Abstract:
OBJECTIVE:This study aimed to observe the value of computed tomography (CT) spectral imaging parameters in the diagnosis of solitary pulmonary nodules, during the contrast-enhanced early phase and late phase. MATERIALS AND METHODS:This study was approved by the institutional review board and written informed consent was obtained from all patients. One hundred thirty-nine patients with solitary pulmonary nodules proved by pathology underwent double-phase enhanced CT scan using gemstone spectral imaging mode on a Discovery CT750 HD, and were divided into an active inflammatory group (43 cases), a malignant group (65 cases), and a tuberculosis group (31 cases). The slope rate was calculated from the spectral curve. Iodine concentrations (ICs) were derived from iodine-based material decomposition CT images and normalized to the IC in the aorta. The Kruskal-Wallis test and Nemenyi test were performed to compare quantitative parameters among the 3 groups or between each of the 2 groups. RESULTS:There were significant differences in the slope rate, IC, and normalized IC (NIC) among the 3 groups. In the active inflammatory group, malignant group, and tuberculosis group, the mean slope rate were 3.03 ± 0.71 (SD), 1.96 ± 0.91, and 1.37 ± 0.43, respectively, during the early phase and 3.28 ± 0.67, 2.24 ± 0.82, and 1.67 ± 0.64, respectively, during the late phase. The ICs were 2.68 mg/mL ± 0.56, 1.65 mg/mL ± 0.76, and 1.10 mg/mL ± 0.34, respectively, during the early phase and 2.79 mg/mL ± 0.57, 1.90 mg/mL ± 0.71, and 1.29 mg/mL ± 0.44, respectively, during the late phase. The NIC were 0.24 ± 0.06, 0.16 ± 0.04, and 0.10 ± 0.04, respectively, during the early phase and 0.57 ± 0.10, 0.43 ± 0.11, and 0.25 ± 0.09, respectively, during the late phase. The mean slope rate, IC, and NIC for the active inflammatory group were significantly higher than these parameters for the malignant group (P < 0.05), and the parameters for malignant group were significantly higher than the tuberculosis group (P < 0.05). CONCLUSIONS:Dual-energy CT gemstone spectral imaging provides a novel method to better characterize pulmonary nodules in double-phase contrast-enhanced scanning.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Lin JZ,Zhang L,Zhang CY,Yang L,Lou HN,Wang ZGdoi
10.1097/RCT.0000000000000469subject
Has Abstractpub_date
2016-11-01 00:00:00pages
907-911issue
6eissn
0363-8715issn
1532-3145journal_volume
40pub_type
杂志文章abstract::The incidence of melanoma has risen dramatically over the past several decades. Oncologists rely on the ability of radiologists to identify subtle radiographic changes representing metastatic and recurrent melanoma in uncommon locations on multidetector computed tomography (MDCT) as the front-line imaging surveillance...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/RCT.0000000000000697
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:The goal of this study was twofold: first, to quantify the influence of magnetic field strength (B0) on T2* and T2susceptibility relaxation rates in vertebral bone marrow; and second, to determine the significance of in-phase/out-of-phase phenomena in GE MRI as a function of TEs at different B0 values. MATER...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199505000-00023
更新日期:1995-05-01 00:00:00
abstract:PURPOSE:Our goal was to examine the effects of collimation width (CW), pitch, viewing plane, and windowing on the display of in-plane vessels in maximum intensity projection (MIP). METHOD:A theoretical concept based on partial volume averaging of vessels was developed to describe the contents of voxels (densities) in ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199611000-00018
更新日期:1996-11-01 00:00:00
abstract::We intend to describe the imaging findings of sudden cardiac arrest occurring during computed tomographic (CT) examination and also of impending cardiogenic shock in 4 patients. Despite rare reports of acute cardiac arrest occurring during or shortly after CT scan, CT features are quite characteristic. Familiarity wit...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318250a8bc
更新日期:2012-05-01 00:00:00
abstract::The computed tomographic findings in seven boys and two girls with infarction of the internal capsule are reported. Ages at the time of examination ranged from 8 months to 14 years. The etiology was head injury (concussion) in six and unknown in three. Cerebral angiography carried out in four cases showed narrowing of...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198012000-00007
更新日期:1980-12-01 00:00:00
abstract::The CT findings of multiple lipid-containing dermal cysts in a patient with steatocystoma multiplex are presented. The characteristic locations, shapes, and densities of the cysts in this rare skin disorder are discussed. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198603000-00043
