Abstract:
OBJECTIVE:MRI offers many opportunities for noninvasive in vivo measurement of structure-function relationships in the human brain. Although automated methods are now available for whole-brain measurements, an efficient and valid automatic method for volume estimation of subregions such as the frontal or temporal lobes is still needed. MATERIALS AND METHODS:We adapted the Talairach atlas to the study of brain subregions. We supplemented the atlas with additional boxes to include the cerebellum. We assigned all the boxes to 1 of 12 regions of interest (ROIs) (frontal, parietal, temporal, and occipital lobes, cerebellum, and subcortical regions on right and left sides of the brain). Using T1-weighted MR scans collected with an SPGR sequence (slice thickness = 1.5 mm), we manually traced these ROIs and produced volume estimates. We then transformed the scans into Talairach space and compared the volumes produced by the two methods ("traced" versus "automatic"). The traced measurements were considered to be the "gold standard" against which the automatic measurements were compared. RESULTS:The automatic method was found to produce measurements that were nearly identical to the traced method. We compared absolute measurements of volume produced by the two methods, as well as the sensitivity and specificity of the automatic method. We also compared the measurements of cerebral blood flow obtained through [15O]H2O PET studies in a sample of nine subjects. Absolute measurements of volume produced by the two methods were very similar, and the sensitivity and specificity of the automatic method were found to be high for all regions. The flow values were also found to be very similar by both methods. CONCLUSION:The automatic atlas-based method for measuring the volume of brain subregions produces results that are similar to manual techniques. The method is rapid, efficient, unbiased, and not subject to the problems of rater drift or potentially poor interrater reliability that plague manual methods. Consequently, this method may be very useful for the study of structure-function relationships in the human brain.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Andreasen NC,Rajarethinam R,Cizadlo T,Arndt S,Swayze VW 2nd,Flashman LA,O'Leary DS,Ehrhardt JC,Yuh WTdoi
10.1097/00004728-199601000-00018subject
Has Abstractpub_date
1996-01-01 00:00:00pages
98-106issue
1eissn
0363-8715issn
1532-3145journal_volume
20pub_type
杂志文章abstract::Weighting is the term most frequently used to describe magnetic resonance pulse sequences and the concept most commonly used to relate image contrast to differences in magnetic resonance tissue properties. It is generally used in a qualitative sense with the single tissue property thought to be most responsible for th...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/RCT.0b013e3181d3449a
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:This study aimed to investigate the effectiveness and additive value of T2W 3-dimensional sampling perfection with application optimized contrast (3D-SPACE) with variant flip-angle mode in imaging of all types of hydrocephalus. Our secondary objective was to assess the reliability of 3D-SPACE sequence and corre...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000206
更新日期:2015-05-01 00:00:00
abstract::We report a patient with gas in the pancreatic duct due to a gastropancreatic fistula resulting from gastric ulcer. No mass or pseudocyst was demonstrated. This entity should be considered when patients with gas in the pancreas are encountered. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198707000-00031
更新日期:1987-07-01 00:00:00
abstract::Ten consecutive patients with surgically proven beta-islet cell tumors, strongly suspected clinically because of positive laboratory findings, were studied by MRI at 0.5 T. Results were correlated with CT and angiography. MRI detected all 10 insulinomas, with the location confirmed at surgery. Lesion size was < 1 cm i...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199305000-00012
更新日期:1993-05-01 00:00:00
abstract:OBJECTIVES:: The aim of this study was to achieve the quantitative analysis of the characteristic computed tomography (CT) findings and course of interstitial pneumonia using the volume histogram method. METHODS:: Contrast (CNT), variance (VAR), and entropy (EPY) values from whole-lung volume data were compared betwee...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200603000-00014
更新日期:2006-03-01 00:00:00
abstract::The anatomy of 60 right and 80 left normal suprarenal (adrenal) glands in 90 patients was studied. In the transaxial view, the glands have a triradiate shape, which varies on serial sections. The medial posterior limbs of each gland were visualized on the more cranial sections. The transaxial positions of the glands a...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197801000-00001
更新日期:1978-01-01 00:00:00
