Comparison and evaluation of rigid, affine, and nonrigid registration of breast MR images.

Abstract:

PURPOSE:A new nonrigid registration method, designed to reduce the effect of movement artifact in subtraction images from breast MR, is compared with existing rigid and affine registration methods. METHOD:Nonrigid registration was compared with rigid and affine registration methods and unregistered images using 54 gadolinium-enhanced 3D breast MR data sets. Twenty-seven data sets had been previously reported normal, and 27 contained a histologically proven carcinoma. The comparison was based on visual assessment and ranking by two radiologists. RESULTS:When analyzed by two radiologists independently, all three registration methods gave better-quality subtraction images than unregistered images (p < 0.01), but nonrigid registration gave significantly better results than the rigid and affine registration methods (p < 0.01). There was no significant difference between rigid and affine registration methods. CONCLUSION:Nonrigid registration significantly reduces the effects of movement artifact in subtracted contrast-enhanced breast MRI. This may enable better visualization of small tumors and those within a glandular breast.

journal_name

J Comput Assist Tomogr

authors

Denton ER,Sonoda LI,Rueckert D,Rankin SC,Hayes C,Leach MO,Hill DL,Hawkes DJ

doi

10.1097/00004728-199909000-00031

keywords:

subject

Has Abstract

pub_date

1999-09-01 00:00:00

pages

800-5

issue

5

eissn

0363-8715

issn

1532-3145

journal_volume

23

pub_type

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