更新日期:1986-03-01 00:00:00
abstract::An enterogenous cyst of the craniocervical region producing anterior medullary compression is reported. The patient presented with quadriparesis with greater involvement of the upper limbs. Computed tomography showed a high attenuation intradural extramedullary mass located anteriorly. Magnetic resonance imaging demon...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199005000-00030
更新日期:1990-05-01 00:00:00
abstract::The computed tomographic demonstration of a glomus jugulare tumor with two unusual radiographic features--multiple pulmonary metastases and extension of the tumor into the cerebellopontine angle--is presented. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198006000-00022
更新日期:1980-06-01 00:00:00
abstract::Four patients with blunt abdominal trauma underwent computed tomography (CT) as part of their diagnostic evaluation. In each case CT accurately demonstrated the pathology and the extent of injury. The results suggest that routine use of CT scanning may be an effective screening modality in the traumatized patient. It ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1979-02-01 00:00:00
abstract:OBJECTIVES:To retrospectively determine, by using multislice computed tomography (MSCT), whether additional interpretation of sliding-thin-slab maximum-intensity projection (MIP) reformation images improve diagnostic accuracy when compared with the diagnostic interpretation of conventional sliding-thin-slab multiplanar...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e31815ba1cd
更新日期:2008-11-01 00:00:00
abstract:PURPOSE:To evaluate the agreement and correlation between attenuation values and vascular calcification volume for intra-abdominal structures from true noncontrast (TNC) images and those from virtual noncontrast (VNC) images obtained by dual-source dual-energy computed tomography (CT) using a quadriphasic dynamic proto...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000001057
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:The purpose of this study was to investigate the noninvasive quantification of coronary artery stenosis using cardiac software packages and vessel phantoms with known stenosis severity. MATERIALS AND METHODS:Four different sizes of vessel phantoms were filled with contrast agent and scanned on a 64-slice multi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181888363
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:The purpose of this study was to compare quantitative and qualitative measures of aortic, cardiac, and respiratory motion artifact between high-pitch dual-source (DS) and single-source (SS) computed tomography pulmonary angiography (CTPA) protocols. METHODS:This institutional review board-approved, Health Insu...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000736
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to demonstrate the feasibility of whole-body diffusion tensor imaging (DTI) as a promising tool for research applications, for instance, for investigation of systemic muscle diseases. MATERIALS AND METHODS:Twelve healthy volunteers (mean age, 26.6 years; range, 20-39 years) underwen...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000324
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:The purpose of this work was to determine the range of normal measurements for the thyroid gland on chest CT scans and relate it to the dimensions of the trachea. METHOD:Chest CT scans in 118 patients were examined prospectively for visibility of the thyroid gland and its relationship to the trachea. The great...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200205000-00005
更新日期:2002-05-01 00:00:00
abstract:PURPOSE:The goal of this work was to evaluate three-dimensional (3D) contrast-enhanced MR angiography (MRA) for the detection of ostial stenoses of the aortic arch. METHOD:Sixteen patients with suspected carotid atherosclerotic disease prospectively underwent digital subtraction angiography of the aortic arch followed...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200005000-00003
更新日期:2000-05-01 00:00:00
abstract:OBJECTIVE:This study aimed to determine optimal strength of sinogram-affirmed iterative reconstruction (SAFIRE) and to evaluate image quality (IQ) of low-dose chest computed tomography (LDCT) using SAFIRE compared with iterative reconstruction in image space (IRIS) and filtered back projection (FBP). METHODS:Thirty pa...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e31828f4dae
更新日期:2013-07-01 00:00:00
abstract::We present a case series of the MR findings of destructive tears of the Achilles tendon secondary to overlying soft tissue ulcerations. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200011000-00016
更新日期:2000-11-01 00:00:00