abstract:OBJECTIVE:Our goal was to evaluate the role of Gd-enhanced MR in the diagnosis and surgical planning of intraventricular cysticercosis cysts. MATERIALS AND METHODS:Thirty-three patients with intraventricular cysticercosis were evaluated with Gd-enhanced MRI including follow-up studies ranging over time periods from 6 ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199311000-00015
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE:Compared the performance of computer-aided detection (CAD) software for quantitative analysis of airway using computed tomography (CT) images reconstructed with versions of model-based iterative reconstruction (MBIR) that either balances spatial and density resolution (MBIRSTND) or prefers spatial resolution ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000975
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:The goal of this study was to quantify changes in uterine volume during and after chemotherapy for breast cancer. MATERIALS AND METHODS:Fifty-eight patients (mean age 42 years) with advanced breast cancer undergoing treatment with FLAC (5-fluorouracil, leucovorin, Adriamycin, and cyclophosphamide) were studi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199507000-00016
更新日期:1995-07-01 00:00:00
abstract::We describe a patient in whom a secondary aortocaval fistula was diagnosed on dynamic CT by noting transient enhancement of the inferior vena cava simultaneously with maximum enhancement of the aorta. This pattern of caval enhancement is contrasted with the gradual increase and subsequent plateauing of caval opacifica...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198703000-00031
更新日期:1987-03-01 00:00:00
abstract::An unusual computed tomography finding, the "target sign," is demonstrated in a patient with a corpus callosum tumor mass extending to the right lateral ventricle. The central low attenuation of the "target" is produced by the isolated part of the dilated lateral ventricle surrounded by tumor tissue, the dense area of...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1979-08-01 00:00:00
abstract::Mean lung density (MLD), as determined by a chest computed tomographic sector method, was evaluated in 12 patients with sarcoidosis and diffuse interstitial lung disease. The results demonstrate that MLD in sarcoidosis was -610.9 +/- 57.3 Hounsfield units (HU), significantly different (p less than 0.001) from a contro...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198306000-00003
更新日期:1983-06-01 00:00:00
abstract::Computed tomography circumvents many of the problems encountered in the traditional radiographic investigation of mummies. This case report demonstrates that CT provides an improved evaluation of mummification techniques and bony pathology as well as a better capability of characterizing preserved soft tissue. ...
journal_title:Journal of computer assisted tomography
pub_type: 历史文章,杂志文章
doi:
更新日期:1984-10-01 00:00:00
abstract::The authors present findings from a scientific study in a 36-year-old male patient who was transferred for the evaluation of a restenosis in aortic coarctation that was initially treated by surgical repair. Contrast-enhanced magnetic resonance angiography and comprehensive flow-sensitive 4-dimensional magnetic resonan...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181906766
更新日期:2009-09-01 00:00:00
abstract::Magnetic resonance is recognized as potentially the best imaging procedure for localization in stereotactic neurosurgery. However, special difficulties necessitate specific adaptation to localize targets in the stereotactic frame. We developed a new method for stereotactic localization. The MR studies were performed u...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199103000-00020
更新日期:1991-03-01 00:00:00
abstract::Multiple authors have pointed out the difficulty of detecting spondylolysis with lumbar CT. A simple method to detect spondylolysis on lumbar CT is described. Identifying one intact cortical ring for each vertebra absolutely excludes the diagnosis obviating the time-consuming need to search each image looking for posi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1985-07-01 00:00:00
abstract::Hepatic actinomycosis is an uncommon entity that forms communicating abscesses and fistulae. A case is presented in which findings on ultrasound, CT, and percutaneous injection of the abscess all reflected the pathologic process. Biopsy by thin-needle aspiration under CT guidance afforded prompt, accurate diagnosis an...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198603000-00035
更新日期:1986-03-01 00:00:00
abstract::Primary adrenal lymphoma is extremely rare. We describe 2 patients who presented with adrenal insufficiency or fever 'of unknown origin. Conventional imaging studies demonstrated bilateral bulky adrenal masses, and whole-body FDG positron emission tomography- computed tomography showed that the masses were the unique ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000216112.15564.0c
