Enhanced detection of brain tumors by [18F]fluorodeoxyglucose PET with glucose loading.

Abstract:

OBJECTIVE:We applied glucose loading during PET studies with [18F]2-fluoro-2-deoxy-D-glucose (FDG) to enhance detection of brain tumors by diminution of FDG uptake in normal gray matter. MATERIALS AND METHODS:This study involved three patients with glioblastomas. Two PET scans were performed in all cases within 1 week in control and with glucose loading state. RESULTS:In all patients, tumor was depicted more clearly with glucose loading than in the control study. The FDG uptake ratio of tumor to normal cortical gray matter showed a mean increase of 27% with glucose loading. CONCLUSION:This technique might be useful for detection of recurrent or residual tumors.

journal_name

J Comput Assist Tomogr

authors

Ishizu K,Sadato N,Yonekura Y,Nishizawa S,Magata Y,Tamaki N,Tsuchida T,Okazawa H,Tanaka F,Miyatake S

doi

10.1097/00004728-199401000-00003

subject

Has Abstract,Author List Incomplete

pub_date

1994-01-01 00:00:00

pages

12-5

issue

1

eissn

0363-8715

issn

1532-3145

journal_volume

18

pub_type

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