Computed tomographic distinction of perirenal liposarcoma from exophytic angiomyolipoma: a feature analysis study.

Abstract:

PURPOSE:To identify computed tomographic (CT) findings that distinguish perirenal liposarcomas from exophytic angiomyolipomas. MATERIALS AND METHODS:We identified CT scans of 20 patients (13 women and 7 men; mean age, 63 years) with either perirenal liposarcoma (n = 11) proven at histopathology or large exophytic angiomyolipomas (n = 9) determined by 2-year stability (n = 6) or histopathology (n = 3). Two independent readers unaware of the final diagnoses recorded the presence of the following CT findings: (1) tumoral vessel extending into the renal cortex, (2) tumoral vessel extending into the renal hilum, (3) renal parenchymal defect at the site of tumor contact, (4) intratumoral hemorrhage, (5) nonfat attenuating intratumoral nodules, and (6) calcification. RESULTS:A tumoral vessel extending into the renal cortex was seen only in angiomyolipomas (7 and 6 of 9 patients versus 0 and 0 of 11 liposarcomas for readers 1 and 2, respectively; P < 0.005 for both). A parenchymal defect was more commonly seen in angiomyolipomas (7 and 6 of 9 angiomyolipomas versus 1 and 1 of 11 liposarcomas for readers 1 and 2, respectively; P < 0.05 for both). Calcifications were seen by both readers in 6 of 11 liposarcomas but not in any angiomyolipomas (P < 0.05). The other recorded findings were not useful in distinguishing CT features (P > 0.1 for both readers). CONCLUSIONS:In the evaluation of a fatty perinephric mass at CT, the presence of a tumoral vessel extending into the renal cortex or a renal parenchymal defect at the site of tumor contact strongly favors the diagnosis of exophytic angiomyolipoma, whereas calcifications suggest liposarcoma.

journal_name

J Comput Assist Tomogr

authors

Ellingson JJ,Coakley FV,Joe BN,Qayyum A,Westphalen AC,Yeh BM

doi

10.1097/RCT.0b013e3181507534

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

548-52

issue

4

eissn

0363-8715

issn

1532-3145

pii

00004728-200807000-00009

journal_volume

32

pub_type

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