abstract::Recurrent respiratory papillomatosis is a chronic disease of children and young adults associated with various complications, one of which is malignant change. We report CT findings of malignant change in a case of recurrent respiratory papillomatosis. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199509000-00020
更新日期:1995-09-01 00:00:00
abstract::Computed tomography scans of the larynx were obtained during quiet breathing and during phonation in 10 volunteers having no neck or larynx abnormalities. The subglottic and glottic laryngeal cavity and soft tissues showed symmetry from side to side. At the supraglottic level, the pliable aryepiglottic folds and pyrif...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198106000-00008
更新日期:1981-06-01 00:00:00
abstract::We describe a patient with CT-proven ischemic infarction of the left middle cerebral artery (MCA) territory. The emergency CT, on admission, was suggestive of intracranial internal carotid artery dissection by demonstrating gaseous gap defects in the arterial wall and a subsequent thromboembolic process in the MCA. To...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-200211000-00015
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the usefulness of T2 mapping for detecting myocardial injuries in patients with hypertrophic cardiomyopathy (HCM). METHODS:Twenty-one HCM patients and 7 healthy volunteers were examined. The T2 values were measured at hyperintense areas (high-T2 areas) identified with T2...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000521
更新日期:2017-05-01 00:00:00
abstract::Serial computed tomography (CT) demonstrated complete resolution of severe periventricular hypodensity occurring in a child after receiving prophylaxis for acute lymphocytic leukemia. The resolution of this encephalopathy suggests that early changes of subacute necrotizing leukoencephalopathy are reversible and CT is ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197809000-00023
更新日期:1978-09-01 00:00:00
abstract::A case of isolated spinal cord hemangioblastoma with associated extensive syringohydromyelia, which was evaluated by myelography, postmyelographic CT, magnetic resonance (MR), and angiography is presented. The specific preoperative and postoperative advantages of MR are given as well as a brief review of the literatur...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198805010-00028
更新日期:1988-05-01 00:00:00
abstract:OBJECTIVE:The goal of this study was to quantify changes in uterine volume during and after chemotherapy for breast cancer. MATERIALS AND METHODS:Fifty-eight patients (mean age 42 years) with advanced breast cancer undergoing treatment with FLAC (5-fluorouracil, leucovorin, Adriamycin, and cyclophosphamide) were studi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199507000-00016
更新日期:1995-07-01 00:00:00
abstract::Magnetic resonance elastography (MRE) has been successfully implemented in the assessment of diffuse liver diseases. Currently, MRE is the most accurate noninvasive technique for detection and staging of liver fibrosis with a potential to replace liver biopsy. Magnetic resonance elastography is able to differentiate i...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/RCT.0000000000000032
更新日期:2013-11-01 00:00:00
abstract::The subarachnoid space continues into the orbit as part of the optic nerve sheath. This space varies in size but is usually tiny. Occasionally, prominent (one case in our experience) enhancement of the optic nerve as part of metrizamide computed tomography (CT) cisternography is seen on transverse and coronal scans pr...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197910000-00015
更新日期:1979-10-01 00:00:00
abstract::We describe a case of disruption of the blood-brain barrier (BBB) by nonionic, low osmolality contrast medium after abdominal angiography. One plausible explanation of this event is that acute hypertension during angiography may have increased the BBB permeability, allowing the contrast medium to leak across it. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198909000-00027
更新日期:1989-09-01 00:00:00
abstract:PURPOSE:The objective of this study was to characterize cervical computed tomography (CT) findings in Kawasaki disease (KD) patients that may facilitate early diagnosis. METHODS:We retrospectively reviewed cervical CT images of 78 children with cervical lymphadenopathy to analyze the distribution and morphology of lym...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e31829d1965
更新日期:2013-09-01 00:00:00
abstract::The CT and magnetic resonance (MR) findings in 13 patients with advanced Zollinger-Ellison syndrome are described. In eight patients (62%) one or more primary tumors were found with both methods. All patients with proven liver metastases (n = 7) were identified by MR. Computed tomography was positive in six of these p...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198909000-00013
更新日期:1989-09-01 00:00:00