (kVp) protocol in computed tomographic venography for varicose veins of the lower extremities by comparison with conventional 120-kVp protocol. METHODS:Attenuation values and signal-to-noise ratio of iodine contrast medium (CM) were determ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3182621ea9
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:To present a novel magnetic resonance (MR) method of analysis of cerebrospinal fluid (CSF) flow dynamics. METHODS:Fifty-one subjects were explored with phase-contrast cine MR imaging. There were 36 volunteers, 9 patients with normal pressure hydrocephalus (NPH), and 6 patients with asymptomatic ventricular d...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200403000-00015
更新日期:2004-03-01 00:00:00
abstract::From a sequence of computed tomograms of two-dimensional transverse slices of a body one can build up a three-dimensional array of numbers containing spatial rather than cross-sectional information. We have developed computer methods to display a slice at arbitrary orientation through the three-dimensional object. The...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197701000-00018
更新日期:1977-01-01 00:00:00
abstract::A new examination protocol for patients with suspected meniscal or hyaline cartilage disorders is presented. Knees were imaged with a fast gradient echo imaging sequence with subsequent three-dimensional transformation. Data were transferred to an image processing system that allows reconstruction in any plane desired...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198911000-00009
更新日期:1989-11-01 00:00:00
abstract:OBJECTIVE:To evaluate stent-induced artifacts by 64-row multidetector computed tomography (MDCT). METHODS:We studied 26 stented patients with MDCT before conventional coronary angiography (CCA). The CT values were measured. Stents were classified as occluded, with significant stenosis, with nonsignificant stenosis, or...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181ddbbc0
更新日期:2010-11-01 00:00:00
abstract::An increase in the effective atomic number of blood is among the factors allowing or influencing the visualization of the major cerebral vessels on noncontrast CT. Bromine (atomic number, 50) attenuates 70 keV X-rays significantly and was responsible for a striking enhancement of the major cerebral vessels on the nonc...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198410000-00035
更新日期:1984-10-01 00:00:00
abstract::Image quality in cranial computed tomography (CT) was evaluated with phantom and patient studies on both a first (single beam) and a second (multiple beam) generation scanner. When comparable radiation doses were used, there were only minor differences in resolution, low contrast detectability, and noise level. The pa...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197807000-00020
更新日期:1978-07-01 00:00:00
abstract:OBJECTIVE:The aims of this study were to evaluate the dependence of diffusion parameters on the b values adopted for intravoxel incoherent motion diffusion-weighted magnetic resonance imaging and to investigate the application value of multiple diffusion parameters obtained from monoexponential and biexponential models...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000569
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVES:The Clot Lysis Evaluating Accelerated Resolution of Intraventricular Hemorrhage Trial phase III is a multicenter, randomized clinical trial in the management and treatment of subjects with small intracerebral hemorrhage and large intraventricular hemorrhage. Accurate localization, segmentation, and quantific...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/RCT.0b013e318245c1fa
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:Electron beam CT (EBCT)-derived coronary artery calcium scores correlate with the extent of atherosclerosis, but there is a substantial variance about the general relationship between coronary calcification and coronary atherosclerosis. The relationship between calcification and atherosclerosis may also differ ...
journal_title:Journal of computer assisted tomography
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004728-199803000-00008
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:The purpose of this article is to report computed tomography demonstration of medial bowing of the lamina papyracea in 5 patients after internal ethmoidectomy. METHODS:We identified 5 patients who had apparent medial bowing of the lamina papyracea after functional endoscopic sinus surgery (FESS) and who had ...
journal_title:Journal of computer assisted tomography
pub_type: 临床试验,杂志文章
doi:10.1097/RCT.0b013e31816c82da
更新日期:2009-01-01 00:00:00
abstract::MRI appearance of adult polyglucosan body disease is described. A 67-year-old man presenting with a chronic progressive degenerative neurologic disorder was found to have marked atrophy of the entire cord, without signal abnormalities on long TR images. Autopsy revealed atrophy of the cord, diffuse gliosis, and numero...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199209000-00028
更新日期:1992-09-01 00:00:00
abstract:PURPOSE:High resolution MR images obtained from a normal human volunteer at 8 T are utilized to describe the appearance of iron-containing deep gray nuclei at this field strength. METHOD:High resolution (1,024 x 1,024 matrix) near-axial gradient echo images of the deep gray nuclei were acquired on a human volunteer by...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199911000-00009
更新日期:1999-11-01 00:00:00
abstract::Radiographic evaluation of the penis is difficult and essentially limited to invasive studies. We report cases of idiopathic and iatrogenic corpora cavernosa thromboses diagnosed by magnetic resonance imaging. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198807000-00012
更新日期:1988-07-01 00:00:00
abstract::Three patients are presented in whom computed tomography incidentally demonstrated low density masses posterior to, but separate from, the right kidney. In two, these were proven to represent unilocular cysts, and the third is presumed cystic. Possible etiologies are discussed. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1979-12-01 00:00:00
abstract::This paper will review the lumbosacral spine (L1-S5). Procedures performed in the lumbosacral spine include electromyography, spinal stimulator implants, spinal infusion implants for spasticity or pain medications, sacroiliac spine injections, facet blocks, and steroid injections. Complications from these procedures i...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181560a51
更新日期:2007-09-01 00:00:00
abstract:PURPOSE:Phase-contrast cine magnetic resonance imaging (PC-MRI) is a widely used technique for determination of possible communication of arachnoid cysts (ACs). Three-dimensional (3D) sampling perfection with application-optimized contrasts using different flip-angle evolutions (3D-SPACE) technique is a relatively new ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000751
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:We have devised, implemented, and tested a technique for creating a comprehensive probabilistic atlas of the human cerebral cortex, based on high-dimensional fluid transformations. The goal of the atlas is to detect and quantify subtle and distributed patterns of deviation from normal cortical anatomy, in a 3D ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199707000-00008
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to develop and validate a novel noise insertion method that can accurately simulate lower-dose images from existing standard-dose computed tomography (CT) data. METHODS:The noise insertion method incorporates the effects of the bowtie filter, automatic exposure control, and el...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318258e891
更新日期:2012-07-01 00:00:00
abstract::This study illustrates detailed cerebral anatomy that can be consistently visualized on computed tomography scans after a rapid high dose of contrast substance has been infused. A thorough knowledge of anatomy is required not only to detect and precisely localize lesions but to avoid ascribing pathological significan...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197904000-00001
更新日期:1979-04-01 00:00:00
abstract::The density distribution inside a pathologic zone before and after contrast enhancement has been studied in the computed tomograms of 88 cases of cerebral and orbital tumors, using histographic analysis. The histograms provided additional diagnostic information, especially for vascular tumors. This method is also usef...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197704000-00014
更新日期:1977-04-01 00:00:00