Quantitative analysis for computed tomography findings of various diffuse lung diseases using volume histogram analysis.

Abstract:

OBJECTIVES:: The aim of this study was to achieve the quantitative analysis of the characteristic computed tomography (CT) findings and course of interstitial pneumonia using the volume histogram method. METHODS:: Contrast (CNT), variance (VAR), and entropy (EPY) values from whole-lung volume data were compared between normal lungs and 5 diseases that have characteristic CT findings. Thirteen cases with nonspecific interstitial pneumonia (NSIP) were evaluated before and after treatment. RESULTS:: In cases with thickening of the bronchovascular bundles and interlobular thickening, ground-glass attenuation, airspace consolidation, and honeycombing, the values of VAR and EPY were greater than those in the normal cases (P < 0.05). In the cases with NSIP, the CNT value after treatment was significantly greater and the values of VAR and EPY after treatment were significantly lower than those before treatment (P < 0.05). CONCLUSIONS:: Volume histogram analysis is a promising method for the evaluation of diffuse lung diseases and the effectiveness of treatment.

journal_name

J Comput Assist Tomogr

authors

Sumikawa H,Johkoh T,Yamamoto S,Takahei K,Ueguchi T,Ogata Y,Matsumoto M,Fujita Y,Natsag J,Inoue A,Tsubamoto M,Mihara N,Honda O,Tomiyama N,Hamada S,Nakamura H

doi

10.1097/00004728-200603000-00014

subject

Has Abstract

pub_date

2006-03-01 00:00:00

pages

244-9

issue

2

eissn

0363-8715

issn

1532-3145

pii

00004728-200603000-00014

journal_volume

30

pub_type

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