更新日期:2006-09-01 00:00:00
abstract::Thirty-three patients with rheumatoid arthritis had computed tomographic examination of the craniocervical junction. This demonstrated soft tissue features which have not previously been described in published reports. A low attenuation lesion between the odontoid and the transverse ligament shown in 11 patients was c...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198302000-00006
更新日期:1983-02-01 00:00:00
abstract:OBJECTIVE:To present a novel magnetic resonance (MR) method of analysis of cerebrospinal fluid (CSF) flow dynamics. METHODS:Fifty-one subjects were explored with phase-contrast cine MR imaging. There were 36 volunteers, 9 patients with normal pressure hydrocephalus (NPH), and 6 patients with asymptomatic ventricular d...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200403000-00015
更新日期:2004-03-01 00:00:00
abstract::We present a patient with a progressively enlarging adrenal mass detected by CT which extended to the renal hilum and inferior vena cava. Pathologic evaluation revealed an adrenal abscess containing purulent debris. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198705000-00040
更新日期:1987-05-01 00:00:00
abstract:PURPOSE:The purpose of this work was to demonstrate the variety of causes of crazy-paving appearance (CPA) on high resolution CT (HRCT). METHOD:To identify cases exhibiting CPA (ground-glass opacity with superimposed interlobular septal thickening and intralobular interstitial thickening) on HRCT, we prospectively sea...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199909000-00021
更新日期:1999-09-01 00:00:00
abstract::The primitive trigeminal artery is the most common of the persistent carotid-basilar anastomoses with an angiographic incidence of 0.6%. Fifteen cases of aneurysms of a persistent primitive trigeminal artery have been reported in the literature. A 16th patient is presented in whom an incidental trigeminal artery aneur...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-198809010-00022
更新日期:1988-09-01 00:00:00
abstract:PURPOSE:The purpose of this work was to determine the accuracy of predicting arterial enhancement from peripheral versus central venous test bolus injections at CT angiography (CTA). METHOD:In 40 patients with abdominal aortic aneurysms, aortoiliac enhancement profiles were predicted by mathematical deconvolution of t...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200103000-00024
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the accuracy of dynamic laryngeal computed tomography (DLCT) for the detection of vocal cord mobility in larynx cancer. METHODS:Vocal cord mobility of 44 patients (36 men; age range, 49-81 years) with larynx cancer was examined; 13 patients were excluded (owing to poor image quality or bilateral ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e31825b85ce
更新日期:2012-07-01 00:00:00
abstract::We conducted a prospective evaluation of the normal vermiform appendix in 203 patients. Conventional CT techniques were utilized with an 8 mm slice thickness and 10 mm slice interval. The normal appendix was definitely identified in 51% of the patients studied. Computed tomographic appearance of the normal appendix is...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199107000-00009
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:To determine the normal anatomical features and variations of the bronchial arterial system and to determine the relationship among ectopic bronchial arteries, location (right-left) of the bronchial arteries, and variations of the aortic arch in patients as well as the sex of the patients who underwent multid...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3182073c27
更新日期:2011-03-01 00:00:00
abstract::Contrast enhancement has been studied with computed tomography in 18 patients with brain infarction. Four patients were examined on more than one occasion. A mode of contrast medium administration has been used that results in constant blood iodine concentration during the investigation. The enhancement pattern was an...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197904000-00016
更新日期:1979-04-01 00:00:00
abstract:OBJECTIVE:We applied glucose loading during PET studies with [18F]2-fluoro-2-deoxy-D-glucose (FDG) to enhance detection of brain tumors by diminution of FDG uptake in normal gray matter. MATERIALS AND METHODS:This study involved three patients with glioblastomas. Two PET scans were performed in all cases within 1 week...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199401000-00003
更新日期:1994-01-01 00:00:00
abstract::Three surgically proven cases of lumbar extradural juxtaarticular cysts were examined by magnetic resonance (MR) imaging. The highly variable MR signal patterns are presented. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199005000-00018
更新日期:1990-05-01 00:00:00